Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 187
- −1 vs. Q1 2026
- Shares held
- 106.6M
- +8.18M (+8.3%) vs. Q1 2026
- Total value
- $393.5M
- +$51.3M (+15.0%) vs. Q1 2026
- New holders
- 22
- 64 more added
- Sold out
- 23
- 67 more reduced
4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Oppenheimer & Co Inc | 29,650 | $109.4K | 0.00% | −4,006−11.9% | Reduced |
| Raymond James Financial Inc | 29,184 | $107.7K | 0.00% | +17,140+142.3% | Added |
| SEI Investments Co | 29,183 | $107.7K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 28,745 | $106.1K | 0.01% | −3,288−10.3% | Reduced |
| Arizona State Retirement System | 28,646 | $105.7K | 0.00% | +3,855+15.5% | Added |
| Envestnet Asset Management Inc | 28,278 | $104.3K | 0.00% | −762−2.6% | Reduced |
| Manufacturers Life Insurance Company, The | 27,353 | $100.9K | 0.00% | −1,519−5.3% | Reduced |
| Vanguard Investments Australia, Ltd. | 26,124 | $96.4K | 0.00% | 00.0% | Unchanged |
| Blue Bell Private Wealth Management, LLC | 25,830 | $95.3K | 0.01% | −1,185−4.4% | Reduced |
| Mariner, LLC | 25,389 | $93.7K | 0.00% | −53,009−67.6% | Reduced |
| Abacus Planning Group, Inc. | 25,188 | $92.9K | 0.01% | 00.0% | Unchanged |
| Intech Investment Management LLC | 24,363 | $89.9K | 0.00% | −6,175−20.2% | Reduced |
| Creative Planning | 21,295 | $78.6K | 0.00% | −6,951−24.6% | Reduced |
| Magnetar Financial LLC | 21,174 | $78.1K | 0.00% | +5,390+34.1% | Added |
| E Fund Management Co., Ltd. | 20,484 | $75.6K | 0.00% | −6,615−24.4% | Reduced |
| Schonfeld Strategic Advisors LLC | 20,189 | $74.5K | 0.00% | +20,189 | New |
| Voya Investment Management LLC | 20,138 | $74.3K | 0.00% | +2,793+16.1% | Added |
| JustInvest LLC | 20,083 | $74.1K | 0.00% | −1,871−8.5% | Reduced |
| Shelton Wealth Management, LLC | 19,105 | $70.5K | 0.03% | −961−4.8% | Reduced |
| CIBC World Markets Inc. | 18,662 | $68.9K | 0.00% | +18,662 | New |
| Graham Capital Management, L.P. | 18,516 | $68.3K | 0.00% | +2,501+15.6% | Added |
| KLP Kapitalforvaltning AS | 18,500 | $68.3K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 18,243 | $67.3K | 0.00% | −4,725−20.6% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,225 | $67.3K | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 16,427 | $61.0K | 0.00% | +4,090+33.2% | Added |
| Ieq Capital, LLC | 16,503 | $60.9K | 0.00% | −57,510−77.7% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 15,096 | $57.1K | 0.00% | −22,585−59.9% | Reduced |
| Levin Capital Strategies, L.P. | 15,000 | $55.4K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 14,755 | $54.4K | 0.00% | 00.0% | Unchanged |
| Thompson Davis & Co., Inc. | 14,590 | $53.8K | 0.03% | −2,650−15.4% | Reduced |
| Sanctuary Advisors, LLC | 13,400 | $49.4K | 0.00% | −494−3.6% | Reduced |
| JTC Employer Solutions Trusteee Ltd | 13,249 | $49.0K | 0.00% | 00.0% | Unchanged |
| DRW Securities, LLC | 13,106 | $48.4K | 0.00% | −27,858−68.0% | Reduced |
| Prime Capital Investment Advisors, LLC | 12,945 | $47.8K | 0.00% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 12,910 | $47.6K | 0.00% | +12,910 | New |
| State of Wisconsin Investment Board | 12,681 | $46.8K | 0.00% | +12,681 | New |
| Pictet Asset Management Holding SA | 12,107 | $44.7K | 0.00% | 00.0% | Unchanged |
| Sequoia Financial Advisors, LLC | 11,686 | $43.1K | 0.00% | +13+0.1% | Added |
| Teacher Retirement System of Texas | 11,440 | $42.2K | 0.00% | +382+3.5% | Added |
| Wealthfront Advisers LLC | 11,301 | $41.7K | 0.00% | +922+8.9% | Added |
| Syon Capital LLC | 11,077 | $40.9K | 0.00% | +11,077 | New |
| Victory Capital Management Inc | 10,979 | $40.5K | 0.00% | +162+1.5% | Added |
| Benjamin Edwards Inc | 10,329 | $38.1K | 0.00% | −3,523−25.4% | Reduced |
| Kingsview Wealth Management, LLC | 10,000 | $36.9K | 0.00% | −25,000−71.4% | Reduced |
| Forum Financial Management, LP | 10,000 | $36.9K | 0.00% | 00.0% | Unchanged |
