Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 275
- −21 vs. Q1 2025
- Shares held
- 27.7M
- +56.6K (+0.2%) vs. Q1 2025
- Total value
- $3.80B
- −$1.17B (−23.6%) vs. Q1 2025
- New holders
- 42
- 101 more added
- Sold out
- 63
- 96 more reduced
3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| AQR Capital Management LLC | 11,968 | $1.65M | 0.00% | −163−1.3% | Reduced |
| Louisiana State Employees Retirement System | 11,900 | $1.64M | 0.03% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 11,727 | $1.61M | 0.00% | −38,165−76.5% | Reduced |
| Torray LLC | 11,574 | $1.59M | 0.23% | +11,574 | New |
| Intech Investment Management LLC | 10,978 | $1.51M | 0.01% | −1,100−9.1% | Reduced |
| State of Tennessee, Treasury Department | 10,951 | $1.51M | 0.01% | −211−1.9% | Reduced |
| Russell Investments Group, Ltd. | 10,358 | $1.42M | 0.00% | −27,423−72.6% | Reduced |
| Schroder Investment Management Group | 10,228 | $1.41M | 0.00% | −2,820−21.6% | Reduced |
| Wellington Management Group LLP | 10,153 | $1.40M | 0.00% | −446−4.2% | Reduced |
| Janus Henderson Group PLC | 10,071 | $1.38M | 0.00% | 00.0% | Unchanged |
| Yousif Capital Management, LLC | 9,600 | $1.32M | 0.01% | +30+0.3% | Added |
| Privium Fund Management B.V. | 9,320 | $1.30M | 0.28% | +1,810+24.1% | Added |
| OrbiMed Advisors LLC | 9,200 | $1.26M | 0.03% | −14,300−60.9% | Reduced |
| Perigon Wealth Management, LLC | 8,898 | $1.22M | 0.03% | +407+4.8% | Added |
| Comerica Bank | 8,708 | $1.20M | 0.00% | +7+0.1% | Added |
| Creative Planning | 8,356 | $1.15M | 0.00% | −3,730−30.9% | Reduced |
| Teachers Retirement System of the State of Kentucky | 8,329 | $1.15M | 0.01% | −681−7.6% | Reduced |
| Commonwealth Equity Services, LLC | 8,215 | $1.13M | 0.00% | +912+12.5% | Added |
| Tealwood Asset Management Inc | 8,183 | $1.13M | 0.50% | +8,183 | New |
| Profund Advisors LLC | 8,166 | $1.12M | 0.04% | +2,203+36.9% | Added |
| Virginia Retirement Systems Et Al | 7,800 | $1.07M | 0.01% | 00.0% | Unchanged |
| Maryland State Retirement & Pension System | 7,474 | $1.03M | 0.02% | +123+1.7% | Added |
| STRS Ohio | 7,400 | $1.02M | 0.00% | +500+7.2% | Added |
| Sphera Funds Management Ltd. | 7,335 | $1.01M | 0.26% | +7,335 | New |
| Amalgamated Bank | 7,226 | $993.0K | 0.01% | +26+0.4% | Added |
| Quantum Private Wealth, LLC | 7,205 | $990.4K | 0.32% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 7,183 | $987.4K | 0.00% | +2,746+61.9% | Added |
| M&G Plc | 6,748 | $924.5K | 0.01% | +6,748 | New |
| ProShare Advisors LLC | 6,625 | $910.7K | 0.00% | −526−7.4% | Reduced |
| Ensign Peak Advisors, Inc | 6,569 | $903.0K | 0.00% | 00.0% | Unchanged |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 6,529 | $897.5K | 0.00% | +472+7.8% | Added |
| Summit Trail Advisors, LLC | 6,500 | $893.5K | 0.02% | +6,500 | New |
| Shay Capital LLC | 6,500 | $893.5K | 0.20% | +6,500 | New |
| Arizona State Retirement System | 6,316 | $868.2K | 0.01% | +145+2.3% | Added |
| Guggenheim Capital LLC | 6,062 | $833.3K | 0.01% | +1,909+46.0% | Added |
| Cynosure Management, LLC | 5,918 | $813.5K | 0.09% | +2,016+51.7% | Added |
| Teacher Retirement System of Texas | 5,841 | $802.9K | 0.00% | +36+0.6% | Added |
| State Board of Administration of Florida Retirement System | 5,807 | $798.2K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 5,804 | $797.8K | 0.08% | +26+0.4% | Added |
| Oregon Public Employees Retirement Fund | 5,802 | $797.5K | 0.01% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 5,600 | $769.8K | 0.01% | +180+3.3% | Added |
| Dark Forest Capital Management LP | 5,504 | $756.6K | 0.03% | −3,933−41.7% | Reduced |
| Main Management ETF Advisors, LLC | 5,131 | $705.0K | 0.03% | +84+1.7% | Added |
| CenterBook Partners LP | 5,051 | $694.3K | 0.04% | +5,051 | New |
| Blair William & Co | 4,852 | $667.0K | 0.00% | −4,581−48.6% | Reduced |
| Summit Global Investments | 4,547 | $625.0K | 0.04% | −164−3.5% | Reduced |
| Martingale Asset Management L P | 4,505 | $619.3K | 0.02% | −631−12.3% | Reduced |
| Regal Investment Advisors LLC | 4,434 | $609.5K | 0.05% | +127+2.9% | Added |
