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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
234
+41 vs. Q4 2023
Shares held
25.2M
+861.0K (+3.5%) vs. Q4 2023
Total value
$4.49B
+$1.46B (+48.4%) vs. Q4 2023
New holders
66
62 more added
Sold out
25
83 more reduced

1 institution that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 234 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ1 2024: $4.49B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2023.

Institutions holding KRYS in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC4,243,892$755.1M0.05%+1,857,994+77.9%Added
Avoro Capital Advisors LLC2,555,555$454.7M5.30%−10,000−0.4%Reduced
Vanguard Group Inc2,432,779$432.9M0.01%−2,995−0.1%Reduced
BlackRock Inc.1,805,379$321.2M0.01%−4,168−0.2%Reduced
Redmile Group, LLC1,508,250$268.4M9.85%−224,939−13.0%Reduced
Frazier Life Sciences Management, L.P.988,460$175.9M7.42%00.0%Unchanged
State Street Corp944,547$168.1M0.01%−292,950−23.7%Reduced
Jennison Associates LLC670,735$119.3M0.08%−53,609−7.4%Reduced
Price T Rowe Associates Inc658,618$117.2M0.01%+231,255+54.1%Added
Dimensional Fund Advisors LP572,915$101.9M0.03%+22,109+4.0%Added
Geode Capital Management, LLC525,745$93.6M0.01%+14,499+2.8%Added
Hood River Capital Management LLC495,586$88.2M1.97%+37,073+8.1%Added
Lord, Abbett & Co. LLC492,232$87.6M0.28%−126,226−20.4%Reduced
Goldman Sachs Group Inc434,574$77.3M0.02%+206,521+90.6%Added
Nuveen Asset Management, LLC330,442$58.8M0.02%+14,977+4.7%Added
Credit Suisse AG321,946$57.3M0.06%−152,538−32.1%Reduced
Woodline Partners LP275,455$49.0M0.45%−206,524−42.8%Reduced
Morgan Stanley218,829$38.9M0.00%−100,892−31.6%Reduced
Skandinaviska Enskilda Banken AB (publ)217,747$38.7M0.19%−26,314−10.8%Reduced
Northern Trust Corp205,078$36.5M0.01%−4,121−2.0%Reduced
Charles Schwab Investment Management Inc188,903$33.6M0.01%+3,865+2.1%Added
Braidwell LP177,089$31.5M1.02%−19,111−9.7%Reduced
JPMorgan Chase & Co175,126$31.2M0.00%−38,393−18.0%Reduced
Baker Bros. Advisors LP169,934$30.2M0.38%00.0%Unchanged
Allspring Global Investments Holdings, LLC158,425$28.2M0.04%+99,101+167.1%Added
Pictet Asset Management Holding SA142,960$25.4M0.03%−49,915−25.9%Reduced
Eventide Asset Management, LLC136,485$24.3M0.38%00.0%Unchanged
C WorldWide Group Holding A/S135,809$24.2M0.28%−50,000−26.9%Reduced
Victory Capital Management Inc134,820$24.0M0.02%−38,059−22.0%Reduced
Franklin Resources Inc131,465$23.4M0.01%+104,919+395.2%Added
First Turn Management, LLC130,850$23.3M3.48%−111,335−46.0%Reduced
Balyasny Asset Management LLC124,203$22.1M0.06%−132,401−51.6%Reduced
Driehaus Capital Management LLC110,199$19.6M0.20%−86,187−43.9%Reduced
Handelsbanken Fonder AB105,200$18.7M0.08%−18,000−14.6%Reduced
Rock Springs Capital Management LP103,969$18.5M0.47%00.0%Unchanged
Susquehanna International Group, LLP101,557$18.1M0.03%+93,515+1,162.8%Added
TimesSquare Capital Management, LLC97,161$17.3M0.25%−153,309−61.2%Reduced
Capital World Investors97,147$17.3M0.00%+97,147New
Man Group plc95,858$17.1M0.05%+45,022+88.6%Added
Jane Street Group, LLC93,745$16.7M0.02%+43,127+85.2%Added
S Squared Technology, LLC90,215$16.1M7.37%−20,000−18.1%Reduced
Bank of New York Mellon Corp89,839$16.0M0.00%−8,812−8.9%Reduced
Invesco Ltd.89,628$15.9M0.00%+35,399+65.3%Added
Soleus Capital Management, L.P.84,100$15.0M1.31%+44,100+110.3%Added
