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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
275
−21 vs. Q1 2025
Shares held
27.7M
+56.6K (+0.2%) vs. Q1 2025
Total value
$3.80B
−$1.17B (−23.6%) vs. Q1 2025
New holders
42
101 more added
Sold out
63
96 more reduced

3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 275 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ2 2025: $3.80B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2025.

Institutions holding KRYS in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Avion Wealth4$00.00%+4New
Essential Partners LLC1$1370.00%+1New
Abound Wealth Management1$1380.00%00.0%Unchanged
Tradewinds Capital Management, LLC1$1380.00%+1New
JFS Wealth Advisors, LLC2$2750.00%00.0%Unchanged
Larson Financial Group LLC2$2750.00%+2New
Parkworth Wealth Management, Inc.2$2750.00%+2New
Hughes Financial Services, LLC4$5440.00%+4New
Fortitude Family Office, LLC4$5500.00%+4New
Rakuten Securities, Inc.5$6870.00%00.0%Unchanged
Glen Eagle Advisors, LLC5$6870.00%00.0%Unchanged
Atlantic Trust, LLC5$6880.00%+5New
Ronald Blue Trust, Inc.6$8250.00%−3−33.3%Reduced
SRS Capital Advisors, Inc.6$8250.00%+6New
Wolff Wiese Magana LLC8$1.10K0.00%00.0%Unchanged
Geneos Wealth Management Inc.8$1.10K0.00%00.0%Unchanged
IFP Advisors, Inc10$1.37K0.00%+10New
Sound Income Strategies, LLC10$1.38K0.00%00.0%Unchanged
Principal Securities, Inc.10$1.38K0.00%+3+42.9%Added
Global Retirement Partners, LLC11$1.51K0.00%+11New
Kestra Investment Management, LLC10$1.59K0.00%+5+100.0%Added
Farmers & Merchants Investments Inc15$2.06K0.00%00.0%Unchanged
Parkside Financial Bank & Trust15$2.06K0.00%−6−28.6%Reduced
Bell Investment Advisors, Inc19$2.61K0.00%00.0%Unchanged
Trust Co of Vermont20$2.75K0.00%00.0%Unchanged
Farther Finance Advisors, LLC24$3.30K0.00%+1+4.3%Added
Clearstead Advisors, LLC24$3.30K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC31$4.26K0.00%−24−43.6%Reduced
Jones Financial Companies LLLP32$4.44K0.00%+32New
GWM Advisors LLC34$4.72K0.00%00.0%Unchanged
Twin Peaks Wealth Advisors, LLC35$5.03K0.00%+35New
Rothschild Investment LLC39$5.36K0.00%−7−15.2%Reduced
Umb Bank N A43$5.91K0.00%−30−41.1%Reduced
Bare Financial Services, Inc43$5.91K0.00%+32+290.9%Added
Allworth Financial LP44$6.05K0.00%+18+69.2%Added
Federation des caisses Desjardins du Quebec50$6.87K0.00%00.0%Unchanged
Private Wealth Management Group, LLC55$7.56K0.00%+50+1,000.0%Added
Massmutual Trust Co FSB60$8.25K0.00%+8+15.4%Added
Sterling Capital Management LLC60$8.25K0.00%+34+130.8%Added
Rise Advisors, LLC66$9.07K0.00%00.0%Unchanged
Versant Capital Management, Inc69$9.48K0.00%+32+86.5%Added
SBI Securities Co., Ltd.70$9.62K0.00%−1−1.4%Reduced
Bessemer Group Inc72$10.0K0.00%+3+4.3%Added
Signaturefd, LLC79$10.9K0.00%−51−39.2%Reduced
Fifth Third Bancorp90$12.4K0.00%−81−47.4%Reduced
Reyes Financial Architecture, Inc.100$13.7K0.01%+100New
Daiwa Securities Group Inc.104$14.0K0.00%+9+9.5%Added
Key Financial Inc151$20.8K0.00%00.0%Unchanged
