Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 154
- +8 vs. Q3 2022
- Shares held
- 20.9M
- +147.3K (+0.7%) vs. Q3 2022
- Total value
- $1.66B
- +$208.7M (+14.4%) vs. Q3 2022
- New holders
- 18
- 62 more added
- Sold out
- 10
- 50 more reduced
2 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 2,108,853 | $167.1M | 0.02% | +2,419+0.1% | Added |
| Redmile Group, LLC | 1,896,645 | $150.3M | 6.15% | −2,900−0.2% | Reduced |
| BlackRock Inc. | 1,699,596 | $134.6M | 0.00% | +134,291+8.6% | Added |
| Avoro Capital Advisors LLC | 1,410,000 | $111.7M | 1.67% | +135,000+10.6% | Added |
| Lord, Abbett & Co. LLC | 1,278,022 | $101.2M | 0.36% | +66,081+5.5% | Added |
| Vanguard Group Inc | 1,188,110 | $94.1M | 0.00% | +91,978+8.4% | Added |
| State Street Corp | 1,038,983 | $82.3M | 0.00% | +44,839+4.5% | Added |
| Frazier Life Sciences Management, L.P. | 999,737 | $79.2M | 4.92% | −18,651−1.8% | Reduced |
| Credit Suisse AG | 682,880 | $54.1M | 0.06% | +4,410+0.6% | Added |
| Pictet Asset Management SA | 625,979 | $49.6M | 0.07% | −98,223−13.6% | Reduced |
| Point72 Asset Management, L.P. | 556,252 | $44.1M | 0.17% | −702,253−55.8% | Reduced |
| First Light Asset Management, LLC | 473,691 | $37.5M | 3.48% | −18,864−3.8% | Reduced |
| Hood River Capital Management LLC | 426,879 | $33.8M | 1.23% | +10,123+2.4% | Added |
| Geode Capital Management, LLC | 412,127 | $32.6M | 0.00% | +12,865+3.2% | Added |
| Artal Group S.A. | 400,000 | $31.7M | 1.83% | −100,000−20.0% | Reduced |
| Dimensional Fund Advisors LP | 389,285 | $30.8M | 0.01% | +30,448+8.5% | Added |
| Braidwell LP | 358,056 | $28.4M | 0.95% | +358,056 | New |
| Victory Capital Management Inc | 339,331 | $26.9M | 0.03% | +35,732+11.8% | Added |
| Baker Bros. Advisors LP | 302,716 | $24.0M | 0.14% | −119,469−28.3% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 287,541 | $22.8M | 0.17% | −10,069−3.4% | Reduced |
| Nicholas Investment Partners, LP | 267,089 | $21.2M | 1.85% | +45,063+20.3% | Added |
| JPMorgan Chase & Co | 237,937 | $18.8M | 0.00% | −4,756−2.0% | Reduced |
| C WorldWide Group Holding A/S | 225,809 | $17.9M | 0.24% | 00.0% | Unchanged |
| Northern Trust Corp | 201,288 | $15.9M | 0.00% | −950−0.5% | Reduced |
| Soleus Capital Management, L.P. | 188,217 | $14.9M | 2.14% | −19,115−9.2% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 175,000 | $13.9M | 0.29% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 160,615 | $12.7M | 0.00% | +4,344+2.8% | Added |
| Goldman Sachs Group Inc | 147,601 | $11.7M | 0.00% | +5,216+3.7% | Added |
| Integral Health Asset Management, LLC | 115,000 | $9.11M | 2.05% | +25,000+27.8% | Added |
| S Squared Technology, LLC | 108,215 | $8.57M | 5.80% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 105,761 | $8.38M | 0.13% | +40,975+63.2% | Added |
| Handelsbanken Fonder AB | 105,200 | $8.33M | 0.05% | +300+0.3% | Added |
| Rubric Capital Management LP | 92,609 | $7.34M | 0.32% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 82,096 | $6.50M | 0.00% | −2,696−3.2% | Reduced |
| Verition Fund Management LLC | 80,561 | $6.38M | 0.12% | +12,909+19.1% | Added |
| Bank of America Corp | 68,043 | $5.39M | 0.00% | +26,679+64.5% | Added |
| Morgan Stanley | 66,051 | $5.23M | 0.00% | +18,738+39.6% | Added |
| Voya Investment Management LLC | 62,609 | $4.96M | 0.01% | −1,577−2.5% | Reduced |
| Rafferty Asset Management, LLC | 61,625 | $4.88M | 0.04% | +9,369+17.9% | Added |
| Silverarc Capital Management, LLC | 58,535 | $4.64M | 1.60% | +1,890+3.3% | Added |
| Nuveen Asset Management, LLC | 57,412 | $4.55M | 0.00% | −27,913−32.7% | Reduced |
| Monarch Partners Asset Management LLC | 53,905 | $4.27M | 1.26% | +7,411+15.9% | Added |
| Citadel Advisors LLC | 52,676 | $4.17M | 0.00% | +43,938+502.8% | Added |
| Hennion & Walsh Asset Management, Inc. | 45,203 | $3.58M | 0.22% | +4,547+11.2% | Added |
| International Biotechnology Trust PLC | 45,000 | $3.56M | 1.10% | 00.0% | Unchanged |
| Swiss National Bank | 43,400 | $3.44M | 0.00% | +800+1.9% | Added |
| UBS Group AG | 42,623 | $3.38M | 0.00% | +42,459+25,889.6% | Added |
