Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 368
- +41 vs. Q4 2025
- Shares held
- 28.4M
- +3.02M (+11.9%) vs. Q4 2025
- Total value
- $7.32B
- +$1.08B (+17.2%) vs. Q4 2025
- New holders
- 76
- 138 more added
- Sold out
- 35
- 105 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 4,373,987 | $1.13B | 0.06% | +24,359+0.6% | Added |
| BlackRock, Inc. | 3,940,456 | $1.02B | 0.02% | +2,639+0.1% | Added |
| Avoro Capital Advisors LLC | 2,888,888 | $746.3M | 7.35% | 00.0% | Unchanged |
| Vanguard Portfolio Management LLC | 1,456,727 | $376.3M | 0.02% | +1,456,727 | New |
| State Street Corp | 1,314,434 | $339.5M | 0.01% | −27,869−2.1% | Reduced |
| Vanguard Capital Management LLC | 1,165,324 | $301.0M | 0.01% | +1,165,324 | New |
| Soleus Capital Management, L.P. | 1,153,087 | $297.9M | 12.06% | +212,028+22.5% | Added |
| Capital World Investors | 824,720 | $213.0M | 0.03% | +15,220+1.9% | Added |
| Redmile Group, LLC | 673,505 | $174.0M | 11.52% | −4,200−0.6% | Reduced |
| Geode Capital Management, LLC | 643,975 | $166.4M | 0.01% | +32,097+5.2% | Added |
| Hood River Capital Management LLC | 619,586 | $160.1M | 1.61% | +6,284+1.0% | Added |
| Price T Rowe Associates Inc | 485,074 | $125.3M | 0.01% | −44,881−8.5% | Reduced |
| Bellevue Group AG | 481,785 | $124.5M | 2.96% | +71,462+17.4% | Added |
| Frazier Life Sciences Management, L.P. | 481,307 | $124.3M | 3.20% | −7,153−1.5% | Reduced |
| Dimensional Fund Advisors LP | 468,990 | $121.1M | 0.03% | −23,978−4.9% | Reduced |
| William Blair Investment Management, LLC | 407,178 | $105.2M | 0.35% | +30,838+8.2% | Added |
| First Trust Advisors LP | 350,521 | $90.5M | 0.06% | +105,245+42.9% | Added |
| Janus Henderson Group PLC | 266,659 | $68.9M | 0.03% | +47,219+21.5% | Added |
| Bank of America Corp | 260,647 | $67.3M | 0.00% | +69,840+36.6% | Added |
| Northern Trust Corp | 252,463 | $65.2M | 0.01% | +5,020+2.0% | Added |
| Invesco Ltd. | 251,373 | $64.9M | 0.01% | +191,365+318.9% | Added |
| Charles Schwab Investment Management Inc | 241,986 | $62.5M | 0.01% | −788−0.3% | Reduced |
| Goldman Sachs Group Inc | 214,949 | $55.5M | 0.01% | −78,576−26.8% | Reduced |
| Morgan Stanley | 209,082 | $54.0M | 0.00% | −12,399−5.6% | Reduced |
| Braidwell LP | 182,425 | $47.1M | 1.57% | −19,676−9.7% | Reduced |
| Franklin Resources Inc | 179,265 | $46.3M | 0.01% | +53,590+42.6% | Added |
| Vanguard Fiduciary Trust Co | 179,161 | $46.3M | 0.01% | +179,161 | New |
| Principal Financial Group Inc | 162,070 | $41.9M | 0.02% | −3,004−1.8% | Reduced |
| Raymond James Financial Inc | 156,064 | $39.5M | 0.01% | +79,526+103.9% | Added |
| Woodline Partners LP | 150,616 | $38.9M | 0.15% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 149,307 | $38.6M | 0.01% | −2,006−1.3% | Reduced |
