Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2024
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 122
- +7 vs. Q1 2024
- Shares held
- 68.9M
- +2.23M (+3.3%) vs. Q1 2024
- Total value
- $354.0M
- −$112.6M (−24.1%) vs. Q1 2024
- New holders
- 26
- 45 more added
- Sold out
- 19
- 31 more reduced
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 15,062,498 | $77.4M | 3.92% | 00.0% | Unchanged |
| ARK Investment Management LLCSuperinvestorARK Invest | 6,126,773 | $31.5M | 0.28% | +133,419+2.2% | Added |
| Vanguard Group Inc | 6,078,853 | $31.2M | 0.00% | +277,408+4.8% | Added |
| BlackRock Inc. | 5,110,418 | $26.3M | 0.00% | +1,354,208+36.1% | Added |
| FMR LLC | 3,927,853 | $20.2M | 0.00% | +3,483+0.1% | Added |
| T. Rowe Price Investment Management, Inc. | 3,725,727 | $19.2M | 0.01% | +635,644+20.6% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 3,238,385 | $16.6M | 0.01% | −126,278−3.8% | Reduced |
| Nikko Asset Management Americas, Inc. | 3,238,385 | $16.5M | 0.19% | −126,278−3.8% | Reduced |
| Redmile Group, LLC | 2,074,350 | $10.7M | 0.64% | 00.0% | Unchanged |
| MWG Management Limited | 1,792,210 | $9.21M | 10.06% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 1,545,961 | $7.95M | 0.00% | −976,629−38.7% | Reduced |
| Millennium Management LLC | 1,330,927 | $6.84M | 0.01% | +895,610+205.7% | Added |
| Geode Capital Management, LLC | 1,296,523 | $6.67M | 0.00% | +379,662+41.4% | Added |
| State Street Corp | 1,103,863 | $5.67M | 0.00% | +325,081+41.7% | Added |
| Baker Bros. Advisors LP | 1,028,466 | $5.29M | 0.07% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 896,960 | $4.61M | 0.08% | +11,646+1.3% | Added |
| Farallon Capital Management, L.L.C. | 750,000 | $3.85M | 0.02% | 00.0% | Unchanged |
| EcoR1 Capital, LLC | 700,000 | $3.60M | 0.11% | 00.0% | Unchanged |
| Avidity Partners Management LP | 694,000 | $3.57M | 0.15% | −1,296,000−65.1% | Reduced |
| Two Sigma Investments, LP | 681,476 | $3.50M | 0.01% | +173,398+34.1% | Added |
| Greenwich Wealth Management LLC | 653,001 | $3.36M | 0.25% | +75,000+13.0% | Added |
| Samsara BioCapital, LLC | 540,304 | $2.78M | 0.58% | 00.0% | Unchanged |
| Moore Capital Management, LP | 500,000 | $2.57M | 0.06% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 492,261 | $2.53M | 0.00% | +194,438+65.3% | Added |
| Deutsche Bank AG | 460,995 | $2.37M | 0.00% | +440,280+2,125.4% | Added |
| Vestal Point Capital, LP | 450,000 | $2.31M | 0.17% | +90,000+25.0% | Added |
| Bank of America Corp | 427,396 | $2.20M | 0.00% | +5,976+1.4% | Added |
| Northern Trust Corp | 393,517 | $2.02M | 0.00% | +53,519+15.7% | Added |
| Nuveen Asset Management, LLC | 392,443 | $2.02M | 0.00% | +242,070+161.0% | Added |
| Casdin Capital, LLC | 367,175 | $1.89M | 0.14% | 00.0% | Unchanged |
| Bollard Group LLC | 361,136 | $1.86M | 0.05% | 00.0% | Unchanged |
| Westwood Holdings Group Inc. | 358,580 | $1.84M | 0.01% | +199,229+125.0% | Added |
| Trexquant Investment LP | 228,215 | $1.17M | 0.02% | +228,215 | New |
| Morgan Stanley | 183,965 | $945.6K | 0.00% | −14,501−7.3% | Reduced |
| Two Sigma Advisers, LP | 176,500 | $907.2K | 0.00% | +12,500+7.6% | Added |
| Bank of New York Mellon Corp | 170,563 | $876.7K | 0.00% | +64,600+61.0% | Added |
| Jane Street Group, LLC | 168,417 | $865.7K | 0.00% | +140,949+513.1% | Added |
| FIL Ltd | 138,276 | $710.7K | 0.00% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 127,424 | $655.0K | 0.11% | −77,818−37.9% | Reduced |
| Susquehanna International Group, LLP | 105,892 | $544.3K | 0.00% | +84,580+396.9% | Added |
| Vestmark Advisory Solutions, Inc. | 103,512 | $532.1K | 0.02% | −43,972−29.8% | Reduced |
| Ensign Peak Advisors, Inc | 103,190 | $530.4K | 0.00% | −46,810−31.2% | Reduced |
| Goldman Sachs Group Inc | 79,367 | $407.9K | 0.00% | +41,187+107.9% | Added |
| Chelsea Counsel Co | 77,690 | $399.3K | 0.20% | +72,690+1,453.8% | Added |
| Alliancebernstein L.P. | 70,190 | $360.8K | 0.00% | +32,240+85.0% | Added |
| Rhumbline Advisers | 70,107 | $360.3K | 0.00% | +17,595+33.5% | Added |
| Squarepoint Ops LLC | 63,461 | $326.2K | 0.00% | +3,895+6.5% | Added |
