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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q2 2023

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
123
+19 vs. Q1 2023
Shares held
191.3M
+45.7M (+31.4%) vs. Q1 2023
Total value
$438.2M
+$84.3M (+23.8%) vs. Q1 2023
New holders
26
54 more added
Sold out
7
21 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 123 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ2 2023: $438.2M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2023.

Institutions holding LXRX in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ghisallo Capital Management LLC500,000$1.15M0.14%+500,000New
ClariVest Asset Management LLC511,374$1.17M0.06%+121,213+31.1%Added
Fisher Asset Management, LLC523,394$1.20M0.00%−126,332−19.4%Reduced
Goldman Sachs Group Inc553,008$1.27M0.00%+264,070+91.4%Added
Charles Schwab Investment Management Inc712,375$1.63M0.00%+23,764+3.5%Added
Dimensional Fund Advisors LP743,737$1.70M0.00%+24,555+3.4%Added
Ameriprise Financial Inc838,408$1.92M0.00%+838,408New
Northern Trust Corp1,081,831$2.48M0.00%+318,567+41.7%Added
D. E. Shaw & Co., Inc.1,213,726$2.78M0.00%−1,727,271−58.7%Reduced
Parkman Healthcare Partners LLC1,330,616$3.05M0.53%+655,288+97.0%Added
State Street Corp1,730,112$3.96M0.00%+166,014+10.6%Added
Alyeska Investment Group, L.P.1,742,352$3.99M0.03%+1,742,352New
Geode Capital Management, LLC1,840,437$4.21M0.00%+115,028+6.7%Added
Octagon Capital Advisors LP1,923,076$4.40M0.61%+1,923,076New
Pinnacle Associates Ltd1,993,627$4.57M0.08%+53,403+2.8%Added
NEA Management Company, LLC2,382,286$5.46M0.42%00.0%Unchanged
Millennium Management LLC2,634,173$6.03M0.01%+2,610,329+10,947.5%Added
JPMorgan Chase & Co2,931,169$6.71M0.00%−374,822−11.3%Reduced
BlackRock Inc.6,379,186$14.6M0.00%+722,259+12.8%Added
Vanguard Group Inc6,456,952$14.8M0.00%+1,157,572+21.8%Added
FMR LLC8,511,068$19.5M0.00%+3,270,821+62.4%Added
BVF Inc19,995,332$45.8M1.28%+3,846,153+23.8%Added
Artal Group S.A.117,553,284$269.2M8.62%+27,775,050+30.9%Added
Point72 Asset Management, L.P.0$00.00%−516,367−100.0%Sold out
Renaissance Technologies LLC0$00.00%−263,875−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−69,791−100.0%Sold out
SG Americas Securities, LLC0$00.00%−37,689−100.0%Sold out
Squarepoint Ops LLC0$00.00%−23,938−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−15,536−100.0%Sold out
Advisory Services Network, LLC0$00.00%−242−100.0%Sold out