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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Krystal Biotech, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
283
+40 vs. Q2 2024
Shares held
28.3M
+3.70M (+15.0%) vs. Q2 2024
Total value
$5.15B
+$633.9M (+14.0%) vs. Q2 2024
New holders
55
106 more added
Sold out
15
89 more reduced

2 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 283 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ3 2024: $5.15B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q2 2024.

Institutions holding KRYS in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC4,292,881$781.4M0.05%+9,115+0.2%Added
BlackRock, Inc.3,993,123$726.9M0.02%+3,993,123New
Vanguard Group Inc2,849,744$518.7M0.01%−19,392−0.7%Reduced
Avoro Capital Advisors LLC2,622,222$477.3M6.96%+189,222+7.8%Added
State Street Corp1,452,811$264.5M0.01%+119,936+9.0%Added
Frazier Life Sciences Management, L.P.988,460$179.9M7.21%00.0%Unchanged
Capital World Investors879,083$160.0M0.02%+925+0.1%Added
Redmile Group, LLC810,245$147.5M8.69%−210,833−20.6%Reduced
Dimensional Fund Advisors LP600,261$109.3M0.03%+19,809+3.4%Added
Geode Capital Management, LLC591,631$107.7M0.01%+11,411+2.0%Added
Hood River Capital Management LLC502,104$91.4M1.48%−18,989−3.6%Reduced
Price T Rowe Associates Inc438,259$79.8M0.01%−161,886−27.0%Reduced
Jennison Associates LLC410,057$74.6M0.05%−110,333−21.2%Reduced
Invesco Ltd.365,551$66.5M0.01%+90,474+32.9%Added
Nuveen Asset Management, LLC311,855$56.8M0.02%−24,315−7.2%Reduced
Goldman Sachs Group Inc301,354$54.9M0.01%−120,977−28.6%Reduced
Lord, Abbett & Co. LLC284,159$51.7M0.16%−108,079−27.6%Reduced
Morgan Stanley275,804$50.2M0.00%−42,523−13.4%Reduced
Norges Bank244,097$44.4M0.01%+232,757+2,052.5%Added
Franklin Resources Inc243,760$43.8M0.01%+62,178+34.2%Added
Charles Schwab Investment Management Inc240,216$43.7M0.01%+19,777+9.0%Added
Northern Trust Corp238,691$43.4M0.01%+20,230+9.3%Added
UBS Asset Management Americas Inc224,945$40.9M0.01%−26,817−10.7%Reduced
Soleus Capital Management, L.P.216,979$39.5M3.28%+90,979+72.2%Added
Woodline Partners LP179,815$32.7M0.28%−112,103−38.4%Reduced
Bank of New York Mellon Corp171,653$31.2M0.01%−22,114−11.4%Reduced
Baker Bros. Advisors LP169,934$30.9M0.32%00.0%Unchanged
Braidwell LP168,691$30.7M0.87%+61,512+57.4%Added
Driehaus Capital Management LLC163,304$29.7M0.26%+44,558+37.5%Added
Segall Bryant & Hamill, LLC157,144$28.6M0.39%+122,407+352.4%Added
C WorldWide Group Holding A/S135,809$24.7M0.26%00.0%Unchanged
JPMorgan Chase & Co127,901$23.3M0.00%−35,923−21.9%Reduced
Skandinaviska Enskilda Banken AB (publ)126,082$23.0M0.11%−65,433−34.2%Reduced
Principal Financial Group Inc119,726$21.8M0.01%−3,743−3.0%Reduced
Pictet Asset Management Holding SA115,350$21.0M0.02%−22,083−16.1%Reduced
TimesSquare Capital Management, LLC114,222$20.8M0.31%+31,183+37.6%Added
Allspring Global Investments Holdings, LLC111,705$20.3M0.03%−64,741−36.7%Reduced
Bank of America Corp104,654$19.1M0.00%+11,025+11.8%Added
Victory Capital Management Inc98,285$17.9M0.02%−45,580−31.7%Reduced
Eventide Asset Management, LLC95,781$17.4M0.30%−40,704−29.8%Reduced
Handelsbanken Fonder AB94,700$17.2M0.07%−11,800−11.1%Reduced
Ameriprise Financial Inc89,749$16.3M0.00%−12,247−12.0%Reduced
S Squared Technology, LLC75,215$13.7M5.84%−10,000−11.7%Reduced
Decheng Capital LLC71,772$13.1M3.09%+6,000+9.1%Added
