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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
160
+8 vs. Q4 2022
Shares held
21.0M
+128.3K (+0.6%) vs. Q4 2022
Total value
$1.68B
+$27.6M (+1.7%) vs. Q4 2022
New holders
19
57 more added
Sold out
11
55 more reduced

2 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 160 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ1 2023: $1.68B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2022.

Institutions holding KRYS in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC2,196,958$175.9M0.02%+88,105+4.2%Added
Redmile Group, LLC1,913,280$153.2M6.65%+16,635+0.9%Added
Avoro Capital Advisors LLC1,750,000$140.1M2.08%+340,000+24.1%Added
BlackRock Inc.1,716,095$137.4M0.00%+16,499+1.0%Added
Vanguard Group Inc1,202,230$96.3M0.00%+14,120+1.2%Added
State Street Corp1,026,395$82.2M0.00%−12,588−1.2%Reduced
Lord, Abbett & Co. LLC961,242$77.0M0.28%−316,780−24.8%Reduced
Frazier Life Sciences Management, L.P.945,407$75.7M5.48%−54,330−5.4%Reduced
Credit Suisse AG632,824$50.7M0.05%−50,056−7.3%Reduced
Pictet Asset Management SA632,393$50.6M0.06%+6,414+1.0%Added
Point72 Asset Management, L.P.502,400$40.2M0.14%−53,852−9.7%Reduced
Dimensional Fund Advisors LP462,090$37.0M0.01%+72,805+18.7%Added
Hood River Capital Management LLC447,393$35.8M1.16%+20,514+4.8%Added
Geode Capital Management, LLC430,571$34.5M0.00%+18,444+4.5%Added
Artal Group S.A.412,082$33.0M1.96%+12,082+3.0%Added
Nicholas Investment Partners, LP374,718$30.0M2.28%+107,629+40.3%Added
Braidwell LP348,036$27.9M0.92%−10,020−2.8%Reduced
Deerfield Management Company, L.P. (Series C)311,949$25.0M0.56%+136,949+78.3%Added
Baker Bros. Advisors LP302,716$24.2M0.13%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)286,018$22.9M0.16%−1,523−0.5%Reduced
Goldman Sachs Group Inc257,860$20.6M0.01%+110,259+74.7%Added
JPMorgan Chase & Co238,409$19.1M0.00%+472+0.2%Added
C WorldWide Group Holding A/S225,809$18.1M0.25%00.0%Unchanged
Victory Capital Management Inc212,130$17.0M0.02%−127,201−37.5%Reduced
Northern Trust Corp201,477$16.1M0.00%+189+0.1%Added
First Light Asset Management, LLC195,980$15.7M1.41%−277,711−58.6%Reduced
Charles Schwab Investment Management Inc159,889$12.8M0.00%−726−0.5%Reduced
ExodusPoint Capital Management, LP136,141$10.9M0.12%+30,380+28.7%Added
Morgan Stanley126,825$10.2M0.00%+60,774+92.0%Added
S Squared Technology, LLC108,215$8.66M5.14%00.0%Unchanged
Citadel Advisors LLC107,325$8.59M0.01%+54,649+103.7%Added
Handelsbanken Fonder AB105,200$8.42M0.05%00.0%Unchanged
Verition Fund Management LLC93,644$7.50M0.12%+13,083+16.2%Added
Bank of America Corp92,887$7.44M0.00%+24,844+36.5%Added
Soleus Capital Management, L.P.85,179$6.82M0.84%−103,038−54.7%Reduced
Integral Health Asset Management, LLC85,000$6.81M1.41%−30,000−26.1%Reduced
Candriam Luxembourg S.C.A.92,000$6.78M0.05%+92,000New
Bank of New York Mellon Corp79,563$6.37M0.00%−2,533−3.1%Reduced
Rafferty Asset Management, LLC61,524$4.93M0.03%−101−0.2%Reduced
International Biotechnology Trust PLC61,000$4.88M1.36%+16,000+35.6%Added
Driehaus Capital Management LLC53,932$4.32M0.06%+53,932New
Nuveen Asset Management, LLC52,931$4.24M0.00%−4,481−7.8%Reduced
Invesco Ltd.51,580$4.13M0.00%+23,537+83.9%Added
Citigroup Inc50,585$4.05M0.01%+21,825+75.9%Added
Norges Bank48,101$3.85M0.00%+25,018+108.4%Added
Hennion & Walsh Asset Management, Inc.45,235$3.62M0.22%+32+0.1%Added
