Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Opko Health, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 236
- +21 vs. Q4 2025
- Shares held
- 201.2M
- +34.3M (+20.5%) vs. Q4 2025
- Total value
- $229.4M
- +$19.5M (+9.3%) vs. Q4 2025
- New holders
- 44
- 59 more added
- Sold out
- 23
- 62 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Apella Capital, LLC | 27,021 | $33.5K | 0.00% | +27,021 | New |
| Wellington Grp LLC | 30,000 | $34.2K | 0.01% | −30,000−50.0% | Reduced |
| IPG Investment Advisors LLC | 30,000 | $34.2K | 0.01% | 00.0% | Unchanged |
| EP Wealth Advisors, LLC | 30,170 | $34.4K | 0.00% | +724+2.5% | Added |
| Russell Investments Group, Ltd. | 31,816 | $36.3K | 0.00% | −2,874−8.3% | Reduced |
| Ameritas Investment Partners, Inc. | 31,889 | $36.4K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 31,900 | $36.4K | 0.00% | 00.0% | Unchanged |
| Operose Advisors LLC | 32,000 | $36.5K | 0.01% | 00.0% | Unchanged |
| Warren Averett Asset Management, LLC | 32,556 | $37.1K | 0.00% | −2,171−6.3% | Reduced |
| Raymond James Financial Inc | 32,624 | $37.2K | 0.00% | −6,120−15.8% | Reduced |
| Abel Hall, LLC | 33,271 | $37.9K | 0.01% | +33,271 | New |
| HighTower Advisors, LLC | 33,311 | $38.0K | 0.00% | −4,142−11.1% | Reduced |
| Citigroup Inc | 33,676 | $38.4K | 0.00% | +17,134+103.6% | Added |
| RSM US Wealth Management LLC | 33,757 | $38.5K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 34,714 | $39.6K | 0.00% | +8,277+31.3% | Added |
| The PNC Financial Services Group, Inc. | 37,000 | $42.2K | 0.00% | 00.0% | Unchanged |
| Xponance, Inc. | 37,294 | $42.5K | 0.00% | +4,933+15.2% | Added |
| Brighton Jones LLC | 37,950 | $43.3K | 0.00% | +37,950 | New |
| Mariner, LLC | 39,346 | $44.8K | 0.00% | −2,879−6.8% | Reduced |
| Hollencrest Capital Management | 40,000 | $45.6K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 40,306 | $45.9K | 0.00% | +186+0.5% | Added |
| Group One Trading, L.P. | 40,662 | $46.4K | 0.00% | +40,662 | New |
| FMR LLC | 41,343 | $47.1K | 0.00% | +27,256+193.5% | Added |
| Victory Capital Management Inc | 44,268 | $50.5K | 0.00% | −757−1.7% | Reduced |
| LGL Partners, LLC | 44,507 | $50.7K | 0.02% | +44,507 | New |
| Brevan Howard Capital Management LP | 45,919 | $52.3K | 0.00% | −39,429−46.2% | Reduced |
| Advisor Group Holdings, Inc. | 47,667 | $54.3K | 0.00% | −27,648−36.7% | Reduced |
| Farmers National Bank | 50,300 | $57.3K | 0.01% | 00.0% | Unchanged |
| Transcend Wealth Collective, LLC | 51,905 | $59.2K | 0.00% | −836−1.6% | Reduced |
| First Manhattan Co | 52,150 | $59.5K | 0.00% | +400+0.8% | Added |
| Mercer Global Advisors Inc | 52,832 | $60.2K | 0.00% | −6,194−10.5% | Reduced |
| Graham Capital Management, L.P. | 52,859 | $60.3K | 0.00% | −66,795−55.8% | Reduced |
| Great West Life Assurance Co | 54,068 | $62.0K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $62.9K | 0.00% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 55,301 | $63.0K | 0.00% | 00.0% | Unchanged |
| Headlands Technologies LLC | 56,480 | $64.4K | 0.01% | −32,482−36.5% | Reduced |
| Kestra Private Wealth Services, LLC | 58,450 | $66.6K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 59,352 | $67.7K | 0.00% | +189+0.3% | Added |
| Public Employees Retirement Association of Colorado | 61,502 | $70.0K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Advisory Services, LLC | 62,365 | $71.1K | 0.00% | +4,836+8.4% | Added |
| Pictet Asset Management Holding SA | 65,495 | $74.7K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 65,556 | $74.7K | 0.00% | +39,190+148.6% | Added |
| Cascade Financial Partners, LLC | 66,490 | $75.8K | 0.01% | 00.0% | Unchanged |
| Pensionmark Financial Group, LLC | 66,520 | $75.8K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 69,834 | $79.6K | 0.00% | +687+1.0% | Added |
| SG Americas Securities, LLC | 87,846 | $100.0K | 0.00% | +33,824+62.6% | Added |
| RPg Family Wealth Advisory, LLC | 88,619 | $101.0K | 0.02% | −10,371−10.5% | Reduced |
| Quadrature Capital Ltd | 88,937 | $101.4K | 0.00% | −2,765−3.0% | Reduced |
| BNP Paribas Arbitrage, SA | 89,732 | $102.3K | 0.00% | −701−0.8% | Reduced |