| Bank of Montreal | 4,407 | $605.8K | 0.00% | −11−0.2% | Reduced |
| Cetera Investment Advisers | 4,344 | $597.1K | 0.00% | +2,255+107.9% | Added |
| Bryce Point Capital, LLC | 4,323 | $594.2K | 0.50% | +37+0.9% | Added |
| Amundi | 4,194 | $592.8K | 0.00% | +4,194 | New |
| KLP Kapitalforvaltning AS | 4,300 | $591.1K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 4,255 | $584.9K | 0.00% | +618+17.0% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 4,134 | $568.3K | 0.00% | −8,619−67.6% | Reduced |
| Pathstone Holdings, LLC | 3,939 | $541.5K | 0.00% | −4,170−51.4% | Reduced |
| E Fund Management Co., Ltd. | 3,870 | $532.0K | 0.03% | +1,612+71.4% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 3,864 | $531.1K | 0.00% | −1,878−32.7% | Reduced |
| Pier 88 Investment Partners LLC | 3,820 | $525.1K | 0.10% | −610−13.8% | Reduced |
| M&T Bank Corp | 3,785 | $520.4K | 0.00% | +85+2.3% | Added |
| Aviva PLC | 3,575 | $491.4K | 0.00% | +319+9.8% | Added |
| Susquehanna Portfolio Strategies, LLC | 3,539 | $486.5K | 0.01% | +3,539 | New |
| Hennion & Walsh Asset Management, Inc. | 3,253 | $447.2K | 0.02% | −6,952−68.1% | Reduced |
| Virtus Investment Advisers, Inc. | 3,167 | $435.3K | 0.15% | +1,099+53.1% | Added |
| Vontobel Holding Ltd. | 3,075 | $422.7K | 0.00% | +375+13.9% | Added |
| CIBC World Markets Corp | 3,055 | $419.9K | 0.00% | −2,449−44.5% | Reduced |
| Tower Research Capital LLC (TRC) | 2,998 | $412.1K | 0.01% | +2,268+310.7% | Added |
| Confluence Wealth Services, Inc. | 2,922 | $401.7K | 0.02% | +2+0.1% | Added |
| Resona Asset Management Co.,Ltd. | 2,917 | $401.0K | 0.00% | +2,917 | New |
| Advantage Alpha Capital Partners LP | 2,894 | $397.8K | 0.11% | −675−18.9% | Reduced |
| EP Wealth Advisors, LLC | 2,726 | $374.7K | 0.00% | +105+4.0% | Added |
| Ameritas Investment Partners, Inc. | 2,509 | $344.9K | 0.01% | 00.0% | Unchanged |
| Crossmark Global Holdings, Inc. | 2,457 | $337.7K | 0.01% | +87+3.7% | Added |
| Graham Capital Management, L.P. | 2,435 | $334.7K | 0.01% | +256+11.7% | Added |
| Tempus Wealth Planning, LLC | 2,379 | $327.0K | 0.08% | +2,379 | New |
| Public Employees Retirement Association of Colorado | 2,363 | $325.0K | 0.00% | 00.0% | Unchanged |
| Nebula Research & Development LLC | 2,355 | $323.7K | 0.03% | −3,865−62.1% | Reduced |
| Janney Montgomery Scott LLC | 2,340 | $322.0K | 0.00% | −43,595−94.9% | Reduced |
| Capstone Investment Advisors, LLC | 2,196 | $301.9K | 0.00% | +2,196 | New |
| Ballentine Partners, LLC | 2,115 | $290.7K | 0.00% | −21−1.0% | Reduced |
| Allspring Global Investments Holdings, LLC | 2,068 | $287.5K | 0.00% | −3,112−60.1% | Reduced |
| Farallon Capital Management, L.L.C. | 2,000 | $274.9K | 0.00% | 00.0% | Unchanged |
| Campbell & CO Investment Adviser LLC | 1,991 | $273.7K | 0.02% | +1,991 | New |
| Vident Advisory, LLC | 1,982 | $272.4K | 0.00% | −805−28.9% | Reduced |
| Sound View Wealth Advisors Group, LLC | 1,947 | $267.6K | 0.02% | +432+28.5% | Added |
| Aigen Investment Management, LP | 1,944 | $267.2K | 0.04% | +1,944 | New |
| Xponance, Inc. | 1,929 | $265.2K | 0.00% | +56+3.0% | Added |
| Freestone Grove Partners LP | 1,895 | $260.5K | 0.00% | +1,895 | New |
| OmniStar Financial Group, Inc. | 1,878 | $258.1K | 0.19% | −148−7.3% | Reduced |
| Parallel Advisors, LLC | 1,863 | $256.1K | 0.01% | +132+7.6% | Added |
| Royal Bank of Canada | 1,811 | $249.0K | 0.00% | +183+11.2% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,795 | $246.7K | 0.00% | +303+20.3% | Added |
| DnB Asset Management AS | 1,731 | $237.9K | 0.00% | −48−2.7% | Reduced |
| JustInvest LLC | 1,695 | $233.0K | 0.00% | −251−12.9% | Reduced |
| Mackenzie Financial Corp | 1,597 | $219.5K | 0.00% | +65+4.2% | Added |
| CWM, LLC | 1,583 | $218.0K | 0.00% | +107+7.2% | Added |
| Algert Global LLC | 1,500 | $206.2K | 0.00% | +1,500 | New |
| Hilltop Holdings Inc. | 1,468 | $201.8K | 0.01% | +272+22.7% | Added |
| The PNC Financial Services Group, Inc. | 1,422 | $195.5K | 0.00% | −719−33.6% | Reduced |
| Covestor Ltd | 1,373 | $189.0K | 0.11% | −124−8.3% | Reduced |