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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
140
+27 vs. Q3 2021
Shares held
19.3M
+3.02M (+18.5%) vs. Q3 2021
Total value
$1.35B
+$500.0M (+58.8%) vs. Q3 2021
New holders
48
56 more added
Sold out
21
22 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 140 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ4 2021: $1.35B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2021.

Institutions holding KRYS in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC1,978,289$138.4M0.01%+75,884+4.0%Added
Point72 Asset Management, L.P.1,856,156$129.8M0.58%+1,321,456+247.1%Added
Redmile Group, LLC1,820,898$127.4M2.90%−161,534−8.1%Reduced
BlackRock Inc.1,605,496$112.3M0.00%+64,110+4.2%Added
Lord, Abbett & Co. LLC1,173,863$82.1M0.19%+106,705+10.0%Added
Vanguard Group Inc1,023,610$71.6M0.00%+134,952+15.2%Added
Baker Bros. Advisors LP807,735$56.5M0.27%+200,000+32.9%Added
Frazier Management LLC771,250$53.9M4.15%00.0%Unchanged
Credit Suisse AG753,680$52.7M0.04%−18,274−2.4%Reduced
State Street Corp701,801$49.1M0.00%−35,252−4.8%Reduced
Pictet Asset Management SA701,403$49.1M0.05%+63,911+10.0%Added
Artal Group S.A.700,000$49.0M1.44%+200,000+40.0%Added
First Light Asset Management, LLC680,170$47.6M3.41%+46,689+7.4%Added
Avoro Capital Advisors LLC475,000$33.2M0.57%+475,000New
Geode Capital Management, LLC329,926$23.1M0.00%+12,318+3.9%Added
Soleus Capital Management, L.P.228,437$16.0M2.16%+102,908+82.0%Added
Hood River Capital Management LLC225,727$15.8M0.47%−174−0.1%Reduced
Skandinaviska Enskilda Banken AB (publ)208,826$14.7M0.08%+75,825+57.0%Added
JPMorgan Chase & Co199,633$14.0M0.00%−24,786−11.0%Reduced
Nicholas Investment Partners, LP191,311$13.4M0.85%−65,564−25.5%Reduced
C WorldWide Group Holding A/S185,809$13.0M0.12%00.0%Unchanged
Northern Trust Corp183,559$12.8M0.00%+2,125+1.2%Added
Dimensional Fund Advisors LP150,641$10.5M0.00%−13,223−8.1%Reduced
Charles Schwab Investment Management Inc139,618$9.77M0.00%+14,234+11.4%Added
Morgan Stanley110,998$7.76M0.00%+77,764+234.0%Added
Marshall Wace, LLP108,511$7.59M0.02%+82,856+323.0%Added
S Squared Technology, LLC95,215$6.66M2.98%+10,000+11.7%Added
Handelsbanken Fonder AB90,000$6.30M0.03%00.0%Unchanged
Bank of New York Mellon Corp83,451$5.84M0.00%+7,022+9.2%Added
Nuveen Asset Management, LLC78,178$5.47M0.00%−4,122−5.0%Reduced
Verition Fund Management LLC76,114$5.32M0.07%+10,069+15.2%Added
Millennium Management LLC61,429$4.30M0.00%+36,619+147.6%Added
CWM, LLC59,935$4.19M0.03%+59,935New
ACT Capital Management, LLC59,000$4.13M2.98%+19,000+47.5%Added
Goldman Sachs Group Inc53,153$3.72M0.00%+31,828+149.3%Added
SG Americas Securities, LLC52,470$3.67M0.02%+288+0.6%Added
Jacob Asset Management of New York LLC50,922$3.56M1.59%+25,878+103.3%Added
Silverarc Capital Management, LLC46,670$3.27M1.46%+46,670New
International Biotechnology Trust PLC45,000$3.15M0.70%+45,000New
Parametric Portfolio Associates LLC39,447$2.76M0.00%+33,525+566.1%Added
Citadel Advisors LLC38,745$2.71M0.00%+7,742+25.0%Added
Swiss National Bank38,400$2.69M0.00%+6,600+20.8%Added
DnB Asset Management AS35,640$2.49M0.01%+35,640New
Citigroup Inc34,888$2.44M0.00%+4,926+16.4%Added
EAM Investors, LLC34,867$2.44M0.40%+34,867New
