Skip to main content

Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
368
+41 vs. Q4 2025
Shares held
28.4M
+3.02M (+11.9%) vs. Q4 2025
Total value
$7.32B
+$1.08B (+17.2%) vs. Q4 2025
New holders
76
138 more added
Sold out
35
105 more reduced

7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 368 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ1 2026: $7.32B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2025.

Institutions holding KRYS in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Los Angeles Capital Management LLC2,171$560.8K0.00%00.0%Unchanged
Swiss Life Asset Management Ltd2,165$559.3K0.00%+1,174+118.5%Added
Vontobel Holding Ltd.2,118$547.1K0.00%−37−1.7%Reduced
Ballentine Partners, LLC2,115$546.3K0.01%+7+0.3%Added
Ameritas Investment Partners, Inc.2,055$530.8K0.02%+42+2.1%Added
HighTower Advisors, LLC2,049$529.3K0.00%+937+84.3%Added
Yorktown Management & Research Co Inc2,000$516.6K0.43%00.0%Unchanged
Alps Advisors Inc2,000$516.6K0.00%+2,000New
The PNC Financial Services Group, Inc.1,985$512.8K0.00%+289+17.0%Added
AlphaCentric Advisors LLC1,918$495.5K0.49%+105+5.8%Added
Allianz Asset Management GmbH1,900$490.8K0.00%00.0%Unchanged
Bokf, NA1,829$472.5K0.01%+1,829New
Measured Wealth Private Client Group, LLC1,826$471.7K0.13%+1,826New
HighVista Strategies LLC1,824$471.2K0.13%+1,824New
O'Shaughnessy Asset Management, LLC1,823$470.9K0.00%−600−24.8%Reduced
LPL Financial LLC1,765$455.9K0.00%+611+52.9%Added
Natixis1,736$448.4K0.00%−1,184−40.5%Reduced
Optimize Financial Inc1,710$441.7K0.22%−1,145−40.1%Reduced
Aviva PLC1,691$436.8K0.00%−537−24.1%Reduced
Parallel Advisors, LLC1,688$436.0K0.01%+8+0.5%Added
Cynosure Management, LLC1,649$426.0K0.05%−757−31.5%Reduced
Vident Advisory, LLC1,614$416.9K0.00%+120+8.0%Added
Sound View Wealth Advisors Group, LLC1,594$411.8K0.03%+15+0.9%Added
IMC-Chicago, LLC1,591$411.0K0.01%+1,591New
Mirae Asset Global Investments Co., Ltd.1,525$393.9K0.00%+116+8.2%Added
CWM, LLC1,488$384.4K0.00%−20−1.3%Reduced
Stratos Wealth Partners, LTD.1,459$376.9K0.00%00.0%Unchanged
Mindset Wealth Management, LLC1,450$374.6K0.10%−343−19.1%Reduced
Kingswood Wealth Advisors, LLC1,390$359.1K0.02%+1,390New
Ensign Peak Advisors, Inc1,369$353.6K0.00%00.0%Unchanged
Vise Technologies, Inc.1,424$351.1K0.01%00.0%Unchanged
Gotham Asset Management, LLC1,323$341.8K0.00%+20+1.5%Added
Vestcor Inc1,311$339.0K0.01%+1,311New
Net Worth Advisory Group1,307$337.6K0.07%+384+41.6%Added
Hidden Cove Wealth Management, LLC1,302$336.3K0.22%+443+51.6%Added
Hudson Bay Capital Management LP1,300$335.8K0.00%+1,300New
QRG Capital Management, Inc.1,281$330.9K0.00%+1,281New
CIBC Bancorp USA Inc.1,265$326.8K0.00%+1,265New
Argent Trust Co1,261$325.7K0.01%00.0%Unchanged
New Age Alpha Advisors, LLC1,202$310.5K0.01%−18−1.5%Reduced
Captrust Financial Advisors1,179$304.6K0.00%+4+0.3%Added
Ethic Inc.1,166$301.2K0.00%+203+21.1%Added
Truist Financial Corp1,164$300.7K0.00%+84+7.8%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,147$296.3K0.00%−28−2.4%Reduced
Squarepoint Ops LLC1,138$294.0K0.00%+1,138New
