Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 368
- +41 vs. Q4 2025
- Shares held
- 28.4M
- +3.02M (+11.9%) vs. Q4 2025
- Total value
- $7.32B
- +$1.08B (+17.2%) vs. Q4 2025
- New holders
- 76
- 138 more added
- Sold out
- 35
- 105 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wells Fargo & Company | 14,988 | $3.87M | 0.00% | −16,584−52.5% | Reduced |
| Tudor Investment Corp Et Al | 14,476 | $3.74M | 0.02% | +13,101+952.8% | Added |
| Illinois Municipal Retirement Fund | 14,151 | $3.66M | 0.05% | +1,452+11.4% | Added |
| AQR Capital Management LLC | 14,114 | $3.65M | 0.00% | −43−0.3% | Reduced |
| MetLife Investment Management | 13,542 | $3.50M | 0.02% | −302−2.2% | Reduced |
| Intech Investment Management LLC | 13,520 | $3.49M | 0.03% | +3,769+38.7% | Added |
| Credit Agricole S A | 12,976 | $3.35M | 0.01% | 00.0% | Unchanged |
| Evolutionary Tree Capital Management, LLC | 12,314 | $3.18M | 5.98% | −4,497−26.8% | Reduced |
| Natixis Advisors, L.P. | 12,125 | $3.13M | 0.00% | +443+3.8% | Added |
| Bridge City Capital, LLC | 12,045 | $3.11M | 0.86% | −90−0.7% | Reduced |
| Torray LLC | 12,032 | $3.11M | 0.46% | +47+0.4% | Added |
| Envestnet Asset Management Inc | 11,983 | $3.10M | 0.00% | +1,406+13.3% | Added |
| Commonwealth Equity Services, LLC | 11,591 | $2.99M | 0.00% | +1,704+17.2% | Added |
| Louisiana State Employees Retirement System | 11,400 | $2.94M | 0.05% | −400−3.4% | Reduced |
| Vanguard Global Advisers, LLC | 11,276 | $2.91M | 0.00% | +11,276 | New |
| Privium Fund Management B.V. | 11,170 | $2.89M | 0.60% | −1,000−8.2% | Reduced |
| Atika Capital Management LLC | 10,625 | $2.74M | 0.43% | +10,625 | New |
| State of Tennessee, Treasury Department | 10,254 | $2.65M | 0.01% | +61+0.6% | Added |
| Wellington Management Group LLP | 10,227 | $2.64M | 0.00% | −424−4.0% | Reduced |
| Nomura Asset Management International Inc. | 10,218 | $2.64M | 0.00% | +627+6.5% | Added |
| Renaissance Technologies LLC | 9,600 | $2.48M | 0.00% | +6,300+190.9% | Added |
| Virginia Retirement Systems Et Al | 9,500 | $2.45M | 0.02% | +500+5.6% | Added |
| Brown Capital Management LLC | 9,247 | $2.39M | 0.34% | +9,247 | New |
| Susquehanna International Group, LLP | 9,042 | $2.34M | 0.00% | +7,175+384.3% | Added |
| Profund Advisors LLC | 8,790 | $2.27M | 0.08% | −1,097−11.1% | Reduced |
| Clough Capital Partners L P | 8,502 | $2.20M | 0.21% | +696+8.9% | Added |
| Erste Asset Management GmbH | 8,700 | $2.15M | 0.02% | +3,000+52.6% | Added |
| Aquatic Capital Management LLC | 8,257 | $2.13M | 0.06% | +8,257 | New |
| Tealwood Asset Management Inc | 7,664 | $1.98M | 0.90% | −49−0.6% | Reduced |
| XTX Topco Ltd | 7,479 | $1.93M | 0.03% | +7,479 | New |
| State of New Jersey Common Pension Fund D | 7,433 | $1.92M | 0.01% | +24+0.3% | Added |
| Amalgamated Bank | 7,379 | $1.91M | 0.01% | −107−1.4% | Reduced |
| Decheng Capital LLC | 7,300 | $1.89M | 0.29% | −10,000−57.8% | Reduced |
| Martingale Asset Management L P | 7,208 | $1.86M | 0.05% | +2,702+60.0% | Added |
| Quantum Private Wealth, LLC | 7,181 | $1.85M | 0.57% | 00.0% | Unchanged |
| Yousif Capital Management, LLC | 7,131 | $1.84M | 0.02% | −36−0.5% | Reduced |
| Legato Capital Management LLC | 6,973 | $1.80M | 0.16% | +5,060+264.5% | Added |
| Police & Firemen's Retirement System of New Jersey | 6,747 | $1.74M | 0.01% | 00.0% | Unchanged |
| Teachers Retirement System of the State of Kentucky | 6,458 | $1.67M | 0.01% | 00.0% | Unchanged |
| STRS Ohio | 6,400 | $1.65M | 0.01% | −100−1.5% | Reduced |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 6,382 | $1.65M | 0.01% | −7−0.1% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 6,229 | $1.61M | 0.00% | +1,143+22.5% | Added |
| Cetera Investment Advisers | 6,206 | $1.60M | 0.00% | +1,590+34.4% | Added |
| Sanctuary Advisors, LLC | 6,030 | $1.56M | 0.01% | +6,030 | New |
| Arizona State Retirement System | 5,973 | $1.54M | 0.01% | −65−1.1% | Reduced |
| Oregon Public Employees Retirement Fund | 5,949 | $1.54M | 0.02% | +53+0.9% | Added |
| Fifth Third Bancorp | 5,925 | $1.53M | 0.00% | +5,779+3,958.2% | Added |
