Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 299
- +37 vs. Q4 2024
- Shares held
- 27.6M
- +139.0K (+0.5%) vs. Q4 2024
- Total value
- $4.98B
- +$673.8M (+15.7%) vs. Q4 2024
- New holders
- 64
- 88 more added
- Sold out
- 27
- 112 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 4,320,832 | $779.0M | 0.05% | +6,818+0.2% | Added |
| BlackRock, Inc. | 3,943,165 | $711.0M | 0.02% | −90,707−2.2% | Reduced |
| Vanguard Group Inc | 2,825,282 | $509.4M | 0.01% | −53,169−1.8% | Reduced |
| Avoro Capital Advisors LLC | 2,731,000 | $492.4M | 7.69% | +102,178+3.9% | Added |
| State Street Corp | 1,226,707 | $221.2M | 0.01% | −52,268−4.1% | Reduced |
| Capital World Investors | 954,468 | $172.1M | 0.03% | +75,265+8.6% | Added |
| Redmile Group, LLC | 737,675 | $133.0M | 12.57% | −15,500−2.1% | Reduced |
| Frazier Life Sciences Management, L.P. | 688,460 | $124.1M | 5.67% | −100,000−12.7% | Reduced |
| Geode Capital Management, LLC | 612,353 | $110.4M | 0.01% | +20,757+3.5% | Added |
| UBS Asset Management Americas Inc | 575,506 | $103.8M | 0.03% | +365,304+173.8% | Added |
| Dimensional Fund Advisors LP | 533,919 | $96.3M | 0.02% | −54,680−9.3% | Reduced |
| Hood River Capital Management LLC | 524,644 | $94.6M | 1.61% | +11,918+2.3% | Added |
| Soleus Capital Management, L.P. | 441,758 | $79.6M | 6.25% | +83,379+23.3% | Added |
| Price T Rowe Associates Inc | 410,861 | $74.1M | 0.01% | −98,598−19.4% | Reduced |
| Braidwell LP | 400,744 | $72.3M | 2.54% | +200,244+99.9% | Added |
| Morgan Stanley | 298,205 | $53.8M | 0.00% | +41,930+16.4% | Added |
| Norges Bank | 273,209 | $49.3M | 0.01% | +53,681+24.5% | Added |
| Northern Trust Corp | 259,995 | $46.9M | 0.01% | −2,268−0.9% | Reduced |
| Invesco Ltd. | 254,486 | $45.9M | 0.01% | −20,709−7.5% | Reduced |
| Charles Schwab Investment Management Inc | 250,514 | $45.2M | 0.01% | +7,344+3.0% | Added |
| Nuveen, LLC | 234,180 | $42.2M | 0.01% | +234,180 | New |
| Goldman Sachs Group Inc | 233,640 | $42.1M | 0.01% | −43,535−15.7% | Reduced |
| Woodline Partners LP | 222,043 | $40.0M | 0.26% | +941+0.4% | Added |
| T. Rowe Price Investment Management, Inc. | 185,550 | $33.5M | 0.02% | +185,550 | New |
| Bank of New York Mellon Corp | 169,179 | $30.5M | 0.01% | −167−0.1% | Reduced |
| Lord, Abbett & Co. LLC | 151,225 | $27.3M | 0.10% | −64,403−29.9% | Reduced |
| Segall Bryant & Hamill, LLC | 145,337 | $26.2M | 0.40% | −3,972−2.7% | Reduced |
| TimesSquare Capital Management, LLC | 142,183 | $25.6M | 0.41% | −16,685−10.5% | Reduced |
| 1832 Asset Management L.P. | 136,000 | $24.5M | 0.05% | +136,000 | New |
| Principal Financial Group Inc | 126,337 | $22.8M | 0.01% | +2,884+2.3% | Added |
| JPMorgan Chase & Co | 100,774 | $18.2M | 0.00% | −51,061−33.6% | Reduced |
| S Squared Technology, LLC | 97,215 | $17.5M | 8.97% | +2,000+2.1% | Added |
