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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
194
+9 vs. Q3 2023
Shares held
24.4M
+670.7K (+2.8%) vs. Q3 2023
Total value
$3.03B
+$274.6M (+10.0%) vs. Q3 2023
New holders
29
72 more added
Sold out
20
66 more reduced

3 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 194 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ4 2023: $3.03B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2023.

Institutions holding KRYS in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Avoro Capital Advisors LLC2,565,555$318.3M4.40%00.0%Unchanged
Vanguard Group Inc2,435,774$302.2M0.01%+35,632+1.5%Added
FMR LLC2,385,898$296.0M0.02%−243,485−9.3%Reduced
BlackRock Inc.1,809,547$224.5M0.01%+107,303+6.3%Added
Redmile Group, LLC1,733,189$215.0M7.69%−270,178−13.5%Reduced
State Street Corp1,237,497$153.5M0.01%+205,670+19.9%Added
Frazier Life Sciences Management, L.P.988,460$122.6M6.56%00.0%Unchanged
Jennison Associates LLC724,344$89.9M0.07%+383,495+112.5%Added
Lord, Abbett & Co. LLC618,458$76.7M0.27%−52,853−7.9%Reduced
Dimensional Fund Advisors LP550,806$68.3M0.02%+30,169+5.8%Added
Geode Capital Management, LLC511,246$63.4M0.01%+28,011+5.8%Added
Woodline Partners LP481,979$59.8M0.65%+160,035+49.7%Added
Credit Suisse AG474,484$58.9M0.06%+240,863+103.1%Added
Hood River Capital Management LLC458,513$56.9M1.56%−1,976−0.4%Reduced
Price T Rowe Associates Inc427,363$53.0M0.01%+171,157+66.8%Added
Morgan Stanley319,721$39.7M0.00%+31,169+10.8%Added
Nuveen Asset Management, LLC315,465$39.1M0.01%+53,231+20.3%Added
Balyasny Asset Management LLC256,604$31.8M0.09%+223,962+686.1%Added
TimesSquare Capital Management, LLC250,470$31.1M0.46%+127,435+103.6%Added
Skandinaviska Enskilda Banken AB (publ)244,061$30.3M0.18%00.0%Unchanged
First Turn Management, LLC242,185$30.0M4.31%+242,185New
Goldman Sachs Group Inc228,053$28.3M0.01%+43,709+23.7%Added
JPMorgan Chase & Co213,519$26.5M0.00%−7,974−3.6%Reduced
Northern Trust Corp209,199$26.0M0.00%−4,064−1.9%Reduced
Driehaus Capital Management LLC196,386$24.4M0.29%−2,297−1.2%Reduced
Braidwell LP196,200$24.3M0.89%+118,703+153.2%Added
Pictet Asset Management Holding SA192,875$23.9M0.03%−180,937−48.4%Reduced
C WorldWide Group Holding A/S185,809$23.1M0.31%00.0%Unchanged
Charles Schwab Investment Management Inc185,038$23.0M0.01%+5,258+2.9%Added
Victory Capital Management Inc172,879$21.4M0.02%−36,608−17.5%Reduced
Baker Bros. Advisors LP169,934$21.1M0.24%00.0%Unchanged
Fred Alger Management, LLC160,335$19.9M0.11%−7,150−4.3%Reduced
Eventide Asset Management, LLC136,485$16.9M0.28%+136,485New
Handelsbanken Fonder AB123,200$15.3M0.07%+10,400+9.2%Added
S Squared Technology, LLC110,215$13.7M6.64%+2,000+1.8%Added
Rock Springs Capital Management LP103,969$12.9M0.32%+13,409+14.8%Added
OrbiMed Advisors LLC103,700$12.9M0.26%+103,700New
Bank of New York Mellon Corp98,651$12.2M0.00%+431+0.4%Added
Verition Fund Management LLC95,958$11.9M0.12%−31,112−24.5%Reduced
Bank of America Corp91,193$11.3M0.00%+27,968+44.2%Added
Integral Health Asset Management, LLC85,000$10.5M1.52%+15,000+21.4%Added
Rafferty Asset Management, LLC84,021$10.4M0.04%+12,215+17.0%Added
Eversept Partners, LP80,798$10.0M0.98%−27,973−25.7%Reduced
Schroder Investment Management Group74,945$9.30M0.01%+74,945New
Marshall Wace, LLP70,901$8.80M0.02%+61,373+644.1%Added
