Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Prime Medicine, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 105
- +22 vs. Q3 2023
- Shares held
- 48.7M
- −826.1K (−1.7%) vs. Q3 2023
- Total value
- $431.4M
- −$40.8M (−8.6%) vs. Q3 2023
- New holders
- 34
- 26 more added
- Sold out
- 12
- 27 more reduced
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 15 | $0 | 0.00% | +7+87.5% | Added |
| CWM, LLC | 46 | $0 | 0.00% | +46 | New |
| Nisa Investment Advisors, LLC | 24 | $213 | 0.00% | +4+20.0% | Added |
| GAMMA Investing LLC | 118 | $749 | 0.00% | +118 | New |
| Glassman Wealth Services | 103 | $913 | 0.00% | +103 | New |
| Principal Securities, Inc. | 252 | $2.23K | 0.00% | +252 | New |
| Benjamin Edwards Inc | 314 | $3.00K | 0.00% | −7−2.2% | Reduced |
| Daiwa Securities Group Inc. | 398 | $4.00K | 0.00% | +398 | New |
| Fairman Group, LLC | 500 | $4.43K | 0.00% | +500 | New |
| First Horizon Advisors, Inc. | 810 | $7.18K | 0.00% | −221−21.4% | Reduced |
| Sandia Investment Management LP | 1,084 | $9.60K | 0.01% | −8,916−89.2% | Reduced |
| Advisory Services Network, LLC | 1,153 | $10.2K | 0.00% | +1,153 | New |
| Comerica Bank | 1,314 | $11.6K | 0.00% | +535+68.7% | Added |
| Lazard Asset Management LLC | 1,732 | $15.0K | 0.00% | +62+3.7% | Added |
| Metropolitan Life Insurance Co | 2,203 | $19.5K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 3,901 | $34.6K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 4,336 | $38.4K | 0.00% | −188−4.2% | Reduced |
| Chelsea Counsel Co | 5,000 | $44.3K | 0.02% | +4,400+733.3% | Added |
| ORG Partners LLC | 5,270 | $46.7K | 0.01% | 00.0% | Unchanged |
| Amalgamated Bank | 5,613 | $50.0K | 0.00% | −401−6.7% | Reduced |
| California State Teachers Retirement System | 6,511 | $57.7K | 0.00% | −2,218−25.4% | Reduced |
| New York State Common Retirement Fund | 8,440 | $74.8K | 0.00% | −7,876−48.3% | Reduced |
| Brown Brothers Harriman & Co | 10,065 | $89.2K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 10,128 | $90.0K | 0.00% | +10,128 | New |
| Y-Intercept (Hong Kong) Ltd | 10,193 | $90.3K | 0.01% | +10,193 | New |
| Wells Fargo & Company | 10,229 | $90.6K | 0.00% | −21,088−67.3% | Reduced |
| Citigroup Inc | 10,935 | $96.9K | 0.00% | −45,258−80.5% | Reduced |
| China Universal Asset Management Co., Ltd. | 11,258 | $99.7K | 0.02% | +11,258 | New |
| State Board of Administration of Florida Retirement System | 11,420 | $101.2K | 0.00% | 00.0% | Unchanged |
| Amundi | 11,770 | $106.0K | 0.00% | +11,770 | New |
| Gsa Capital Partners LLP | 12,195 | $108.0K | 0.01% | +12,195 | New |
| Royal Bank of Canada | 12,173 | $109.0K | 0.00% | +7,220+145.8% | Added |
| CIBC World Markets Inc. | 12,261 | $109.0K | 0.00% | +12,261 | New |
| ProShare Advisors LLC | 12,756 | $113.0K | 0.00% | +12,756 | New |
| Advisor Group Holdings, Inc. | 13,570 | $120.2K | 0.00% | +5,608+70.4% | Added |
| Red Lighthouse Investment Management, LLC | 14,950 | $132.5K | 0.06% | 00.0% | Unchanged |
| Clarius Group, LLC | 16,080 | $142.5K | 0.01% | 00.0% | Unchanged |
| Voya Investment Management LLC | 16,160 | $143.2K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 17,100 | $151.0K | 0.00% | +17,100 | New |
| Principal Financial Group Inc | 17,890 | $158.5K | 0.00% | −151−0.8% | Reduced |
| American International Group, Inc. | 19,663 | $174.2K | 0.00% | −80−0.4% | Reduced |
| Levin Capital Strategies, L.P. | 20,000 | $177.2K | 0.02% | +20,000 | New |
| Deutsche Bank AG | 20,101 | $178.1K | 0.00% | −454−2.2% | Reduced |
| Vestal Point Capital, LP | 20,306 | $179.9K | 0.02% | +20,306 | New |
| Oppenheimer & Co Inc | 20,598 | $182.5K | 0.00% | −939−4.4% | Reduced |
| HighTower Advisors, LLC | 21,117 | $185.0K | 0.00% | −182−0.9% | Reduced |
| Tower Research Capital LLC (TRC) | 21,011 | $186.2K | 0.00% | +17,483+495.5% | Added |
| MetLife Investment Management | 21,262 | $188.4K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 21,301 | $188.7K | 0.00% | −1,715−7.5% | Reduced |
