Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Prime Medicine, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 116
- −3 vs. Q2 2024
- Shares held
- 68.7M
- +5.01M (+7.9%) vs. Q2 2024
- Total value
- $265.9M
- −$61.5M (−18.8%) vs. Q2 2024
- New holders
- 15
- 38 more added
- Sold out
- 18
- 33 more reduced
3 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM, LLC | 22 | $0 | 0.00% | −304−93.3% | Reduced |
| Lazard Asset Management LLC | 26 | $0 | 0.00% | −46−63.9% | Reduced |
| Covestor Ltd | 13 | $0 | 0.00% | −1−7.1% | Reduced |
| Federated Hermes, Inc. | 4 | $15 | 0.00% | +4 | New |
| Farther Finance Advisors, LLC | 26 | $101 | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 28 | $108 | 0.00% | −86−75.4% | Reduced |
| Russell Investments Group, Ltd. | 52 | $201 | 0.00% | −29−35.8% | Reduced |
| Sterling Capital Management LLC | 58 | $224 | 0.00% | +58 | New |
| EverSource Wealth Advisors, LLC | 106 | $410 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 109 | $422 | 0.00% | −7,627−98.6% | Reduced |
| SRS Capital Advisors, Inc. | 139 | $538 | 0.00% | 00.0% | Unchanged |
| Principal Securities, Inc. | 280 | $1.08K | 0.00% | +115+69.7% | Added |
| Comerica Bank | 315 | $1.22K | 0.00% | −181−36.5% | Reduced |
| Fairman Group, LLC | 500 | $1.94K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 398 | $2.00K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 654 | $2.53K | 0.00% | +422+181.9% | Added |
| Quadrant Capital Group LLC | 966 | $3.74K | 0.00% | +966 | New |
| First Horizon Advisors, Inc. | 1,109 | $4.29K | 0.00% | −25−2.2% | Reduced |
| Abich Financial Wealth Management LLC | 1,247 | $4.83K | 0.01% | +941+307.5% | Added |
| Amalgamated Bank | 1,347 | $5.00K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 1,410 | $5.46K | 0.00% | +410+41.0% | Added |
| Mirae Asset Global Investments Co., Ltd. | 4,341 | $15.0K | 0.00% | +757+21.1% | Added |
| Ameritas Investment Partners, Inc. | 3,901 | $15.1K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 4,110 | $15.9K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 4,522 | $17.5K | 0.00% | −1,678−27.1% | Reduced |
| Legal & General Group Plc | 6,279 | $24.3K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 8,049 | $31.1K | 0.00% | +2,892+56.1% | Added |
| New York State Common Retirement Fund | 8,434 | $32.6K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 9,901 | $38.3K | 0.00% | −800−7.5% | Reduced |
| Brown Brothers Harriman & Co | 10,065 | $39.0K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 10,222 | $40.0K | 0.00% | −1,113−9.8% | Reduced |
| Royal Bank of Canada | 10,685 | $41.0K | 0.00% | +4,547+74.1% | Added |
| Acadian Asset Management LLC | 10,886 | $42.0K | 0.00% | +10,886 | New |
| State Board of Administration of Florida Retirement System | 11,420 | $44.2K | 0.00% | 00.0% | Unchanged |
| Paloma Partners Management Co | 11,587 | $44.8K | 0.00% | +11,587 | New |
| Virtus ETF Advisers LLC | 11,670 | $45.2K | 0.02% | +211+1.8% | Added |
| Invesco Ltd. | 14,023 | $54.3K | 0.00% | +586+4.4% | Added |
| Intech Investment Management LLC | 14,102 | $54.6K | 0.00% | +14,102 | New |
| Pathstone Holdings, LLC | 14,370 | $55.6K | 0.00% | +14,370 | New |
| Clarius Group, LLC | 16,080 | $62.2K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 17,811 | $68.9K | 0.00% | +5,104+40.2% | Added |
| Oppenheimer & Co Inc | 17,871 | $69.2K | 0.00% | −3,160−15.0% | Reduced |
| Voya Investment Management LLC | 19,184 | $74.2K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 20,000 | $77.4K | 0.00% | +20,000 | New |
| Corsair Capital Management, L.P. | 20,000 | $77.4K | 0.02% | +20,000 | New |
| HighTower Advisors, LLC | 21,675 | $83.0K | 0.00% | −559−2.5% | Reduced |
| China Universal Asset Management Co., Ltd. | 23,086 | $89.3K | 0.01% | +8,985+63.7% | Added |
| Benjamin Edwards Inc | 23,196 | $89.6K | 0.00% | +23,010+12,371.0% | Added |
| Manufacturers Life Insurance Company, The | 23,395 | $90.5K | 0.00% | −743−3.1% | Reduced |
