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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
135
−4 vs. Q4 2021
Shares held
20.6M
+1.29M (+6.7%) vs. Q4 2021
Total value
$1.37B
+$17.9M (+1.3%) vs. Q4 2021
New holders
22
53 more added
Sold out
26
49 more reduced

1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 135 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ1 2022: $1.37B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2021.

Institutions holding KRYS in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC2,106,492$140.2M0.01%+128,203+6.5%Added
Redmile Group, LLC1,815,698$120.8M3.77%−5,200−0.3%Reduced
Point72 Asset Management, L.P.1,720,267$114.5M0.51%−135,889−7.3%Reduced
BlackRock Inc.1,683,511$112.0M0.00%+78,015+4.9%Added
Lord, Abbett & Co. LLC1,178,813$78.4M0.21%+4,950+0.4%Added
State Street Corp1,068,656$71.1M0.00%+366,855+52.3%Added
Vanguard Group Inc1,051,445$70.0M0.00%+27,835+2.7%Added
Avoro Capital Advisors LLC1,005,000$66.9M1.22%+530,000+111.6%Added
Frazier Life Sciences Management, L.P.866,250$57.6M4.91%+866,250New
Baker Bros. Advisors LP807,735$53.7M0.31%00.0%Unchanged
Credit Suisse AG757,859$50.4M0.04%+4,179+0.6%Added
First Light Asset Management, LLC717,936$47.8M4.21%+37,766+5.6%Added
Pictet Asset Management SA688,555$45.8M0.05%−12,848−1.8%Reduced
Artal Group S.A.500,000$33.3M1.41%−200,000−28.6%Reduced
Hood River Capital Management LLC384,810$25.6M0.85%+159,083+70.5%Added
Geode Capital Management, LLC365,290$24.3M0.00%+35,364+10.7%Added
Soleus Capital Management, L.P.289,337$19.3M2.97%+60,900+26.7%Added
Dimensional Fund Advisors LP262,463$17.5M0.01%+111,822+74.2%Added
JPMorgan Chase & Co257,861$17.2M0.00%+58,228+29.2%Added
Nicholas Investment Partners, LP228,732$15.2M1.08%+37,421+19.6%Added
C WorldWide Group Holding A/S225,809$15.0M0.16%+40,000+21.5%Added
Skandinaviska Enskilda Banken AB (publ)208,711$13.9M0.08%−115−0.1%Reduced
Northern Trust Corp194,102$12.9M0.00%+10,543+5.7%Added
Charles Schwab Investment Management Inc148,347$9.87M0.00%+8,729+6.3%Added
Goldman Sachs Group Inc136,047$9.05M0.00%+82,894+156.0%Added
Handelsbanken Fonder AB110,000$7.32M0.04%+20,000+22.2%Added
S Squared Technology, LLC108,215$7.20M3.59%+13,000+13.7%Added
Bank of New York Mellon Corp86,895$5.78M0.00%+3,444+4.1%Added
Nuveen Asset Management, LLC84,259$5.64M0.00%+6,081+7.8%Added
Morgan Stanley71,980$4.79M0.00%−39,018−35.2%Reduced
Jennison Associates LLC68,309$4.54M0.00%+68,309New
Rafferty Asset Management, LLC60,012$3.99M0.02%+27,519+84.7%Added
ACT Capital Management, LLC59,000$3.93M4.15%00.0%Unchanged
UBS Group AG58,070$3.86M0.00%+56,237+3,068.0%Added
CWM, LLC52,303$3.48M0.02%−7,632−12.7%Reduced
Silverarc Capital Management, LLC46,489$3.09M1.68%−181−0.4%Reduced
Bank of America Corp42,595$2.83M0.00%+29,386+222.5%Added
Swiss National Bank41,200$2.74M0.00%+2,800+7.3%Added
SG Americas Securities, LLC39,101$2.60M0.02%−13,369−25.5%Reduced
Parametric Portfolio Associates LLC37,070$2.47M0.00%−2,377−6.0%Reduced
Jacob Asset Management of New York LLC34,242$2.28M1.39%−16,680−32.8%Reduced
EAM Investors, LLC33,878$2.25M0.42%−989−2.8%Reduced
J. Goldman & Co LP31,859$2.12M0.16%+31,859New
Verition Fund Management LLC31,166$2.07M0.04%−44,948−59.1%Reduced
Allianz Asset Management GmbH29,880$1.99M0.00%+8,721+41.2%Added
Mutual of America Capital Management LLC28,980$1.93M0.02%−1,257−4.2%Reduced
