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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
264
−15 vs. Q3 2024
Shares held
27.8M
−399.3K (−1.4%) vs. Q3 2024
Total value
$4.35B
−$775.6M (−15.1%) vs. Q3 2024
New holders
37
95 more added
Sold out
52
97 more reduced

4 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 264 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ4 2024: $4.35B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2024.

Institutions holding KRYS in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
State of New Jersey Common Pension Fund D11,803$1.85M0.01%+1,910+19.3%Added
Wellington Management Group LLP11,704$1.83M0.00%−976−7.7%Reduced
Envestnet Asset Management Inc11,630$1.82M0.00%+121+1.1%Added
Redwood Investments, LLC11,343$1.78M0.48%−53−0.5%Reduced
State of Tennessee, Treasury Department11,299$1.77M0.01%−263−2.3%Reduced
Citadel Advisors LLC11,015$1.73M0.00%+10,919+11,374.0%Added
Renaissance Technologies LLC10,900$1.71M0.00%−3,500−24.3%Reduced
Intech Investment Management LLC10,839$1.70M0.02%+3,569+49.1%Added
Evolutionary Tree Capital Management, LLC10,700$1.68M1.71%+1,588+17.4%Added
Marshall Wace, LLP10,331$1.62M0.00%+10,331New
Janus Henderson Group PLC10,071$1.58M0.00%+1,400+16.1%Added
Los Angeles Capital Management LLC9,884$1.55M0.01%00.0%Unchanged
Yousif Capital Management, LLC9,777$1.53M0.02%−172−1.7%Reduced
ExodusPoint Capital Management, LP9,761$1.53M0.02%+9,761New
Squarepoint Ops LLC9,559$1.50M0.00%−6,147−39.1%Reduced
HealthInvest Partners AB9,202$1.47M0.70%00.0%Unchanged
AQR Capital Management LLC9,339$1.46M0.00%+989+11.8%Added
Privium Fund Management B.V.9,250$1.45M0.33%+2,900+45.7%Added
Zacks Investment Management9,078$1.42M0.01%−369−3.9%Reduced
Teachers Retirement System of the State of Kentucky9,010$1.41M0.01%00.0%Unchanged
Comerica Bank8,890$1.39M0.01%−207−2.3%Reduced
ProShare Advisors LLC8,848$1.39M0.00%+1,967+28.6%Added
Maryland State Retirement & Pension System8,523$1.34M0.03%−15−0.2%Reduced
CWM, LLC8,053$1.26M0.01%−5,793−41.8%Reduced
Jackson Creek Investment Advisors LLC8,052$1.26M0.38%−244−2.9%Reduced
BNP Paribas Arbitrage, SA7,789$1.22M0.00%−2,644−25.3%Reduced
Perigon Wealth Management, LLC8,289$1.20M0.03%+123+1.5%Added
Schonfeld Strategic Advisors LLC7,604$1.19M0.01%+1,153+17.9%Added
Blair William & Co7,443$1.17M0.00%+1,875+33.7%Added
Amalgamated Bank7,436$1.17M0.01%+20.0%Added
D. E. Shaw & Co., Inc.7,427$1.16M0.00%−1,919−20.5%Reduced
STRS Ohio7,300$1.14M0.00%+2,300+46.0%Added
Quantum Private Wealth, LLC7,205$1.13M0.36%00.0%Unchanged
Tower Research Capital LLC (TRC)6,999$1.10M0.02%+6,912+7,944.8%Added
Aquatic Capital Management LLC6,901$1.08M0.03%+6,901New
Ensign Peak Advisors, Inc6,569$1.03M0.00%00.0%Unchanged
Winton Group Ltd6,565$1.03M0.07%+1,274+24.1%Added
Teacher Retirement System of Texas6,383$1.00M0.00%+1,369+27.3%Added
Profund Advisors LLC6,321$990.2K0.04%−3,664−36.7%Reduced
Arizona State Retirement System6,242$977.9K0.01%+487+8.5%Added
China Universal Asset Management Co., Ltd.6,098$955.3K0.09%+572+10.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)6,054$948.4K0.00%+1,440+31.2%Added
Oregon Public Employees Retirement Fund5,975$936.0K0.02%−5−0.1%Reduced
State Board of Administration of Florida Retirement System5,807$909.7K0.00%−60−1.0%Reduced
