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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
118
+13 vs. Q4 2023
Shares held
172.8M
−10.0M (−5.5%) vs. Q4 2023
Total value
$417.8M
+$138.0M (+49.3%) vs. Q4 2023
New holders
33
31 more added
Sold out
20
31 more reduced

1 institution that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 118 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ1 2024: $417.8M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2023.

Institutions holding LXRX in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Millennium Management LLC534,184$1.28M0.00%−1,098,992−67.3%Reduced
Point72 Asset Management, L.P.584,386$1.40M0.00%+584,386New
Wellington Management Group LLP686,418$1.65M0.00%+686,418New
Northern Trust Corp866,556$2.08M0.00%+6,968+0.8%Added
Charles Schwab Investment Management Inc881,123$2.11M0.00%+16,948+2.0%Added
Cubist Systematic Strategies, LLC1,404,928$3.37M0.04%+1,404,928New
Ameriprise Financial Inc1,417,950$3.40M0.00%−472,250−25.0%Reduced
BVF Inc1,686,924$4.05M0.11%−22,748,708−93.1%Reduced
Pinnacle Associates Ltd1,747,830$4.19M0.07%+17,009+1.0%Added
State Street Corp1,987,510$4.77M0.00%+95,191+5.0%Added
Schonfeld Strategic Advisors LLC960,150$5.35M0.04%+960,150New
NEA Management Company, LLC2,382,286$5.72M0.35%00.0%Unchanged
Geode Capital Management, LLC2,389,137$5.73M0.00%+40,221+1.7%Added
OrbiMed Advisors LLC3,542,000$8.50M0.17%+3,542,000New
Vanguard Group Inc6,401,225$15.4M0.00%+420,854+7.0%Added
BlackRock Inc.7,693,277$18.5M0.00%+688,124+9.8%Added
FMR LLC13,894,062$33.3M0.00%+11,617,594+510.3%Added
Artal Group S.A.117,553,284$282.1M7.27%00.0%Unchanged
Renaissance Technologies LLC0$00.00%−412,175−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−359,210−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−323,968−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−282,467−100.0%Sold out
Deerfield Management Company, L.P. (Series C)0$00.00%−103,144−100.0%Sold out
Simplex Trading, LLC0$00.00%−54,248−100.0%Sold out
Amundi0$00.00%−54,532−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−47,101−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−38,268−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−32,119−100.0%Sold out
Rpo LLC0$00.00%−32,000−100.0%Sold out
Oppenheimer & Co Inc0$00.00%−24,500−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−16,522−100.0%Sold out
Group One Trading, L.P.0$00.00%−16,054−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−14,400−100.0%Sold out
Wolverine Trading, LLC0$00.00%−14,018−100.0%Sold out
Assetmark, Inc0$00.00%−10,000−100.0%Sold out
Advisory Services Network, LLC0$00.00%−242−100.0%Sold out
Headlands Technologies LLC0$00.00%−204−100.0%Sold out
JNBA Financial Advisors0$00.00%−13−100.0%Sold out
Coppell Advisory Solutions LLC––––Not filed