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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

Q2 2026 vs. Q1 2026

How the institutions holding Prime Medicine, Inc. changed between Q1 2026 and Q2 2026.

All holders in Q2 2026All holders in Q1 2026

13F holders of PRME: Q1 2026 compared with Q2 2026
MeasureQ1 2026Of which not filed for Q2 2026Q2 2026Change
Holders1924187−1
Shares98.6M98.5K106.6M+8.18M (+8.3%)
Value$342.6M$341.6K$393.5M+$51.3M (+15.0%)

4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (22)

Institutions that held Prime Medicine, Inc. at the end of Q2 2026 but not at the end of Q1 2026.

Institutions new to PRME in Q2 2026
InstitutionSharesValue% of portfolio
Jump Financial, LLC1,240,429$4.58M0.04%
Point72 Asset Management, L.P.533,553$1.97M0.00%
Millennium Management LLC427,097$1.58M0.00%
Jain Global LLC215,218$794.2K0.01%
Jupiter Asset Management Ltd209,490$773.0K0.00%
PEAK6 LLC208,057$767.7K0.02%
ExodusPoint Capital Management, LP118,464$437.1K0.00%
Milestone Asset Management, LLC100,035$369.1K0.06%
Jupiter Topco LLC60,900$224.4K0.00%
SG Americas Securities, LLC58,922$217.0K0.00%
Schonfeld Strategic Advisors LLC20,189$74.5K0.00%
CIBC World Markets Inc.18,662$68.9K0.00%
Brevan Howard Capital Management LP12,910$47.6K0.00%
State of Wisconsin Investment Board12,681$46.8K0.00%
Syon Capital LLC11,077$40.9K0.00%
Pacer Advisors, Inc.2,426$9.00K0.00%
Quarry LP540$1.99K0.00%
Eastern Bank134$4940.00%
Sachetta, LLC100$3690.00%
Natixis45$1660.00%
Clearstead Advisors, LLC9$340.00%
Wealth Enhancement Trust Services, Inc.3$110.00%

Sold out (23)

Institutions that held Prime Medicine, Inc. at the end of Q1 2026 and filed for Q2 2026 without it.

Not filed for Q2 2026 yet (4)

Institutions that held Prime Medicine, Inc. at the end of Q1 2026 and haven't filed a 13F for Q2 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding PRME in Q1 2026 that haven't filed for Q2 2026
InstitutionShares, Q1 2026Value, Q1 2026
Janus Henderson Group PLC60,900$211.6K
CWM, LLC33,811$117.7K
Financial Connections Group, Inc.3,712$12.0K
Sunbelt Securities, Inc.80$278