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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2023

Institutional positions in Definium Therapeutics, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
104
+12 vs. Q3 2023
Shares held
4.88M
+1.01M (+26.0%) vs. Q3 2023
Total value
$17.9M
+$5.74M (+47.3%) vs. Q3 2023
New holders
21
22 more added
Sold out
9
20 more reduced

1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 104 institutions
Q1 2021: 8 institutionsQ2 2021: 156 institutionsQ3 2021: 175 institutionsQ4 2021: 176 institutionsQ1 2022: 159 institutionsQ2 2022: 156 institutionsQ3 2022: 101 institutionsQ4 2022: 104 institutionsQ1 2023: 89 institutionsQ2 2023: 84 institutionsQ3 2023: 93 institutionsQ4 2023: 104 institutionsQ1 2024: 135 institutionsQ2 2024: 152 institutionsQ3 2024: 158 institutionsQ4 2024: 174 institutionsQ1 2025: 191 institutionsQ2 2025: 183 institutionsQ3 2025: 196 institutionsQ4 2025: 209 institutionsQ1 2026: 248 institutionsQ2 2026: 362 institutions
Value heldQ4 2023: $17.9M
Q1 2021: $932.0KQ2 2021: $131.0MQ3 2021: $104.8MQ4 2021: $72.0MQ1 2022: $53.6MQ2 2022: $15.1MQ3 2022: $20.5MQ4 2022: $11.1MQ1 2023: $12.6MQ2 2023: $13.9MQ3 2023: $12.1MQ4 2023: $17.9MQ1 2024: $327.2MQ2 2024: $299.3MQ3 2024: $281.6MQ4 2024: $288.9MQ1 2025: $240.5MQ2 2025: $271.0MQ3 2025: $468.6MQ4 2025: $908.7MQ1 2026: $1.47BQ2 2026: $5.35B
Institutions holding DFTX and their total value by quarter
QuarterHoldersValue
Q2 2026362$5.35B
Q1 2026248$1.47B
Q4 2025209$908.7M
Q3 2025196$468.6M
Q2 2025183$271.0M
Q1 2025191$240.5M
Q4 2024174$288.9M
Q3 2024158$281.6M
Q2 2024152$299.3M
Q1 2024135$327.2M
Q4 2023104$17.9M
Q3 202393$12.1M
Q2 202384$13.9M
Q1 202389$12.6M
Q4 2022104$11.1M
Q3 2022101$20.5M
Q2 2022156$15.1M
Q1 2022159$53.6M
Q4 2021176$72.0M
Q3 2021175$104.8M
Q2 2021156$131.0M
Q1 20218$932.0K

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q3 2023.

