Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 187
- −1 vs. Q1 2026
- Shares held
- 106.6M
- +8.18M (+8.3%) vs. Q1 2026
- Total value
- $393.5M
- +$51.3M (+15.0%) vs. Q1 2026
- New holders
- 22
- 64 more added
- Sold out
- 23
- 67 more reduced
4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 105 | $0 | 0.00% | +74+238.7% | Added |
| Wealth Enhancement Trust Services, Inc. | 3 | $11 | 0.00% | +3 | New |
| Clearstead Advisors, LLC | 9 | $34 | 0.00% | +9 | New |
| IFP Advisors, Inc | 23 | $85 | 0.00% | +21+1,050.0% | Added |
| Essential Partners LLC | 27 | $100 | 0.00% | −981−97.3% | Reduced |
| National Bank of Canada | 42 | $155 | 0.00% | +32+320.0% | Added |
| Newbridge Financial Services Group, Inc. | 45 | $166 | 0.00% | 00.0% | Unchanged |
| Natixis | 45 | $166 | 0.00% | +45 | New |
| Farther Finance Advisors, LLC | 55 | $203 | 0.00% | −99−64.3% | Reduced |
| Harbour Investments, Inc. | 78 | $288 | 0.00% | +4+5.4% | Added |
| Sachetta, LLC | 100 | $369 | 0.00% | +100 | New |
| Eastern Bank | 134 | $494 | 0.00% | +134 | New |
| Optiver Holding B.V. | 260 | $959 | 0.00% | −632−70.9% | Reduced |
| Parkside Financial Bank & Trust | 285 | $1.05K | 0.00% | 00.0% | Unchanged |
| Basecamp Wealth Advisors LLC | 292 | $1.08K | 0.00% | +5+1.7% | Added |
| Fortitude Family Office, LLC | 308 | $1.14K | 0.00% | −128−29.4% | Reduced |
| The PNC Financial Services Group, Inc. | 319 | $1.18K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 384 | $1.42K | 0.00% | +2+0.5% | Added |
| Fairman Group, LLC | 500 | $1.84K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 536 | $1.98K | 0.00% | −2,926−84.5% | Reduced |
| Quarry LP | 540 | $1.99K | 0.00% | +540 | New |
| SBI Securities Co., Ltd. | 580 | $2.14K | 0.00% | +189+48.3% | Added |
| GAMMA Investing LLC | 586 | $2.16K | 0.00% | −61−9.4% | Reduced |
| SRS Capital Advisors, Inc. | 961 | $3.55K | 0.00% | +731+317.8% | Added |
| GWM Advisors LLC | 1,000 | $3.69K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 1,278 | $4.72K | 0.00% | −3,127−71.0% | Reduced |
| EverSource Wealth Advisors, LLC | 1,376 | $5.08K | 0.00% | −624−31.2% | Reduced |
| Caitong International Asset Management Co., Ltd | 1,644 | $6.07K | 0.00% | +1,261+329.2% | Added |
| Pacer Advisors, Inc. | 2,426 | $9.00K | 0.00% | +2,426 | New |
| Owl Creek Wealth Partners LLC | 2,615 | $9.65K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 3,822 | $14.1K | 0.00% | −214−5.3% | Reduced |
| Nisa Investment Advisors, LLC | 4,544 | $16.8K | 0.00% | −4,802−51.4% | Reduced |
| Glen Eagle Advisors, LLC | 5,000 | $18.4K | 0.00% | −5,000−50.0% | Reduced |
| Signaturefd, LLC | 5,000 | $18.4K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 5,853 | $22.0K | 0.00% | −3,401−36.8% | Reduced |
| Tower Research Capital LLC (TRC) | 6,683 | $24.7K | 0.00% | −15,131−69.4% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 8,078 | $29.8K | 0.00% | −1,337−14.2% | Reduced |
| Ameritas Investment Partners, Inc. | 8,407 | $31.0K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 8,434 | $31.1K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 9,398 | $34.7K | 0.00% | +5,301+129.4% | Added |
| Federation des caisses Desjardins du Quebec | 9,500 | $35.1K | 0.00% | 00.0% | Unchanged |
| Kingsview Wealth Management, LLC | 10,000 | $36.9K | 0.00% | −25,000−71.4% | Reduced |
| Forum Financial Management, LP | 10,000 | $36.9K | 0.00% | 00.0% | Unchanged |
| NBC Securities, Inc. | 10,000 | $36.9K | 0.00% | +5,000+100.0% | Added |
| Benjamin Edwards Inc | 10,329 | $38.1K | 0.00% | −3,523−25.4% | Reduced |
| Victory Capital Management Inc | 10,979 | $40.5K | 0.00% | +162+1.5% | Added |
| Syon Capital LLC | 11,077 | $40.9K | 0.00% | +11,077 | New |
| Wealthfront Advisers LLC | 11,301 | $41.7K | 0.00% | +922+8.9% | Added |
| Teacher Retirement System of Texas | 11,440 | $42.2K | 0.00% | +382+3.5% | Added |
| Sequoia Financial Advisors, LLC | 11,686 | $43.1K | 0.00% | +13+0.1% | Added |
