Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 121
- −4 vs. Q1 2025
- Shares held
- 58.7M
- −1.70M (−2.8%) vs. Q1 2025
- Total value
- $145.0M
- +$24.6M (+20.4%) vs. Q1 2025
- New holders
- 29
- 36 more added
- Sold out
- 33
- 35 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 31 | $0 | 0.00% | −2−6.1% | Reduced |
| IFP Advisors, Inc | 8 | $20 | 0.00% | −16−66.7% | Reduced |
| Farther Finance Advisors, LLC | 26 | $64 | 0.00% | −10,737−99.8% | Reduced |
| True Wealth Design, LLC | 115 | $285 | 0.00% | +65+130.0% | Added |
| Advisor Group Holdings, Inc. | 128 | $315 | 0.00% | −36−22.0% | Reduced |
| Larson Financial Group LLC | 200 | $494 | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 210 | $519 | 0.00% | +210 | New |
| Principal Securities, Inc. | 280 | $692 | 0.00% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 285 | $700 | 0.00% | +285 | New |
| Fortitude Family Office, LLC | 296 | $731 | 0.00% | +296 | New |
| The PNC Financial Services Group, Inc. | 319 | $788 | 0.00% | −5−1.5% | Reduced |
| Rothschild Investment LLC | 345 | $852 | 0.00% | +30+9.5% | Added |
| Daiwa Securities Group Inc. | 398 | $1.00K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 482 | $1.19K | 0.00% | +430+826.9% | Added |
| Fairman Group, LLC | 500 | $1.24K | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 615 | $1.52K | 0.00% | +615 | New |
| SBI Securities Co., Ltd. | 727 | $1.80K | 0.00% | +153+26.7% | Added |
| Leonteq Securities AG | 915 | $2.26K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 1,000 | $2.47K | 0.00% | −1,649−62.2% | Reduced |
| EverSource Wealth Advisors, LLC | 1,362 | $3.36K | 0.00% | +350+34.6% | Added |
| Raymond James Financial Inc | 1,564 | $3.86K | 0.00% | +1,564 | New |
| Sterling Capital Management LLC | 1,576 | $3.89K | 0.00% | +1,518+2,617.2% | Added |
| Amalgamated Bank | 1,957 | $5.00K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 3,358 | $8.29K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 3,901 | $9.63K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 4,236 | $10.5K | 0.00% | +3,921+1,244.8% | Added |
| Legal & General Group Plc | 4,899 | $12.1K | 0.00% | −1,016−17.2% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 5,072 | $12.5K | 0.00% | +683+15.6% | Added |
| Royal Bank of Canada | 5,145 | $13.0K | 0.00% | +3,505+213.7% | Added |
| New York State Common Retirement Fund | 8,434 | $20.8K | 0.00% | 00.0% | Unchanged |
| Fogel Capital Management, Inc. | 10,000 | $24.7K | 0.01% | +10,000 | New |
| Creative Planning | 10,145 | $25.1K | 0.00% | +10,145 | New |
| Eqis Capital Management, Inc. | 10,432 | $25.8K | 0.00% | +10,432 | New |
| State Board of Administration of Florida Retirement System | 11,420 | $28.2K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 12,246 | $30.2K | 0.00% | +2,337+23.6% | Added |
| R Squared Ltd | 12,519 | $30.9K | 0.02% | +12,519 | New |
| Virtu Financial LLC | 12,545 | $31.0K | 0.00% | +12,545 | New |
| JTC Employer Solutions Trusteee Ltd | 13,249 | $33.0K | 0.00% | +13,249 | New |
| Invesco Ltd. | 13,662 | $33.7K | 0.00% | −1,174−7.9% | Reduced |
| CIBC World Markets Inc. | 14,326 | $35.4K | 0.00% | −2,689−15.8% | Reduced |
| Commonwealth Equity Services, LLC | 14,942 | $37.0K | 0.00% | +14,942 | New |
| Prime Capital Investment Advisors, LLC | 16,031 | $39.6K | 0.00% | −8,230−33.9% | Reduced |
| Clarius Group, LLC | 16,080 | $39.7K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 16,871 | $41.7K | 0.00% | −1,323−7.3% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 17,092 | $42.2K | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 17,222 | $42.5K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 20,979 | $51.8K | 0.00% | −3,945−15.8% | Reduced |
| Federation des caisses Desjardins du Quebec | 21,200 | $52.4K | 0.00% | +21,200 | New |
| HighTower Advisors, LLC | 21,354 | $52.7K | 0.00% | −292−1.3% | Reduced |