| NBC Securities, Inc. | 10,000 | $36.9K | 0.00% | +5,000+100.0% | Added |
| Federation des caisses Desjardins du Quebec | 9,500 | $35.1K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 9,398 | $34.7K | 0.00% | +5,301+129.4% | Added |
| New York State Common Retirement Fund | 8,434 | $31.1K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 8,407 | $31.0K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 8,078 | $29.8K | 0.00% | −1,337−14.2% | Reduced |
| Tower Research Capital LLC (TRC) | 6,683 | $24.7K | 0.00% | −15,131−69.4% | Reduced |
| Royal Bank of Canada | 5,853 | $22.0K | 0.00% | −3,401−36.8% | Reduced |
| Glen Eagle Advisors, LLC | 5,000 | $18.4K | 0.00% | −5,000−50.0% | Reduced |
| Signaturefd, LLC | 5,000 | $18.4K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 4,544 | $16.8K | 0.00% | −4,802−51.4% | Reduced |
| GF Fund Management Co. Ltd. | 3,822 | $14.1K | 0.00% | −214−5.3% | Reduced |
| Owl Creek Wealth Partners LLC | 2,615 | $9.65K | 0.00% | 00.0% | Unchanged |
| Pacer Advisors, Inc. | 2,426 | $9.00K | 0.00% | +2,426 | New |
| Caitong International Asset Management Co., Ltd | 1,644 | $6.07K | 0.00% | +1,261+329.2% | Added |
| EverSource Wealth Advisors, LLC | 1,376 | $5.08K | 0.00% | −624−31.2% | Reduced |
| Allworth Financial LP | 1,278 | $4.72K | 0.00% | −3,127−71.0% | Reduced |
| GWM Advisors LLC | 1,000 | $3.69K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 961 | $3.55K | 0.00% | +731+317.8% | Added |
| GAMMA Investing LLC | 586 | $2.16K | 0.00% | −61−9.4% | Reduced |
| SBI Securities Co., Ltd. | 580 | $2.14K | 0.00% | +189+48.3% | Added |
| Quarry LP | 540 | $1.99K | 0.00% | +540 | New |
| Sterling Capital Management LLC | 536 | $1.98K | 0.00% | −2,926−84.5% | Reduced |
| Fairman Group, LLC | 500 | $1.84K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 384 | $1.42K | 0.00% | +2+0.5% | Added |
| The PNC Financial Services Group, Inc. | 319 | $1.18K | 0.00% | 00.0% | Unchanged |
| Fortitude Family Office, LLC | 308 | $1.14K | 0.00% | −128−29.4% | Reduced |
| Basecamp Wealth Advisors LLC | 292 | $1.08K | 0.00% | +5+1.7% | Added |
| Parkside Financial Bank & Trust | 285 | $1.05K | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 260 | $959 | 0.00% | −632−70.9% | Reduced |
| Eastern Bank | 134 | $494 | 0.00% | +134 | New |
| Sachetta, LLC | 100 | $369 | 0.00% | +100 | New |
| Harbour Investments, Inc. | 78 | $288 | 0.00% | +4+5.4% | Added |
| Farther Finance Advisors, LLC | 55 | $203 | 0.00% | −99−64.3% | Reduced |
| Newbridge Financial Services Group, Inc. | 45 | $166 | 0.00% | 00.0% | Unchanged |
| Natixis | 45 | $166 | 0.00% | +45 | New |
| National Bank of Canada | 42 | $155 | 0.00% | +32+320.0% | Added |
| Essential Partners LLC | 27 | $100 | 0.00% | −981−97.3% | Reduced |
| IFP Advisors, Inc | 23 | $85 | 0.00% | +21+1,050.0% | Added |
| Clearstead Advisors, LLC | 9 | $34 | 0.00% | +9 | New |
| Wealth Enhancement Trust Services, Inc. | 3 | $11 | 0.00% | +3 | New |
| Covestor Ltd | 105 | $0 | 0.00% | +74+238.7% | Added |
| Elevate Capital Advisors, LLC | 0 | $0 | 0.00% | −151,069−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −61,546−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −54,230−100.0% | Sold out |
| VARCOV Co. | 0 | $0 | 0.00% | −41,964−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −36,742−100.0% | Sold out |
| Transcend Wealth Collective, LLC | 0 | $0 | 0.00% | −30,070−100.0% | Sold out |
| Turtle Creek Wealth Advisors, LLC | 0 | $0 | 0.00% | −25,000−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −24,823−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −24,766−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −17,931−100.0% | Sold out |
| Martingale Asset Management L P | 0 | $0 | 0.00% | −14,848−100.0% | Sold out |
| Sterling Investment Advisors, Ltd. | 0 | $0 | 0.00% | −13,400−100.0% | Sold out |
| Mercer Global Advisors Inc | 0 | $0 | 0.00% | −12,305−100.0% | Sold out |