| HRT Financial LP | 90,759 | $103.0K | 0.00% | −584,724−86.6% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 90,279 | $103.0K | 0.00% | +558+0.6% | Added |
| KLP Kapitalforvaltning AS | 90,700 | $103.4K | 0.00% | 00.0% | Unchanged |
| Ieq Capital, LLC | 93,222 | $106.3K | 0.00% | −64,557−40.9% | Reduced |
| Point72 Asset Management, L.P. | 93,335 | $106.4K | 0.00% | +93,335 | New |
| Ameriprise Financial Inc | 96,722 | $110.3K | 0.00% | +480+0.5% | Added |
| 360 Financial, Inc. | 97,300 | $110.9K | 0.03% | +10,000+11.5% | Added |
| Police & Firemen's Retirement System of New Jersey | 102,397 | $116.7K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 109,543 | $124.9K | 0.00% | +109,543 | New |
| Vanguard Investments Australia, Ltd. | 110,958 | $126.5K | 0.00% | +110,958 | New |
| Glenmede Trust Co NA | 112,750 | $128.5K | 0.00% | −733−0.6% | Reduced |
| New York State Common Retirement Fund | 114,301 | $130.3K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 115,978 | $132.2K | 0.00% | +2,144+1.9% | Added |
| Highline Wealth Partners LLC | 116,680 | $133.0K | 0.03% | −10.0% | Reduced |
| Manufacturers Life Insurance Company, The | 122,128 | $139.2K | 0.00% | −107,462−46.8% | Reduced |
| Intech Investment Management LLC | 125,814 | $143.4K | 0.00% | −33,838−21.2% | Reduced |
| Tower Research Capital LLC (TRC) | 128,713 | $146.7K | 0.00% | +119,585+1,310.1% | Added |
| Fifth Third Bancorp | 128,791 | $146.8K | 0.00% | +128,791 | New |
| U.S. Capital Wealth Advisors, LLC | 133,261 | $151.9K | 0.00% | +133,261 | New |
| Barclays PLC | 138,300 | $157.7K | 0.00% | −524,936−79.1% | Reduced |
| Teton Advisors, LLC | 140,000 | $159.6K | 0.11% | 00.0% | Unchanged |
| ProShare Advisors LLC | 140,658 | $160.3K | 0.00% | −15,696−10.0% | Reduced |
| Van Eck Associates Corp | 160,096 | $183.0K | 0.00% | +23,077+16.8% | Added |
| Wells Fargo & Company | 162,609 | $185.4K | 0.00% | −305,909−65.3% | Reduced |
| State of Wyoming | 167,020 | $190.4K | 0.02% | +167,020 | New |
| Two Sigma Investments, LP | 170,000 | $193.8K | 0.00% | −564,747−76.9% | Reduced |
| Gabelli Funds LLC | 170,000 | $193.8K | 0.00% | 00.0% | Unchanged |
| Gamco Investors, Inc. Et Al | 175,000 | $199.5K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 176,260 | $200.9K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 176,985 | $201.8K | 0.00% | +118,924+204.8% | Added |
| Vanguard Global Advisers, LLC | 181,766 | $207.2K | 0.00% | +181,766 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 197,906 | $225.6K | 0.00% | +6,802+3.6% | Added |
| MetLife Investment Management | 204,738 | $233.4K | 0.00% | +29,062+16.5% | Added |
| Janus Henderson Group PLC | 206,314 | $236.2K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 219,994 | $251.0K | 0.00% | −41,026−15.7% | Reduced |
| HSBC Holdings PLC | 238,281 | $272.8K | 0.00% | +238,281 | New |
| Tudor Investment Corp Et Al | 244,821 | $279.1K | 0.00% | 00.0% | Unchanged |
| Vanguard Asset Management, Ltd | 294,013 | $335.2K | 0.00% | +294,013 | New |
| Zazove Associates LLC | 300,000 | $360.0K | 0.02% | +150,000+100.0% | Added |
| EntryPoint Capital, LLC | 342,171 | $390.1K | 0.11% | +33,147+10.7% | Added |
| Legal & General Group Plc | 343,474 | $391.6K | 0.00% | −109,791−24.2% | Reduced |
| Deutsche Bank AG | 370,948 | $422.9K | 0.00% | +45,059+13.8% | Added |
| Susquehanna International Group, LLP | 391,516 | $446.3K | 0.00% | −45,771−10.5% | Reduced |
| Qube Research & Technologies Ltd | 404,358 | $461.0K | 0.00% | +301,595+293.5% | Added |
| Price T Rowe Associates Inc | 404,652 | $462.0K | 0.00% | +37,461+10.2% | Added |
| California State Teachers Retirement System | 414,037 | $472.0K | 0.00% | −3,051−0.7% | Reduced |
| Commonwealth Equity Services, LLC | 430,906 | $491.2K | 0.00% | −210,550−32.8% | Reduced |
| XTX Topco Ltd | 430,966 | $491.3K | 0.01% | +88,209+25.7% | Added |
| Kovack Advisors, Inc. | 459,700 | $524.1K | 0.03% | +459,700 | New |
| Alliancebernstein L.P. | 423,190 | $533.2K | 0.00% | −25,000−5.6% | Reduced |
| JPMorgan Chase & Co | 508,484 | $559.3K | 0.00% | −71,294−12.3% | Reduced |