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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
299
+37 vs. Q4 2024
Shares held
27.6M
+139.0K (+0.5%) vs. Q4 2024
Total value
$4.98B
+$673.8M (+15.7%) vs. Q4 2024
New holders
64
88 more added
Sold out
27
112 more reduced

2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 299 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ1 2025: $4.98B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2024.

Institutions holding KRYS in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Hantz Financial Services, Inc.2$00.00%+2New
Abound Wealth Management1$1810.00%−1−50.0%Reduced
TFC Financial Management1$1810.00%+1New
JFS Wealth Advisors, LLC2$3610.00%00.0%Unchanged
Cornerstone Planning Group LLC4$6630.00%+4New
Rakuten Securities, Inc.5$9020.00%−15−75.0%Reduced
Private Wealth Management Group, LLC5$9020.00%00.0%Unchanged
Glen Eagle Advisors, LLC5$9020.00%00.0%Unchanged
Stephens Consulting, LLC5$9020.00%+5New
Kestra Investment Management, LLC5$9020.00%+5New
Principal Securities, Inc.7$1.10K0.00%00.0%Unchanged
Geneos Wealth Management Inc.8$1.44K0.00%+8New
Wolff Wiese Magana LLC8$1.44K0.00%00.0%Unchanged
Ronald Blue Trust, Inc.9$1.62K0.00%+6+200.0%Added
Sound Income Strategies, LLC10$1.80K0.00%00.0%Unchanged
Highline Wealth Partners LLC10$1.80K0.00%+10New
Bare Financial Services, Inc11$1.98K0.00%+11New
NBC Securities, Inc.15$2.00K0.00%+15New
Farmers & Merchants Investments Inc15$2.71K0.00%00.0%Unchanged
Bell Investment Advisors, Inc19$3.43K0.00%−9−32.1%Reduced
Trust Co of Vermont20$3.61K0.00%00.0%Unchanged
Parkside Financial Bank & Trust21$3.79K0.00%+18+600.0%Added
Farther Finance Advisors, LLC23$4.01K0.00%00.0%Unchanged
Clearstead Advisors, LLC24$4.33K0.00%00.0%Unchanged
Allworth Financial LP26$4.40K0.00%+20+333.3%Added
Sterling Capital Management LLC26$4.69K0.00%+1+4.0%Added
GWM Advisors LLC34$6.19K0.00%00.0%Unchanged
Versant Capital Management, Inc37$6.67K0.00%−16−30.2%Reduced
Rothschild Investment LLC46$8.29K0.00%+29+170.6%Added
Federation des caisses Desjardins du Quebec50$9.02K0.00%00.0%Unchanged
Lindbrook Capital, LLC51$9.20K0.00%−7−12.1%Reduced
Massmutual Trust Co FSB52$9.38K0.00%+26+100.0%Added
EverSource Wealth Advisors, LLC55$9.92K0.00%+32+139.1%Added
Quent Capital, LLC59$10.6K0.00%+59New
Rise Advisors, LLC66$11.9K0.01%+66New
Bessemer Group Inc69$12.0K0.00%+15+27.8%Added
SBI Securities Co., Ltd.71$12.8K0.00%−48−40.3%Reduced
Umb Bank N A73$13.2K0.00%+38+108.6%Added
First Horizon Advisors, Inc.78$14.1K0.00%+78New
Daiwa Securities Group Inc.95$17.0K0.00%00.0%Unchanged
Citadel Advisors LLC96$17.3K0.00%−10,919−99.1%Reduced
Signaturefd, LLC130$23.4K0.00%+23+21.5%Added
MAI Capital Management134$24.2K0.00%00.0%Unchanged
Skopos Labs, Inc.141$25.4K0.01%+105+291.7%Added
Key Financial Inc151$27.2K0.01%00.0%Unchanged
Twin Tree Management, LP161$29.0K0.00%+161New
Fifth Third Bancorp171$30.8K0.00%+105+159.1%Added
