Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 299
- +37 vs. Q4 2024
- Shares held
- 27.6M
- +139.0K (+0.5%) vs. Q4 2024
- Total value
- $4.98B
- +$673.8M (+15.7%) vs. Q4 2024
- New holders
- 64
- 88 more added
- Sold out
- 27
- 112 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Evolutionary Tree Capital Management, LLC | 13,343 | $2.41M | 2.80% | +2,643+24.7% | Added |
| Schroder Investment Management Group | 13,048 | $2.40M | 0.00% | +441+3.5% | Added |
| Trexquant Investment LP | 13,122 | $2.37M | 0.03% | +13,122 | New |
| Corebridge Financial, Inc. | 12,970 | $2.34M | 0.01% | −255−1.9% | Reduced |
| Federated Hermes, Inc. | 12,781 | $2.30M | 0.00% | −267−2.0% | Reduced |
| Illinois Municipal Retirement Fund | 12,762 | $2.30M | 0.03% | −1,384−9.8% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 12,753 | $2.30M | 0.00% | −10,444−45.0% | Reduced |
| Envestnet Asset Management Inc | 12,399 | $2.24M | 0.00% | +769+6.6% | Added |
| AQR Capital Management LLC | 12,131 | $2.19M | 0.00% | +2,792+29.9% | Added |
| Creative Planning | 12,086 | $2.18M | 0.00% | +6,689+123.9% | Added |
| Intech Investment Management LLC | 12,078 | $2.18M | 0.02% | +1,239+11.4% | Added |
| Louisiana State Employees Retirement System | 11,900 | $2.15M | 0.04% | −300−2.5% | Reduced |
| Redwood Investments, LLC | 11,267 | $2.03M | 0.76% | −76−0.7% | Reduced |
| Renaissance Technologies LLC | 11,200 | $2.02M | 0.00% | +300+2.8% | Added |
| State of Tennessee, Treasury Department | 11,162 | $2.01M | 0.01% | −137−1.2% | Reduced |
| Wellington Management Group LLP | 10,599 | $1.91M | 0.00% | −1,105−9.4% | Reduced |
| State of New Jersey Common Pension Fund D | 10,351 | $1.87M | 0.01% | −1,452−12.3% | Reduced |
| Janus Henderson Group PLC | 10,071 | $1.85M | 0.00% | 00.0% | Unchanged |
| Hennion & Walsh Asset Management, Inc. | 10,205 | $1.84M | 0.08% | −3,473−25.4% | Reduced |
| ExodusPoint Capital Management, LP | 9,952 | $1.79M | 0.02% | +191+2.0% | Added |
| Yousif Capital Management, LLC | 9,570 | $1.73M | 0.02% | −207−2.1% | Reduced |
| Dark Forest Capital Management LP | 9,437 | $1.70M | 0.08% | +9,437 | New |
| Blair William & Co | 9,433 | $1.70M | 0.01% | +1,990+26.7% | Added |
| Teachers Retirement System of the State of Kentucky | 9,010 | $1.62M | 0.01% | 00.0% | Unchanged |
| Comerica Bank | 8,701 | $1.57M | 0.01% | −189−2.1% | Reduced |
| Perigon Wealth Management, LLC | 8,491 | $1.53M | 0.04% | +202+2.4% | Added |
| Pathstone Holdings, LLC | 8,109 | $1.46M | 0.01% | +3,857+90.7% | Added |
| Jackson Creek Investment Advisors LLC | 8,048 | $1.45M | 0.46% | −40.0% | Reduced |
| Virginia Retirement Systems Et Al | 7,800 | $1.41M | 0.01% | +7,800 | New |
| Privium Fund Management B.V. | 7,510 | $1.35M | 0.35% | −1,740−18.8% | Reduced |
| Maryland State Retirement & Pension System | 7,351 | $1.33M | 0.03% | −1,172−13.8% | Reduced |
| Commonwealth Equity Services, LLC | 7,303 | $1.32M | 0.00% | +2,437+50.1% | Added |
| Winton Group Ltd | 7,274 | $1.31M | 0.08% | +709+10.8% | Added |
| Quantum Private Wealth, LLC | 7,205 | $1.30M | 0.49% | 00.0% | Unchanged |
| Amalgamated Bank | 7,200 | $1.30M | 0.01% | −236−3.2% | Reduced |
| ProShare Advisors LLC | 7,151 | $1.29M | 0.00% | −1,697−19.2% | Reduced |
| STRS Ohio | 6,900 | $1.24M | 0.01% | −400−5.5% | Reduced |
| Ensign Peak Advisors, Inc | 6,569 | $1.18M | 0.00% | 00.0% | Unchanged |
| Nebula Research & Development LLC | 6,220 | $1.12M | 0.10% | +3,550+133.0% | Added |
| Arizona State Retirement System | 6,171 | $1.11M | 0.01% | −71−1.1% | Reduced |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 6,057 | $1.09M | 0.01% | +654+12.1% | Added |
| Profund Advisors LLC | 5,963 | $1.08M | 0.05% | −358−5.7% | Reduced |
| State Board of Administration of Florida Retirement System | 5,807 | $1.05M | 0.00% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 5,805 | $1.05M | 0.00% | −578−9.1% | Reduced |
| Oregon Public Employees Retirement Fund | 5,802 | $1.05M | 0.02% | −173−2.9% | Reduced |
| China Universal Asset Management Co., Ltd. | 5,778 | $1.04M | 0.10% | −320−5.2% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 5,742 | $1.04M | 0.00% | −312−5.2% | Reduced |