| Voloridge Investment Management, LLC | 27,119 | $105.0K | 0.00% | −18,634−40.7% | Reduced |
| Davy Global Fund Management Ltd | 28,113 | $108.8K | 0.01% | +9,199+48.6% | Added |
| Envestnet Asset Management Inc | 28,355 | $109.7K | 0.00% | +6,695+30.9% | Added |
| Ameriprise Financial Inc | 28,801 | $111.5K | 0.00% | −1,095−3.7% | Reduced |
| Levin Capital Strategies, L.P. | 30,000 | $116.1K | 0.01% | +30,000 | New |
| Corebridge Financial, Inc. | 30,325 | $117.4K | 0.00% | −187−0.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 31,127 | $120.5K | 0.00% | +11,603+59.4% | Added |
| MetLife Investment Management | 34,128 | $132.1K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 35,021 | $135.5K | 0.00% | +12,482+55.4% | Added |
| JPMorgan Chase & Co | 37,382 | $144.7K | 0.00% | −805−2.1% | Reduced |
| Verition Fund Management LLC | 38,545 | $149.2K | 0.00% | +38,545 | New |
| TD Asset Management Inc | 46,434 | $160.7K | 0.00% | 00.0% | Unchanged |
| PEAK6 Investments LLC | 45,013 | $174.2K | 0.01% | +11,013+32.4% | Added |
| SG Americas Securities, LLC | 46,982 | $182.0K | 0.00% | +46,982 | New |
| Citigroup Inc | 48,071 | $186.0K | 0.00% | +30,560+174.5% | Added |
| Citadel Advisors LLC | 50,995 | $197.4K | 0.00% | +38,269+300.7% | Added |
| Jane Street Group, LLC | 57,548 | $222.7K | 0.00% | −110,869−65.8% | Reduced |
| Rhumbline Advisers | 70,047 | $271.1K | 0.00% | −60−0.1% | Reduced |
| Alliancebernstein L.P. | 76,000 | $294.1K | 0.00% | +5,810+8.3% | Added |
| Sphera Funds Management Ltd. | 76,456 | $295.9K | 0.05% | −50,968−40.0% | Reduced |
| Chelsea Counsel Co | 78,690 | $304.5K | 0.15% | +1,000+1.3% | Added |
| Barclays PLC | 84,697 | $327.8K | 0.00% | +65,593+343.3% | Added |
| Vestmark Advisory Solutions, Inc. | 90,036 | $348.4K | 0.01% | −13,476−13.0% | Reduced |
| Gsa Capital Partners LLP | 99,060 | $383.0K | 0.03% | +99,060 | New |
| Walleye Capital LLC | 108,374 | $419.4K | 0.00% | +108,374 | New |
| Deutsche Bank AG | 114,907 | $444.7K | 0.00% | −346,088−75.1% | Reduced |
| Susquehanna International Group, LLP | 115,054 | $445.3K | 0.00% | +9,162+8.7% | Added |
| Two Sigma Advisers, LP | 119,900 | $464.0K | 0.00% | −56,600−32.1% | Reduced |
| Squarepoint Ops LLC | 124,369 | $481.3K | 0.00% | +60,908+96.0% | Added |
| Bank of New York Mellon Corp | 129,714 | $502.0K | 0.00% | −40,849−23.9% | Reduced |
| FIL Ltd | 129,861 | $502.6K | 0.00% | −8,415−6.1% | Reduced |
| D. E. Shaw & Co., Inc. | 139,451 | $539.7K | 0.00% | +94,016+206.9% | Added |
| Wells Fargo & Company | 171,468 | $663.6K | 0.00% | +151,110+742.3% | Added |
| Goldman Sachs Group Inc | 220,144 | $852.0K | 0.00% | +140,777+177.4% | Added |
| Trexquant Investment LP | 242,160 | $937.2K | 0.01% | +13,945+6.1% | Added |
| Morgan Stanley | 300,391 | $1.16M | 0.00% | +116,426+63.3% | Added |
| Two Sigma Investments, LP | 318,573 | $1.23M | 0.00% | −362,903−53.3% | Reduced |
| Bollard Group LLC | 361,136 | $1.40M | 0.04% | 00.0% | Unchanged |
| Casdin Capital, LLC | 367,175 | $1.42M | 0.09% | 00.0% | Unchanged |
| Nuveen Asset Management, LLC | 392,443 | $1.52M | 0.00% | 00.0% | Unchanged |
| Westwood Holdings Group Inc. | 449,476 | $1.74M | 0.01% | +90,896+25.3% | Added |
| Charles Schwab Investment Management Inc | 463,977 | $1.80M | 0.00% | −28,284−5.7% | Reduced |
| Bank of America Corp | 485,125 | $1.88M | 0.00% | +57,729+13.5% | Added |
| Moore Capital Management, LP | 500,000 | $1.94M | 0.06% | 00.0% | Unchanged |
| Northern Trust Corp | 524,548 | $2.03M | 0.00% | +131,031+33.3% | Added |
| Samsara BioCapital, LLC | 540,304 | $2.09M | 0.40% | 00.0% | Unchanged |
| Avidity Partners Management LP | 694,000 | $2.69M | 0.14% | 00.0% | Unchanged |
| EcoR1 Capital, LLC | 700,000 | $2.71M | 0.09% | 00.0% | Unchanged |
| Greenwich Wealth Management LLC | 733,001 | $2.84M | 0.19% | +80,000+12.3% | Added |
| Farallon Capital Management, L.L.C. | 750,000 | $2.90M | 0.02% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 896,960 | $3.47M | 0.05% | 00.0% | Unchanged |