Lazard Asset Management LLC155$21.0K0.00%−249−61.6%Reduced
MAI Capital Management158$21.7K0.00%+24+17.9%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.174$24.0K0.00%+174New
Hantz Financial Services, Inc.181$25.0K0.00%+179+8,950.0%Added
Danske Bank A/S200$27.5K0.00%+200New
Skopos Labs, Inc.202$27.8K0.00%+61+43.3%Added
Smartleaf Asset Management LLC210$29.2K0.00%−105−33.3%Reduced
Bryn Mawr Trust Co220$30.2K0.00%−5−2.2%Reduced
First Horizon Advisors, Inc.244$33.5K0.00%+166+212.8%Added
Caldwell Trust Co250$34.4K0.00%00.0%Unchanged
Huntington National Bank256$35.2K0.00%+43+20.2%Added
GAMMA Investing LLC285$39.2K0.00%−388−57.7%Reduced
Advisor Group Holdings, Inc.393$54.3K0.00%+115+41.4%Added
Pacer Advisors, Inc.455$62.5K0.00%−253−35.7%Reduced
US Bancorp504$69.3K0.00%−135−21.1%Reduced
Headlands Technologies LLC527$72.4K0.01%−483−47.8%Reduced
Quest Partners LLC579$79.6K0.01%−1,084−65.2%Reduced
Asset Management One Co.,Ltd.617$84.8K0.00%+617New
KBC Group NV685$94.0K0.00%−254−27.1%Reduced
GF Fund Management Co. Ltd.736$101.2K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC886$121.8K0.00%−34−3.7%Reduced
Avanza Fonder AB941$129.3K0.00%−319−25.3%Reduced
Canada Pension Plan Investment Board1,000$137.5K0.00%−300−23.1%Reduced
Mirae Asset Global Investments Co., Ltd.1,116$153.4K0.00%+152+15.8%Added
Financiere des Professionnels - Fonds d,investissement inc.1,182$162.5K0.01%+1,182New
Bellevue Group AG1,250$171.8K0.00%−1,400−52.8%Reduced
Mount Yale Investment Advisors, LLC1,251$172.0K0.01%+12+1.0%Added
Covestor Ltd1,373$189.0K0.11%−124−8.3%Reduced
The PNC Financial Services Group, Inc.1,422$195.5K0.00%−719−33.6%Reduced
Hilltop Holdings Inc.1,468$201.8K0.01%+272+22.7%Added
Algert Global LLC1,500$206.2K0.00%+1,500New
CWM, LLC1,583$218.0K0.00%+107+7.2%Added
Mackenzie Financial Corp1,597$219.5K0.00%+65+4.2%Added
JustInvest LLC1,695$233.0K0.00%−251−12.9%Reduced
DnB Asset Management AS1,731$237.9K0.00%−48−2.7%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,795$246.7K0.00%+303+20.3%Added
Royal Bank of Canada1,811$249.0K0.00%+183+11.2%Added
Parallel Advisors, LLC1,863$256.1K0.01%+132+7.6%Added
OmniStar Financial Group, Inc.1,878$258.1K0.19%−148−7.3%Reduced
Freestone Grove Partners LP1,895$260.5K0.00%+1,895New
Xponance, Inc.1,929$265.2K0.00%+56+3.0%Added
Aigen Investment Management, LP1,944$267.2K0.04%+1,944New
Sound View Wealth Advisors Group, LLC1,947$267.6K0.02%+432+28.5%Added
Vident Advisory, LLC1,982$272.4K0.00%−805−28.9%Reduced
Campbell & CO Investment Adviser LLC1,991$273.7K0.02%+1,991New
Farallon Capital Management, L.L.C.2,000$274.9K0.00%00.0%Unchanged
Allspring Global Investments Holdings, LLC2,068$287.5K0.00%−3,112−60.1%Reduced
Ballentine Partners, LLC2,115$290.7K0.00%−21−1.0%Reduced
Capstone Investment Advisors, LLC2,196$301.9K0.00%+2,196New
Janney Montgomery Scott LLC2,340$322.0K0.00%−43,595−94.9%Reduced
Nebula Research & Development LLC2,355$323.7K0.03%−3,865−62.1%Reduced
Public Employees Retirement Association of Colorado2,363$325.0K0.00%00.0%Unchanged