| UBS Group AG | 143,525 | $37.1M | 0.01% | −16,070−10.1% | Reduced |
| Nuveen, LLC | 143,368 | $37.0M | 0.01% | −45,726−24.2% | Reduced |
| TimesSquare Capital Management, LLC | 112,342 | $29.0M | 0.49% | +14,942+15.3% | Added |
| Pictet Asset Management Holding SA | 110,665 | $28.6M | 0.03% | −45,903−29.3% | Reduced |
| Voya Investment Management LLC | 108,397 | $28.0M | 0.03% | +5,136+5.0% | Added |
| JPMorgan Chase & Co | 99,105 | $24.5M | 0.00% | −35,519−26.4% | Reduced |
| BNP Paribas Arbitrage, SA | 93,031 | $24.0M | 0.02% | +39,120+72.6% | Added |
| Public Sector Pension Investment Board | 92,286 | $23.8M | 0.07% | +2,924+3.3% | Added |
| Handelsbanken Fonder AB | 91,400 | $23.6M | 0.08% | −14,400−13.6% | Reduced |
| S Squared Technology, LLC | 86,215 | $22.3M | 8.43% | −10,000−10.4% | Reduced |
| Segall Bryant & Hamill, LLC | 79,497 | $20.5M | 0.29% | −3,749−4.5% | Reduced |
| Biondo Investment Advisors, LLC | 72,045 | $18.6M | 2.39% | +3,915+5.7% | Added |
| OrbiMed Advisors LLC | 69,100 | $17.8M | 0.41% | −50,700−42.3% | Reduced |
| Marshall Wace, LLP | 68,343 | $17.7M | 0.02% | −115,411−62.8% | Reduced |
| Rhumbline Advisers | 68,099 | $17.6M | 0.02% | +1,663+2.5% | Added |
| C WorldWide Group Holding A/S | 67,809 | $17.5M | 0.38% | −18,000−21.0% | Reduced |
| ACT Capital Management, LLC | 60,477 | $15.6M | 12.28% | −230.0% | Reduced |
| Legal & General Group Plc | 59,050 | $15.3M | 0.00% | −4,311−6.8% | Reduced |
| Ameriprise Financial Inc | 49,837 | $12.9M | 0.00% | −2,508−4.8% | Reduced |
| SEI Investments Co | 46,570 | $12.0M | 0.01% | +14,260+44.1% | Added |
| Bridgewater Associates, LP | 46,367 | $12.0M | 0.05% | +36,352+363.0% | Added |
| SEB Asset Management AB | 46,343 | $12.0M | 0.05% | +46,343 | New |
| Palisades Investment Partners, LLC | 45,405 | $11.7M | 4.60% | +2,640+6.2% | Added |
| TD Asset Management Inc | 43,318 | $11.2M | 0.01% | −10,824−20.0% | Reduced |
| Swiss National Bank | 43,000 | $11.1M | 0.01% | +100+0.2% | Added |
| 1832 Asset Management L.P. | 42,600 | $11.0M | 0.01% | +25,000+142.0% | Added |
| Victory Capital Management Inc | 40,715 | $10.5M | 0.01% | +14,254+53.9% | Added |
| Gilder Gagnon Howe & Co LLC | 40,128 | $10.4M | 0.12% | +40,128 | New |
| UBS Asset Management Americas Inc | 36,937 | $9.54M | 0.00% | +3,320+9.9% | Added |
| Manufacturers Life Insurance Company, The | 36,069 | $9.32M | 0.01% | −4,560−11.2% | Reduced |
| Mutual of America Capital Management LLC | 35,859 | $9.26M | 0.11% | −1,410−3.8% | Reduced |
| Federated Hermes, Inc. | 35,495 | $9.17M | 0.01% | +954+2.8% | Added |
| Neuberger Berman Group LLC | 33,084 | $8.55M | 0.01% | +32,051+3,102.7% | Added |
| Castleark Management LLC | 31,630 | $8.17M | 0.27% | +2,370+8.1% | Added |
| New York State Common Retirement Fund | 31,342 | $8.10M | 0.01% | 00.0% | Unchanged |
