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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
368
+41 vs. Q4 2025
Shares held
28.4M
+3.02M (+11.9%) vs. Q4 2025
Total value
$7.32B
+$1.08B (+17.2%) vs. Q4 2025
New holders
76
138 more added
Sold out
35
105 more reduced

7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 368 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ1 2026: $7.32B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2025.

Institutions holding KRYS in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
AdvisorNet Financial, Inc171$44.2K0.00%00.0%Unchanged
USA Financial Portformulas Corp171$44.2K0.01%+171New
Sterling Capital Management LLC161$41.6K0.00%−1−0.6%Reduced
Key Financial Inc151$39.0K0.01%00.0%Unchanged
Umb Bank N A151$39.0K0.00%+7+4.9%Added
Sound Income Strategies, LLC137$35.5K0.00%00.0%Unchanged
Quantbot Technologies LP133$34.4K0.00%+47+54.7%Added
EverSource Wealth Advisors, LLC108$27.9K0.00%+33+44.0%Added
Signaturefd, LLC105$27.1K0.00%+16+18.0%Added
Twin Peaks Wealth Advisors, LLC105$27.1K0.01%+105New
Reyes Financial Architecture, Inc.100$25.8K0.02%00.0%Unchanged
Steward Partners Investment Advisory, LLC100$25.8K0.00%+100New
Massmutual Trust Co FSB86$22.2K0.00%+1+1.2%Added
Basecamp Wealth Advisors LLC85$22.0K0.00%−9−9.6%Reduced
Versant Capital Management, Inc74$19.1K0.00%+3+4.2%Added
Dauntless Investment Group, LLC73$18.9K0.05%+73New
SBI Securities Co., Ltd.69$17.8K0.00%−133−65.8%Reduced
IFP Advisors, Inc65$16.8K0.00%−200−75.5%Reduced
E Fund Management (Hong Kong) Co., Ltd.57$14.7K0.01%+57New
Farther Finance Advisors, LLC55$14.2K0.00%+16+41.0%Added
Private Wealth Management Group, LLC55$14.2K0.00%00.0%Unchanged
Simplex Trading, LLC50$12.9K0.00%−243−82.9%Reduced
Federation des caisses Desjardins du Quebec50$12.9K0.00%00.0%Unchanged
Allworth Financial LP48$12.4K0.00%+21+77.8%Added
Bare Financial Services, Inc47$12.1K0.00%+4+9.3%Added
GWM Advisors LLC37$9.64K0.00%−35−48.6%Reduced
Westside Investment Management, Inc.35$9.13K0.00%+35New
Parkside Financial Bank & Trust34$8.78K0.00%+1+3.0%Added
Acumen Wealth Advisors, LLC34$8.78K0.00%00.0%Unchanged
Quent Capital, LLC34$8.78K0.00%00.0%Unchanged
Harbour Investments, Inc.33$8.53K0.00%00.0%Unchanged
Rothschild Investment LLC28$7.23K0.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.28$7.23K0.00%+23+460.0%Added
Root Financial Partners, LLC17$4.39K0.00%+10+142.9%Added
Bell Investment Advisors, Inc16$4.13K0.00%00.0%Unchanged
Larson Financial Group LLC16$4.13K0.00%−1−5.9%Reduced
Farmers & Merchants Investments Inc15$3.88K0.00%00.0%Unchanged
Cornerstone Financial Management LLC14$3.62K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co13$3.36K0.00%+13New
Zions Bancorporation, National Association12$3.10K0.00%+12New
Fortitude Family Office, LLC11$2.84K0.00%+4+57.1%Added
JPL Wealth Management, LLC10$2.58K0.00%+10New
IMA Wealth, Inc.10$2.58K0.00%+10New
Retirement Wealth Solutions LLC8$2.07K0.00%+1+14.3%Added
Rachor Investment Advisory Services, LLC8$2.07K0.00%+8New
Colonial Trust Co8$1.98K0.00%+8New
Toth Financial Advisory Corp6$1.55K0.00%+6New
Glen Eagle Advisors, LLC5$1.29K0.00%00.0%Unchanged
Ankerstar Wealth, LLC5$1.29K0.00%+1+25.0%Added
Hughes Financial Services, LLC5$1.29K0.00%+1+25.0%Added
JFS Wealth Advisors, LLC5$1.29K0.00%+2+66.7%Added
International Assets Investment Management, LLC4$1.04K0.00%+4New
SRS Capital Advisors, Inc.4$1.03K0.00%−28−87.5%Reduced
SJS Investment Consulting Inc.4$1.03K0.00%+1+33.3%Added
UMA Financial Services, Inc.4$1.03K0.00%+2+100.0%Added
Gilpin Wealth Management, LLC4$1.03K0.00%+2+100.0%Added
Ronald Blue Trust, Inc.4$1.03K0.00%00.0%Unchanged
Essential Partners LLC4$1.03K0.00%00.0%Unchanged
Avion Wealth6$1.00K0.00%00.0%Unchanged
Vermillion Wealth Management, Inc.3$7750.00%+3New
Cedar Mountain Advisors, LLC3$7750.00%+3New
CVA Family Office, LLC3$7750.00%+3New
Trust Co2$5170.00%00.0%Unchanged
Signature Equity Partners, LLC2$5170.00%00.0%Unchanged
Abound Wealth Management1$2590.00%00.0%Unchanged
Rialto Wealth Management, LLC1$2590.00%00.0%Unchanged
Prestige Wealth Management Group LLC1$2590.00%+1New
Ameritas Advisory Services, LLC1$2580.00%+1New
Skandinaviska Enskilda Banken AB (publ)0$00.00%−46,732−100.0%Sold out
Perceptive Advisors LLC0$00.00%−17,500−100.0%Sold out
Verition Fund Management LLC0$00.00%−16,969−100.0%Sold out
Ikarian Capital, LLC0$00.00%−14,814−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−15,503−100.0%Sold out
Main Management ETF Advisors, LLC0$00.00%−10,179−100.0%Sold out
Perigon Wealth Management, LLC0$00.00%−8,970−100.0%Sold out
NFJ Investment Group, LLC0$00.00%−8,249−100.0%Sold out
Winton Group Ltd0$00.00%−5,874−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−3,527−100.0%Sold out
Baader Bank INC0$00.00%−3,163−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−2,902−100.0%Sold out
EP Wealth Advisors, LLC0$00.00%−1,846−100.0%Sold out
City Center Advisors, LLC0$00.00%−1,628−100.0%Sold out
Mackenzie Financial Corp0$00.00%−1,554−100.0%Sold out
J. Goldman & Co LP0$00.00%−1,535−100.0%Sold out
Cerity Partners LLC0$00.00%−1,361−100.0%Sold out
Roman Butler Fullerton & Co0$00.00%−1,125−100.0%Sold out
Lazard Asset Management LLC0$00.00%−1,058−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−1,032−100.0%Sold out
Avanza Fonder AB0$00.00%−996−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−856−100.0%Sold out
Canada Pension Plan Investment Board0$00.00%−600−100.0%Sold out
Quest Partners LLC0$00.00%−565−100.0%Sold out
Danske Bank A/S0$00.00%−200−100.0%Sold out
Greenline Wealth Management LLC0$00.00%−136−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−86−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−57−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−28−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−27−100.0%Sold out
Accent Capital Management, LLC0$00.00%−15−100.0%Sold out
Flagship Harbor Advisors, LLC0$00.00%−2−100.0%Sold out