D. E. Shaw & Co., Inc.82,027$14.6M0.02%+14,886+22.2%Added
Integral Health Asset Management, LLC80,000$14.2M1.40%−5,000−5.9%Reduced
Bank of America Corp75,844$13.5M0.00%−15,349−16.8%Reduced
TD Asset Management Inc69,162$12.3M0.01%+28,200+68.8%Added
Decheng Capital LLC65,772$11.7M1.57%00.0%Unchanged
Verition Fund Management LLC61,800$11.0M0.11%−34,158−35.6%Reduced
Voya Investment Management LLC60,725$10.8M0.01%+13,128+27.6%Added
Millennium Management LLC56,635$10.1M0.01%+48,114+564.7%Added
Rafferty Asset Management, LLC53,367$9.50M0.04%−30,654−36.5%Reduced
Citigroup Inc52,118$9.27M0.01%+15,552+42.5%Added
UBS Group AG51,028$9.08M0.00%+20,268+65.9%Added
Scout Investments, Inc.50,977$8.98M0.22%+50,977New
Vestal Point Capital, LP45,000$8.01M0.66%+45,000New
Ameriprise Financial Inc43,391$7.72M0.00%+27,452+172.2%Added
Manufacturers Life Insurance Company, The41,298$7.35M0.01%+12,048+41.2%Added
Schroder Investment Management Group39,484$7.03M0.01%−35,461−47.3%Reduced
Standard Life Aberdeen plc39,024$6.94M0.01%+39,024New
Prudential Financial Inc37,845$6.73M0.01%−1,711−4.3%Reduced
GW&K Investment Management, LLC37,528$6.68M0.06%+37,528New
OrbiMed Advisors LLC37,166$6.61M0.13%−66,534−64.2%Reduced
Swiss National Bank36,200$6.44M0.00%+300+0.8%Added
CI Private Wealth, LLC35,972$6.40M0.01%+35,972New
Oberweis Asset Management Inc35,700$6.35M0.46%+35,700New
Mutual of America Capital Management LLC34,189$6.08M0.07%−2,199−6.0%Reduced
SEI Investments Co33,752$6.01M0.01%+18,968+128.3%Added
Hennion & Walsh Asset Management, Inc.33,154$5.90M0.32%+1,756+5.6%Added
Rhumbline Advisers32,099$5.71M0.01%+314+1.0%Added
EAM Global Investors LLC28,842$5.13M1.19%+28,842New
Castleark Management LLC28,520$5.07M0.21%−3,830−11.8%Reduced
Affinity Asset Advisors, LLC26,746$4.76M0.77%+1,746+7.0%Added
EAM Investors, LLC26,435$4.70M0.74%+26,435New
Citadel Advisors LLC25,014$4.45M0.00%+16,815+205.1%Added
Renaissance Technologies LLC24,700$4.39M0.01%+24,700New
CWM, LLC23,850$4.24M0.02%−6,719−22.0%Reduced
Alliancebernstein L.P.23,760$4.23M0.00%−2,140−8.3%Reduced
Barclays PLC21,614$3.85M0.00%−42,565−66.3%Reduced
J. Goldman & Co LP20,963$3.73M0.17%+15,555+287.6%Added
Ensign Peak Advisors, Inc20,917$3.72M0.01%+14,017+203.1%Added
Legal & General Group Plc19,550$3.48M0.00%+458+2.4%Added
Rhenman & Partners Asset Management AB19,000$3.38M0.32%+19,000New
California State Teachers Retirement System18,660$3.32M0.00%−1,109−5.6%Reduced
Eversept Partners, LP18,557$3.30M0.25%−62,241−77.0%Reduced
ExodusPoint Capital Management, LP18,272$3.25M0.04%−24,230−57.0%Reduced
UBS Asset Management Americas Inc18,261$3.25M0.00%−2,165−10.6%Reduced
Erste Asset Management GmbH18,200$3.23M0.04%00.0%Unchanged
New York State Common Retirement Fund18,028$3.21M0.00%+3,035+20.2%Added
Janney Montgomery Scott LLC17,843$3.17M0.01%+17,843New
State of New Jersey Common Pension Fund D17,759$3.16M0.01%−7,045−28.4%Reduced
BNP Paribas Arbitrage, SA16,778$2.99M0.00%−22,294−57.1%Reduced
BCJ Capital Management, LLC16,684$2.97M0.24%+16,684New
State of Wisconsin Investment Board16,215$2.89M0.01%+1,319+8.9%Added
Fiera Capital Corp16,078$2.86M0.01%+178+1.1%Added
DekaBank Deutsche Girozentrale15,503$2.71M0.01%00.0%Unchanged
Exome Asset Management LLC14,700$2.62M2.24%+14,700New
Brevan Howard Capital Management LP14,127$2.51M0.23%+14,127New
Ghost Tree Capital, LLC14,000$2.49M0.80%−36,000−72.0%Reduced