Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 264
- −15 vs. Q3 2024
- Shares held
- 27.8M
- −399.3K (−1.4%) vs. Q3 2024
- Total value
- $4.35B
- −$775.6M (−15.1%) vs. Q3 2024
- New holders
- 37
- 95 more added
- Sold out
- 52
- 97 more reduced
4 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 4,314,014 | $675.8M | 0.04% | +21,133+0.5% | Added |
| BlackRock, Inc. | 4,033,872 | $631.9M | 0.01% | +40,749+1.0% | Added |
| Vanguard Group Inc | 2,878,451 | $450.9M | 0.01% | +28,707+1.0% | Added |
| Avoro Capital Advisors LLC | 2,628,822 | $411.8M | 5.83% | +6,600+0.3% | Added |
| State Street Corp | 1,278,975 | $200.4M | 0.01% | −173,836−12.0% | Reduced |
| Capital World Investors | 879,203 | $137.7M | 0.02% | +1200.0% | Added |
| Frazier Life Sciences Management, L.P. | 788,460 | $123.5M | 5.13% | −200,000−20.2% | Reduced |
| Redmile Group, LLC | 753,175 | $118.0M | 8.22% | −57,070−7.0% | Reduced |
| Geode Capital Management, LLC | 591,596 | $92.7M | 0.01% | −350.0% | Reduced |
| Dimensional Fund Advisors LP | 588,599 | $92.2M | 0.02% | −11,662−1.9% | Reduced |
| Hood River Capital Management LLC | 512,726 | $80.3M | 1.19% | +10,622+2.1% | Added |
| Price T Rowe Associates Inc | 509,459 | $79.8M | 0.01% | +71,200+16.2% | Added |
| Soleus Capital Management, L.P. | 358,379 | $56.1M | 4.25% | +141,400+65.2% | Added |
| Nuveen Asset Management, LLC | 304,115 | $47.6M | 0.01% | −7,740−2.5% | Reduced |
| Jennison Associates LLC | 303,521 | $47.5M | 0.03% | −106,536−26.0% | Reduced |
| Goldman Sachs Group Inc | 277,175 | $43.4M | 0.01% | −24,179−8.0% | Reduced |
| Invesco Ltd. | 275,195 | $43.1M | 0.01% | −90,356−24.7% | Reduced |
| Northern Trust Corp | 262,263 | $41.1M | 0.01% | +23,572+9.9% | Added |
| Morgan Stanley | 256,275 | $40.1M | 0.00% | −19,529−7.1% | Reduced |
| Charles Schwab Investment Management Inc | 243,170 | $38.1M | 0.01% | +2,954+1.2% | Added |
| Woodline Partners LP | 221,102 | $34.6M | 0.23% | +41,287+23.0% | Added |
| Norges Bank | 219,528 | $34.4M | 0.00% | −24,569−10.1% | Reduced |
| Lord, Abbett & Co. LLC | 215,628 | $33.8M | 0.11% | −68,531−24.1% | Reduced |
| UBS Asset Management Americas Inc | 210,202 | $32.9M | 0.01% | −14,743−6.6% | Reduced |
| Braidwell LP | 200,500 | $31.4M | 0.93% | +31,809+18.9% | Added |
| Franklin Resources Inc | 184,027 | $28.8M | 0.01% | −59,733−24.5% | Reduced |
| Baker Bros. Advisors LP | 169,934 | $26.6M | 0.28% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 169,346 | $26.5M | 0.00% | −2,307−1.3% | Reduced |
| TimesSquare Capital Management, LLC | 158,868 | $24.9M | 0.36% | +44,646+39.1% | Added |
| JPMorgan Chase & Co | 151,835 | $23.8M | 0.00% | +23,934+18.7% | Added |
| Segall Bryant & Hamill, LLC | 149,309 | $23.4M | 0.32% | −7,835−5.0% | Reduced |
