Skip to main content

Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
275
−21 vs. Q1 2025
Shares held
27.7M
+56.6K (+0.2%) vs. Q1 2025
Total value
$3.80B
−$1.17B (−23.6%) vs. Q1 2025
New holders
42
101 more added
Sold out
63
96 more reduced

3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 275 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ2 2025: $3.80B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2025.

Institutions holding KRYS in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Mount Yale Investment Advisors, LLC1,251$172.0K0.01%+12+1.0%Added
Bellevue Group AG1,250$171.8K0.00%−1,400−52.8%Reduced
Financiere des Professionnels - Fonds d,investissement inc.1,182$162.5K0.01%+1,182New
Mirae Asset Global Investments Co., Ltd.1,116$153.4K0.00%+152+15.8%Added
Canada Pension Plan Investment Board1,000$137.5K0.00%−300−23.1%Reduced
Avanza Fonder AB941$129.3K0.00%−319−25.3%Reduced
Nisa Investment Advisors, LLC886$121.8K0.00%−34−3.7%Reduced
GF Fund Management Co. Ltd.736$101.2K0.00%00.0%Unchanged
KBC Group NV685$94.0K0.00%−254−27.1%Reduced
Asset Management One Co.,Ltd.617$84.8K0.00%+617New
Quest Partners LLC579$79.6K0.01%−1,084−65.2%Reduced
Headlands Technologies LLC527$72.4K0.01%−483−47.8%Reduced
US Bancorp504$69.3K0.00%−135−21.1%Reduced
Pacer Advisors, Inc.455$62.5K0.00%−253−35.7%Reduced
Advisor Group Holdings, Inc.393$54.3K0.00%+115+41.4%Added
GAMMA Investing LLC285$39.2K0.00%−388−57.7%Reduced
Huntington National Bank256$35.2K0.00%+43+20.2%Added
Caldwell Trust Co250$34.4K0.00%00.0%Unchanged
First Horizon Advisors, Inc.244$33.5K0.00%+166+212.8%Added
Bryn Mawr Trust Co220$30.2K0.00%−5−2.2%Reduced
Smartleaf Asset Management LLC210$29.2K0.00%−105−33.3%Reduced
Skopos Labs, Inc.202$27.8K0.00%+61+43.3%Added
Danske Bank A/S200$27.5K0.00%+200New
Hantz Financial Services, Inc.181$25.0K0.00%+179+8,950.0%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.174$24.0K0.00%+174New
MAI Capital Management158$21.7K0.00%+24+17.9%Added
Lazard Asset Management LLC155$21.0K0.00%−249−61.6%Reduced
Key Financial Inc151$20.8K0.00%00.0%Unchanged
Daiwa Securities Group Inc.104$14.0K0.00%+9+9.5%Added
Reyes Financial Architecture, Inc.100$13.7K0.01%+100New
Fifth Third Bancorp90$12.4K0.00%−81−47.4%Reduced
Signaturefd, LLC79$10.9K0.00%−51−39.2%Reduced
Bessemer Group Inc72$10.0K0.00%+3+4.3%Added
SBI Securities Co., Ltd.70$9.62K0.00%−1−1.4%Reduced
Versant Capital Management, Inc69$9.48K0.00%+32+86.5%Added
Rise Advisors, LLC66$9.07K0.00%00.0%Unchanged
Massmutual Trust Co FSB60$8.25K0.00%+8+15.4%Added
Sterling Capital Management LLC60$8.25K0.00%+34+130.8%Added
Private Wealth Management Group, LLC55$7.56K0.00%+50+1,000.0%Added
Federation des caisses Desjardins du Quebec50$6.87K0.00%00.0%Unchanged
Allworth Financial LP44$6.05K0.00%+18+69.2%Added
Umb Bank N A43$5.91K0.00%−30−41.1%Reduced
Bare Financial Services, Inc43$5.91K0.00%+32+290.9%Added
Rothschild Investment LLC39$5.36K0.00%−7−15.2%Reduced