Balyasny Asset Management LLC41,135$3.29M0.01%+32,759+391.1%Added
Swiss National Bank38,900$3.11M0.00%−4,500−10.4%Reduced
CWM, LLC35,165$2.81M0.02%−1,965−5.3%Reduced
Silverarc Capital Management, LLC34,014$2.72M1.22%−24,521−41.9%Reduced
Voya Investment Management LLC33,154$2.65M0.00%−29,455−47.0%Reduced
Rhumbline Advisers32,469$2.60M0.00%+635+2.0%Added
State of New Jersey Common Pension Fund D29,901$2.39M0.01%00.0%Unchanged
Barclays PLC29,893$2.39M0.00%−6,455−17.8%Reduced
DekaBank Deutsche Girozentrale30,300$2.35M0.01%00.0%Unchanged
UBS Group AG28,128$2.25M0.00%−14,495−34.0%Reduced
Susquehanna International Group, LLP26,119$2.09M0.00%+17,927+218.8%Added
Alliancebernstein L.P.26,100$2.09M0.00%00.0%Unchanged
Kennedy Capital Management, Inc.25,807$2.07M0.06%−13−0.1%Reduced
Mutual of America Capital Management LLC25,551$2.05M0.02%−1,177−4.4%Reduced
BNP Paribas Arbitrage, SA25,411$2.03M0.00%+12,607+98.5%Added
EAM Investors, LLC24,727$1.98M0.39%−8,518−25.6%Reduced
New York State Common Retirement Fund24,441$1.96M0.00%−4,698−16.1%Reduced
Jane Street Group, LLC24,106$1.93M0.00%+24,106New
California State Teachers Retirement System23,770$1.90M0.00%−366−1.5%Reduced
Russell Investments Group, Ltd.22,612$1.81M0.00%+22,612New
EFG Asset Management (North America) Corp.20,849$1.67M0.37%−1,167−5.3%Reduced
Bellevue Group AG18,300$1.47M0.02%00.0%Unchanged
Wells Fargo & Company18,185$1.46M0.00%+13,915+325.9%Added
Deutsche Bank AG17,333$1.39M0.00%+3,917+29.2%Added
HighMark Wealth Management LLC17,185$1.38M1.07%00.0%Unchanged
Alps Advisors Inc16,977$1.36M0.01%−467−2.7%Reduced
UBS Asset Management Americas Inc16,793$1.34M0.00%+1,322+8.5%Added
State of Wisconsin Investment Board16,571$1.33M0.00%−968−5.5%Reduced
Parallel Advisors, LLC16,105$1.29M0.04%−17−0.1%Reduced
Ergoteles LLC15,781$1.26M0.05%+1,673+11.9%Added
Martingale Asset Management L P13,608$1.09M0.02%00.0%Unchanged
SEI Investments Co12,952$1.04M0.00%−3,558−21.6%Reduced
Vontobel Holding Ltd.12,905$1.03M0.01%−1,775−12.1%Reduced
Mirae Asset Global Investments Co., Ltd.12,512$1.00M0.00%+2,311+22.7%Added
Profund Advisors LLC11,581$927.2K0.06%+11,581New
Calamos Advisors LLC11,521$922.4K0.00%+11,521New
MetLife Investment Management11,181$895.1K0.01%00.0%Unchanged
HighVista Strategies LLC11,058$885.3K0.72%00.0%Unchanged
Legato Capital Management LLC10,940$875.9K0.16%00.0%Unchanged
Price T Rowe Associates Inc10,610$850.0K0.00%+688+6.9%Added
American International Group, Inc.10,296$824.3K0.01%+204+2.0%Added
Legal & General Group Plc9,249$740.5K0.00%+2,129+29.9%Added
Janus Henderson Group PLC8,811$705.8K0.00%+4,287+94.8%Added
Privium Fund Management B.V.8,680$694.9K0.23%00.0%Unchanged
Marshall Wace, LLP8,571$686.2K0.00%−3,629−29.7%Reduced
Manufacturers Life Insurance Company, The8,521$682.2K0.00%+36+0.4%Added
Public Employees Retirement Association of Colorado7,818$626.0K0.00%00.0%Unchanged
Allianz Asset Management GmbH7,600$608.5K0.00%−4,800−38.7%Reduced
State Board of Administration of Florida Retirement System7,307$585.0K0.00%00.0%Unchanged
Jacob Asset Management of New York LLC7,266$581.7K0.68%+329+4.7%Added
Quantum Private Wealth, LLC7,205$576.8K0.31%00.0%Unchanged
Blair William & Co7,057$565.0K0.00%+100+1.4%Added
Connor, Clark & Lunn Investment Management Ltd.6,990$559.6K0.00%−9,601−57.9%Reduced
Harbor Capital Advisors, Inc.6,383$511.0K0.15%−2,118−24.9%Reduced