| SG Americas Securities, LLC | 38,774 | $3.07M | 0.05% | +36,434+1,557.0% | Added |
| CWM, LLC | 37,130 | $2.94M | 0.02% | −6,254−14.4% | Reduced |
| Barclays PLC | 36,348 | $2.88M | 0.00% | +3,217+9.7% | Added |
| EAM Investors, LLC | 33,245 | $2.63M | 0.55% | −194−0.6% | Reduced |
| Rhumbline Advisers | 31,834 | $2.52M | 0.00% | +711+2.3% | Added |
| DekaBank Deutsche Girozentrale | 30,300 | $2.38M | 0.01% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 29,901 | $2.37M | 0.01% | −3,561−10.6% | Reduced |
| New York State Common Retirement Fund | 29,139 | $2.31M | 0.00% | −80.0% | Reduced |
| Citigroup Inc | 28,760 | $2.28M | 0.00% | −21,063−42.3% | Reduced |
| Invesco Ltd. | 28,043 | $2.22M | 0.00% | −23,565−45.7% | Reduced |
| Mutual of America Capital Management LLC | 26,728 | $2.12M | 0.03% | +365+1.4% | Added |
| Alliancebernstein L.P. | 26,100 | $2.07M | 0.00% | +600+2.4% | Added |
| Kennedy Capital Management, Inc. | 25,820 | $2.05M | 0.06% | −1,465−5.4% | Reduced |
| California State Teachers Retirement System | 24,136 | $1.91M | 0.00% | +270+1.1% | Added |
| Norges Bank | 23,083 | $1.83M | 0.00% | +9,557+70.7% | Added |
| EFG Asset Management (North America) Corp. | 22,016 | $1.76M | 0.40% | +4,315+24.4% | Added |
| Bank of Montreal | 21,698 | $1.76M | 0.00% | +60+0.3% | Added |
| EAM Global Investors LLC | 21,605 | $1.71M | 0.44% | 00.0% | Unchanged |
| J. Goldman & Co LP | 19,319 | $1.53M | 0.11% | +9,392+94.6% | Added |
| Qube Research & Technologies Ltd | 19,224 | $1.52M | 0.01% | +19,224 | New |
| Bellevue Group AG | 18,300 | $1.45M | 0.02% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 17,539 | $1.39M | 0.00% | −208−1.2% | Reduced |
| Alps Advisors Inc | 17,444 | $1.38M | 0.01% | +3,403+24.2% | Added |
| HighMark Wealth Management LLC | 17,185 | $1.36M | 1.03% | 00.0% | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. | 16,591 | $1.31M | 0.01% | −7,889−32.2% | Reduced |
| SEI Investments Co | 16,510 | $1.31M | 0.00% | −380−2.2% | Reduced |
| Parallel Advisors, LLC | 16,122 | $1.28M | 0.06% | −5,236−24.5% | Reduced |
| UBS Asset Management Americas Inc | 15,471 | $1.23M | 0.00% | −701−4.3% | Reduced |
| Millennium Management LLC | 15,123 | $1.20M | 0.00% | +15,123 | New |
| Vontobel Holding Ltd. | 14,680 | $1.16M | 0.01% | −3,188−17.8% | Reduced |
| Ergoteles LLC | 14,108 | $1.12M | 0.04% | +14,108 | New |
| Martingale Asset Management L P | 13,608 | $1.08M | 0.02% | +9,005+195.6% | Added |
| Deutsche Bank AG | 13,416 | $1.06M | 0.00% | +1,165+9.5% | Added |
| BNP Paribas Arbitrage, SA | 12,804 | $1.01M | 0.00% | −9,076−41.5% | Reduced |
| Allianz Asset Management GmbH | 12,400 | $982.3K | 0.00% | −50−0.4% | Reduced |
| Marshall Wace, LLP | 12,200 | $966.5K | 0.00% | +12,200 | New |
| MetLife Investment Management | 11,181 | $885.8K | 0.01% | 00.0% | Unchanged |
| HighVista Strategies LLC | 11,058 | $876.0K | 0.52% | +4,023+57.2% | Added |
| Legato Capital Management LLC | 10,940 | $866.7K | 0.17% | +10,940 | New |
| Advisory Research Inc | 10,354 | $820.2K | 0.08% | −465−4.3% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 10,201 | $808.1K | 0.00% | +10,201 | New |
| American International Group, Inc. | 10,092 | $799.5K | 0.01% | −37−0.4% | Reduced |
| Price T Rowe Associates Inc | 9,922 | $786.0K | 0.00% | −272−2.7% | Reduced |
| Privium Fund Management B.V. | 8,680 | $693.5K | 0.26% | +1,418+19.5% | Added |
| Harbor Capital Advisors, Inc. | 8,501 | $673.4K | 0.67% | −3,276−27.8% | Reduced |
| Manufacturers Life Insurance Company, The | 8,485 | $672.2K | 0.00% | +150+1.8% | Added |
| Balyasny Asset Management LLC | 8,376 | $663.5K | 0.00% | +8,376 | New |
| Susquehanna International Group, LLP | 8,192 | $649.0K | 0.00% | −12,058−59.5% | Reduced |
| Public Employees Retirement Association of Colorado | 7,818 | $619.0K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 7,307 | $578.9K | 0.00% | −420−5.4% | Reduced |
| Quantum Private Wealth, LLC | 7,205 | $570.8K | 0.36% | 00.0% | Unchanged |
| Legal & General Group Plc | 7,120 | $564.0K | 0.00% | +155+2.2% | Added |
| Blair William & Co | 6,957 | $551.1K | 0.00% | +580+9.1% | Added |