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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
112
−10 vs. Q2 2023
Shares held
188.8M
−2.51M (−1.3%) vs. Q2 2023
Total value
$205.8M
−$232.3M (−53.0%) vs. Q2 2023
New holders
11
44 more added
Sold out
21
30 more reduced

1 institution that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 112 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ3 2023: $205.8M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q2 2023.

Institutions holding LXRX in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
State Street Corp1,876,139$2.04M0.00%+146,027+8.4%Added
Pinnacle Associates Ltd1,912,869$2.09M0.04%−80,758−4.1%Reduced
Octagon Capital Advisors LP1,923,076$2.10M0.37%00.0%Unchanged
Geode Capital Management, LLC2,126,137$2.32M0.00%+285,700+15.5%Added
NEA Management Company, LLC2,382,286$2.60M0.20%00.0%Unchanged
JPMorgan Chase & Co2,815,034$3.07M0.00%−116,135−4.0%Reduced
Millennium Management LLC3,885,753$4.24M0.00%+1,251,580+47.5%Added
Vanguard Group Inc6,400,211$6.98M0.00%−56,741−0.9%Reduced
BlackRock Inc.6,654,966$7.25M0.00%+275,780+4.3%Added
FMR LLC7,563,076$8.24M0.00%−947,992−11.1%Reduced
BVF Inc19,995,332$21.8M0.59%00.0%Unchanged
Artal Group S.A.117,553,284$128.1M5.59%00.0%Unchanged
Fisher Asset Management, LLC0$00.00%−523,394−100.0%Sold out
Ghisallo Capital Management LLC0$00.00%−500,000−100.0%Sold out
AXA S.A.0$00.00%−356,400−100.0%Sold out
HRT Financial LP0$00.00%−198,676−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−179,327−100.0%Sold out
Marshall Wace, LLP0$00.00%−125,287−100.0%Sold out
Group One Trading, L.P.0$00.00%−93,363−100.0%Sold out
Natixis Advisors, L.P.0$00.00%−87,425−100.0%Sold out
Prudential Financial Inc0$00.00%−51,558−100.0%Sold out
CIBC Private Wealth Group, LLC0$00.00%−30,000−100.0%Sold out
State Board of Administration of Florida Retirement System0$00.00%−29,400−100.0%Sold out
Nebula Research & Development LLC0$00.00%−28,377−100.0%Sold out
Tucker Asset Management LLC0$00.00%−27,596−100.0%Sold out
Simplex Trading, LLC0$00.00%−20,926−100.0%Sold out
Virtu Financial LLC0$00.00%−19,948−100.0%Sold out
Jump Financial, LLC0$00.00%−19,280−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−15,875−100.0%Sold out
Kestra Advisory Services, LLC0$00.00%−14,257−100.0%Sold out
Diametric Capital, LP0$00.00%−13,988−100.0%Sold out
Pegasus Asset Management, Inc.0$00.00%−10,000−100.0%Sold out
CWM, LLC0$00.00%−230−100.0%Sold out
Tiaa, FSB––––Not filed