D. E. Shaw & Co., Inc.67,141$8.33M0.01%+11,384+20.4%Added
Decheng Capital LLC65,772$8.16M2.28%+65,772New
Barclays PLC64,179$7.96M0.00%+24,659+62.4%Added
Allspring Global Investments Holdings, LLC59,324$7.36M0.01%+4,588+8.4%Added
Candriam Luxembourg S.C.A.55,000$6.82M0.05%−15,000−21.4%Reduced
Invesco Ltd.54,229$6.73M0.00%+10,030+22.7%Added
Man Group plc50,836$6.31M0.02%+50,836New
Jane Street Group, LLC50,618$6.28M0.01%−24,508−32.6%Reduced
Ghost Tree Capital, LLC50,000$6.20M3.57%−30,000−37.5%Reduced
Nicholas Investment Partners, LP49,073$6.09M0.71%−306,538−86.2%Reduced
Voya Investment Management LLC47,597$5.90M0.01%+19,157+67.4%Added
ExodusPoint Capital Management, LP42,502$5.27M0.07%+14,752+53.2%Added
TD Asset Management Inc40,962$5.08M0.00%+18,542+82.7%Added
Soleus Capital Management, L.P.40,000$4.96M0.55%−77,892−66.1%Reduced
Prudential Financial Inc39,556$4.91M0.01%−30−0.1%Reduced
Putnam Investments LLC39,322$4.88M0.01%+4,529+13.0%Added
BNP Paribas Arbitrage, SA39,072$4.85M0.01%+10,057+34.7%Added
Citigroup Inc36,566$4.54M0.01%+779+2.2%Added
Mutual of America Capital Management LLC36,388$4.51M0.05%−1,151−3.1%Reduced
Swiss National Bank35,900$4.45M0.00%−3,500−8.9%Reduced
Castleark Management LLC32,350$4.01M0.18%+20,930+183.3%Added
Rhumbline Advisers31,785$3.94M0.00%−618−1.9%Reduced
Hennion & Walsh Asset Management, Inc.31,398$3.90M0.22%−19,423−38.2%Reduced
UBS Group AG30,760$3.82M0.00%+30,760New
CWM, LLC30,569$3.79M0.02%−1,757−5.4%Reduced
Kennedy Capital Management, Inc.29,673$3.68M0.08%+29,673New
Manufacturers Life Insurance Company, The29,250$3.63M0.00%+8,813+43.1%Added
Franklin Resources Inc26,546$3.29M0.00%+68+0.3%Added
Alliancebernstein L.P.25,900$3.21M0.00%00.0%Unchanged
Schonfeld Strategic Advisors LLC25,566$3.17M0.03%−58,069−69.4%Reduced
Russell Investments Group, Ltd.25,479$3.16M0.01%−13,219−34.2%Reduced
Affinity Asset Advisors, LLC25,000$3.10M0.62%−32,500−56.5%Reduced
State of New Jersey Common Pension Fund D24,804$3.08M0.01%+4,475+22.0%Added
HRT Financial LP22,886$2.84M0.02%+22,886New
UBS Asset Management Americas Inc20,426$2.53M0.00%00.0%Unchanged
California State Teachers Retirement System19,769$2.45M0.00%−844−4.1%Reduced
Legal & General Group Plc19,092$2.37M0.00%−435−2.2%Reduced
SG Americas Securities, LLC18,865$2.34M0.03%−2,074−9.9%Reduced
Deutsche Bank AG18,830$2.34M0.00%+5,331+39.5%Added
Erste Asset Management GmbH18,200$2.33M0.03%+12,800+237.0%Added
Cowen and Company, LLC16,634$2.06M0.14%+16,634New
Superstring Capital Management LP16,086$2.00M1.42%+16,086New
Ameriprise Financial Inc15,939$1.98M0.00%+3,960+33.1%Added
Fiera Capital Corp15,900$1.97M0.01%+15,900New
DekaBank Deutsche Girozentrale15,503$1.97M0.00%00.0%Unchanged
Calamos Advisors LLC15,705$1.95M0.01%−9,942−38.8%Reduced
Point72 Asset Management, L.P.15,299$1.90M0.01%−682,859−97.8%Reduced
New York State Common Retirement Fund14,993$1.86M0.00%−7,091−32.1%Reduced
State of Wisconsin Investment Board14,896$1.85M0.01%−5,731−27.8%Reduced
SEI Investments Co14,784$1.83M0.00%−20,117−57.6%Reduced
Profund Advisors LLC13,782$1.71M0.07%+1,542+12.6%Added
Mirae Asset Global Investments Co., Ltd.13,484$1.67M0.00%+969+7.7%Added
Martingale Asset Management L P11,687$1.45M0.03%−80−0.7%Reduced
MetLife Investment Management11,371$1.41M0.01%00.0%Unchanged
Norges Bank11,340$1.41M0.00%−6,796−37.5%Reduced