| Eventide Asset Management, LLC | 95,781 | $17.3M | 0.34% | 00.0% | Unchanged |
| Bank of America Corp | 92,561 | $16.7M | 0.00% | +16,762+22.1% | Added |
| C WorldWide Group Holding A/S | 85,809 | $15.5M | 0.19% | −20,000−18.9% | Reduced |
| Squarepoint Ops LLC | 81,999 | $14.8M | 0.04% | +72,440+757.8% | Added |
| UBS Group AG | 81,119 | $14.6M | 0.00% | −19,012−19.0% | Reduced |
| Public Sector Pension Investment Board | 80,264 | $14.5M | 0.06% | +17,254+27.4% | Added |
| Handelsbanken Fonder AB | 74,300 | $13.4M | 0.06% | −11,000−12.9% | Reduced |
| Citigroup Inc | 73,525 | $13.3M | 0.01% | −26,108−26.2% | Reduced |
| Victory Capital Management Inc | 72,815 | $13.1M | 0.01% | −8,513−10.5% | Reduced |
| Rhumbline Advisers | 68,727 | $12.4M | 0.01% | −409−0.6% | Reduced |
| Legal & General Group Plc | 66,509 | $12.0M | 0.00% | −2,916−4.2% | Reduced |
| Raymond James Financial Inc | 65,961 | $11.9M | 0.00% | −36,100−35.4% | Reduced |
| Pictet Asset Management Holding SA | 65,262 | $11.8M | 0.01% | −46,827−41.8% | Reduced |
| Decheng Capital LLC | 65,000 | $11.7M | 3.29% | −11,772−15.3% | Reduced |
| Voya Investment Management LLC | 64,601 | $11.6M | 0.01% | −10,100−13.5% | Reduced |
| Ameriprise Financial Inc | 60,508 | $10.9M | 0.00% | −52,968−46.7% | Reduced |
| Millennium Management LLC | 60,388 | $10.9M | 0.01% | +41,432+218.6% | Added |
| Integral Health Asset Management, LLC | 60,000 | $10.8M | 1.20% | +5,000+9.1% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 59,978 | $10.8M | 0.05% | −29,069−32.6% | Reduced |
| D. E. Shaw & Co., Inc. | 49,892 | $9.00M | 0.01% | +42,465+571.8% | Added |
| Oberweis Asset Management Inc | 46,800 | $8.44M | 0.42% | 00.0% | Unchanged |
| Janney Montgomery Scott LLC | 45,935 | $8.28M | 0.02% | −6,657−12.7% | Reduced |
| Barclays PLC | 44,997 | $8.11M | 0.00% | −7,432−14.2% | Reduced |
| CI Private Wealth, LLC | 42,127 | $7.60M | 0.01% | −882−2.1% | Reduced |
| Swiss National Bank | 41,800 | $7.54M | 0.01% | −600−1.4% | Reduced |
| Kennedy Capital Management, Inc. | 41,518 | $7.49M | 0.18% | +13,807+49.8% | Added |
| Palisades Investment Partners, LLC | 40,696 | $7.34M | 3.68% | +217+0.5% | Added |
| TD Asset Management Inc | 40,268 | $7.26M | 0.01% | −3,212−7.4% | Reduced |
| Russell Investments Group, Ltd. | 37,781 | $6.81M | 0.01% | +37,336+8,390.1% | Added |
| Standard Life Aberdeen plc | 37,301 | $6.73M | 0.01% | −19,732−34.6% | Reduced |
| Mutual of America Capital Management LLC | 36,431 | $6.57M | 0.08% | −87−0.2% | Reduced |
| GW&K Investment Management, LLC | 34,100 | $6.15M | 0.06% | −830−2.4% | Reduced |
| Susquehanna International Group, LLP | 33,829 | $6.10M | 0.01% | −4,639−12.1% | Reduced |
| Jennison Associates LLC | 33,594 | $6.06M | 0.00% | −269,927−88.9% | Reduced |
