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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Fulcrum Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
154
−14 vs. Q1 2026
Shares held
79.5M
+7.79M (+10.9%) vs. Q1 2026
Total value
$291.3M
−$258.8M (−47.0%) vs. Q1 2026
New holders
28
72 more added
Sold out
42
35 more reduced

1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 154 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ2 2026: $291.3M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding FULC in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Fiduciary Trust Co136,555$499.8K0.01%00.0%Unchanged
Gsa Capital Partners LLP143,911$527.0K0.03%+7,247+5.3%Added
Simplify Asset Management Inc.153,794$562.9K0.01%+37,800+32.6%Added
Bank of New York Mellon Corp154,513$565.5K0.00%+4,571+3.0%Added
Nuveen, LLC154,871$566.8K0.00%+25,253+19.5%Added
American Century Companies Inc155,868$570.5K0.00%−374−0.2%Reduced
Alliancebernstein L.P.83,370$639.4K0.00%+48,800+141.2%Added
Morgan Stanley184,192$674.1K0.00%+10,855+6.3%Added
Quadrature Capital Ltd189,119$692.2K0.01%+189,119New
XTX Topco Ltd209,247$765.8K0.01%+137,644+192.2%Added
EntryPoint Capital, LLC217,199$794.9K0.19%+171,951+380.0%Added
Hennion & Walsh Asset Management, Inc.233,851$855.9K0.02%+233,851New
Engineers Gate Manager LP242,000$885.7K0.01%+115,891+91.9%Added
Wellington Management Group LLP285,084$1.04M0.00%+166,484+140.4%Added
Peapod Lane Capital LLC285,798$1.05M0.71%+285,798New
Bessemer Group Inc286,988$1.05M0.00%00.0%Unchanged
Boothbay Fund Management, LLC303,988$1.11M0.02%00.0%Unchanged
Vanguard Fiduciary Trust Co345,648$1.27M0.00%+15,764+4.8%Added
Charles Schwab Investment Management Inc433,220$1.59M0.00%+6,351+1.5%Added
Northern Trust Corp487,869$1.79M0.00%+14,884+3.1%Added
Point72 Asset Management, L.P.651,427$2.38M0.00%−1,423,428−68.6%Reduced
Y-Intercept (Hong Kong) Ltd681,832$2.50M0.05%+528,488+344.6%Added
Balyasny Asset Management LLC692,372$2.53M0.00%−1,087,574−61.1%Reduced
Connor, Clark & Lunn Investment Management Ltd.745,317$2.73M0.01%+8,633+1.2%Added
Vanguard Portfolio Management LLC782,144$2.86M0.00%+182,765+30.5%Added
Two Sigma Investments, LP812,766$2.97M0.00%+673,766+484.7%Added
Assenagon Asset Management S.A.835,204$3.06M0.00%−358,669−30.0%Reduced
Dimensional Fund Advisors LP960,547$3.52M0.00%−169,734−15.0%Reduced
Jump Financial, LLC1,005,000$3.68M0.03%+635,195+171.8%Added
Acadian Asset Management LLC1,038,797$3.79M0.00%+311,482+42.8%Added
Bank of America Corp1,043,029$3.82M0.00%+916,470+724.1%Added
Ikarian Capital, LLC1,049,161$3.84M0.63%00.0%Unchanged
Goldman Sachs Group Inc1,094,425$4.01M0.00%+522,516+91.4%Added
AQR Capital Management LLC1,103,261$4.04M0.00%+560,096+103.1%Added
Susquehanna International Group, LLP1,180,946$4.32M0.00%+1,079,610+1,065.4%Added
UBS Group AG1,253,909$4.59M0.00%+938,724+297.8%Added
Marshall Wace, LLP1,358,423$4.97M0.00%+1,358,423New
Geode Capital Management, LLC1,432,133$5.24M0.00%−54,409−3.7%Reduced
Millennium Management LLC1,485,803$5.44M0.00%+1,129,332+316.8%Added
ADAR1 Capital Management, LLC1,565,029$5.73M0.27%+1,434,469+1,098.7%Added
Renaissance Technologies LLC1,647,800$6.03M0.01%+1,634,200+12,016.2%Added