Mount Yale Investment Advisors, LLC1,130$291.9K0.01%+1,130New
GTS Securities LLC1,108$286.2K0.01%+1,108New
Evergreen Capital Management LLC1,094$282.6K0.01%+8+0.7%Added
Toroso Investments, LLC1,088$281.1K0.00%+1,088New
Linden Thomas Advisory Services, LLC1,072$276.9K0.03%+1,072New
Mariner, LLC1,048$270.5K0.00%−3,272−75.7%Reduced
Royal Bank of Canada1,033$268.0K0.00%−468−31.2%Reduced
Hohimer Wealth Management, LLC1,034$267.1K0.03%−180−14.8%Reduced
Fifth Third Wealth Advisors LLC1,019$263.2K0.01%+1,019New
MAI Capital Management1,010$260.9K0.00%+726+255.6%Added
Farallon Capital Management, L.L.C.1,000$258.3K0.00%−1,000−50.0%Reduced
Welch Group, LLC1,000$258.3K0.01%+1,000New
D. E. Shaw & Co., Inc.996$257.3K0.00%−1,112−52.8%Reduced
Sequoia Financial Advisors, LLC993$256.5K0.00%−90−8.3%Reduced
Advisory Services Network, LLC965$249.3K0.00%+965New
NLB Skladi, upravljanje premozenja, d.o.o.955$246.7K0.01%00.0%Unchanged
Private Advisor Group, LLC947$244.6K0.00%+947New
Coldstream Capital Management Inc939$242.6K0.00%+16+1.7%Added
Nisa Investment Advisors, LLC937$242.0K0.00%+7+0.8%Added
CIBC Asset Management Inc888$229.4K0.00%00.0%Unchanged
GAMMA Investing LLC858$221.6K0.01%+69+8.7%Added
DRW Securities, LLC857$221.4K0.01%+857New
RSM US Wealth Management LLC852$220.1K0.00%+852New
Fiduciary Trust Co840$217.0K0.00%00.0%Unchanged
Shelton Capital Management840$217.0K0.00%00.0%Unchanged
Greenwood Capital Associates LLC834$215.4K0.02%+834New
Brinker Capital Investments, LLC828$213.8K0.00%−99−10.7%Reduced
Everence Capital Management Inc800$207.0K0.01%+800New
Camden Capital, LLC800$206.7K0.01%+800New
Pinnacle Wealth Planning Services, Inc.794$205.1K0.02%+35+4.6%Added
Oppenheimer Asset Management Inc.793$204.8K0.00%−251−24.0%Reduced
Archer Investment Corp730$188.6K0.04%+730New
Exchange Traded Concepts, LLC688$177.7K0.00%−238−25.7%Reduced
KBC Group NV685$177.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.651$168.2K0.00%+82+14.4%Added
Jones Financial Companies LLLP655$162.3K0.00%+365+125.9%Added
Eurizon Capital SGR S.p.A.553$137.2K0.00%00.0%Unchanged
Hantz Financial Services, Inc.474$122.0K0.00%+103+27.8%Added
Advisor Group Holdings, Inc.423$109.3K0.00%−6,309−93.7%Reduced
Bryn Mawr Trust Co393$101.5K0.00%00.0%Unchanged
BNP PARIBAS ASSET MANAGEMENT Holding S.A.355$91.7K0.00%+93+35.5%Added
Walleye Capital LLC354$91.4K0.00%+354New
Horizon Investments, LLC304$78.5K0.00%−108−26.2%Reduced
Covestor Ltd300$78.0K0.05%−941−75.8%Reduced
Smartleaf Asset Management LLC308$76.1K0.00%−302−49.5%Reduced
Advisors Asset Management, Inc.292$75.4K0.00%+211+260.5%Added
Caldwell Trust Co250$64.6K0.01%00.0%Unchanged
Quadrant Capital Group LLC236$61.0K0.00%+80+51.3%Added
US Bancorp234$60.4K0.00%−79−25.2%Reduced
Rockefeller Capital Management L.P.231$59.7K0.00%+175+312.5%Added
Kemnay Advisory Services Inc.216$55.8K0.01%+132+157.1%Added
Salomon & Ludwin, LLC201$52.5K0.00%+18+9.8%Added
Vestor Capital, LLC200$52.0K0.00%−2,740−93.2%Reduced
Cullen/Frost Bankers, Inc.187$48.3K0.00%+187New
Huntington National Bank183$47.3K0.00%−5−2.7%Reduced