| Principal Financial Group Inc | 123,453 | $19.3M | 0.01% | +3,727+3.1% | Added |
| Driehaus Capital Management LLC | 121,702 | $19.1M | 0.16% | −41,602−25.5% | Reduced |
| Ameriprise Financial Inc | 113,476 | $17.8M | 0.00% | +23,727+26.4% | Added |
| Pictet Asset Management Holding SA | 112,089 | $17.6M | 0.02% | −3,261−2.8% | Reduced |
| C WorldWide Group Holding A/S | 105,809 | $16.6M | 0.20% | −30,000−22.1% | Reduced |
| Raymond James Financial Inc | 102,061 | $16.0M | 0.01% | +102,061 | New |
| UBS Group AG | 100,131 | $15.7M | 0.00% | +63,802+175.6% | Added |
| Citigroup Inc | 99,633 | $15.6M | 0.02% | +64,549+184.0% | Added |
| Eventide Asset Management, LLC | 95,781 | $15.0M | 0.27% | 00.0% | Unchanged |
| S Squared Technology, LLC | 95,215 | $14.9M | 6.20% | +20,000+26.6% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 89,047 | $14.2M | 0.06% | −37,035−29.4% | Reduced |
| Handelsbanken Fonder AB | 85,300 | $13.4M | 0.05% | −9,400−9.9% | Reduced |
| Victory Capital Management Inc | 81,328 | $12.7M | 0.01% | −16,957−17.3% | Reduced |
| Decheng Capital LLC | 76,772 | $12.0M | 2.58% | +5,000+7.0% | Added |
| Bank of America Corp | 75,799 | $11.9M | 0.00% | −28,855−27.6% | Reduced |
| Voya Investment Management LLC | 74,701 | $11.7M | 0.01% | +4,123+5.8% | Added |
| Legal & General Group Plc | 69,425 | $10.9M | 0.00% | +3,170+4.8% | Added |
| Rhumbline Advisers | 69,136 | $10.8M | 0.01% | −1,173−1.7% | Reduced |
| Public Sector Pension Investment Board | 63,010 | $9.87M | 0.04% | +9,354+17.4% | Added |
| Standard Life Aberdeen plc | 57,033 | $8.93M | 0.02% | +13,979+32.5% | Added |
| Integral Health Asset Management, LLC | 55,000 | $8.62M | 0.76% | +55,000 | New |
| Janney Montgomery Scott LLC | 52,592 | $8.24M | 0.02% | +15,545+42.0% | Added |
| Barclays PLC | 52,429 | $8.21M | 0.00% | −4,111−7.3% | Reduced |
| Oberweis Asset Management Inc | 46,800 | $7.33M | 0.35% | 00.0% | Unchanged |
| Prudential Financial Inc | 41,193 | $6.82M | 0.01% | +3,254+8.6% | Added |
| TD Asset Management Inc | 43,480 | $6.81M | 0.01% | +10,000+29.9% | Added |
| CI Private Wealth, LLC | 43,009 | $6.74M | 0.01% | −4,678−9.8% | Reduced |
| Swiss National Bank | 42,400 | $6.64M | 0.00% | +3,300+8.4% | Added |
| Palisades Investment Partners, LLC | 40,479 | $6.34M | 2.68% | +3,436+9.3% | Added |
| Susquehanna International Group, LLP | 38,468 | $6.03M | 0.01% | +28,914+302.6% | Added |
| Mutual of America Capital Management LLC | 36,518 | $5.72M | 0.06% | −48−0.1% | Reduced |
| Jane Street Group, LLC | 35,855 | $5.62M | 0.01% | +17,674+97.2% | Added |
| Manufacturers Life Insurance Company, The | 35,206 | $5.52M | 0.00% | +3,981+12.7% | Added |
| GW&K Investment Management, LLC | 34,930 | $5.47M | 0.05% | −1,099−3.1% | Reduced |
| Alliancebernstein L.P. | 31,120 | $4.88M | 0.00% | +1,400+4.7% | Added |
