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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Krystal Biotech, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
113
+2 vs. Q2 2021
Shares held
16.3M
+511.4K (+3.2%) vs. Q2 2021
Total value
$850.7M
−$222.4M (−20.7%) vs. Q2 2021
New holders
12
45 more added
Sold out
10
33 more reduced

2 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 113 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ3 2021: $850.7M
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q2 2021.

Institutions holding KRYS in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Redmile Group, LLC1,982,432$103.5M1.81%−89,700−4.3%Reduced
FMR LLC1,902,405$99.3M0.01%+134,488+7.6%Added
BlackRock Inc.1,541,386$80.5M0.00%+9,040+0.6%Added
Lord, Abbett & Co. LLC1,067,158$55.7M0.13%−124,422−10.4%Reduced
Vanguard Group Inc888,658$46.4M0.00%+42,303+5.0%Added
Credit Suisse AG771,954$40.3M0.03%+5,629+0.7%Added
Frazier Management LLC771,250$40.3M3.22%−16,626−2.1%Reduced
State Street Corp737,053$38.5M0.00%+24,056+3.4%Added
Pictet Asset Management SA637,492$33.3M0.04%+637,492New
First Light Asset Management, LLC633,481$33.1M2.18%+106,831+20.3%Added
Baker Bros. Advisors LP607,735$31.7M0.14%00.0%Unchanged
Point72 Asset Management, L.P.534,700$27.9M0.13%+193,800+56.8%Added
Artal Group S.A.500,000$26.1M0.64%00.0%Unchanged
Geode Capital Management, LLC317,608$16.6M0.00%−2,568−0.8%Reduced
Nicholas Investment Partners, LP256,875$13.4M0.98%−56,579−18.1%Reduced
Hood River Capital Management LLC225,901$11.8M0.36%−8,866−3.8%Reduced
JPMorgan Chase & Co224,419$11.7M0.00%−186,462−45.4%Reduced
C WorldWide Group Holding A/S185,809$9.70M0.10%00.0%Unchanged
Northern Trust Corp181,434$9.47M0.00%−7,121−3.8%Reduced
Dimensional Fund Advisors LP163,864$8.56M0.00%−49,848−23.3%Reduced
Franklin Resources Inc140,004$7.31M0.00%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)133,001$6.94M0.04%+6,709+5.3%Added
Soleus Capital Management, L.P.125,529$6.55M1.02%+58,000+85.9%Added
Charles Schwab Investment Management Inc125,384$6.55M0.00%+3,312+2.7%Added
Blair William & Co93,138$4.86M0.02%+34,383+58.5%Added
Handelsbanken Fonder AB90,000$4.70M0.02%00.0%Unchanged
S Squared Technology, LLC85,215$4.45M2.02%00.0%Unchanged
Nuveen Asset Management, LLC82,300$4.30M0.00%+14,090+20.7%Added
Bank of New York Mellon Corp76,429$3.99M0.00%+5,799+8.2%Added
Acuta Capital Partners, LLC72,551$3.79M1.35%+72,551New
Verition Fund Management LLC66,045$3.45M0.05%+47,464+255.4%Added
Voya Investment Management LLC56,235$2.94M0.01%−4,280−7.1%Reduced
SG Americas Securities, LLC52,182$2.72M0.01%+16,141+44.8%Added
Neuberger Berman Group LLC45,246$2.35M0.00%+583+1.3%Added
ACT Capital Management, LLC40,000$2.09M1.08%+20,925+109.7%Added
Ensign Peak Advisors, Inc34,596$1.81M0.00%+34,596New
Renaissance Technologies LLC33,300$1.74M0.00%+33,300New
Morgan Stanley33,234$1.74M0.00%−10,217−23.5%Reduced
Swiss National Bank31,800$1.66M0.00%+400+1.3%Added
Citadel Advisors LLC31,003$1.62M0.00%+31,003New
Mutual of America Capital Management LLC30,518$1.59M0.02%−438−1.4%Reduced
Citigroup Inc29,962$1.56M0.00%−19,413−39.3%Reduced
Alps Advisors Inc27,213$1.42M0.01%−2,028−6.9%Reduced
New York State Common Retirement Fund26,159$1.37M0.00%+161+0.6%Added
Marshall Wace, LLP25,655$1.34M0.01%+25,655New
