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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
291
+48 vs. Q4 2025
Shares held
31.8M
+3.79M (+13.5%) vs. Q4 2025
Total value
$10.2B
+$1.98B (+24.0%) vs. Q4 2025
New holders
80
121 more added
Sold out
32
68 more reduced

7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 291 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ1 2026: $10.2B
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2025.

Institutions holding PRAX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Tudor Investment Corp Et Al0$00.00%−16,009−100.0%Sold out
Eagle Health Investments LP0$00.00%−14,951−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−10,140−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−4,587−100.0%Sold out
Walleye Capital LLC0$00.00%−3,587−100.0%Sold out
Public Sector Pension Investment Board0$00.00%−3,297−100.0%Sold out
Seven Fleet Capital Management LP0$00.00%−2,700−100.0%Sold out
Skopos Labs, Inc.0$00.00%−2,179−100.0%Sold out
Quinn Opportunity Partners LLC0$00.00%−2,000−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−1,856−100.0%Sold out
Total Clarity Wealth Management, Inc.0$00.00%−1,820−100.0%Sold out
Mackenzie Financial Corp0$00.00%−1,399−100.0%Sold out
Kestra Advisory Services, LLC0$00.00%−1,180−100.0%Sold out
Opal Capital LLC0$00.00%−996−100.0%Sold out
Quest Partners LLC0$00.00%−1,075−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−887−100.0%Sold out
Sanctuary Advisors, LLC0$00.00%−681−100.0%Sold out
Danske Bank A/S0$00.00%−200−100.0%Sold out
Havemeyer Place LP0$00.00%−74−100.0%Sold out
Aspect Partners, LLC0$00.00%−47−100.0%Sold out
Bellevue Asset Management, LLC0$00.00%−6−100.0%Sold out
MidFirst Bank0$00.00%−5−100.0%Sold out
Marquette Asset Management, LLC0$00.00%−2−100.0%Sold out
Vanguard Group Inc––––Not filed
Norges Bank––––Not filed
CIBC World Markets Corp––––Not filed
Global Retirement Partners, LLC––––Not filed
Comerica Bank––––Not filed
CIBC Private Wealth Group, LLC––––Not filed
ORG Partners LLC––––Not filed