| Allspring Global Investments Holdings, LLC | 29,777 | $4.66M | 0.01% | −81,928−73.3% | Reduced |
| Kennedy Capital Management, Inc. | 27,711 | $4.34M | 0.10% | +22,517+433.5% | Added |
| Rafferty Asset Management, LLC | 27,201 | $4.26M | 0.02% | −18,639−40.7% | Reduced |
| Great West Life Assurance Co | 26,754 | $4.19M | 0.01% | −22−0.1% | Reduced |
| Deutsche Bank AG | 25,361 | $3.97M | 0.00% | +9,750+62.5% | Added |
| Verition Fund Management LLC | 24,902 | $3.90M | 0.02% | +8,902+55.6% | Added |
| State of Wisconsin Investment Board | 24,502 | $3.84M | 0.01% | +1,434+6.2% | Added |
| Edgestream Partners, L.P. | 23,810 | $3.73M | 0.16% | −8,447−26.2% | Reduced |
| Rhenman & Partners Asset Management AB | 23,750 | $3.72M | 0.38% | +6,750+39.7% | Added |
| OrbiMed Advisors LLC | 23,500 | $3.68M | 0.08% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 23,382 | $3.66M | 0.00% | −2,481−9.6% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 23,197 | $3.63M | 0.01% | +23,197 | New |
| First Trust Advisors LP | 23,169 | $3.63M | 0.00% | −16,242−41.2% | Reduced |
| Caption Management, LLC | 22,339 | $3.50M | 0.14% | +22,339 | New |
| HRT Financial LP | 22,007 | $3.45M | 0.02% | +22,007 | New |
| SEI Investments Co | 21,164 | $3.32M | 0.00% | −13,085−38.2% | Reduced |
| California State Teachers Retirement System | 20,388 | $3.19M | 0.00% | +1,127+5.9% | Added |
| Thrivent Financial for Lutherans | 19,563 | $3.06M | 0.01% | −291−1.5% | Reduced |
| Millennium Management LLC | 18,956 | $2.97M | 0.00% | −28,667−60.2% | Reduced |
| Erste Asset Management GmbH | 18,200 | $2.90M | 0.04% | 00.0% | Unchanged |
| EFG Asset Management (North America) Corp. | 17,714 | $2.78M | 0.38% | +4,185+30.9% | Added |
| Wells Fargo & Company | 16,928 | $2.65M | 0.00% | +2,972+21.3% | Added |
| New York State Teachers Retirement System | 15,879 | $2.49M | 0.01% | 00.0% | Unchanged |
| Fiera Capital Corp | 15,673 | $2.46M | 0.01% | −527−3.3% | Reduced |
| DekaBank Deutsche Girozentrale | 15,503 | $2.44M | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 15,205 | $2.39M | 0.01% | −181−1.2% | Reduced |
| MetLife Investment Management | 14,997 | $2.35M | 0.01% | +680+4.7% | Added |
| State of Alaska, Department of Revenue | 14,423 | $2.26M | 0.03% | −50.0% | Reduced |
| Illinois Municipal Retirement Fund | 14,146 | $2.22M | 0.03% | +1,505+11.9% | Added |
| Hennion & Walsh Asset Management, Inc. | 13,678 | $2.14M | 0.10% | −232−1.7% | Reduced |
| Corebridge Financial, Inc. | 13,225 | $2.07M | 0.01% | −1,032−7.2% | Reduced |
| Federated Hermes, Inc. | 13,048 | $2.04M | 0.00% | +229+1.8% | Added |
| Schroder Investment Management Group | 12,607 | $2.01M | 0.00% | 00.0% | Unchanged |
| Louisiana State Employees Retirement System | 12,200 | $1.91M | 0.04% | 00.0% | Unchanged |