| SG Americas Securities, LLC | 5,899 | $1.52M | 0.00% | −13,010−68.8% | Reduced |
| FORA Capital, LLC | 5,732 | $1.48M | 0.11% | +3,620+171.4% | Added |
| Amundi | 5,706 | $1.47M | 0.00% | +1,952+52.0% | Added |
| Vanguard Investments Australia, Ltd. | 5,330 | $1.38M | 0.00% | +5,330 | New |
| China Universal Asset Management Co., Ltd. | 5,187 | $1.34M | 0.10% | +462+9.8% | Added |
| ProShare Advisors LLC | 5,177 | $1.34M | 0.00% | −939−15.4% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 5,139 | $1.33M | 0.00% | +1,275+33.0% | Added |
| Barclays PLC | 4,969 | $1.28M | 0.00% | −55,093−91.7% | Reduced |
| Kennedy Capital Management, Inc. | 4,904 | $1.27M | 0.03% | +403+9.0% | Added |
| Odyssean, LLC | 4,819 | $1.24M | 0.45% | +1,805+59.9% | Added |
| KLP Kapitalforvaltning AS | 4,800 | $1.24M | 0.00% | +100+2.1% | Added |
| Cookson Peirce & Co Inc | 4,694 | $1.21M | 0.05% | −1,260−21.2% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 4,664 | $1.20M | 0.00% | +4,664 | New |
| Allstate Corp | 4,433 | $1.15M | 0.01% | +4,433 | New |
| Seven Fleet Capital Management LP | 4,316 | $1.11M | 0.35% | +316+7.9% | Added |
| Millennium Management LLC | 4,119 | $1.06M | 0.00% | −10,539−71.9% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 4,104 | $1.06M | 0.02% | 00.0% | Unchanged |
| Omers Administration Corp | 4,100 | $1.06M | 0.01% | +4,100 | New |
| Regal Investment Advisors LLC | 4,050 | $1.05M | 0.06% | −310−7.1% | Reduced |
| Maryland State Retirement & Pension System | 3,764 | $972.3K | 0.02% | −10−0.3% | Reduced |
| Guggenheim Capital LLC | 3,518 | $908.8K | 0.01% | −3,734−51.5% | Reduced |
| Pier 88 Investment Partners LLC | 3,500 | $904.1K | 0.23% | −470−11.8% | Reduced |
| Virtus Investment Advisers, Inc. | 3,449 | $890.9K | 0.25% | +657+23.5% | Added |
| Ellsworth Advisors, LLC | 3,245 | $838.2K | 0.16% | +3,245 | New |
| Resona Asset Management Co.,Ltd. | 3,194 | $825.1K | 0.00% | +137+4.5% | Added |
| Quadrature Capital Ltd | 3,189 | $823.8K | 0.01% | +3,189 | New |
| Quantinno Capital Management LP | 3,171 | $819.1K | 0.00% | +267+9.2% | Added |
| CI Private Wealth, LLC | 3,523 | $818.5K | 0.00% | −34,823−90.8% | Reduced |
| Bank of Montreal | 3,162 | $816.8K | 0.00% | +931+41.7% | Added |
| Assetmark, Inc | 3,157 | $815.5K | 0.00% | +3,157 | New |
| DnB Asset Management AS | 3,100 | $800.8K | 0.00% | +7+0.2% | Added |
| JustInvest LLC | 3,027 | $781.9K | 0.01% | +900+42.3% | Added |
| Hanseatic Management Services Inc | 2,997 | $774.2K | 0.74% | +2,997 | New |
| Confluence Wealth Services, Inc. | 2,922 | $754.8K | 0.03% | 00.0% | Unchanged |
| Freestone Grove Partners LP | 2,922 | $754.8K | 0.01% | +2,922 | New |
| Cinctive Capital Management LP | 2,874 | $742.4K | 0.05% | +2,874 | New |
| Teacher Retirement System of Texas | 2,823 | $729.2K | 0.00% | −399−12.4% | Reduced |
| Citadel Advisors LLC | 2,726 | $704.2K | 0.00% | −383,779−99.3% | Reduced |
| American Century Companies Inc | 2,717 | $701.9K | 0.00% | +2,717 | New |
| Pacer Advisors, Inc. | 2,547 | $658.0K | 0.00% | +835+48.8% | Added |
| Transcend Wealth Collective, LLC | 2,511 | $648.6K | 0.05% | +831+49.5% | Added |
| Allspring Global Investments Holdings, LLC | 2,475 | $640.8K | 0.00% | +241+10.8% | Added |
| Blair William & Co | 2,448 | $632.4K | 0.00% | −729−22.9% | Reduced |
| Public Employees Retirement Association of Colorado | 2,363 | $610.0K | 0.00% | 00.0% | Unchanged |
| Xponance, Inc. | 2,339 | $604.2K | 0.00% | +380+19.4% | Added |
| Tower Research Capital LLC (TRC) | 2,318 | $598.8K | 0.02% | +632+37.5% | Added |
| Crossmark Global Holdings, Inc. | 2,294 | $592.6K | 0.01% | +170+8.0% | Added |
| E Fund Management Co., Ltd. | 2,281 | $589.2K | 0.02% | +2,281 | New |
| Empowered Funds, LLC | 2,276 | $587.9K | 0.00% | +2,276 | New |
| Blackstone Group Inc. | 2,246 | $580.2K | 0.00% | +2,246 | New |
| Pathstone Holdings, LLC | 2,241 | $578.9K | 0.00% | −40−1.8% | Reduced |
| Entropy Technologies, LP | 2,200 | $568.3K | 0.03% | −303−12.1% | Reduced |
| Janney Montgomery Scott LLC | 2,170 | $561.0K | 0.00% | −228−9.5% | Reduced |