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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2021

Institutional positions in Definium Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
176
+7 vs. Q3 2021
Shares held
51.9M
+7.33M (+16.4%) vs. Q3 2021
Total value
$72.0M
−$32.6M (−31.1%) vs. Q3 2021
New holders
37
54 more added
Sold out
30
35 more reduced

6 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 176 institutions
Q1 2021: 8 institutionsQ2 2021: 156 institutionsQ3 2021: 175 institutionsQ4 2021: 176 institutionsQ1 2022: 159 institutionsQ2 2022: 156 institutionsQ3 2022: 101 institutionsQ4 2022: 104 institutionsQ1 2023: 89 institutionsQ2 2023: 84 institutionsQ3 2023: 93 institutionsQ4 2023: 104 institutionsQ1 2024: 135 institutionsQ2 2024: 152 institutionsQ3 2024: 158 institutionsQ4 2024: 174 institutionsQ1 2025: 191 institutionsQ2 2025: 183 institutionsQ3 2025: 196 institutionsQ4 2025: 209 institutionsQ1 2026: 248 institutionsQ2 2026: 362 institutions
Value heldQ4 2021: $72.0M
Q1 2021: $932.0KQ2 2021: $131.0MQ3 2021: $104.8MQ4 2021: $72.0MQ1 2022: $53.6MQ2 2022: $15.1MQ3 2022: $20.5MQ4 2022: $11.1MQ1 2023: $12.6MQ2 2023: $13.9MQ3 2023: $12.1MQ4 2023: $17.9MQ1 2024: $327.2MQ2 2024: $299.3MQ3 2024: $281.6MQ4 2024: $288.9MQ1 2025: $240.5MQ2 2025: $271.0MQ3 2025: $468.6MQ4 2025: $908.7MQ1 2026: $1.47BQ2 2026: $5.35B
Institutions holding DFTX and their total value by quarter
QuarterHoldersValue
Q2 2026362$5.35B
Q1 2026248$1.47B
Q4 2025209$908.7M
Q3 2025196$468.6M
Q2 2025183$271.0M
Q1 2025191$240.5M
Q4 2024174$288.9M
Q3 2024158$281.6M
Q2 2024152$299.3M
Q1 2024135$327.2M
Q4 2023104$17.9M
Q3 202393$12.1M
Q2 202384$13.9M
Q1 202389$12.6M
Q4 2022104$11.1M
Q3 2022101$20.5M
Q2 2022156$15.1M
Q1 2022159$53.6M
Q4 2021176$72.0M
Q3 2021175$104.8M
Q2 2021156$131.0M
Q1 20218$932.0K

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q3 2021.

