Fulcrum Therapeutics, Inc.

FULC

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001680581

SEC filings (opens in a new tab)

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

Q2 2026 vs. Q1 2026

How the institutions holding Fulcrum Therapeutics, Inc. changed between Q1 2026 and Q2 2026.

All holders in Q2 2026 All holders in Q1 2026

13F holders of FULC: Q1 2026 compared with Q2 2026
Measure	Q1 2026	Of which not filed for Q2 2026	Q2 2026	Change
Holders	169	1	154	−14
Shares	71.7M	12.1K	79.5M	+7.79M (+10.9%)
Value	$550.1M	$92.8K	$291.3M	−$258.8M (−47.0%)

1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (28)

Institutions that held Fulcrum Therapeutics, Inc. at the end of Q2 2026 but not at the end of Q1 2026.

Institutions new to FULC in Q2 2026
Institution	Shares	Value	% of portfolio
EcoR1 Capital, LLC	6,549,866	$24.0M	1.19%
Tang Capital Management LLC	6,521,412	$23.9M	1.08%
Marshall Wace, LLP	1,358,423	$4.97M	0.00%
Peapod Lane Capital LLC	285,798	$1.05M	0.71%
Hennion & Walsh Asset Management, Inc.	233,851	$855.9K	0.02%
Quadrature Capital Ltd	189,119	$692.2K	0.01%
Verdad Advisers, LP	125,224	$458.3K	0.44%
Rangeley Capital, LLC	114,890	$420.5K	0.41%
Headlands Technologies LLC	89,723	$328.4K	0.03%
Prelude Capital Management, LLC	67,857	$248.4K	0.02%
Alps Advisors Inc	67,632	$247.5K	0.00%
Fox Run Management, L.L.C.	56,446	$206.6K	0.03%
Marquette Asset Management, LLC	38,552	$141.1K	0.02%
State of Alaska, Department of Revenue	31,000	$113.0K	0.00%
SEI Investments Co	30,681	$112.3K	0.00%
Aigen Investment Management, LP	29,512	$108.0K	0.03%
Scientech Research LLC	28,584	$104.6K	0.08%
State Board of Administration of Florida Retirement System	25,052	$91.7K	0.00%
Rafferty Asset Management, LLC	24,538	$89.8K	0.00%
Castleview Partners, LLC	19,100	$69.9K	0.03%
Virtu Financial LLC	16,596	$61.0K	0.00%
Schonfeld Strategic Advisors LLC	16,078	$58.8K	0.00%
Jain Global LLC	15,260	$55.9K	0.00%
Guggenheim Capital LLC	10,583	$38.7K	0.00%
Wealth Enhancement Advisory Services, LLC	10,254	$35.9K	0.00%
Zions Bancorporation, National Association	97	$355	0.00%
Clearstead Advisors, LLC	54	$198	0.00%
Silver Grove Financial Group, Inc.	7	$26	0.00%

Sold out (42)

Institutions that held Fulcrum Therapeutics, Inc. at the end of Q1 2026 and filed for Q2 2026 without it.

Institutions that sold out of FULC in Q2 2026
Institution	Shares, Q1 2026	Value, Q1 2026
Ra Capital Management, L.P.	6,053,960	$46.4M
TCG Crossover Management, LLC	5,250,000	$40.3M
Braidwell LP	3,134,922	$24.0M
Siren, L.L.C.	2,350,000	$18.0M
First Turn Management, LLC	2,256,109	$17.3M
Standard Life Aberdeen plc	2,211,953	$17.0M
Jones Hill Capital LP	1,771,926	$13.6M
Alyeska Investment Group, L.P.	1,328,449	$10.2M
Vestal Point Capital, LP	1,100,000	$8.44M
Trexquant Investment LP	453,529	$3.48M
Silverarc Capital Management, LLC	419,949	$3.22M
DAFNA Capital Management LLC	205,000	$1.57M
State of Wisconsin Investment Board	154,435	$1.18M
Atom Investors LP	69,155	$530.4K
Burkehill Global Management, LP	50,000	$383.5K
Man Group plc	46,119	$353.7K
Marex Group plc	42,000	$322.1K
Simplex Trading, LLC	41,940	$321.7K
BIT Capital GmbH	40,000	$306.8K
Matisse Capital	39,649	$304.1K
Woodline Partners LP	30,793	$236.2K
Pale Fire Capital SE	26,100	$200.2K
Quantinno Capital Management LP	25,669	$196.9K
ExodusPoint Capital Management, LP	23,172	$177.7K
Virtus Investment Advisers, Inc.	20,974	$160.9K
DRW Securities, LLC	16,414	$125.9K
Bailard, Inc.	11,781	$90.4K
ProShare Advisors LLC	11,656	$89.4K
Entropy Technologies, LP	10,819	$83.0K
Clear Street Markets LLC	6,975	$53.5K
MAI Capital Management	1,866	$14.3K
State of Wyoming	1,815	$13.9K
Versant Capital Management, Inc	858	$6.58K
Massmutual Trust Co FSB	581	$4.46K
Larson Financial Group LLC	407	$3.12K
UMA Financial Services, Inc.	283	$2.17K
Twin Peaks Wealth Advisors, LLC	38	$291
US Bancorp	26	$199
JPL Wealth Management, LLC	17	$131
Root Financial Partners, LLC	14	$107
Keating Financial Advisory Services, Inc.	3	$23
Hughes Financial Services, LLC	1	$8

Not filed for Q2 2026 yet (1)

Institutions that held Fulcrum Therapeutics, Inc. at the end of Q1 2026 and haven't filed a 13F for Q2 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding FULC in Q1 2026 that haven't filed for Q2 2026
Institution	Shares, Q1 2026	Value, Q1 2026
CWM, LLC	12,094	$92.8K