Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 275
- −21 vs. Q1 2025
- Shares held
- 27.7M
- +56.6K (+0.2%) vs. Q1 2025
- Total value
- $3.80B
- −$1.17B (−23.6%) vs. Q1 2025
- New holders
- 42
- 101 more added
- Sold out
- 63
- 96 more reduced
3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 4,334,761 | $595.9M | 0.03% | +13,929+0.3% | Added |
| BlackRock, Inc. | 3,845,155 | $528.6M | 0.01% | −98,010−2.5% | Reduced |
| Vanguard Group Inc | 2,822,888 | $388.0M | 0.01% | −2,394−0.1% | Reduced |
| Avoro Capital Advisors LLC | 2,660,000 | $365.6M | 6.40% | −71,000−2.6% | Reduced |
| State Street Corp | 1,355,346 | $186.3M | 0.01% | +128,639+10.5% | Added |
| Capital World Investors | 942,249 | $129.5M | 0.02% | −12,219−1.3% | Reduced |
| Soleus Capital Management, L.P. | 922,958 | $126.9M | 8.76% | +481,200+108.9% | Added |
| Braidwell LP | 727,811 | $100.0M | 3.42% | +327,067+81.6% | Added |
| Frazier Life Sciences Management, L.P. | 688,460 | $94.6M | 3.78% | 00.0% | Unchanged |
| Redmile Group, LLC | 663,471 | $91.2M | 9.71% | −74,204−10.1% | Reduced |
| Geode Capital Management, LLC | 619,547 | $85.2M | 0.01% | +7,194+1.2% | Added |
| Hood River Capital Management LLC | 533,023 | $73.3M | 1.02% | +8,379+1.6% | Added |
| Goldman Sachs Group Inc | 530,361 | $72.9M | 0.01% | +296,721+127.0% | Added |
| Dimensional Fund Advisors LP | 505,889 | $69.5M | 0.02% | −28,030−5.2% | Reduced |
| Norges Bank | 282,706 | $38.9M | 0.00% | +9,497+3.5% | Added |
| Price T Rowe Associates Inc | 261,383 | $35.9M | 0.00% | −149,478−36.4% | Reduced |
| Northern Trust Corp | 251,408 | $34.6M | 0.00% | −8,587−3.3% | Reduced |
| Charles Schwab Investment Management Inc | 246,180 | $33.8M | 0.01% | −4,334−1.7% | Reduced |
| Morgan Stanley | 234,421 | $32.2M | 0.00% | −63,784−21.4% | Reduced |
| UBS Asset Management Americas Inc | 234,320 | $32.2M | 0.01% | −341,186−59.3% | Reduced |
| First Trust Advisors LP | 222,370 | $30.6M | 0.02% | +189,245+571.3% | Added |
| Nuveen, LLC | 188,019 | $25.8M | 0.01% | −46,161−19.7% | Reduced |
| Bank of New York Mellon Corp | 160,517 | $22.1M | 0.00% | −8,662−5.1% | Reduced |
| Woodline Partners LP | 150,616 | $20.7M | 0.11% | −71,427−32.2% | Reduced |
| Segall Bryant & Hamill, LLC | 148,614 | $20.4M | 0.29% | +3,277+2.3% | Added |
| Readystate Asset Management LP | 147,980 | $20.3M | 0.84% | +147,980 | New |
| Principal Financial Group Inc | 140,883 | $19.4M | 0.01% | +14,546+11.5% | Added |
| Pictet Asset Management Holding SA | 130,537 | $17.9M | 0.02% | +65,275+100.0% | Added |
| Bank of America Corp | 121,812 | $16.7M | 0.00% | +29,251+31.6% | Added |
| TimesSquare Capital Management, LLC | 114,204 | $15.7M | 0.23% | −27,979−19.7% | Reduced |
| Marshall Wace, LLP | 112,382 | $15.4M | 0.02% | +95,158+552.5% | Added |