| Pictet Asset Management Holding SA | 12,107 | $44.7K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 12,681 | $46.8K | 0.00% | +12,681 | New |
| Brevan Howard Capital Management LP | 12,910 | $47.6K | 0.00% | +12,910 | New |
| Prime Capital Investment Advisors, LLC | 12,945 | $47.8K | 0.00% | 00.0% | Unchanged |
| DRW Securities, LLC | 13,106 | $48.4K | 0.00% | −27,858−68.0% | Reduced |
| JTC Employer Solutions Trusteee Ltd | 13,249 | $49.0K | 0.00% | 00.0% | Unchanged |
| Sanctuary Advisors, LLC | 13,400 | $49.4K | 0.00% | −494−3.6% | Reduced |
| Thompson Davis & Co., Inc. | 14,590 | $53.8K | 0.03% | −2,650−15.4% | Reduced |
| Prudential Financial Inc | 14,755 | $54.4K | 0.00% | 00.0% | Unchanged |
| Levin Capital Strategies, L.P. | 15,000 | $55.4K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Advisory Services, LLC | 15,096 | $57.1K | 0.00% | −22,585−59.9% | Reduced |
| Ieq Capital, LLC | 16,503 | $60.9K | 0.00% | −57,510−77.7% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 16,427 | $61.0K | 0.00% | +4,090+33.2% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,225 | $67.3K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 18,243 | $67.3K | 0.00% | −4,725−20.6% | Reduced |
| KLP Kapitalforvaltning AS | 18,500 | $68.3K | 0.00% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 18,516 | $68.3K | 0.00% | +2,501+15.6% | Added |
| CIBC World Markets Inc. | 18,662 | $68.9K | 0.00% | +18,662 | New |
| Shelton Wealth Management, LLC | 19,105 | $70.5K | 0.03% | −961−4.8% | Reduced |
| JustInvest LLC | 20,083 | $74.1K | 0.00% | −1,871−8.5% | Reduced |
| Voya Investment Management LLC | 20,138 | $74.3K | 0.00% | +2,793+16.1% | Added |
| Schonfeld Strategic Advisors LLC | 20,189 | $74.5K | 0.00% | +20,189 | New |
| E Fund Management Co., Ltd. | 20,484 | $75.6K | 0.00% | −6,615−24.4% | Reduced |
| Magnetar Financial LLC | 21,174 | $78.1K | 0.00% | +5,390+34.1% | Added |
| Creative Planning | 21,295 | $78.6K | 0.00% | −6,951−24.6% | Reduced |
| Intech Investment Management LLC | 24,363 | $89.9K | 0.00% | −6,175−20.2% | Reduced |
| Abacus Planning Group, Inc. | 25,188 | $92.9K | 0.01% | 00.0% | Unchanged |
| Mariner, LLC | 25,389 | $93.7K | 0.00% | −53,009−67.6% | Reduced |
| Blue Bell Private Wealth Management, LLC | 25,830 | $95.3K | 0.01% | −1,185−4.4% | Reduced |
| Vanguard Investments Australia, Ltd. | 26,124 | $96.4K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 27,353 | $100.9K | 0.00% | −1,519−5.3% | Reduced |
| Envestnet Asset Management Inc | 28,278 | $104.3K | 0.00% | −762−2.6% | Reduced |
| Arizona State Retirement System | 28,646 | $105.7K | 0.00% | +3,855+15.5% | Added |
| China Universal Asset Management Co., Ltd. | 28,745 | $106.1K | 0.01% | −3,288−10.3% | Reduced |
| SEI Investments Co | 29,183 | $107.7K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 29,184 | $107.7K | 0.00% | +17,140+142.3% | Added |
| Oppenheimer & Co Inc | 29,650 | $109.4K | 0.00% | −4,006−11.9% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 30,751 | $113.5K | 0.00% | 00.0% | Unchanged |
| Crestwood Advisors Group LLC | 32,041 | $118.2K | 0.00% | −333−1.0% | Reduced |
| State of New Jersey Common Pension Fund D | 33,569 | $123.9K | 0.00% | +2,724+8.8% | Added |
| Jones Financial Companies LLLP | 40,867 | $140.2K | 0.00% | +560+1.4% | Added |
| CI Private Wealth, LLC | 39,078 | $144.2K | 0.00% | −2,143−5.2% | Reduced |
| IvyRock Asset Management (HK) Ltd | 41,800 | $154.2K | 0.09% | 00.0% | Unchanged |
| Quadrature Capital Ltd | 43,663 | $161.1K | 0.00% | −3,230−6.9% | Reduced |
| Vanguard Global Advisers, LLC | 44,269 | $163.4K | 0.00% | 00.0% | Unchanged |
| Mutual Advisors, LLC | 45,000 | $166.1K | 0.00% | −200−0.4% | Reduced |
| Ameriprise Financial Inc | 49,941 | $184.3K | 0.00% | +357+0.7% | Added |
| Russell Investments Group, Ltd. | 50,994 | $188.2K | 0.00% | −13,279−20.7% | Reduced |
| MetLife Investment Management | 56,192 | $207.3K | 0.00% | +11,984+27.1% | Added |
| Wiley Bros.-Aintree Capital, LLC | 57,460 | $210.6K | 0.00% | −2,010−3.4% | Reduced |