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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
194
+9 vs. Q3 2023
Shares held
24.4M
+670.7K (+2.8%) vs. Q3 2023
Total value
$3.03B
+$274.6M (+10.0%) vs. Q3 2023
New holders
29
72 more added
Sold out
20
66 more reduced

3 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 194 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ4 2023: $3.03B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2023.

Institutions holding KRYS in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Royal Bank of Canada11,327$1.41M0.00%+4,078+56.3%Added
American International Group, Inc.10,744$1.33M0.01%−43−0.4%Reduced
Evolutionary Tree Capital Management, LLC10,572$1.31M1.45%+10,572New
EFG Asset Management (North America) Corp.10,196$1.26M0.24%−6,038−37.2%Reduced
Los Angeles Capital Management LLC9,585$1.19M0.00%−538−5.3%Reduced
Janus Henderson Group PLC8,796$1.09M0.00%−12−0.1%Reduced
Vontobel Holding Ltd.8,693$1.08M0.01%−41−0.5%Reduced
Millennium Management LLC8,521$1.06M0.00%+8,521New
Citadel Advisors LLC8,199$1.02M0.00%+3,809+86.8%Added
Susquehanna International Group, LLP8,042$997.7K0.00%+898+12.6%Added
Bellevue Group AG8,000$992.5K0.02%−4,500−36.0%Reduced
Wells Fargo & Company7,560$937.9K0.00%−12,433−62.2%Reduced
Gilder Gagnon Howe & Co LLC7,527$933.8K0.01%−10.0%Reduced
Quantum Private Wealth, LLC7,205$893.9K0.37%00.0%Unchanged
Ensign Peak Advisors, Inc6,900$856.0K0.00%00.0%Unchanged
Privium Fund Management B.V.6,610$826.0K0.23%+1,400+26.9%Added
HealthInvest Partners AB6,624$821.8K0.64%+6,624New
Harbor Capital Advisors, Inc.6,262$776.9K0.15%+1,148+22.4%Added
State Board of Administration of Florida Retirement System6,167$765.1K0.00%00.0%Unchanged
Blair William & Co6,152$763.2K0.00%+20+0.3%Added
Principal Financial Group Inc5,799$719.4K0.00%+31+0.5%Added
Capital Impact Advisors, LLC5,726$710.4K0.93%00.0%Unchanged
Advisory Research Inc5,667$703.0K0.11%−3,322−37.0%Reduced
STRS Ohio5,600$694.0K0.00%−800−12.5%Reduced
Guggenheim Capital LLC5,439$674.8K0.01%+5,439New
J. Goldman & Co LP5,408$670.9K0.04%−29,805−84.6%Reduced
ProShare Advisors LLC5,379$667.3K0.00%+740+16.0%Added
CenterBook Partners LP5,335$661.9K0.08%+1,020+23.6%Added
Jefferies Financial Group Inc.5,138$637.4K0.01%+5,138New
Legato Capital Management LLC5,099$632.6K0.08%−5,841−53.4%Reduced
Arizona State Retirement System5,087$631.1K0.00%−9−0.2%Reduced
Qube Research & Technologies Ltd4,954$614.6K0.00%−8,156−62.2%Reduced
Perigon Wealth Management, LLC4,874$604.7K0.02%+791+19.4%Added
Commonwealth Equity Services, LLC4,584$569.0K0.00%+158+3.6%Added
E Fund Management Co., Ltd.4,495$557.6K0.04%+808+21.9%Added
Zurcher Kantonalbank (Zurich Cantonalbank)4,465$553.9K0.00%−22−0.5%Reduced
Allianz Asset Management GmbH4,400$545.9K0.00%00.0%Unchanged
New York Life Investment Management LLC4,314$535.2K0.01%−126−2.8%Reduced
AQR Capital Management LLC4,302$533.7K0.00%+288+7.2%Added
Teacher Retirement System of Texas4,198$521.0K0.00%−890−17.5%Reduced
Parallel Advisors, LLC4,046$501.9K0.01%−125−3.0%Reduced
Mariner, LLC3,760$466.5K0.00%−130−3.3%Reduced
Squarepoint Ops LLC3,709$460.1K0.00%+3,709New