| First Trust Advisors LP | 33,125 | $5.97M | 0.01% | +9,956+43.0% | Added |
| Manufacturers Life Insurance Company, The | 32,366 | $5.84M | 0.01% | −2,840−8.1% | Reduced |
| Beacon Harbor Wealth Advisors, Inc. | 32,235 | $5.81M | 1.35% | +32,235 | New |
| Alliancebernstein L.P. | 31,120 | $5.61M | 0.00% | 00.0% | Unchanged |
| Lisanti Capital Growth, LLC | 30,410 | $5.48M | 1.63% | +30,410 | New |
| Prudential Financial Inc | 27,311 | $4.92M | 0.01% | −13,882−33.7% | Reduced |
| Castleark Management LLC | 26,120 | $4.71M | 0.16% | +26,120 | New |
| Los Angeles Capital Management LLC | 24,929 | $4.49M | 0.02% | +15,045+152.2% | Added |
| Great West Life Assurance Co | 24,609 | $4.43M | 0.01% | −2,145−8.0% | Reduced |
| State of Wisconsin Investment Board | 24,183 | $4.36M | 0.01% | −319−1.3% | Reduced |
| Rafferty Asset Management, LLC | 24,161 | $4.36M | 0.02% | −3,040−11.2% | Reduced |
| Jane Street Group, LLC | 23,663 | $4.27M | 0.01% | −12,192−34.0% | Reduced |
| OrbiMed Advisors LLC | 23,500 | $4.24M | 0.10% | 00.0% | Unchanged |
| HealthInvest Partners AB | 23,491 | $4.24M | 1.87% | +14,289+155.3% | Added |
| New York State Common Retirement Fund | 23,382 | $4.22M | 0.01% | 00.0% | Unchanged |
| Deutsche Bank AG | 21,737 | $3.92M | 0.00% | −3,624−14.3% | Reduced |
| California State Teachers Retirement System | 20,126 | $3.63M | 0.00% | −262−1.3% | Reduced |
| Franklin Resources Inc | 19,013 | $3.43M | 0.00% | −165,014−89.7% | Reduced |
| SEI Investments Co | 18,691 | $3.37M | 0.00% | −2,473−11.7% | Reduced |
| Verition Fund Management LLC | 18,625 | $3.36M | 0.02% | −6,277−25.2% | Reduced |
| Schonfeld Strategic Advisors LLC | 18,624 | $3.36M | 0.02% | +11,020+144.9% | Added |
| Thrivent Financial for Lutherans | 18,590 | $3.35M | 0.01% | −973−5.0% | Reduced |
| Erste Asset Management GmbH | 18,200 | $3.35M | 0.04% | 00.0% | Unchanged |
| Rhenman & Partners Asset Management AB | 17,750 | $3.20M | 0.37% | −6,000−25.3% | Reduced |
| EFG Asset Management (North America) Corp. | 17,371 | $3.13M | 0.52% | −343−1.9% | Reduced |
| Marshall Wace, LLP | 17,224 | $3.11M | 0.00% | +6,893+66.7% | Added |
| Wells Fargo & Company | 17,135 | $3.09M | 0.00% | +207+1.2% | Added |
| Fieldview Capital Management, LLC | 16,342 | $2.95M | 0.42% | +16,342 | New |
| New York State Teachers Retirement System | 15,979 | $2.88M | 0.01% | +100+0.6% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 15,893 | $2.87M | 0.01% | +688+4.5% | Added |
| DekaBank Deutsche Girozentrale | 15,503 | $2.82M | 0.01% | 00.0% | Unchanged |
| Fiera Capital Corp | 15,645 | $2.82M | 0.01% | −28−0.2% | Reduced |
| MetLife Investment Management | 14,524 | $2.62M | 0.01% | −473−3.2% | Reduced |
| State of Alaska, Department of Revenue | 14,024 | $2.53M | 0.03% | −399−2.8% | Reduced |