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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
135
−4 vs. Q4 2021
Shares held
20.6M
+1.29M (+6.7%) vs. Q4 2021
Total value
$1.37B
+$17.9M (+1.3%) vs. Q4 2021
New holders
22
53 more added
Sold out
26
49 more reduced

1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 135 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ1 2022: $1.37B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2021.

Institutions holding KRYS in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Barclays PLC3,395$225.0K0.00%−22,466−86.9%Reduced
Tower Research Capital LLC (TRC)3,126$208.0K0.00%−2,473−44.2%Reduced
E Fund Management Co., Ltd.3,011$200.0K0.01%+3,011New
Amalgamated Bank2,437$162.0K0.00%+2,437New
Amalgamated Financial Corp.2,437$162.0K0.00%+2,437New
BNP Paribas Arbitrage, SA2,341$155.8K0.00%−3,145−57.3%Reduced
DuPont Capital Management Corp2,319$154.0K0.01%−206−8.2%Reduced
Virtus ETF Advisers LLC2,199$146.0K0.07%−137−5.9%Reduced
Lazard Asset Management LLC1,771$117.0K0.00%+499+39.2%Added
Ameritas Investment Partners, Inc.1,560$104.0K0.00%+154+11.0%Added
Royal Bank of Canada1,532$102.0K0.00%−2,036−57.1%Reduced
Metropolitan Life Insurance Co1,283$85.4K0.00%−3,503−73.2%Reduced
Great West Life Assurance Co1,013$72.0K0.00%+346+51.9%Added
State of Wyoming757$50.0K0.03%+244+47.6%Added
US Bancorp671$45.0K0.00%−164−19.6%Reduced
Macquarie Group Ltd628$42.0K0.00%00.0%Unchanged
Cutler Group LP300$19.0K0.00%−8,371−96.5%Reduced
Nisa Investment Advisors, LLC260$17.0K0.00%−110−29.7%Reduced
Aquatic Capital Management LLC100$7.00K0.01%−1,200−92.3%Reduced
Advisor Group Holdings, Inc.100$7.00K0.00%+96+2,400.0%Added
Global Retirement Partners, LLC125$7.00K0.00%+125New
Signaturefd, LLC93$6.00K0.00%−125−57.3%Reduced
TCI Wealth Advisors, Inc.84$6.00K0.00%−7−7.7%Reduced
Daiwa Securities Group Inc.76$5.00K0.00%00.0%Unchanged
Captrust Financial Advisors53$4.00K0.00%−16−23.2%Reduced
Money Concepts Capital Corp55$4.00K0.00%+55New
Cubist Systematic Strategies, LLC37$2.00K0.00%−4,477−99.2%Reduced
The PNC Financial Services Group, Inc.28$2.00K0.00%+26+1,300.0%Added
Federated Hermes, Inc.6$1.00K0.00%−654−99.1%Reduced
Massmutual Trust Co FSB11$1.00K0.00%+11New
Simplex Trading, LLC26$1.00K0.00%+26New
Lindbrook Capital, LLC12$1.00K0.00%+12New
Quadrant Capital Group LLC4$00.00%−17−81.0%Reduced
Covestor Ltd5$00.00%−1−16.7%Reduced
TCWP LLC7$00.00%+7New
Frazier Management LLC0$00.00%−771,250−100.0%Sold out
Marshall Wace, LLP0$00.00%−108,511−100.0%Sold out
Millennium Management LLC0$00.00%−61,429−100.0%Sold out
Caption Management, LLC0$00.00%−27,300−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−26,517−100.0%Sold out
Squarepoint Ops LLC0$00.00%−21,794−100.0%Sold out
Ergoteles LLC0$00.00%−17,002−100.0%Sold out
SG3 Management, LLC0$00.00%−14,879−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−12,562−100.0%Sold out
HRT Financial LP0$00.00%−12,110−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−11,371−100.0%Sold out
Blair William & Co0$00.00%−8,896−100.0%Sold out
Toronto Dominion Bank0$00.00%−8,108−100.0%Sold out
Rock Creek Group, LP0$00.00%−8,847−100.0%Sold out
Caas Capital Management LP0$00.00%−7,121−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−5,780−100.0%Sold out
LMR Partners LLP0$00.00%−4,884−100.0%Sold out
Pinz Capital Management, LP0$00.00%−4,500−100.0%Sold out
Truist Financial Corp0$00.00%−4,000−100.0%Sold out
Victory Capital Management Inc0$00.00%−2,864−100.0%Sold out
Widmann Financial Services, Inc.0$00.00%−500−100.0%Sold out
Group One Trading, L.P.0$00.00%−465−100.0%Sold out
Confluence Wealth Services, Inc.0$00.00%−370−100.0%Sold out
Eagle Bay Advisors LLC0$00.00%−192−100.0%Sold out
Total Clarity Wealth Management, Inc.0$00.00%−50−100.0%Sold out
Tarbox Family Office, Inc.0$00.00%−17−100.0%Sold out
Bell Investment Advisors, Inc––––Not filed