Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 156
- −1 vs. Q1 2022
- Shares held
- 22.9M
- −25.5M (−52.7%) vs. Q1 2022
- Total value
- $15.1M
- −$38.5M (−71.8%) vs. Q1 2022
- New holders
- 49
- 26 more added
- Sold out
- 50
- 42 more reduced
2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| HSBC Holdings PLC | 31,802 | $20.0K | 0.00% | −11,279−26.2% | Reduced |
| Alpine Global Management, LLC | 31,750 | $20.0K | 0.01% | 00.0% | Unchanged |
| tru Independence LLC | 32,293 | $21.0K | 0.01% | −135,000−80.7% | Reduced |
| Public Employees Retirement Association of Colorado | 28,200 | $23.0K | 0.00% | +28,200 | New |
| Wedbush Securities Inc | 36,000 | $23.0K | 0.00% | +36,000 | New |
| Private Advisor Group, LLC | 36,063 | $23.0K | 0.00% | +36,063 | New |
| Shell Asset Management Co | 37,982 | $24.0K | 0.00% | 00.0% | Unchanged |
| Jaffetilchin Investment Partners, LLC | 36,855 | $24.0K | 0.00% | +36,855 | New |
| Accurate Wealth Management, LLC | 40,240 | $26.0K | 0.01% | +5,900+17.2% | Added |
| Squarepoint Ops LLC | 41,688 | $27.0K | 0.00% | −36,444−46.6% | Reduced |
| Bank of New York Mellon Corp | 42,788 | $28.0K | 0.00% | −893,600−95.4% | Reduced |
| Quantum Private Wealth, LLC | 45,040 | $28.0K | 0.02% | +45,040 | New |
| Legal & General Group Plc | 44,895 | $29.0K | 0.00% | −39,659−46.9% | Reduced |
| Toronto Dominion Bank | 46,523 | $30.0K | 0.00% | +1,000+2.2% | Added |
| Creative Planning | 53,156 | $34.0K | 0.00% | −2,339−4.2% | Reduced |
| Exchange Traded Concepts, LLC | 59,592 | $38.0K | 0.00% | +46,039+339.7% | Added |
| Royal Bank of Canada | 64,922 | $41.0K | 0.00% | −27,721−29.9% | Reduced |
| Balyasny Asset Management LLC | 66,300 | $42.0K | 0.00% | +66,300 | New |
| Gofen & Glossberg LLC | 72,500 | $46.0K | 0.00% | 00.0% | Unchanged |
| Audent Global Asset Management, LLC | 78,000 | $50.0K | 0.04% | 00.0% | Unchanged |
| Scotia Capital Inc. | 91,545 | $58.0K | 0.00% | +7,762+9.3% | Added |
| Parallax Volatility Advisers, L.P. | 100,107 | $64.0K | 0.00% | +206+0.2% | Added |
| Ikarian Capital, LLC | 105,958 | $68.0K | 0.03% | 00.0% | Unchanged |
| Bank of America Corp | 106,081 | $68.0K | 0.00% | +58,618+123.5% | Added |
| Laurion Capital Management LP | 132,327 | $85.0K | 0.00% | +132,327 | New |
| Y-Intercept (Hong Kong) Ltd | 147,092 | $94.0K | 0.01% | +147,092 | New |
| Fore Capital, LLC | 160,000 | $102.0K | 0.26% | +60,000+60.0% | Added |
| HRT Financial LP | 173,838 | $111.0K | 0.00% | +161,728+1,335.5% | Added |
| Deutsche Bank AG | 178,535 | $115.0K | 0.00% | −187,757−51.3% | Reduced |
| Geode Capital Management, LLC | 201,145 | $129.0K | 0.00% | −2,621,537−92.9% | Reduced |
| Jane Street Group, LLC | 203,002 | $129.0K | 0.00% | −94,786−31.8% | Reduced |
| The PNC Financial Services Group, Inc. | 203,035 | $130.0K | 0.00% | +203,035 | New |
| BlackRock Inc. | 208,091 | $133.0K | 0.00% | −16,226,119−98.7% | Reduced |
| Commonwealth Equity Services, LLC | 225,971 | $144.0K | 0.00% | +40,346+21.7% | Added |
| Vanguard Group Inc | 230,252 | $147.0K | 0.00% | −1,672,898−87.9% | Reduced |
| Man Group plc | – | $148.0K | 0.00% | – | – |
| Bank of Montreal | 148,513 | $150.0K | 0.00% | +1,680+1.1% | Added |
| Goldman Sachs Group Inc | 261,290 | $167.0K | 0.00% | −86,487−24.9% | Reduced |
| Credit Suisse AG | 319,740 | $204.0K | 0.00% | +40,687+14.6% | Added |
| Two Sigma Investments, LP | 372,832 | $239.0K | 0.00% | −304,948−45.0% | Reduced |
| Penserra Capital Management LLC | 441,865 | $282.0K | 0.01% | −38,988−8.1% | Reduced |
| Cubist Systematic Strategies, LLC | 511,780 | $328.0K | 0.00% | +511,780 | New |
| Merit Financial Group, LLC | 532,387 | $341.0K | 0.01% | +532,387 | New |
| Group One Trading, L.P. | 566,863 | $363.0K | 0.01% | +31,658+5.9% | Added |
| Susquehanna International Group, LLP | 632,746 | $405.0K | 0.00% | −51,208−7.5% | Reduced |
| Morgan Stanley | 728,900 | $468.0K | 0.00% | −1,245,399−63.1% | Reduced |
| AdvisorShares Investments LLC | 750,151 | $480.0K | 0.13% | +100,983+15.6% | Added |