| S Squared Technology, LLC | 109,215 | $15.0M | 6.33% | +12,000+12.3% | Added |
| Standard Life Aberdeen plc | 108,518 | $14.9M | 0.03% | +71,217+190.9% | Added |
| Logos Global Management LP | 100,000 | $13.7M | 1.84% | +100,000 | New |
| UBS Group AG | 97,240 | $13.4M | 0.00% | +16,121+19.9% | Added |
| Barclays PLC | 92,871 | $12.8M | 0.01% | +47,874+106.4% | Added |
| JPMorgan Chase & Co | 91,153 | $12.5M | 0.00% | −9,621−9.5% | Reduced |
| William Blair Investment Management, LLC | 91,099 | $12.5M | 0.03% | +91,099 | New |
| Renaissance Technologies LLC | 89,800 | $12.3M | 0.02% | +78,600+701.8% | Added |
| Public Sector Pension Investment Board | 86,688 | $11.9M | 0.05% | +6,424+8.0% | Added |
| C WorldWide Group Holding A/S | 85,809 | $11.8M | 0.16% | 00.0% | Unchanged |
| Victory Capital Management Inc | 80,123 | $11.0M | 0.01% | +7,308+10.0% | Added |
| Invesco Ltd. | 70,888 | $9.74M | 0.00% | −183,598−72.1% | Reduced |
| Rhumbline Advisers | 70,753 | $9.73M | 0.01% | +2,026+2.9% | Added |
| Raymond James Financial Inc | 68,735 | $9.45M | 0.00% | +2,774+4.2% | Added |
| Legal & General Group Plc | 68,393 | $9.40M | 0.00% | +1,884+2.8% | Added |
| Handelsbanken Fonder AB | 66,800 | $9.18M | 0.03% | −7,500−10.1% | Reduced |
| Decheng Capital LLC | 66,000 | $9.07M | 2.29% | +1,000+1.5% | Added |
| Voya Investment Management LLC | 63,993 | $8.80M | 0.01% | −608−0.9% | Reduced |
| Ameriprise Financial Inc | 62,835 | $8.64M | 0.00% | +2,327+3.8% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 59,978 | $8.24M | 0.04% | 00.0% | Unchanged |
| Alyeska Investment Group, L.P. | 53,934 | $7.41M | 0.03% | +53,934 | New |
| Citigroup Inc | 52,533 | $7.22M | 0.01% | −20,992−28.6% | Reduced |
| Federated Hermes, Inc. | 42,743 | $5.88M | 0.01% | +29,962+234.4% | Added |
| Swiss National Bank | 41,400 | $5.69M | 0.00% | −400−1.0% | Reduced |
| CI Private Wealth, LLC | 40,538 | $5.57M | 0.01% | −1,589−3.8% | Reduced |
| Palisades Investment Partners, LLC | 40,203 | $5.53M | 2.42% | −493−1.2% | Reduced |
| Mutual of America Capital Management LLC | 38,357 | $5.27M | 0.06% | +1,926+5.3% | Added |
| Kennedy Capital Management, Inc. | 38,146 | $5.24M | 0.13% | −3,372−8.1% | Reduced |
| State of Wisconsin Investment Board | 36,089 | $4.96M | 0.01% | +11,906+49.2% | Added |
| Rafferty Asset Management, LLC | 34,665 | $4.77M | 0.02% | +10,504+43.5% | Added |
| Citadel Advisors LLC | 34,560 | $4.75M | 0.00% | +34,464+35,900.0% | Added |
| Prudential Financial Inc | 26,151 | $4.42M | 0.01% | −1,160−4.2% | Reduced |
| Alliancebernstein L.P. | 31,120 | $4.28M | 0.00% | 00.0% | Unchanged |
| Man Group plc | 30,481 | $4.19M | 0.01% | +30,481 | New |
| Susquehanna International Group, LLP | 30,252 | $4.16M | 0.01% | −3,577−10.6% | Reduced |