Twin Peaks Wealth Advisors, LLC35$5.03K0.00%+35New
GWM Advisors LLC34$4.72K0.00%00.0%Unchanged
Jones Financial Companies LLLP32$4.44K0.00%+32New
EverSource Wealth Advisors, LLC31$4.26K0.00%−24−43.6%Reduced
Clearstead Advisors, LLC24$3.30K0.00%00.0%Unchanged
Farther Finance Advisors, LLC24$3.30K0.00%+1+4.3%Added
Trust Co of Vermont20$2.75K0.00%00.0%Unchanged
Bell Investment Advisors, Inc19$2.61K0.00%00.0%Unchanged
Parkside Financial Bank & Trust15$2.06K0.00%−6−28.6%Reduced
Farmers & Merchants Investments Inc15$2.06K0.00%00.0%Unchanged
Kestra Investment Management, LLC10$1.59K0.00%+5+100.0%Added
Global Retirement Partners, LLC11$1.51K0.00%+11New
Sound Income Strategies, LLC10$1.38K0.00%00.0%Unchanged
Principal Securities, Inc.10$1.38K0.00%+3+42.9%Added
IFP Advisors, Inc10$1.37K0.00%+10New
Wolff Wiese Magana LLC8$1.10K0.00%00.0%Unchanged
Geneos Wealth Management Inc.8$1.10K0.00%00.0%Unchanged
Ronald Blue Trust, Inc.6$8250.00%−3−33.3%Reduced
SRS Capital Advisors, Inc.6$8250.00%+6New
Atlantic Trust, LLC5$6880.00%+5New
Rakuten Securities, Inc.5$6870.00%00.0%Unchanged
Glen Eagle Advisors, LLC5$6870.00%00.0%Unchanged
Fortitude Family Office, LLC4$5500.00%+4New
Hughes Financial Services, LLC4$5440.00%+4New
JFS Wealth Advisors, LLC2$2750.00%00.0%Unchanged
Larson Financial Group LLC2$2750.00%+2New
Parkworth Wealth Management, Inc.2$2750.00%+2New
Abound Wealth Management1$1380.00%00.0%Unchanged
Tradewinds Capital Management, LLC1$1380.00%+1New
Essential Partners LLC1$1370.00%+1New
Avion Wealth4$00.00%+4New
T. Rowe Price Investment Management, Inc.0$00.00%−185,550−100.0%Sold out
Lord, Abbett & Co. LLC0$00.00%−151,225−100.0%Sold out
1832 Asset Management L.P.0$00.00%−136,000−100.0%Sold out
Eventide Asset Management, LLC0$00.00%−95,781−100.0%Sold out
Squarepoint Ops LLC0$00.00%−81,999−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−60,000−100.0%Sold out
Oberweis Asset Management Inc0$00.00%−46,800−100.0%Sold out
Jennison Associates LLC0$00.00%−33,594−100.0%Sold out
Beacon Harbor Wealth Advisors, Inc.0$00.00%−32,235−100.0%Sold out
Lisanti Capital Growth, LLC0$00.00%−30,410−100.0%Sold out
Castleark Management LLC0$00.00%−26,120−100.0%Sold out
Jane Street Group, LLC0$00.00%−23,663−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−18,624−100.0%Sold out
Trexquant Investment LP0$00.00%−13,122−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−12,970−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−9,952−100.0%Sold out
Jackson Creek Investment Advisors LLC0$00.00%−8,048−100.0%Sold out
Winton Group Ltd0$00.00%−7,274−100.0%Sold out
Legato Capital Management LLC0$00.00%−5,190−100.0%Sold out
Gotham Asset Management, LLC0$00.00%−4,804−100.0%Sold out
HRT Financial LP0$00.00%−4,680−100.0%Sold out
Prime Capital Investment Advisors, LLC0$00.00%−4,504−100.0%Sold out
Eschler Asset Management LLP0$00.00%−4,403−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−4,200−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−3,883−100.0%Sold out