| LPL Financial LLC | 774,711 | $496.0K | 0.00% | +774,711 | New |
| Swiss National Bank | 848,400 | $539.0K | 0.00% | −102,700−10.8% | Reduced |
| State Street Corp | 962,810 | $616.0K | 0.00% | −5,182,693−84.3% | Reduced |
| Ergoteles LLC | 1,087,598 | $696.0K | 0.02% | +1,087,598 | New |
| Busey Wealth Management | 1,248,201 | $799.0K | 0.04% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,741,833 | $1.11M | 0.00% | +541,759+45.1% | Added |
| Data Collective IV GP, LLC | 1,505,248 | $1.23M | 1.02% | 00.0% | Unchanged |
| Millennium Management LLC | 5,075,110 | $3.25M | 0.00% | +4,638,774+1,063.1% | Added |
| JPMorgan Chase & Co | 261 | – | – | −151,049−99.8% | Reduced |
| Northern Trust Corp | 0 | $0 | 0.00% | −2,272,017−100.0% | Sold out |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −718,559−100.0% | Sold out |
| Rhumbline Advisers | 0 | $0 | 0.00% | −301,676−100.0% | Sold out |
| Alliancebernstein L.P. | 0 | $0 | 0.00% | −291,800−100.0% | Sold out |
| MMCAP International Inc. SPC | 0 | $0 | 0.00% | −240,300−100.0% | Sold out |
| American International Group, Inc. | 0 | $0 | 0.00% | −159,905−100.0% | Sold out |
| MetLife Investment Management | 0 | $0 | 0.00% | −146,176−100.0% | Sold out |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −137,970−100.0% | Sold out |
| Manufacturers Life Insurance Company, The | 0 | $0 | 0.00% | −135,904−100.0% | Sold out |
| HighTower Advisors, LLC | 0 | $0 | 0.00% | −104,975−100.0% | Sold out |
| Cresset Asset Management, LLC | 0 | $0 | 0.00% | −101,100−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −79,800−100.0% | Sold out |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −60,391−100.0% | Sold out |
| Principal Financial Group Inc | 0 | $0 | 0.00% | −58,480−100.0% | Sold out |
| Stifel Financial Corp | 0 | $0 | 0.00% | −49,740−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −47,944−100.0% | Sold out |
| State Board of Administration of Florida Retirement System | 0 | $0 | 0.00% | −48,230−100.0% | Sold out |
| Stratos Wealth Partners, LTD. | 0 | $0 | 0.00% | −33,604−100.0% | Sold out |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −29,492−100.0% | Sold out |
| Pictet Asset Management SA | 0 | $0 | 0.00% | −27,463−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −26,036−100.0% | Sold out |
| Ameritas Investment Partners, Inc. | 0 | $0 | 0.00% | −25,253−100.0% | Sold out |
| Nisa Investment Advisors, LLC | 0 | $0 | 0.00% | −21,940−100.0% | Sold out |
| Freestone Capital Holdings, LLC | 0 | $0 | 0.00% | −20,685−100.0% | Sold out |
| Mackenzie Financial Corp | 0 | $0 | 0.00% | −19,191−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −20,240−100.0% | Sold out |
| Close Asset Management Ltd | 0 | $0 | 0.00% | −16,000−100.0% | Sold out |
| Eudaimonia Partners, LLC | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| JSF Financial, LLC | 0 | $0 | 0.00% | −18,215−100.0% | Sold out |
| Beacon Pointe Advisors, LLC | 0 | $0 | 0.00% | −16,567−100.0% | Sold out |
| Metropolitan Life Insurance Co | 0 | $0 | 0.00% | −15,727−100.0% | Sold out |
| Xponance, Inc. | 0 | $0 | 0.00% | −15,230−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −13,201−100.0% | Sold out |
| EP Wealth Advisors, LLC | 0 | $0 | 0.00% | −12,372−100.0% | Sold out |
| Conservest Capital Advisors, Inc. | 0 | $0 | 0.00% | −11,944−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −11,040−100.0% | Sold out |
| Almanack Investment Partners, LLC. | 0 | $0 | 0.00% | −10,471−100.0% | Sold out |
| Chase Investment Counsel Corp | 0 | $0 | 0.00% | −10,375−100.0% | Sold out |
| Private Capital Group, LLC | 0 | $0 | 0.00% | −6,097−100.0% | Sold out |
| TFC Financial Management | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| RPg Family Wealth Advisory, LLC | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| 1832 Asset Management L.P. | 0 | $0 | 0.00% | −700−100.0% | Sold out |
| Pflug Koory, LLC | 0 | $0 | 0.00% | −520−100.0% | Sold out |
| Banque Cantonale Vaudoise | 0 | $0 | 0.00% | −763−100.0% | Sold out |