Jacob Asset Management of New York LLC25,044$1.31M0.48%+8,144+48.2%Added
Millennium Management LLC24,810$1.29M0.00%+24,810New
State of Wisconsin Investment Board23,400$1.22M0.00%+4,500+23.8%Added
UBS Group AG23,323$1.22M0.00%+21,315+1,061.5%Added
Rafferty Asset Management, LLC23,254$1.21M0.01%+892+4.0%Added
Endurant Capital Management LP22,938$1.20M0.36%+22,938New
Royce & Associates LP22,000$1.15M0.01%00.0%Unchanged
Rhumbline Advisers21,544$1.13M0.00%+860+4.2%Added
California State Teachers Retirement System21,462$1.12M0.00%−3,280−13.3%Reduced
Vontobel Holding Ltd.21,398$1.12M0.01%−2,749−11.4%Reduced
Goldman Sachs Group Inc21,325$1.11M0.00%−114,533−84.3%Reduced
Alliancebernstein L.P.20,700$1.08M0.00%00.0%Unchanged
HighMark Wealth Management LLC17,376$907.0K0.67%+99+0.6%Added
Deutsche Bank AG14,355$749.0K0.00%−335−2.3%Reduced
D. E. Shaw & Co., Inc.13,571$709.0K0.00%+6,331+87.4%Added
Martingale Asset Management L P13,406$700.0K0.01%+6,900+106.1%Added
Squarepoint Ops LLC12,885$673.0K0.00%+8,384+186.3%Added
Barclays PLC12,700$663.0K0.00%+9,334+277.3%Added
Susquehanna International Group, LLP12,456$650.0K0.00%+4,855+63.9%Added
Two Sigma Investments, LP10,683$558.0K0.00%+10,683New
American International Group, Inc.9,815$512.0K0.00%−234−2.3%Reduced
Manufacturers Life Insurance Company, The9,537$498.0K0.00%−775−7.5%Reduced
State Board of Administration of Florida Retirement System8,777$458.0K0.00%00.0%Unchanged
UBS Asset Management Americas Inc8,705$454.5K0.00%00.0%Unchanged
DekaBank Deutsche Girozentrale8,600$453.0K0.00%00.0%Unchanged
Invesco Ltd.8,136$425.0K0.00%+931+12.9%Added
Federated Hermes, Inc.8,111$423.0K0.00%−145,503−94.7%Reduced
Qube Research & Technologies Ltd7,292$381.0K0.00%+1,307+21.8%Added
Bank of America Corp7,110$370.0K0.00%−1,100−13.4%Reduced
ProShare Advisors LLC7,041$368.0K0.00%−1,600−18.5%Reduced
SEI Investments Co6,978$364.0K0.00%−133−1.9%Reduced
Simplex Trading, LLC5,025$360.0K0.01%−500−9.0%Reduced
MetLife Investment Management6,648$347.1K0.00%00.0%Unchanged
Taylor Wealth Management Partners6,615$345.0K0.12%00.0%Unchanged
J. Goldman & Co LP6,300$329.0K0.03%−4,651−42.5%Reduced
Parametric Portfolio Associates LLC5,922$309.0K0.00%−1,579−21.1%Reduced
Wells Fargo & Company5,677$296.0K0.00%+5,472+2,669.3%Added
Legal & General Group Plc5,595$293.0K0.00%+2,816+101.3%Added
Parallel Advisors, LLC5,454$285.0K0.01%00.0%Unchanged
Metropolitan Life Insurance Co4,786$249.9K0.00%+91+1.9%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.4,730$247.0K0.00%+129+2.8%Added
Principal Financial Group Inc4,356$227.0K0.00%−704−13.9%Reduced
Price T Rowe Associates Inc4,219$220.0K0.00%00.0%Unchanged
Truist Financial Corp4,000$209.0K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC3,960$207.0K0.00%+3,960New
BNP Paribas Arbitrage, SA3,929$205.1K0.00%+3,202+440.4%Added
Arizona State Retirement System3,931$205.0K0.00%+58+1.5%Added
STRS Ohio3,900$203.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC3,288$172.0K0.08%−167−4.8%Reduced
Liberty One Investment Management, LLC2,697$141.0K0.02%−72−2.6%Reduced
Tower Research Capital LLC (TRC)2,410$126.0K0.00%+558+30.1%Added
Point72 Hong Kong Ltd2,276$119.0K0.01%+2,232+5,072.7%Added
KBC Group NV1,975$103.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.1,406$73.0K0.00%00.0%Unchanged
Lazard Asset Management LLC1,051$54.0K0.00%−522−33.2%Reduced