Voya Investment Management LLC70,578$12.8M0.01%−4,174−5.6%Reduced
Rhumbline Advisers70,309$12.8M0.01%−1,376−1.9%Reduced
Eagle Asset Management Inc63,602$12.7M0.06%−12,657−16.6%Reduced
First Turn Management, LLC67,942$12.4M1.96%−41,280−37.8%Reduced
Legal & General Group Plc66,255$12.1M0.00%+1,666+2.6%Added
Barclays PLC56,540$10.3M0.00%+37,452+196.2%Added
Rock Springs Capital Management LP55,861$10.2M0.33%−49,708−47.1%Reduced
Public Sector Pension Investment Board53,656$9.77M0.05%−1,000−1.8%Reduced
CI Private Wealth, LLC47,687$8.68M0.01%−17,313−26.6%Reduced
Millennium Management LLC47,623$8.67M0.01%+45,053+1,753.0%Added
Oberweis Asset Management Inc46,800$8.52M0.44%+4,200+9.9%Added
Rafferty Asset Management, LLC45,840$8.34M0.03%+4,040+9.7%Added
Standard Life Aberdeen plc43,054$7.84M0.01%−318−0.7%Reduced
First Trust Advisors LP39,411$7.17M0.01%+39,411New
Scout Investments, Inc.40,100$7.17M0.19%−6,453−13.9%Reduced
Swiss National Bank39,100$7.12M0.00%+2,900+8.0%Added
Prudential Financial Inc37,939$6.91M0.01%−8,599−18.5%Reduced
Janney Montgomery Scott LLC37,047$6.74M0.02%+5,415+17.1%Added
Palisades Investment Partners, LLC37,043$6.74M2.94%+2,356+6.8%Added
Mutual of America Capital Management LLC36,566$6.66M0.07%−758−2.0%Reduced
UBS Group AG36,329$6.61M0.00%+7,773+27.2%Added
GW&K Investment Management, LLC36,029$6.56M0.06%−1,097−3.0%Reduced
Citigroup Inc35,084$6.39M0.01%+13,874+65.4%Added
SEI Investments Co34,249$6.23M0.01%−5,866−14.6%Reduced
TD Asset Management Inc33,480$5.93M0.01%−24,600−42.4%Reduced
Edgestream Partners, L.P.32,257$5.87M0.26%+32,257New
Manufacturers Life Insurance Company, The31,225$5.68M0.00%−9,790−23.9%Reduced
Alliancebernstein L.P.29,720$5.41M0.00%00.0%Unchanged
EAM Global Investors LLC28,976$5.27M1.06%+133+0.5%Added
Man Group plc27,939$5.09M0.01%−41,311−59.7%Reduced
Castleark Management LLC27,290$4.97M0.20%−990−3.5%Reduced
Great West Life Assurance Co26,776$4.87M0.01%−597−2.2%Reduced
New York State Common Retirement Fund25,863$4.71M0.01%−2,518−8.9%Reduced
OrbiMed Advisors LLC23,500$4.28M0.08%−6,466−21.6%Reduced
State of Wisconsin Investment Board23,068$4.20M0.01%−2,242−8.9%Reduced
Alps Advisors Inc22,372$4.07M0.03%+102+0.5%Added
Thrivent Financial for Lutherans19,854$3.61M0.01%−771−3.7%Reduced
California State Teachers Retirement System19,261$3.51M0.00%+836+4.5%Added
Nicholas Investment Partners, LP18,807$3.42M0.31%+1,480+8.5%Added
Jane Street Group, LLC18,181$3.31M0.01%−59,651−76.6%Reduced
Erste Asset Management GmbH18,200$3.22M0.04%00.0%Unchanged
Rhenman & Partners Asset Management AB17,000$3.09M0.25%−2,000−10.5%Reduced
Fiera Capital Corp16,200$2.95M0.01%−80.0%Reduced
Verition Fund Management LLC16,000$2.91M0.02%−1,989−11.1%Reduced
New York State Teachers Retirement System15,879$2.89M0.01%+979+6.6%Added
Squarepoint Ops LLC15,706$2.86M0.01%+13,298+552.2%Added
Deutsche Bank AG15,611$2.84M0.00%+3,341+27.2%Added
Mirae Asset Global ETFs Holdings Ltd.15,386$2.79M0.01%+2,792+22.2%Added
DekaBank Deutsche Girozentrale15,503$2.72M0.01%00.0%Unchanged
State of Alaska, Department of Revenue14,428$2.63M0.03%−159−1.1%Reduced
Renaissance Technologies LLC14,400$2.62M0.00%+14,400New
MetLife Investment Management14,317$2.61M0.01%00.0%Unchanged
Corebridge Financial, Inc.14,257$2.60M0.01%−133−0.9%Reduced
Wells Fargo & Company13,956$2.54M0.00%−534−3.7%Reduced
Hennion & Walsh Asset Management, Inc.13,910$2.53M0.12%−7,740−35.8%Reduced
CWM, LLC13,846$2.52M0.01%−1,772−11.3%Reduced