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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
154
+8 vs. Q3 2022
Shares held
20.9M
+147.3K (+0.7%) vs. Q3 2022
Total value
$1.66B
+$208.7M (+14.4%) vs. Q3 2022
New holders
18
62 more added
Sold out
10
50 more reduced

2 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 154 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ4 2022: $1.66B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2022.

Institutions holding KRYS in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd2$00.00%00.0%Unchanged
Schubert & Co1$790.00%−1−50.0%Reduced
JFS Wealth Advisors, LLC1$790.00%+1New
Disciplined Investments, LLC1$790.00%+1New
Allworth Financial LP2$1580.00%00.0%Unchanged
Federated Hermes, Inc.6$4750.00%00.0%Unchanged
GWM Advisors LLC6,387$5060.00%+29+0.5%Added
Massmutual Trust Co FSB11$1.00K0.00%00.0%Unchanged
Belpointe Asset Management LLC41$3.25K0.00%+41New
Lindbrook Capital, LLC51$4.04K0.00%+41+410.0%Added
TCI Wealth Advisors, Inc.85$6.73K0.00%+1+1.2%Added
Daiwa Securities Group Inc.96$8.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.115$9.00K0.00%+6+5.5%Added
Global Retirement Partners, LLC125$9.90K0.00%00.0%Unchanged
Ellevest, Inc.130$10.3K0.00%−8−5.8%Reduced
HealthInvest Partners AB139$11.0K0.02%+139New
Signaturefd, LLC174$13.8K0.00%+64+58.2%Added
US Bancorp192$15.2K0.00%−48−20.0%Reduced
Cutler Group LP225$17.0K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.248$19.6K0.00%+70+39.3%Added
China Universal Asset Management Co., Ltd.262$20.8K0.01%+22+9.2%Added
Lazard Asset Management LLC368$28.0K0.00%−1,482−80.1%Reduced
Tower Research Capital LLC (TRC)385$31.0K0.00%−3,092−88.9%Reduced
Allspring Global Investments Holdings, LLC961$76.1K0.00%−20−2.0%Reduced
Great West Life Assurance Co1,013$81.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC1,077$85.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co1,283$101.6K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.1,707$136.2K0.01%+147+9.4%Added
Virtus ETF Advisers LLC1,804$142.9K0.07%−267−12.9%Reduced
Ethic Inc.2,629$208.3K0.01%+2,629New
Amalgamated Bank3,025$240.0K0.00%+81+2.8%Added
Royal Bank of Canada3,058$243.0K0.00%+2,640+631.6%Added
E Fund Management Co., Ltd.3,228$256.0K0.02%−363−10.1%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.3,249$257.4K0.00%−1,179−26.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)3,257$258.0K0.00%−832−20.3%Reduced
AQR Capital Management LLC3,708$293.7K0.00%+3,708New
Natixis4,000$316.9K0.00%+4,000New
STRS Ohio4,100$324.0K0.00%00.0%Unchanged
Wells Fargo & Company4,270$338.3K0.00%−647−13.2%Reduced
Commonwealth Equity Services, LLC4,316$341.0K0.00%−5−0.1%Reduced
Janus Henderson Group PLC4,524$358.1K0.00%+4,524New
Franklin Resources Inc4,632$366.9K0.00%+25+0.5%Added
ProShare Advisors LLC4,873$386.0K0.00%+362+8.0%Added
Arizona State Retirement System5,069$401.6K0.00%+193+4.0%Added
Prudential Financial Inc5,096$403.7K0.00%−2,795−35.4%Reduced
Brookfield Asset Management Inc.5,133$406.6K0.00%+5,133New
Mariner, LLC5,145$408.0K0.00%+1,136+28.3%Added
Teacher Retirement System of Texas5,404$428.0K0.00%−490−8.3%Reduced