Fox Run Management, L.L.C.3,436$426.3K0.11%+1,544+81.6%Added
China Universal Asset Management Co., Ltd.3,259$404.3K0.08%+2,541+353.9%Added
Public Employees Retirement Association of Colorado3,186$395.0K0.00%−448−12.3%Reduced
Amalgamated Bank3,103$385.0K0.00%−217−6.5%Reduced
Confluence Wealth Services, Inc.2,920$362.3K0.04%00.0%Unchanged
Envestnet Asset Management Inc2,632$326.5K0.00%−1,006−27.7%Reduced
Keybank National Association2,544$315.6K0.00%+2,544New
Prime Capital Investment Advisors, LLC2,498$309.9K0.00%+2,498New
Capstone Investment Advisors, LLC2,445$303.3K0.01%+2,445New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.2,345$278.8K0.00%−662−22.0%Reduced
Ameritas Investment Partners, Inc.2,237$277.5K0.01%+90+4.2%Added
Ballentine Partners, LLC2,080$258.0K0.01%00.0%Unchanged
Farallon Capital Management, L.L.C.2,000$248.1K0.00%00.0%Unchanged
Great West Life Assurance Co1,731$213.0K0.00%00.0%Unchanged
Ethic Inc.1,658$205.7K0.01%−185−10.0%Reduced
LPL Financial LLC1,655$205.3K0.00%+1,655New
US Bancorp1,624$201.5K0.00%+1,435+759.3%Added
Tower Research Capital LLC (TRC)1,256$155.8K0.00%−350−21.8%Reduced
Metropolitan Life Insurance Co1,246$154.6K0.01%00.0%Unchanged
Pier 88 Investment Partners LLC1,170$145.2K0.04%+1,170New
Quest Partners LLC1,022$126.8K0.03%+1,022New
Lazard Asset Management LLC1,026$125.0K0.00%+19+1.9%Added
Nisa Investment Advisors, LLC827$102.6K0.00%−100−10.8%Reduced
PEAK6 Investments LLC797$98.9K0.00%+797New
Virtus ETF Advisers LLC796$98.8K0.06%+30+3.9%Added
Advisor Group Holdings, Inc.725$89.9K0.00%−204−22.0%Reduced
Covestor Ltd593$74.0K0.05%+45+8.2%Added
KBC Group NV473$59.0K0.00%00.0%Unchanged
West Tower Group, LLC431$53.5K0.11%+347+413.1%Added
The PNC Financial Services Group, Inc.320$39.7K0.00%−100−23.8%Reduced
IFP Advisors, Inc260$32.2K0.00%+229+738.7%Added
Comerica Bank204$25.3K0.00%+71+53.4%Added
Cutler Group LP200$24.0K0.00%+100+100.0%Added
Liberty One Investment Management, LLC151$18.7K0.00%+52+52.5%Added
Daiwa Securities Group Inc.115$14.0K0.00%+19+19.8%Added
Signaturefd, LLC97$12.0K0.00%−47−32.6%Reduced
Northwestern Mutual Wealth Management Co52$6.45K0.00%+52New
Federation des caisses Desjardins du Quebec50$6.20K0.00%00.0%Unchanged
Quadrant Capital Group LLC45$5.58K0.00%+10+28.6%Added
GAMMA Investing LLC42$4.67K0.00%+42New
Lindbrook Capital, LLC36$4.47K0.00%−2−5.3%Reduced
GWM Advisors LLC34$4.26K0.00%00.0%Unchanged
Private Trust Co NA32$3.97K0.00%+9+39.1%Added
Farther Finance Advisors, LLC19$2.36K0.00%+16+533.3%Added
Massmutual Trust Co FSB17$2.11K0.00%00.0%Unchanged
Huntington National Bank9$1.12K0.00%00.0%Unchanged
Versant Capital Management, Inc8$9920.00%00.0%Unchanged
Private Wealth Management Group, LLC5$6210.00%+5New
Allworth Financial LP2$2490.00%00.0%Unchanged
JFS Wealth Advisors, LLC2$2490.00%00.0%Unchanged
Advisory Services Network, LLC2$2480.00%+2New
Silverarc Capital Management, LLC0$00.00%−71,531−100.0%Sold out
EAM Global Investors LLC0$00.00%−29,517−100.0%Sold out
Empowered Funds, LLC0$00.00%−24,611−100.0%Sold out
Apis Capital Advisors, LLC0$00.00%−24,000−100.0%Sold out
Alps Advisors Inc0$00.00%−20,620−100.0%Sold out
EAM Investors, LLC0$00.00%−16,091−100.0%Sold out