Qube Research & Technologies Ltd1,748,467$6.40M0.01%+773,728+79.4%Added
GSK plc1,785,714$6.54M1.09%00.0%Unchanged
Adage Capital Partners GP, L.L.C.2,000,000$7.32M0.01%+1,600,000+400.0%Added
State Street Corp2,037,025$7.46M0.00%+487,174+31.4%Added
Jane Street Group, LLC2,217,498$8.12M0.01%+1,907,081+614.4%Added
Vanguard Capital Management LLC2,697,216$9.87M0.00%+4,268+0.2%Added
Citadel Advisors LLC2,704,505$9.90M0.01%+1,412,019+109.2%Added
D. E. Shaw & Co., Inc.3,044,385$11.1M0.01%+1,421,104+87.5%Added
Suvretta Capital Management, LLC3,680,921$13.5M0.28%−2,880,190−43.9%Reduced
Nantahala Capital Management, LLC5,475,040$20.0M1.21%+2,425,000+79.5%Added
Tang Capital Management LLC6,521,412$23.9M1.08%+6,521,412New
EcoR1 Capital, LLC6,549,866$24.0M1.19%+6,549,866New
BlackRock, Inc.8,824,259$32.3M0.00%+3,433,666+63.7%Added
Ra Capital Management, L.P.0$00.00%−6,053,960−100.0%Sold out
TCG Crossover Management, LLC0$00.00%−5,250,000−100.0%Sold out
Braidwell LP0$00.00%−3,134,922−100.0%Sold out
Siren, L.L.C.0$00.00%−2,350,000−100.0%Sold out
First Turn Management, LLC0$00.00%−2,256,109−100.0%Sold out
Standard Life Aberdeen plc0$00.00%−2,211,953−100.0%Sold out
Jones Hill Capital LP0$00.00%−1,771,926−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−1,328,449−100.0%Sold out
Vestal Point Capital, LP0$00.00%−1,100,000−100.0%Sold out
Trexquant Investment LP0$00.00%−453,529−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−419,949−100.0%Sold out
DAFNA Capital Management LLC0$00.00%−205,000−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−154,435−100.0%Sold out
Atom Investors LP0$00.00%−69,155−100.0%Sold out
Burkehill Global Management, LP0$00.00%−50,000−100.0%Sold out
Man Group plc0$00.00%−46,119−100.0%Sold out
Marex Group plc0$00.00%−42,000−100.0%Sold out
Simplex Trading, LLC0$00.00%−41,940−100.0%Sold out
BIT Capital GmbH0$00.00%−40,000−100.0%Sold out
Matisse Capital0$00.00%−39,649−100.0%Sold out
Woodline Partners LP0$00.00%−30,793−100.0%Sold out
Pale Fire Capital SE0$00.00%−26,100−100.0%Sold out
Quantinno Capital Management LP0$00.00%−25,669−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−23,172−100.0%Sold out
Virtus Investment Advisers, Inc.0$00.00%−20,974−100.0%Sold out
DRW Securities, LLC0$00.00%−16,414−100.0%Sold out
Bailard, Inc.0$00.00%−11,781−100.0%Sold out
ProShare Advisors LLC0$00.00%−11,656−100.0%Sold out
Entropy Technologies, LP0$00.00%−10,819−100.0%Sold out
Clear Street Markets LLC0$00.00%−6,975−100.0%Sold out
MAI Capital Management0$00.00%−1,866−100.0%Sold out
State of Wyoming0$00.00%−1,815−100.0%Sold out
Versant Capital Management, Inc0$00.00%−858−100.0%Sold out
Massmutual Trust Co FSB0$00.00%−581−100.0%Sold out
Larson Financial Group LLC0$00.00%−407−100.0%Sold out
UMA Financial Services, Inc.0$00.00%−283−100.0%Sold out
Twin Peaks Wealth Advisors, LLC0$00.00%−38−100.0%Sold out
US Bancorp0$00.00%−26−100.0%Sold out
JPL Wealth Management, LLC0$00.00%−17−100.0%Sold out
Root Financial Partners, LLC0$00.00%−14−100.0%Sold out
Keating Financial Advisory Services, Inc.0$00.00%−3−100.0%Sold out
Hughes Financial Services, LLC0$00.00%−1−100.0%Sold out
CWM, LLC––––Not filed