| Citigroup Inc | 31,172 | $8.05M | 0.01% | +1,229+4.1% | Added |
| Alliancebernstein L.P. | 31,929 | $7.87M | 0.00% | +400+1.3% | Added |
| Standard Life Aberdeen plc | 30,155 | $7.79M | 0.01% | −9,205−23.4% | Reduced |
| Prudential Financial Inc | 29,638 | $7.66M | 0.01% | +2,623+9.7% | Added |
| Fisher Asset Management, LLC | 27,784 | $7.18M | 0.00% | +23,998+633.9% | Added |
| HealthInvest Partners AB | 37,579 | $6.79M | 2.19% | +3,726+11.0% | Added |
| Russell Investments Group, Ltd. | 26,210 | $6.77M | 0.01% | −2,744−9.5% | Reduced |
| California State Teachers Retirement System | 26,186 | $6.76M | 0.01% | +5,603+27.2% | Added |
| Deutsche Bank AG | 24,831 | $6.41M | 0.00% | +2,381+10.6% | Added |
| Granite Investment Partners, LLC | 24,284 | $6.27M | 0.39% | −1,476−5.7% | Reduced |
| Fiera Capital Corp | 24,146 | $6.24M | 0.02% | +5,289+28.0% | Added |
| Elmind Capital, LP | 22,000 | $5.68M | 1.61% | 00.0% | Unchanged |
| Great West Life Assurance Co | 21,413 | $5.53M | 0.01% | −674−3.1% | Reduced |
| State of Wisconsin Investment Board | 20,691 | $5.34M | 0.01% | +6,225+43.0% | Added |
| Vanguard Asset Management, Ltd | 20,606 | $5.32M | 0.00% | +20,606 | New |
| Bessemer Group Inc | 20,285 | $5.24M | 0.01% | +25+0.1% | Added |
| Pinnacle Financial Partners, Inc. | 20,180 | $5.21M | 0.04% | +3,197+18.8% | Added |
| EFG International AG | 20,049 | $5.18M | 0.11% | −3,520−14.9% | Reduced |
| ADAR1 Capital Management, LLC | 20,014 | $5.17M | 0.31% | 00.0% | Unchanged |
| Polygon Management Ltd. | 19,668 | $5.08M | 1.00% | +7,854+66.5% | Added |
| GW&K Investment Management, LLC | 19,245 | $4.97M | 0.04% | −336−1.7% | Reduced |
| Lisanti Capital Growth, LLC | 18,515 | $4.78M | 1.21% | +18,515 | New |
| Zacks Investment Management | 17,919 | $4.63M | 0.04% | +17,919 | New |
| Campbell & CO Investment Adviser LLC | 17,795 | $4.60M | 0.26% | +17,795 | New |
| Rafferty Asset Management, LLC | 17,687 | $4.57M | 0.02% | −6,581−27.1% | Reduced |
| State of Alaska, Department of Revenue | 17,484 | $4.51M | 0.05% | −418−2.3% | Reduced |
| Thrivent Financial for Lutherans | 17,226 | $4.45M | 0.01% | −508−2.9% | Reduced |
| Rhenman & Partners Asset Management AB | 16,675 | $4.31M | 0.53% | −8,325−33.3% | Reduced |
| EAM Investors, LLC | 16,483 | $4.26M | 0.49% | −8,184−33.2% | Reduced |
| Creative Planning | 15,937 | $4.12M | 0.00% | +2,056+14.8% | Added |
| State Board of Administration of Florida Retirement System | 15,756 | $4.07M | 0.01% | 00.0% | Unchanged |
| New York State Teachers Retirement System | 15,637 | $4.04M | 0.01% | −13−0.1% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 15,121 | $3.89M | 0.01% | +2,167+16.7% | Added |
| Cim, LLC | 14,990 | $3.87M | 0.56% | +14,990 | New |