| Thrivent Financial for Lutherans | 62,093 | $319.0K | 0.00% | +62,093 | New |
| Royce & Associates LP | 60,999 | $313.5K | 0.00% | +14,785+32.0% | Added |
| Susquehanna Fundamental Investments, LLC | 49,379 | $253.8K | 0.01% | +28,204+133.2% | Added |
| PDT Partners, LLC | 49,325 | $253.5K | 0.02% | +49,325 | New |
| TD Asset Management Inc | 46,434 | $238.7K | 0.00% | −82,588−64.0% | Reduced |
| Voloridge Investment Management, LLC | 45,753 | $235.2K | 0.00% | +45,753 | New |
| D. E. Shaw & Co., Inc. | 45,435 | $233.5K | 0.00% | +18,767+70.4% | Added |
| Virtu Financial LLC | 42,741 | $220.0K | 0.02% | +42,741 | New |
| JPMorgan Chase & Co | 38,187 | $196.3K | 0.00% | −3,894−9.3% | Reduced |
| Wellington Management Group LLP | 37,646 | $193.5K | 0.00% | +37,646 | New |
| AQR Capital Management LLC | 34,268 | $176.1K | 0.00% | +34,268 | New |
| MetLife Investment Management | 34,128 | $175.4K | 0.00% | +12,866+60.5% | Added |
| PEAK6 Investments LLC | 34,000 | $174.8K | 0.01% | +17,000+100.0% | Added |
| Corebridge Financial, Inc. | 30,512 | $156.8K | 0.00% | +30,512 | New |
| Ameriprise Financial Inc | 29,896 | $153.7K | 0.00% | +29,896 | New |
| Susquehanna Portfolio Strategies, LLC | 29,247 | $150.3K | 0.01% | −87,640−75.0% | Reduced |
| Cornercap Investment Counsel Inc | 28,923 | $148.7K | 0.02% | −318−1.1% | Reduced |
| Green Alpha Advisors, LLC | 26,245 | $134.9K | 0.11% | −7,493−22.2% | Reduced |
| Benjamin F. Edwards & Company, Inc. | 25,326 | $130.0K | 0.00% | +24,899+5,831.1% | Added |
| Manufacturers Life Insurance Company, The | 24,138 | $124.1K | 0.00% | −50,790−67.8% | Reduced |
| UBS Group AG | 22,539 | $115.8K | 0.00% | −19,984−47.0% | Reduced |
| HighTower Advisors, LLC | 22,234 | $113.0K | 0.00% | −52−0.2% | Reduced |
| Envestnet Asset Management Inc | 21,660 | $111.3K | 0.00% | −1,220−5.3% | Reduced |
| Oppenheimer & Co Inc | 21,031 | $108.1K | 0.00% | +855+4.2% | Added |
| Wells Fargo & Company | 20,358 | $104.6K | 0.00% | +8,548+72.4% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 19,524 | $100.4K | 0.00% | +19,524 | New |
| Voya Investment Management LLC | 19,184 | $98.6K | 0.00% | +6,278+48.6% | Added |
| Barclays PLC | 19,104 | $98.2K | 0.00% | −8,486−30.8% | Reduced |
| Davy Global Fund Management Ltd | 18,914 | $97.2K | 0.01% | +18,914 | New |
| Citigroup Inc | 17,511 | $90.0K | 0.00% | −26,459−60.2% | Reduced |
| Alpine Global Management, LLC | 17,373 | $89.3K | 0.02% | +17,373 | New |
| Clarius Group, LLC | 16,080 | $82.7K | 0.01% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 14,101 | $72.5K | 0.01% | −8,277−37.0% | Reduced |
| Invesco Ltd. | 13,437 | $69.1K | 0.00% | +2,826+26.6% | Added |
| Citadel Advisors LLC | 12,726 | $65.4K | 0.00% | −95,472−88.2% | Reduced |
| ProShare Advisors LLC | 12,707 | $65.3K | 0.00% | −2,569−16.8% | Reduced |
| Principal Financial Group Inc | 12,187 | $62.6K | 0.00% | −5,446−30.9% | Reduced |
| Balyasny Asset Management LLC | 12,101 | $62.2K | 0.00% | +12,101 | New |
| Virtus ETF Advisers LLC | 11,459 | $58.9K | 0.03% | +11,459 | New |
| State Board of Administration of Florida Retirement System | 11,420 | $58.7K | 0.00% | +11,420 | New |
| CIBC World Markets Inc. | 11,335 | $58.0K | 0.00% | −712−5.9% | Reduced |
| Advisor Group Holdings, Inc. | 10,701 | $55.0K | 0.00% | −908−7.8% | Reduced |
| Brown Brothers Harriman & Co | 10,065 | $51.7K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 10,000 | $51.4K | 0.00% | −24,000−70.6% | Reduced |
| New York State Common Retirement Fund | 8,434 | $43.4K | 0.00% | +11+0.1% | Added |
| Nisa Investment Advisors, LLC | 7,736 | $39.8K | 0.00% | +7,702+22,652.9% | Added |
| National Bank of Canada | 6,200 | $33.9K | 0.00% | +6,200 | New |
| Legal & General Group Plc | 6,279 | $32.3K | 0.00% | +1,943+44.8% | Added |
| Royal Bank of Canada | 6,138 | $31.0K | 0.00% | +4,449+263.4% | Added |
| ORG Partners LLC | 5,270 | $28.9K | 0.00% | +5,270 | New |
| Tower Research Capital LLC (TRC) | 5,157 | $26.5K | 0.00% | −1,906−27.0% | Reduced |
| California State Teachers Retirement System | 4,110 | $21.1K | 0.00% | +132+3.3% | Added |
| Ameritas Investment Partners, Inc. | 3,901 | $20.1K | 0.00% | 00.0% | Unchanged |