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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
137
+12 vs. Q2 2024
Shares held
288.6M
+19.6M (+7.3%) vs. Q2 2024
Total value
$453.1M
−$1.27M (−0.3%) vs. Q2 2024
New holders
26
46 more added
Sold out
14
20 more reduced

2 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 137 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ3 2024: $453.1M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q2 2024.

Institutions holding LXRX in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Rhumbline Advisers145,939$229.1K0.00%−6,846−4.5%Reduced
California State Teachers Retirement System150,300$236.0K0.00%+141,981+1,706.7%Added
Deerfield Management Company, L.P. (Series C)156,860$246.3K0.00%+156,860New
Virtus ETF Advisers LLC179,972$282.6K0.13%00.0%Unchanged
Squarepoint Ops LLC188,842$296.5K0.00%+188,842New
Barclays PLC193,873$304.4K0.00%+154,436+391.6%Added
Two Sigma Investments, LP204,879$321.7K0.00%+185,723+969.5%Added
Alliancebernstein L.P.273,041$428.7K0.00%00.0%Unchanged
Bank of New York Mellon Corp314,780$494.2K0.00%−87,128−21.7%Reduced
Swiss National Bank317,500$498.5K0.00%+317,500New
Goldman Sachs Group Inc401,291$630.0K0.00%+27,860+7.5%Added
Morgan Stanley454,977$714.3K0.00%+100,941+28.5%Added
BBR Partners, LLC470,000$737.9K0.06%+200,000+74.1%Added
Knott David M Jr500,000$785.0K0.31%+500,000New
Marshall Wace, LLP574,150$901.4K0.00%−616,298−51.8%Reduced
Hennion & Walsh Asset Management, Inc.731,138$1.15M0.05%+188,239+34.7%Added
Wellington Management Group LLP732,747$1.15M0.00%−5,881−0.8%Reduced
Braidwell LP801,584$1.26M0.04%−7,493,366−90.3%Reduced
Nuveen Asset Management, LLC1,103,840$1.73M0.00%+887,574+410.4%Added
Northern Trust Corp1,144,031$1.80M0.00%+146,503+14.7%Added
Woodline Partners LP1,211,924$1.90M0.02%+1,211,924New
Point72 Asset Management, L.P.1,230,050$1.93M0.01%−2,891,141−70.2%Reduced
Millennium Management LLC1,398,876$2.20M0.00%+801,555+134.2%Added
Charles Schwab Investment Management Inc1,417,295$2.23M0.00%+58,147+4.3%Added
Pinnacle Associates Ltd1,730,821$2.65M0.05%+14,990+0.9%Added
Schonfeld Strategic Advisors LLC1,882,600$2.96M0.02%+1,311,108+229.4%Added
Nantahala Capital Management, LLC2,304,150$3.62M0.30%00.0%Unchanged
Ameriprise Financial Inc2,327,110$3.65M0.00%+234,400+11.2%Added
NEA Management Company, LLC2,382,286$3.74M0.20%00.0%Unchanged
State Street Corp2,471,215$3.88M0.00%+157,738+6.8%Added
Geode Capital Management, LLC3,523,971$5.53M0.00%+273,436+8.4%Added
Vanguard Group Inc8,091,098$12.7M0.00%+415,973+5.4%Added
BlackRock, Inc.10,133,014$15.9M0.00%+10,133,014New
OrbiMed Advisors LLC11,024,000$17.3M0.32%+5,177,900+88.6%Added
Siren, L.L.C.38,918,903$61.1M3.06%+38,918,903New
FMR LLC49,867,042$78.3M0.00%+11,179,919+28.9%Added
Artal Group S.A.136,180,481$213.8M8.98%−38,918,903−22.2%Reduced
Opaleye Management Inc.0$00.00%−1,875,000−100.0%Sold out
Altium Capital Management LP0$00.00%−121,986−100.0%Sold out
Simplex Trading, LLC0$00.00%−84,637−100.0%Sold out
Great Point Partners LLC0$00.00%−30,000−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−23,531−100.0%Sold out
Principal Financial Group Inc0$00.00%−22,759−100.0%Sold out
Verition Fund Management LLC0$00.00%−18,158−100.0%Sold out
Coyle Financial Counsel LLC0$00.00%−12,500−100.0%Sold out
CIBC World Markets Inc.0$00.00%−10,980−100.0%Sold out
Smartleaf Asset Management LLC0$00.00%−726−100.0%Sold out
Innealta Capital, LLC0$00.00%−175−100.0%Sold out
Optiver Holding B.V.0$00.00%−155−100.0%Sold out
Comerica Bank0$00.00%−122−100.0%Sold out
Rothschild Investment LLC0$00.00%−75−100.0%Sold out
BlackRock Inc.––––Not filed
CVI Holdings, LLC––––Not filed