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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
106
−6 vs. Q3 2023
Shares held
182.9M
−5.94M (−3.1%) vs. Q3 2023
Total value
$279.8M
+$74.0M (+36.0%) vs. Q3 2023
New holders
25
30 more added
Sold out
31
24 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 106 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ4 2023: $279.8M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q3 2023.

Institutions holding LXRX in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
NEA Management Company, LLC2,382,286$3.64M0.24%00.0%Unchanged
JPMorgan Chase & Co3,043,291$4.66M0.00%+228,257+8.1%Added
Vanguard Group Inc5,980,371$9.15M0.00%−419,840−6.6%Reduced
BlackRock Inc.7,005,153$10.7M0.00%+350,187+5.3%Added
BVF Inc24,435,632$37.4M0.94%+4,440,300+22.2%Added
Artal Group S.A.117,553,284$179.9M6.13%00.0%Unchanged
Octagon Capital Advisors LP0$00.00%−1,923,076−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−1,136,413−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−509,484−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−469,666−100.0%Sold out
Wellington Management Group LLP0$00.00%−378,701−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−310,815−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−277,248−100.0%Sold out
Swiss National Bank0$00.00%−242,300−100.0%Sold out
ClariVest Asset Management LLC0$00.00%−192,398−100.0%Sold out
Credit Suisse AG0$00.00%−145,746−100.0%Sold out
UBS Asset Management Americas Inc0$00.00%−137,735−100.0%Sold out
Verition Fund Management LLC0$00.00%−91,700−100.0%Sold out
Squarepoint Ops LLC0$00.00%−62,243−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−62,077−100.0%Sold out
MetLife Investment Management0$00.00%−42,834−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−34,844−100.0%Sold out
Arizona State Retirement System0$00.00%−31,372−100.0%Sold out
Teacher Retirement System of Texas0$00.00%−30,937−100.0%Sold out
Point72 Middle East FZE0$00.00%−29,615−100.0%Sold out
AQR Capital Management LLC0$00.00%−29,558−100.0%Sold out
Janus Henderson Group PLC0$00.00%−29,470−100.0%Sold out
Beacon Pointe Advisors, LLC0$00.00%−22,800−100.0%Sold out
Traynor Capital Management, Inc.0$00.00%−21,909−100.0%Sold out
Zurcher Kantonalbank (Zurich Cantonalbank)0$00.00%−20,787−100.0%Sold out
Federated Hermes, Inc.0$00.00%−16,493−100.0%Sold out
Hudson Capital Management LLC0$00.00%−15,038−100.0%Sold out
Cambridge Investment Research Advisors, Inc.0$00.00%−14,239−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−4,595−100.0%Sold out
Great West Life Assurance Co0$00.00%−4,635−100.0%Sold out
Lindbrook Capital, LLC0$00.00%−2,049−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−184−100.0%Sold out