| GW&K Investment Management, LLC | 30,175 | $4.15M | 0.04% | −3,925−11.5% | Reduced |
| Los Angeles Capital Management LLC | 26,638 | $3.66M | 0.01% | +1,709+6.9% | Added |
| Verition Fund Management LLC | 26,514 | $3.64M | 0.02% | +7,889+42.4% | Added |
| Manufacturers Life Insurance Company, The | 24,680 | $3.39M | 0.00% | −7,686−23.7% | Reduced |
| New York State Common Retirement Fund | 23,382 | $3.21M | 0.00% | 00.0% | Unchanged |
| EFG Asset Management (North America) Corp. | 22,878 | $3.14M | 0.44% | +5,507+31.7% | Added |
| Biondo Investment Advisors, LLC | 21,240 | $2.92M | 0.38% | +21,240 | New |
| Great West Life Assurance Co | 20,847 | $2.86M | 0.00% | −3,762−15.3% | Reduced |
| Synovus Financial Corp | 20,643 | $2.84M | 0.03% | +20,643 | New |
| HealthInvest Partners AB | 20,158 | $2.77M | 1.19% | −3,333−14.2% | Reduced |
| California State Teachers Retirement System | 20,126 | $2.77M | 0.00% | 00.0% | Unchanged |
| TD Asset Management Inc | 20,080 | $2.76M | 0.00% | −20,188−50.1% | Reduced |
| Edgestream Partners, L.P. | 19,678 | $2.70M | 0.08% | +19,678 | New |
| SEI Investments Co | 19,300 | $2.65M | 0.00% | +609+3.3% | Added |
| Deutsche Bank AG | 19,135 | $2.63M | 0.00% | −2,602−12.0% | Reduced |
| Thrivent Financial for Lutherans | 18,700 | $2.57M | 0.01% | +110+0.6% | Added |
| Franklin Resources Inc | 18,425 | $2.53M | 0.00% | −588−3.1% | Reduced |
| Erste Asset Management GmbH | 18,200 | $2.53M | 0.02% | 00.0% | Unchanged |
| Alps Advisors Inc | 17,462 | $2.40M | 0.01% | +15,542+809.5% | Added |
| Wells Fargo & Company | 16,547 | $2.27M | 0.00% | −588−3.4% | Reduced |
| New York State Teachers Retirement System | 15,650 | $2.15M | 0.00% | −329−2.1% | Reduced |
| DekaBank Deutsche Girozentrale | 15,503 | $2.15M | 0.00% | 00.0% | Unchanged |
| Fiera Capital Corp | 15,511 | $2.13M | 0.01% | −134−0.9% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 15,283 | $2.10M | 0.00% | −610−3.8% | Reduced |
| State of Alaska, Department of Revenue | 15,130 | $2.08M | 0.02% | +1,106+7.9% | Added |
| Envestnet Asset Management Inc | 15,116 | $2.08M | 0.00% | +2,717+21.9% | Added |
| State of New Jersey Common Pension Fund D | 15,033 | $2.07M | 0.01% | +4,682+45.2% | Added |
| MetLife Investment Management | 14,746 | $2.03M | 0.01% | +222+1.5% | Added |
| Fieldview Capital Management, LLC | 14,546 | $2.00M | 0.30% | −1,796−11.0% | Reduced |
| Rhenman & Partners Asset Management AB | 12,750 | $1.75M | 0.22% | −5,000−28.2% | Reduced |
| SG Americas Securities, LLC | 12,607 | $1.73M | 0.01% | +11,295+860.9% | Added |
| Millennium Management LLC | 12,562 | $1.73M | 0.00% | −47,826−79.2% | Reduced |
| Illinois Municipal Retirement Fund | 12,311 | $1.69M | 0.02% | −451−3.5% | Reduced |
| Evolutionary Tree Capital Management, LLC | 12,296 | $1.69M | 1.79% | −1,047−7.8% | Reduced |