| TD Asset Management Inc | 22,910 | $56.6K | 0.00% | −23,524−50.7% | Reduced |
| JustInvest LLC | 23,191 | $57.3K | 0.00% | +7,954+52.2% | Added |
| Kingsview Wealth Management, LLC | 25,000 | $61.8K | 0.00% | +25,000 | New |
| China Universal Asset Management Co., Ltd. | 26,370 | $65.1K | 0.01% | +61+0.2% | Added |
| BNP Paribas Arbitrage, SA | 26,735 | $66.0K | 0.00% | −4,587−14.6% | Reduced |
| Jane Street Group, LLC | 27,145 | $67.0K | 0.00% | +27,145 | New |
| SG Americas Securities, LLC | 27,919 | $69.0K | 0.00% | −23,537−45.7% | Reduced |
| Intech Investment Management LLC | 30,810 | $76.1K | 0.00% | −24,136−43.9% | Reduced |
| Crestwood Advisors Group LLC | 31,687 | $78.3K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Advisory Services, LLC | 26,007 | $80.9K | 0.00% | +13,777+112.6% | Added |
| JPMorgan Chase & Co | 33,035 | $81.6K | 0.00% | −2,628−7.4% | Reduced |
| Davy Global Fund Management Ltd | 33,660 | $83.1K | 0.01% | −56,210−62.5% | Reduced |
| Citigroup Inc | 34,759 | $85.9K | 0.00% | −7,543−17.8% | Reduced |
| CWM, LLC | 35,761 | $88.0K | 0.00% | +15,295+74.7% | Added |
| Squarepoint Ops LLC | 35,826 | $88.5K | 0.00% | +35,826 | New |
| Ieq Capital, LLC | 35,830 | $88.5K | 0.00% | +948+2.7% | Added |
| Axq Capital, LP | 37,587 | $92.8K | 0.03% | +37,587 | New |
| Jaffetilchin Investment Partners, LLC | 37,744 | $93.2K | 0.01% | +37,744 | New |
| MetLife Investment Management | 39,014 | $96.4K | 0.00% | +39,014 | New |
| Prelude Capital Management, LLC | 41,288 | $102.0K | 0.01% | +41,288 | New |
| HRT Financial LP | 64,167 | $158.0K | 0.00% | +64,167 | New |
| Price T Rowe Associates Inc | 65,320 | $162.0K | 0.00% | −1,501,872−95.8% | Reduced |
| Mutual Advisors, LLC | 45,200 | $190.3K | 0.00% | +45,200 | New |
| Green Alpha Advisors, LLC | 78,994 | $195.1K | 0.19% | −4,473−5.4% | Reduced |
| Rhumbline Advisers | 97,972 | $242.0K | 0.00% | +16,072+19.6% | Added |
| National Bank of Canada | 98,807 | $244.0K | 0.00% | +98,807 | New |
| Wells Fargo & Company | 101,151 | $249.8K | 0.00% | +10,332+11.4% | Added |
| Diametric Capital, LP | 105,530 | $260.7K | 0.14% | +105,530 | New |
| Barclays PLC | 114,802 | $283.6K | 0.00% | +43,378+60.7% | Added |
| FIL Ltd | 117,270 | $289.7K | 0.00% | −3,747−3.1% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 119,856 | $296.0K | 0.00% | +85,938+253.4% | Added |
| Deutsche Bank AG | 125,445 | $309.8K | 0.00% | −1,401−1.1% | Reduced |
| XTX Topco Ltd | 133,490 | $329.7K | 0.01% | +133,490 | New |
| Levin Capital Strategies, L.P. | 140,000 | $345.8K | 0.03% | +105,000+300.0% | Added |
| Bank of America Corp | 144,511 | $356.9K | 0.00% | +31,585+28.0% | Added |
| Millennium Management LLC | 147,996 | $365.6K | 0.00% | −1,631,949−91.7% | Reduced |
| Bank of New York Mellon Corp | 162,052 | $400.3K | 0.00% | +6,060+3.9% | Added |
| Alliancebernstein L.P. | 167,420 | $413.5K | 0.00% | +91,420+120.3% | Added |
| Palumbo Wealth Management LLC | 183,358 | $452.9K | 0.14% | +87,896+92.1% | Added |
| Simplex Trading, LLC | 193,615 | $478.0K | 0.01% | +185,239+2,211.5% | Added |
| UBS Group AG | 195,327 | $482.5K | 0.00% | +77,647+66.0% | Added |
| Goldman Sachs Group Inc | 207,008 | $511.3K | 0.00% | −44,391−17.7% | Reduced |
| Nuveen, LLC | 207,894 | $513.5K | 0.00% | +148,492+250.0% | Added |
| Chelsea Counsel Co | 208,210 | $514.3K | 0.26% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 214,800 | $530.6K | 0.01% | +214,800 | New |
| Renaissance Technologies LLC | 223,400 | $551.8K | 0.00% | −224,200−50.1% | Reduced |
| Two Sigma Investments, LP | 258,423 | $638.3K | 0.00% | −347−0.1% | Reduced |
| Bollard Group LLC | 361,136 | $892.0K | 0.02% | 00.0% | Unchanged |
| Fred Alger Management, LLC | 383,194 | $946.5K | 0.00% | +383,194 | New |
| AQR Capital Management LLC | 424,355 | $1.05M | 0.00% | +180,560+74.1% | Added |
| Susquehanna International Group, LLP | 482,728 | $1.19M | 0.00% | +340,109+238.5% | Added |