| CIBC World Markets Corp | 5,504 | $992.4K | 0.01% | +3,183+137.1% | Added |
| Police & Firemen's Retirement System of New Jersey | 5,420 | $977.2K | 0.01% | +137+2.6% | Added |
| Legato Capital Management LLC | 5,190 | $935.8K | 0.13% | +5,190 | New |
| Martingale Asset Management L P | 5,136 | $926.0K | 0.02% | 00.0% | Unchanged |
| Main Management ETF Advisors, LLC | 5,047 | $910.0K | 0.06% | +1,487+41.8% | Added |
| Allspring Global Investments Holdings, LLC | 5,180 | $904.3K | 0.00% | −24,597−82.6% | Reduced |
| Gotham Asset Management, LLC | 4,804 | $866.2K | 0.01% | +4,804 | New |
| Summit Global Investments | 4,711 | $849.0K | 0.06% | +1,258+36.4% | Added |
| HRT Financial LP | 4,680 | $843.0K | 0.01% | −17,327−78.7% | Reduced |
| Prime Capital Investment Advisors, LLC | 4,504 | $812.1K | 0.01% | +4,504 | New |
| BNP Paribas Arbitrage, SA | 4,437 | $800.0K | 0.00% | −3,352−43.0% | Reduced |
| Pier 88 Investment Partners LLC | 4,430 | $798.7K | 0.15% | +680+18.1% | Added |
| Bank of Montreal | 4,418 | $796.6K | 0.00% | +1,093+32.9% | Added |
| Eschler Asset Management LLP | 4,403 | $793.9K | 2.01% | +4,403 | New |
| Bryce Point Capital, LLC | 4,286 | $789.7K | 0.59% | +4,286 | New |
| Regal Investment Advisors LLC | 4,307 | $776.6K | 0.06% | +4,307 | New |
| KLP Kapitalforvaltning AS | 4,300 | $775.3K | 0.00% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 4,200 | $757.3K | 0.01% | +4,200 | New |
| Guggenheim Capital LLC | 4,153 | $748.8K | 0.01% | −709−14.6% | Reduced |
| Cynosure Management, LLC | 3,902 | $703.5K | 0.10% | +272+7.5% | Added |
| Quadrant Capital Group LLC | 3,883 | $700.1K | 0.03% | +3,726+2,373.2% | Added |
| Fred Alger Management, LLC | 3,728 | $672.2K | 0.00% | +3,728 | New |
| Allianz Asset Management GmbH | 3,715 | $669.8K | 0.00% | −387−9.4% | Reduced |
| M&T Bank Corp | 3,700 | $667.2K | 0.00% | +3,700 | New |
| Mariner, LLC | 3,637 | $655.8K | 0.00% | +262+7.8% | Added |
| Roman Butler Fullerton & Co | 3,867 | $654.0K | 0.25% | +3,867 | New |
| Advantage Alpha Capital Partners LP | 3,569 | $643.5K | 0.16% | +3,569 | New |
| Jain Global LLC | 3,442 | $620.6K | 0.01% | −1,358−28.3% | Reduced |
| Aviva PLC | 3,256 | $587.1K | 0.00% | +3,256 | New |
| Jump Financial, LLC | 2,983 | $537.8K | 0.01% | +2,983 | New |
| HSBC Holdings PLC | 2,875 | $507.9K | 0.00% | −1,644−36.4% | Reduced |
| Vident Advisory, LLC | 2,787 | $502.5K | 0.01% | +295+11.8% | Added |
| Aster Capital Management (DIFC) Ltd | 2,776 | $497.6K | 0.09% | +2,776 | New |
| Scientech Research LLC | 2,737 | $493.5K | 0.13% | +2,737 | New |
| Vontobel Holding Ltd. | 2,700 | $486.8K | 0.00% | −284−9.5% | Reduced |
| Confluence Wealth Services, Inc. | 2,920 | $484.1K | 0.03% | 00.0% | Unchanged |
| Bellevue Group AG | 2,650 | $477.8K | 0.01% | −2,397−47.5% | Reduced |
| EP Wealth Advisors, LLC | 2,621 | $472.6K | 0.00% | +2,621 | New |
| Camden Capital, LLC | 2,585 | $466.1K | 0.05% | +1,220+89.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 2,582 | $465.5K | 0.00% | +2,582 | New |
| Ameritas Investment Partners, Inc. | 2,509 | $452.4K | 0.02% | −86−3.3% | Reduced |
| Crossmark Global Holdings, Inc. | 2,370 | $427.3K | 0.01% | +63+2.7% | Added |
| Public Employees Retirement Association of Colorado | 2,363 | $426.0K | 0.00% | 00.0% | Unchanged |
| Fox Run Management, L.L.C. | 2,354 | $424.4K | 0.07% | +193+8.9% | Added |
| Entropy Technologies, LP | 2,300 | $414.7K | 0.04% | −1,200−34.3% | Reduced |
| E Fund Management Co., Ltd. | 2,258 | $407.1K | 0.02% | +324+16.8% | Added |
| Susquehanna Fundamental Investments, LLC | 2,242 | $404.2K | 0.01% | +2,242 | New |
| Graham Capital Management, L.P. | 2,179 | $392.9K | 0.01% | +97+4.7% | Added |
| The PNC Financial Services Group, Inc. | 2,141 | $386.0K | 0.00% | +461+27.4% | Added |
| Ballentine Partners, LLC | 2,136 | $385.1K | 0.01% | −9−0.4% | Reduced |
| Cetera Investment Advisers | 2,089 | $376.6K | 0.00% | −87−4.0% | Reduced |
| Virtus Investment Advisers, Inc. | 2,068 | $372.9K | 0.10% | +2,068 | New |
| OmniStar Financial Group, Inc. | 2,026 | $365.3K | 0.29% | +2,026 | New |