Kynam Capital Management, LP34,816$2.44M1.30%+34,816New
Parallel Advisors, LLC34,036$2.38M0.09%+28,582+524.1%Added
Rafferty Asset Management, LLC32,493$2.27M0.01%+9,239+39.7%Added
Mutual of America Capital Management LLC30,237$2.12M0.02%−281−0.9%Reduced
Alps Advisors Inc28,819$2.02M0.02%+1,606+5.9%Added
Jane Street Group, LLC27,684$1.94M0.00%+27,684New
Caption Management, LLC27,300$1.91M0.12%+27,300New
State of Wisconsin Investment Board27,200$1.90M0.00%+3,800+16.2%Added
Vontobel Holding Ltd.26,910$1.88M0.02%+5,512+25.8%Added
Voloridge Investment Management, LLC26,517$1.85M0.01%+26,517New
Barclays PLC25,861$1.81M0.00%+13,161+103.6%Added
California State Teachers Retirement System24,416$1.71M0.00%+2,954+13.8%Added
New York State Common Retirement Fund24,219$1.69M0.00%−1,940−7.4%Reduced
EAM Global Investors LLC21,959$1.54M0.27%+21,959New
Squarepoint Ops LLC21,794$1.52M0.01%+8,909+69.1%Added
Rhumbline Advisers21,667$1.52M0.00%+123+0.6%Added
Allianz Asset Management GmbH21,159$1.48M0.00%+21,159New
Alliancebernstein L.P.20,700$1.45M0.00%00.0%Unchanged
Harbor Capital Advisors, Inc.18,472$1.29M0.47%+18,472New
HighMark Wealth Management LLC17,185$1.20M0.76%−191−1.1%Reduced
Ergoteles LLC17,002$1.19M0.05%+17,002New
SEI Investments Co16,415$1.15M0.00%+9,437+135.2%Added
Wells Fargo & Company14,965$1.05M0.00%+9,288+163.6%Added
Deutsche Bank AG14,938$1.04M0.00%+583+4.1%Added
SG3 Management, LLC14,879$1.04M0.11%+14,879New
Hennion & Walsh Asset Management, Inc.14,137$989.0K0.05%+14,137New
Bellevue Group AG14,000$979.0K0.01%+14,000New
Susquehanna International Group, LLP13,484$943.0K0.00%+1,028+8.3%Added
Bank of America Corp13,209$924.0K0.00%+6,099+85.8%Added
Tudor Investment Corp Et Al12,562$879.0K0.02%+12,562New
HRT Financial LP12,110$847.0K0.00%+12,110New
Connor, Clark & Lunn Investment Management Ltd.11,371$795.0K0.00%+11,371New
UBS Asset Management Americas Inc10,193$713.0K0.00%+1,488+17.1%Added
American International Group, Inc.9,531$667.0K0.00%−284−2.9%Reduced
Manufacturers Life Insurance Company, The9,327$652.0K0.00%−210−2.2%Reduced
Blair William & Co8,896$622.0K0.00%−84,242−90.4%Reduced
DekaBank Deutsche Girozentrale8,800$619.0K0.00%+200+2.3%Added
State Board of Administration of Florida Retirement System8,777$614.0K0.00%00.0%Unchanged
Cutler Group LP8,671$606.0K0.04%+8,671New
Price T Rowe Associates Inc8,105$567.0K0.00%+3,886+92.1%Added
Toronto Dominion Bank8,108$567.0K0.00%+8,108New
Invesco Ltd.7,681$538.0K0.00%−455−5.6%Reduced
Rock Creek Group, LP8,847$522.0K0.08%+8,847New
Caas Capital Management LP7,121$498.0K0.05%+7,121New
ProShare Advisors LLC7,046$493.0K0.00%+5+0.1%Added
Voya Investment Management LLC7,012$490.0K0.00%−49,223−87.5%Reduced
Quantum Private Wealth, LLC6,824$477.0K0.18%+6,824New
MetLife Investment Management6,648$465.0K0.00%00.0%Unchanged
Advisory Research Inc6,339$443.0K0.03%+6,339New
Legal & General Group Plc6,163$432.0K0.00%+568+10.2%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.5,916$427.0K0.00%+1,186+25.1%Added
Parallax Volatility Advisers, L.P.5,780$404.0K0.00%+5,780New
Tower Research Capital LLC (TRC)5,599$391.0K0.01%+3,189+132.3%Added
BNP Paribas Arbitrage, SA5,486$383.7K0.00%+1,557+39.6%Added
Taylor Wealth Management Partners5,315$372.0K0.13%−1,300−19.7%Reduced