| PEAK6 Investments LLC | 22,000 | $194.9K | 0.01% | +22,000 | New |
| Envestnet Asset Management Inc | 22,370 | $198.2K | 0.00% | +5,754+34.6% | Added |
| Trexquant Investment LP | 26,983 | $239.1K | 0.01% | +26,983 | New |
| Green Alpha Advisors, LLC | 29,538 | $261.7K | 0.19% | −8,277−21.9% | Reduced |
| UBS Group AG | 31,412 | $278.3K | 0.00% | −12,360−28.2% | Reduced |
| Brandywine Managers, LLC | 32,977 | $292.2K | 0.32% | 00.0% | Unchanged |
| EntryPoint Capital, LLC | 35,235 | $312.2K | 0.30% | +35,235 | New |
| Alliancebernstein L.P. | 37,360 | $331.0K | 0.00% | +5,520+17.3% | Added |
| Royce & Associates LP | 39,837 | $353.0K | 0.00% | +39,837 | New |
| JPMorgan Chase & Co | 45,519 | $403.3K | 0.00% | +18,505+68.5% | Added |
| Two Sigma Advisers, LP | 46,000 | $407.6K | 0.00% | +46,000 | New |
| Susquehanna International Group, LLP | 46,585 | $412.7K | 0.00% | +46,585 | New |
| Bank of Montreal | 45,000 | $430.2K | 0.00% | +45,000 | New |
| Rhumbline Advisers | 50,858 | $450.6K | 0.00% | −101−0.2% | Reduced |
| Goldman Sachs Group Inc | 51,149 | $453.2K | 0.00% | −7,762−13.2% | Reduced |
| TD Asset Management Inc | 52,742 | $467.3K | 0.00% | −51,800−49.5% | Reduced |
| Renaissance Technologies LLC | 53,292 | $472.0K | 0.00% | +53,292 | New |
| Barclays PLC | 54,235 | $480.5K | 0.00% | −10,905−16.7% | Reduced |
| Jane Street Group, LLC | 55,219 | $489.2K | 0.00% | +55,219 | New |
| HRT Financial LP | 59,116 | $523.0K | 0.00% | +59,116 | New |
| Manufacturers Life Insurance Company, The | 64,547 | $571.9K | 0.00% | −113−0.2% | Reduced |
| Walleye Capital LLC | 68,306 | $605.2K | 0.01% | +57,606+538.4% | Added |
| Squarepoint Ops LLC | 71,523 | $633.7K | 0.00% | +56,033+361.7% | Added |
| Sphera Funds Management Ltd. | 73,980 | $655.5K | 0.12% | +73,980 | New |
| TrueMark Investments, LLC | 75,030 | $664.8K | 0.66% | +75,030 | New |
| Nuveen Asset Management, LLC | 108,093 | $957.7K | 0.00% | +1,171+1.1% | Added |
| Bank of New York Mellon Corp | 114,246 | $1.01M | 0.00% | −1,143−1.0% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 116,887 | $1.04M | 0.02% | +116,887 | New |
| Woodline Partners LP | 120,060 | $1.06M | 0.01% | +120,060 | New |
| Millennium Management LLC | 134,544 | $1.19M | 0.00% | +134,544 | New |
| Vestmark Advisory Solutions, Inc. | 144,288 | $1.28M | 0.06% | +144,288 | New |
| FIL Ltd | 146,942 | $1.30M | 0.00% | −1,658,616−91.9% | Reduced |
| Ensign Peak Advisors, Inc | 150,000 | $1.33M | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 211,734 | $1.88M | 0.00% | +168,943+394.8% | Added |
| Two Sigma Investments, LP | 268,362 | $2.38M | 0.01% | +175,369+188.6% | Added |
| Charles Schwab Investment Management Inc | 296,188 | $2.62M | 0.00% | +3,618+1.2% | Added |
| Northern Trust Corp | 344,927 | $3.06M | 0.00% | +11,969+3.6% | Added |
| Bollard Group LLC | 361,136 | $3.20M | 0.11% | +361,136 | New |
| Casdin Capital, LLC | 367,175 | $3.25M | 0.32% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 470,304 | $4.17M | 0.65% | 00.0% | Unchanged |
| Bank of America Corp | 470,596 | $4.17M | 0.00% | +167,954+55.5% | Added |
| Greenwich Wealth Management LLC | 513,001 | $4.54M | 0.45% | +73,980+16.9% | Added |
| State Street Corp | 759,758 | $6.73M | 0.00% | −926,243−54.9% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 885,314 | $7.84M | 0.14% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 887,503 | $7.86M | 0.00% | +40,866+4.8% | Added |
| Baker Bros. Advisors LP | 1,028,466 | $9.11M | 0.10% | 00.0% | Unchanged |
| Redmile Group, LLC | 1,324,350 | $11.7M | 0.42% | 00.0% | Unchanged |
| MWG Management Limited | 1,792,210 | $15.9M | 13.36% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 2,221,159 | $19.7M | 0.00% | +47,788+2.2% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 3,138,270 | $27.8M | 0.16% | +515,841+19.7% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 3,519,029 | $31.2M | 0.02% | −115,819−3.2% | Reduced |