New York State Common Retirement Fund27,066$1.80M0.00%+2,847+11.8%Added
Alps Advisors Inc25,913$1.72M0.02%−2,906−10.1%Reduced
Vontobel Holding Ltd.25,788$1.72M0.01%−1,122−4.2%Reduced
DekaBank Deutsche Girozentrale25,300$1.69M0.00%+16,500+187.5%Added
Sphera Funds Management Ltd.25,310$1.68M0.28%+25,310New
Parallel Advisors, LLC24,565$1.64M0.07%−9,471−27.8%Reduced
DnB Asset Management AS24,500$1.63M0.01%−11,140−31.3%Reduced
Rhumbline Advisers23,839$1.59M0.00%+2,172+10.0%Added
California State Teachers Retirement System23,468$1.56M0.00%−948−3.9%Reduced
State of Wisconsin Investment Board23,400$1.56M0.00%−3,800−14.0%Reduced
Alliancebernstein L.P.23,400$1.56M0.00%+2,700+13.0%Added
Hennion & Walsh Asset Management, Inc.23,368$1.55M0.08%+9,231+65.3%Added
EAM Global Investors LLC21,959$1.46M0.27%00.0%Unchanged
Prudential Financial Inc20,891$1.39M0.00%+20,891New
Jane Street Group, LLC20,327$1.35M0.00%−7,357−26.6%Reduced
SEI Investments Co19,413$1.29M0.00%+2,998+18.3%Added
Advisory Research Inc18,731$1.25M0.10%+12,392+195.5%Added
Kynam Capital Management, LP18,393$1.22M0.40%−16,423−47.2%Reduced
HighMark Wealth Management LLC17,185$1.14M0.76%00.0%Unchanged
International Biotechnology Trust PLC45,000$1.11M0.49%00.0%Unchanged
Harbor Capital Advisors, Inc.15,305$1.02M0.48%−3,167−17.1%Reduced
Citigroup Inc15,232$1.01M0.00%−19,656−56.3%Reduced
UBS Asset Management Americas Inc15,207$1.01M0.00%+5,014+49.2%Added
Deutsche Bank AG15,129$1.01M0.00%+191+1.3%Added
Susquehanna International Group, LLP15,113$1.01M0.00%+1,629+12.1%Added
Bellevue Group AG13,800$918.0K0.01%−200−1.4%Reduced
MetLife Investment Management10,266$683.1K0.00%+3,618+54.4%Added
American International Group, Inc.9,988$665.0K0.00%+457+4.8%Added
Wells Fargo & Company9,620$640.0K0.00%−5,345−35.7%Reduced
Price T Rowe Associates Inc9,473$630.0K0.00%+1,368+16.9%Added
State Board of Administration of Florida Retirement System8,777$584.0K0.00%00.0%Unchanged
Citadel Advisors LLC8,732$581.0K0.00%−30,013−77.5%Reduced
Manufacturers Life Insurance Company, The8,126$540.7K0.00%−1,201−12.9%Reduced
Invesco Ltd.7,750$515.0K0.00%+69+0.9%Added
Voya Investment Management LLC7,012$467.0K0.00%00.0%Unchanged
Legal & General Group Plc6,533$435.0K0.00%+370+6.0%Added
ProShare Advisors LLC6,378$424.0K0.00%−668−9.5%Reduced
Quantum Private Wealth, LLC6,382$424.0K0.18%−442−6.5%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.6,201$413.0K0.00%+285+4.8%Added
NinePointTwo Capital6,186$411.0K0.11%+6,186New
Erste Asset Management GmbH5,400$361.3K0.01%+5,400New
Taylor Wealth Management Partners5,365$357.0K0.14%+50+0.9%Added
Sandia Investment Management LP5,000$333.0K0.05%00.0%Unchanged
Merriman Wealth Management, LLC5,000$333.0K0.03%+5,000New
Arizona State Retirement System4,712$314.0K0.00%+827+21.3%Added
Janus Henderson Group PLC4,304$286.0K0.00%+1,395+48.0%Added
Zurcher Kantonalbank (Zurich Cantonalbank)4,125$274.0K0.00%−430−9.4%Reduced
Privium Fund Management B.V.4,000$266.0K0.06%+4,000New
STRS Ohio3,900$259.0K0.00%00.0%Unchanged
D. E. Shaw & Co., Inc.3,809$253.0K0.00%+3,809New
Franklin Resources Inc3,737$249.0K0.00%+3,737New
Allspring Global Investments Holdings, LLC3,660$243.0K0.00%+376+11.4%Added
Teacher Retirement System of Texas3,584$238.0K0.00%+3,584New
Commonwealth Equity Services, LLC3,518$234.0K0.00%+3,518New