Institutions holding DFTX in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Cutler Group LP129$00.00%+43+50.0%Added
PrairieView Partners, LLC4$00.00%00.0%Unchanged
TSFG, LLC24$00.00%00.0%Unchanged
Huntington National Bank1$10.00%00.0%Unchanged
Coppell Advisory Solutions LLC1$40.00%+1New
AdvisorNet Financial, Inc3$110.00%00.0%Unchanged
Rothschild Investment LLC3$110.00%+3New
Hexagon Capital Partners LLC4$150.00%+4New
Strategic Investment Solutions, Inc.6$220.00%−372−98.4%Reduced
Belmont Capital, LLC6$220.00%00.0%Unchanged
Glen Eagle Advisors, LLC6$220.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC6$220.00%+6New
Advisory Services Network, LLC9$330.00%+9New
JJJ Advisors Inc.10$370.00%00.0%Unchanged
Focused Wealth Management, Inc10$370.00%00.0%Unchanged
CNB Bank10$370.00%00.0%Unchanged
SJS Investment Consulting Inc.14$520.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co16$590.00%+16New
Castleview Partners, LLC16$590.00%+16New
Pacifica Partners Inc.20$700.00%00.0%Unchanged
Vima LLC19$700.00%+19New
HighMark Wealth Management LLC28$1020.00%00.0%Unchanged
SRS Capital Advisors, Inc.28$1030.00%00.0%Unchanged
Robbins Farley LLC28$1030.00%00.0%Unchanged
Nelson, Van Denburg & Campbell Wealth Management Group, LLC30$1090.00%+6+25.0%Added
IFP Advisors, Inc30$1100.00%00.0%Unchanged
Chesapeake Asset Management LLC33$1200.00%00.0%Unchanged
American Capital Advisory, LLC33$1210.00%+33New
Plante Moran Financial Advisors, LLC36$1320.00%00.0%Unchanged
Louisbourg Investments Inc.52$1900.00%+52New
Tradewinds Capital Management, LLC53$1940.00%00.0%Unchanged
Signature Resources Capital Management, LLC53$1940.00%+53New
US Bancorp66$2420.00%00.0%Unchanged
Arrow Financial Corp66$2420.00%00.0%Unchanged
Hollencrest Capital Management66$2420.00%00.0%Unchanged
Westside Investment Management, Inc.66$2420.00%00.0%Unchanged
Allworth Financial LP66$2420.00%00.0%Unchanged
Signaturefd, LLC68$2490.00%00.0%Unchanged
Fairman Group, LLC85$3110.00%+85New
Princeton Global Asset Management LLC100$3660.00%00.0%Unchanged
Farther Finance Advisors, LLC100$3660.00%00.0%Unchanged
Harbour Investments, Inc.100$3660.00%+90+900.0%Added
Albion Financial Group132$4840.00%−191−59.1%Reduced
GWM Advisors LLC148$5420.00%00.0%Unchanged
Wells Fargo & Company259$9480.00%+16+6.6%Added
Emfo, LLC300$1.10K0.00%00.0%Unchanged
Tortoise Investment Management, LLC400$1.46K0.00%00.0%Unchanged
UBS Group AG403$1.48K0.00%−4,111−91.1%Reduced
NVWM, LLC416$1.52K0.00%+416New
Parallel Advisors, LLC477$1.75K0.00%00.0%Unchanged
Householder Group Estate & Retirement Specialist, LLC600$2.00K0.00%+300+100.0%Added
Edmond de Rothschild Holding S.A.666$2.44K0.00%00.0%Unchanged
TD Waterhouse Canada Inc.657$2.92K0.00%−110−14.3%Reduced
Citadel Advisors LLC1,085$3.97K0.00%−60,603−98.2%Reduced
CWM, LLC1,268$5.00K0.00%−595−31.9%Reduced
National Bank of Canada1,667$6.00K0.00%+33+2.0%Added
Crewe Advisors LLC1,999$7.32K0.00%00.0%Unchanged
Toronto Dominion Bank2,157$7.89K0.00%−400−15.6%Reduced
Advisor Group Holdings, Inc.3,277$12.0K0.00%−1,638−33.3%Reduced
JPMorgan Chase & Co3,516$12.9K0.00%00.0%Unchanged
Royal Bank of Canada5,385$20.0K0.00%+939+21.1%Added
Deutsche Bank AG5,613$20.5K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)5,820$21.3K0.00%+5,687+4,275.9%Added
Simplex Trading, LLC8,977$32.0K0.00%−758−7.8%Reduced
Barclays PLC9,147$33.5K0.00%00.0%Unchanged
Wolverine Trading, LLC10,237$37.5K0.00%−4,381−30.0%Reduced
Federation des caisses Desjardins du Quebec14,187$51.8K0.00%00.0%Unchanged
Regal Investment Advisors LLC14,556$53.3K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC16,530$61.0K0.00%−421−2.5%Reduced
Y-Intercept (Hong Kong) Ltd16,853$61.7K0.01%+16,853New
Bailard, Inc.17,300$63.3K0.00%+17,300New
Mitchell McLeod Pugh & Williams Inc20,000$73.2K0.02%+20,000New
Morgan Stanley22,861$83.7K0.00%−12,741−35.8%Reduced
FMR LLC23,807$87.1K0.00%+6,551+38.0%Added
XTX Topco Ltd23,935$87.6K0.02%+23,935New
Rathbone Brothers plc25,000$91.5K0.00%00.0%Unchanged
Bank of America Corp32,042$117.3K0.00%+17,103+114.5%Added
LPL Financial LLC35,230$128.9K0.00%+14,079+66.6%Added
Jump Financial, LLC36,826$134.8K0.00%+2,826+8.3%Added
Kestra Private Wealth Services, LLC51,339$187.9K0.00%00.0%Unchanged
Cornercap Investment Counsel Inc56,957$208.5K0.03%00.0%Unchanged
Northern Trust Corp62,063$227.2K0.00%−193−0.3%Reduced
Bank of New York Mellon Corp62,246$227.8K0.00%−687−1.1%Reduced
Moloney Securities Asset Management, LLC69,511$254.4K0.04%+69,511New
Qube Research & Technologies Ltd93,649$342.8K0.00%+84,644+940.0%Added
Data Collective IV GP, LLC100,350$367.3K0.30%+10.0%Added
Millennium Management LLC107,839$394.7K0.00%−129,636−54.6%Reduced
Jane Street Group, LLC109,663$401.4K0.00%+93,079+561.3%Added
Group One Trading, L.P.110,428$404.2K0.01%−24,149−17.9%Reduced
Citigroup Inc111,374$407.6K0.00%+24,279+27.9%Added
Goldman Sachs Group Inc111,931$409.7K0.00%+85,025+316.0%Added
AdvisorShares Investments LLC112,774$412.8K0.10%−4,637−3.9%Reduced
Scotia Capital Inc.121,756$441.1K0.00%+121,756New
State Street Corp122,104$446.9K0.00%+104+0.1%Added
Two Sigma Investments, LP139,096$509.1K0.00%−18,343−11.7%Reduced
Boothbay Fund Management, LLC146,660$536.8K0.02%+146,660New
Cresset Asset Management, LLC154,498$565.5K0.00%−2,426−1.5%Reduced
Busey Wealth Management156,320$572.1K0.02%−50,000−24.2%Reduced
Charles Schwab Investment Management Inc191,874$702.3K0.00%+3,338+1.8%Added
Susquehanna International Group, LLP230,051$842.0K0.00%+36,169+18.7%Added