Huntington National Bank213$38.4K0.00%−366−63.2%Reduced
Bryn Mawr Trust Co225$40.6K0.00%+7+3.2%Added
Caldwell Trust Co250$45.1K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.278$50.1K0.00%−28−9.2%Reduced
Smartleaf Asset Management LLC315$57.9K0.01%+177+128.3%Added
Lazard Asset Management LLC404$72.0K0.00%−72−15.1%Reduced
BI Asset Management Fondsmaeglerselskab A/S408$74.0K0.00%+408New
Coldstream Capital Management Inc556$100.2K0.00%+556New
US Bancorp639$115.2K0.00%−388−37.8%Reduced
GAMMA Investing LLC673$121.3K0.01%+432+179.3%Added
Pacer Advisors, Inc.708$127.7K0.00%−692−49.4%Reduced
Tower Research Capital LLC (TRC)730$131.6K0.00%−6,269−89.6%Reduced
GF Fund Management Co. Ltd.736$132.7K0.00%+132+21.9%Added
Nisa Investment Advisors, LLC920$165.9K0.00%−88−8.7%Reduced
KBC Group NV939$169.0K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.964$177.3K0.00%+6+0.6%Added
Headlands Technologies LLC1,010$182.1K0.02%−625−38.2%Reduced
Brinker Capital Investments, LLC1,160$209.1K0.00%+1,160New
Orion Portfolio Solutions, LLC1,160$209.1K0.00%+1,160New
Magnetar Financial LLC1,175$211.9K0.00%+1,175New
Hilltop Holdings Inc.1,196$215.6K0.01%+1,196New
Empowered Funds, LLC1,211$218.3K0.00%+1,211New
Mount Yale Investment Advisors, LLC1,239$223.4K0.02%+1,239New
Avanza Fonder AB1,260$228.1K0.01%+501+66.0%Added
Oppenheimer Asset Management Inc.1,269$228.8K0.00%+1,269New
Canada Pension Plan Investment Board1,300$234.4K0.00%+1,300New
SG Americas Securities, LLC1,312$237.0K0.00%+1,312New
Shaker Investments LLC1,329$239.6K0.12%+1,329New
Evergreen Capital Management LLC1,348$243.0K0.01%+1,348New
Two Sigma Securities, LLC1,361$245.4K0.04%+1,361New
Transcend Wealth Collective, LLC1,383$249.4K0.02%+1+0.1%Added
Ethic Inc.1,431$249.8K0.01%+1,431New
Mindset Wealth Management, LLC1,450$261.4K0.10%+1,450New
CWM, LLC1,476$266.0K0.00%−6,577−81.7%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,492$269.0K0.00%+125+9.1%Added
Covestor Ltd1,497$270.0K0.18%+789+111.4%Added
Syon Capital LLC1,506$271.5K0.02%+1,506New
Sound View Wealth Advisors Group, LLC1,515$273.2K0.02%+95+6.7%Added
Mackenzie Financial Corp1,532$276.2K0.00%00.0%Unchanged
O'Shaughnessy Asset Management, LLC1,538$277.3K0.00%+1,538New
Royal Bank of Canada1,628$294.0K0.00%+964+145.2%Added
LPL Financial LLC1,660$299.2K0.00%−1,286−43.7%Reduced
Quest Partners LLC1,663$299.8K0.03%−1,357−44.9%Reduced
Argent Trust Co1,692$305.1K0.01%−207−10.9%Reduced
United Services Automobile Association1,661$305.5K0.01%+1,661New
Parallel Advisors, LLC1,731$312.1K0.01%−1,506−46.5%Reduced
DnB Asset Management AS1,779$320.8K0.00%+242+15.7%Added
SIH Partners, LLLP1,815$327.2K0.03%+1,815New
Xponance, Inc.1,873$337.7K0.00%+88+4.9%Added
Alps Advisors Inc1,920$346.2K0.00%+1,920New
JustInvest LLC1,946$350.9K0.01%+546+39.0%Added
Farallon Capital Management, L.L.C.2,000$360.6K0.00%00.0%Unchanged
OmniStar Financial Group, Inc.2,026$365.3K0.29%+2,026New