Capital Impact Advisors, LLC5,419$429.3K0.42%+269+5.2%Added
Erste Asset Management GmbH5,400$431.5K0.01%00.0%Unchanged
Principal Financial Group Inc5,653$447.8K0.00%+264+4.9%Added
HRT Financial LP5,694$451.0K0.01%+5,694New
D. E. Shaw & Co., Inc.6,400$507.0K0.00%−1,700−21.0%Reduced
Jacob Asset Management of New York LLC6,937$549.5K0.67%+3,175+84.4%Added
Blair William & Co6,957$551.1K0.00%+580+9.1%Added
Legal & General Group Plc7,120$564.0K0.00%+155+2.2%Added
Quantum Private Wealth, LLC7,205$570.8K0.36%00.0%Unchanged
State Board of Administration of Florida Retirement System7,307$578.9K0.00%−420−5.4%Reduced
Public Employees Retirement Association of Colorado7,818$619.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP8,192$649.0K0.00%−12,058−59.5%Reduced
Balyasny Asset Management LLC8,376$663.5K0.00%+8,376New
Manufacturers Life Insurance Company, The8,485$672.2K0.00%+150+1.8%Added
Harbor Capital Advisors, Inc.8,501$673.4K0.67%−3,276−27.8%Reduced
Privium Fund Management B.V.8,680$693.5K0.26%+1,418+19.5%Added
Price T Rowe Associates Inc9,922$786.0K0.00%−272−2.7%Reduced
American International Group, Inc.10,092$799.5K0.01%−37−0.4%Reduced
Mirae Asset Global Investments Co., Ltd.10,201$808.1K0.00%+10,201New
Advisory Research Inc10,354$820.2K0.08%−465−4.3%Reduced
Legato Capital Management LLC10,940$866.7K0.17%+10,940New
HighVista Strategies LLC11,058$876.0K0.52%+4,023+57.2%Added
MetLife Investment Management11,181$885.8K0.01%00.0%Unchanged
Marshall Wace, LLP12,200$966.5K0.00%+12,200New
Allianz Asset Management GmbH12,400$982.3K0.00%−50−0.4%Reduced
BNP Paribas Arbitrage, SA12,804$1.01M0.00%−9,076−41.5%Reduced
Deutsche Bank AG13,416$1.06M0.00%+1,165+9.5%Added
Martingale Asset Management L P13,608$1.08M0.02%+9,005+195.6%Added
Ergoteles LLC14,108$1.12M0.04%+14,108New
Vontobel Holding Ltd.14,680$1.16M0.01%−3,188−17.8%Reduced
Millennium Management LLC15,123$1.20M0.00%+15,123New
UBS Asset Management Americas Inc15,471$1.23M0.00%−701−4.3%Reduced
Parallel Advisors, LLC16,122$1.28M0.06%−5,236−24.5%Reduced
SEI Investments Co16,510$1.31M0.00%−380−2.2%Reduced
Connor, Clark & Lunn Investment Management Ltd.16,591$1.31M0.01%−7,889−32.2%Reduced
HighMark Wealth Management LLC17,185$1.36M1.03%00.0%Unchanged
Alps Advisors Inc17,444$1.38M0.01%+3,403+24.2%Added
State of Wisconsin Investment Board17,539$1.39M0.00%−208−1.2%Reduced
Bellevue Group AG18,300$1.45M0.02%00.0%Unchanged
Qube Research & Technologies Ltd19,224$1.52M0.01%+19,224New
J. Goldman & Co LP19,319$1.53M0.11%+9,392+94.6%Added
EAM Global Investors LLC21,605$1.71M0.44%00.0%Unchanged
Bank of Montreal21,698$1.76M0.00%+60+0.3%Added
EFG Asset Management (North America) Corp.22,016$1.76M0.40%+4,315+24.4%Added
Norges Bank23,083$1.83M0.00%+9,557+70.7%Added
California State Teachers Retirement System24,136$1.91M0.00%+270+1.1%Added
Kennedy Capital Management, Inc.25,820$2.05M0.06%−1,465−5.4%Reduced
Alliancebernstein L.P.26,100$2.07M0.00%+600+2.4%Added
Mutual of America Capital Management LLC26,728$2.12M0.03%+365+1.4%Added
Invesco Ltd.28,043$2.22M0.00%−23,565−45.7%Reduced
Citigroup Inc28,760$2.28M0.00%−21,063−42.3%Reduced
New York State Common Retirement Fund29,139$2.31M0.00%−80.0%Reduced