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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

Holders of 5% or more of KRYS

Holders whose latest Schedule 13D or 13G filing reports 5% or more of Krystal Biotech, Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of KRYS
HolderLatest formStakeChangeFirst filedLatest filingFiling
Krishnan Krish S13G/A11.50%3.39M shares–May 4, 20261 filingMay 4, 2026SEC
Vanguard Portfolio Management LLC13G5.05%1.48M sharesNewApr 29, 20261 filingApr 29, 2026SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

34 Schedule 13D and 13G filings on Krystal Biotech, Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on KRYS
Filed (ET)FilerFormStakeChangeEvent dateFiling
May 4, 20267:10 AM ETKrishnan Krish Sand 1 other13G/A11.50%3.39M shares–Mar 31, 2026SEC
Apr 29, 20262:16 PM ETVanguard Portfolio Management LLC13G5.05%1.48M sharesNewMar 31, 2026SEC
Mar 27, 202610:19 AM ETVanguard Group Inc13G/A0.00%0 shares–Below 5%Mar 13, 2026SEC
Feb 5, 20257:51 AM ETState Street Corp13G4.40%1.28M shares–Below 5%Dec 31, 2024SEC
Nov 14, 2024Redmile Group, LLC13G/AOld format–––SEC
Nov 12, 2024FMR LLC13G/AOld format–––SEC
Oct 16, 2024State Street Corp13GOld format–New–SEC
Jul 10, 2024Vanguard Group Inc13G/AOld format–––SEC
Jul 8, 20244:32 PM ETBlackRock Inc.13G/AOld format–––SEC
Feb 14, 2024Redmile Group, LLC13G/AOld format–––SEC
Feb 14, 2024Avoro Capital Advisors LLC13G/AOld format–––SEC
Feb 13, 2024Vanguard Group Inc13GOld format–New–SEC
Feb 12, 2024FMR LLC13G/AOld format–––SEC
Feb 9, 2024FMR LLC13G/AOld format–––SEC
Jan 29, 20243:26 PM ETBlackRock Inc.13G/AOld format–––SEC
May 10, 2023FMR LLC13G/AOld format–––SEC
Feb 14, 2023Redmile Group, LLC13G/AOld format–––SEC
Feb 14, 2023Avoro Capital Advisors LLC13GOld format–New–SEC
Feb 14, 2023Point72 Asset Management, L.P.13G/AOld format–––SEC
Feb 9, 2023FMR LLC13G/AOld format–––SEC
Jan 31, 20235:52 PM ETBlackRock Inc.13G/AOld format–––SEC
Feb 14, 2022Redmile Group, LLC13G/AOld format–––SEC
Feb 14, 2022Point72 Asset Management, L.P.13G/AOld format–––SEC
Feb 9, 2022FMR LLC13G/AOld format–––SEC
Feb 3, 20224:41 PM ETBlackRock Inc.13G/AOld format–––SEC
Dec 6, 2021Point72 Asset Management, L.P.13GOld format–New–SEC
Mar 9, 2021Sun Pharma (Netherlands) B.V.13G/AOld format–––SEC
Feb 16, 2021Baker Bros. Advisors LP13G/AOld format–––SEC
Feb 16, 2021Redmile Group, LLC13G/AOld format–––SEC
Feb 16, 2021Price T Rowe Associates Inc13G/AOld format–––SEC
Feb 12, 2021OrbiMed Advisors LLC13G/AOld format–––SEC
Feb 8, 2021FMR LLC13G/AOld format–––SEC
Feb 4, 2021Frazier Life Sciences IX, L.P.13G/AOld format–––SEC
Feb 2, 20213:13 PM ETBlackRock Inc.13GOld format–New–SEC

Form 144: proposed insider sales

10 notices from officers, directors and other affiliates planning to sell Krystal Biotech, Inc. shares, newest first.

Form 144 notices for KRYS
Filed (ET)SellerShares to sellMarket valuePlanned saleBrokerFiling
Jun 9, 20234:16 PM ETAndrew OrthOfficer12.5K$1.60MJun 9, 202310b5-1Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
Jun 8, 20234:39 PM ETJanney DanielDirector50.0K$6.40MJun 8, 2023MERRILL LYNCHSEC
May 31, 20234:30 PM ETKrish KrishnanOfficer · 10% stockholder25.0K$2.91MMay 31, 2023Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
May 31, 20234:23 PM ETSuma KrishnanOfficer · 10% stockholder25.0K$2.90MMay 31, 2023Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
May 22, 20234:35 PM ETKathryn A RomanoOfficer25.0K$2.40MMay 22, 202310b5-1Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
May 19, 20234:27 PM ETKathryn RomanoOfficer28.4K$2.49MMay 19, 202310b5-1Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
May 19, 20234:18 PM ETJanney DanielDirector50.0K$4.75MMay 19, 202310b5-1MERRILL LYNCHSEC
Apr 19, 20234:19 PM ETJanney DanielDirector25.0K$2.25MApr 19, 202310b5-1MERRILL LYNCHSEC
Apr 17, 20234:51 PM ETKrish KrishnanOfficer25.0K$2.16MApr 17, 202310b5-1Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC
Apr 17, 20234:50 PM ETSuma KrishnanOfficer25.0K$2.16MApr 17, 202310b5-1Morgan Stanley Smith Barney LLC Executive Financial ServicesSEC