Commonwealth of Pennsylvania Public School Empls Retrmt Sys5,403$846.4K0.01%−10.0%Reduced
Creative Planning5,397$845.5K0.00%−347−6.0%Reduced
Police & Firemen's Retirement System of New Jersey5,283$827.6K0.01%+5,283New
Martingale Asset Management L P5,136$804.6K0.02%+10.0%Added
Nicholas Investment Partners, LP5,086$796.8K0.07%−13,721−73.0%Reduced
Bellevue Group AG5,047$790.7K0.02%+268+5.6%Added
Commonwealth Equity Services, LLC4,866$762.0K0.00%+190+4.1%Added
Guggenheim Capital LLC4,862$761.7K0.01%+927+23.6%Added
Jain Global LLC4,800$752.0K0.02%+4,800New
HSBC Holdings PLC4,519$717.7K0.00%+2,988+195.2%Added
KLP Kapitalforvaltning AS4,300$673.6K0.00%+4,300New
CenterBook Partners LP4,283$671.0K0.04%+4,283New
Pathstone Holdings, LLC4,252$666.2K0.00%−795−15.8%Reduced
HighVista Strategies LLC4,217$660.6K0.25%+4,217New
Hussman Strategic Advisors, Inc.4,200$658.0K0.19%+4,200New
Allianz Asset Management GmbH4,102$642.6K0.00%+1,500+57.6%Added
Pier 88 Investment Partners LLC3,750$587.5K0.12%+220+6.2%Added
Cynosure Management, LLC3,630$568.7K0.08%−359−9.0%Reduced
Main Management ETF Advisors, LLC3,560$558.0K0.03%−320−8.2%Reduced
Entropy Technologies, LP3,500$548.3K0.06%+3,500New
Gsa Capital Partners LLP3,464$543.0K0.04%+3,464New
Summit Global Investments3,453$541.0K0.03%+3,453New
Mariner, LLC3,375$528.8K0.00%−247−6.8%Reduced
Credit Agricole S A3,336$522.6K0.00%00.0%Unchanged
Bank of Montreal3,325$520.9K0.00%+179+5.7%Added
Parallel Advisors, LLC3,237$507.1K0.01%00.0%Unchanged
Quest Partners LLC3,020$473.1K0.06%+1,622+116.0%Added
Vontobel Holding Ltd.2,984$467.5K0.00%−4,535−60.3%Reduced
LPL Financial LLC2,946$461.5K0.00%+1,799+156.8%Added
Confluence Wealth Services, Inc.2,920$452.8K0.03%00.0%Unchanged
Nebula Research & Development LLC2,670$418.3K0.05%−2,035−43.3%Reduced
Ameritas Investment Partners, Inc.2,595$406.5K0.01%+82+3.3%Added
Vident Advisory, LLC2,492$390.4K0.01%−83−3.2%Reduced
Public Employees Retirement Association of Colorado2,363$370.0K0.00%00.0%Unchanged
Sherbrooke Park Advisers LLC2,353$368.6K0.12%−26−1.1%Reduced
CIBC World Markets Corp2,321$363.6K0.00%+2,321New
Crossmark Global Holdings, Inc.2,307$362.0K0.01%+121+5.5%Added
Cetera Investment Advisers2,176$340.9K0.00%+31+1.4%Added
Fox Run Management, L.L.C.2,161$338.5K0.06%+2,161New
Ballentine Partners, LLC2,145$336.0K0.01%+56+2.7%Added
XTX Topco Ltd2,102$329.3K0.03%+2,102New
Graham Capital Management, L.P.2,082$326.2K0.01%−149−6.7%Reduced
Virtus ETF Advisers LLC2,016$315.8K0.13%+214+11.9%Added
Farallon Capital Management, L.L.C.2,000$313.3K0.00%00.0%Unchanged
E Fund Management Co., Ltd.1,934$303.0K0.02%−1,007−34.2%Reduced
Argent Trust Co1,899$297.5K0.01%00.0%Unchanged
Old Mission Capital LLC1,868$292.6K0.01%+1,868New
Xponance, Inc.1,785$279.6K0.00%+155+9.5%Added
The PNC Financial Services Group, Inc.1,680$263.2K0.00%+36+2.2%Added
Headlands Technologies LLC1,635$256.1K0.03%−5,199−76.1%Reduced
DnB Asset Management AS1,537$240.8K0.00%−759−33.1%Reduced
Mackenzie Financial Corp1,532$240.0K0.00%+46+3.1%Added
AlphaCentric Advisors LLC1,474$230.9K0.23%+1,474New
Sound View Wealth Advisors Group, LLC1,420$222.5K0.02%+220+18.3%Added
JustInvest LLC1,400$219.3K0.00%−138−9.0%Reduced
Pacer Advisors, Inc.1,400$219.3K0.00%+1,400New