Institutions holding DFTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Harbour Investments, Inc.161$00.00%−600−78.8%Reduced
Sargent Bickham Lagudis LLC160$00.00%−130−44.8%Reduced
Larson Financial Group LLC210$00.00%00.0%Unchanged
CNB Bank150$00.00%00.0%Unchanged
Pacifica Partners Inc.300$00.00%00.0%Unchanged
Montag A & Associates Inc57$00.00%00.0%Unchanged
Signaturefd, LLC30$00.00%00.0%Unchanged
Focused Wealth Management, Inc160$00.00%00.0%Unchanged
JJJ Advisors Inc.150$00.00%00.0%Unchanged
Gemmer Asset Management LLC20$00.00%00.0%Unchanged
Sterling Investment Advisors, Ltd.30$00.00%00.0%Unchanged
PrairieView Partners, LLC67$00.00%00.0%Unchanged
Bedel Financial Consulting, Inc.10$00.00%00.0%Unchanged
Belmont Capital, LLC100$00.00%00.0%Unchanged
Professional Financial Advisors, LLC84$00.00%00.0%Unchanged
Robbins Farley LLC220$00.00%+100+83.3%Added
Foresight Capital Management Advisors, Inc.288$00.00%+288New
Ford Financial Group, LLC200$00.00%+200New
Snowden Capital Advisors LLC200$00.00%+200New
Laffer Tengler Investments100$1380.00%00.0%Unchanged
Arrow Financial Corp1,000$1.00K0.00%00.0%Unchanged
American Research & Management Co.1,000$1.00K0.00%00.0%Unchanged
Westside Investment Management, Inc.1,000$1.00K0.00%00.0%Unchanged
Tradewinds Capital Management, LLC800$1.00K0.00%00.0%Unchanged
Banque Cantonale Vaudoise763$1.00K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.436$1.00K0.00%+50+13.0%Added
Pflug Koory, LLC520$1.00K0.00%00.0%Unchanged
TSFG, LLC380$1.00K0.00%00.0%Unchanged
Private Ocean, LLC400$1.00K0.00%+400New
Quadrant Capital Group LLC911$1.00K0.00%+911New
Burleson & Company, LLC1,301$2.00K0.00%00.0%Unchanged
Glassman Wealth Services2,500$3.00K0.00%00.0%Unchanged
US Bancorp2,000$3.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.2,395$3.00K0.00%00.0%Unchanged
Front Row Advisors LLC2,000$3.00K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.2,234$3.00K0.00%00.0%Unchanged
Baldrige Asset Management LLC2,000$3.00K0.00%00.0%Unchanged
TFC Financial Management2,000$3.00K0.00%+1,000+100.0%Added
Henrickson Nauta Wealth Advisors, Inc.3,000$3.00K0.00%+3,000New
Steward Partners Investment Advisory, LLC2,700$4.00K0.00%00.0%Unchanged
Rinkey Investments4,000$4.00K0.00%+4,000New
Kistler-Tiffany Companies, LLC3,275$5.00K0.00%00.0%Unchanged
Cardinal Capital Management, Inc.3,750$5.00K0.00%+3,750New
Concord Wealth Partners3,510$5.00K0.00%+3,510New
Clearstead Advisors, LLC4,405$6.00K0.00%+1,255+39.8%Added
SJS Investment Consulting Inc.4,030$6.00K0.00%+4,030New
Albion Financial Group4,870$7.00K0.00%00.0%Unchanged
Captrust Financial Advisors4,778$7.00K0.00%+725+17.9%Added
South State Corp.5,275$7.00K0.00%+5,275New
Private Capital Group, LLC6,097$8.00K0.00%00.0%Unchanged
Federated Hermes, Inc.6,081$8.00K0.00%−71−1.2%Reduced
Tortoise Investment Management, LLC6,000$8.00K0.00%00.0%Unchanged
Chase Investment Counsel Corp10,375$14.0K0.01%00.0%Unchanged
First National Trust Co10,000$14.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)10,104$14.0K0.00%+920+10.0%Added
Edmond de Rothschild Holding S.A.10,000$14.0K0.00%+10,000New
Aries Wealth Management10,000$14.0K0.01%+10,000New
NorthRock Partners, LLC10,781$15.0K0.00%+426+4.1%Added
Boothbay Fund Management, LLC11,040$15.0K0.00%+11,040New
Platform Technology Partners11,250$16.0K0.01%−3,750−25.0%Reduced
IFP Advisors, Inc11,057$16.0K0.00%−1,500−11.9%Reduced
American Century Companies Inc11,940$16.0K0.00%00.0%Unchanged
Profund Advisors LLC11,772$16.0K0.00%+1,590+15.6%Added
Sandy Spring Bank12,152$17.0K0.00%00.0%Unchanged
EP Wealth Advisors, LLC12,372$17.0K0.00%+12,372New
Bank Julius Baer & Co. Ltd, Zurich12,555$17.0K0.00%+12,555New
Belvedere Trading LLC19,035$18.0K0.00%−152,239−88.9%Reduced
Fulton Breakefield Broenniman LLC12,750$18.0K0.00%00.0%Unchanged
MAI Capital Management13,201$18.0K0.00%+13,201New
Schechter Investment Advisors, LLC13,006$18.0K0.00%+13,006New
Advisor Group Holdings, Inc.13,536$19.0K0.00%−59,756−81.5%Reduced
United Capital Financial Advisers, LLC13,579$19.0K0.00%−1,500−9.9%Reduced
CIBC World Markets Inc.15,546$21.0K0.00%+175+1.1%Added
Veritable, L.P.15,100$21.0K0.00%00.0%Unchanged
Gerber Kawasaki Wealth & Investment Management15,540$21.0K0.00%+15,531+172,566.7%Added
Bard Financial Services, Inc.15,000$21.0K0.00%+15,000New
TD Waterhouse Canada Inc.13,400$21.8K0.00%+13,400New
Close Asset Management Ltd16,000$22.0K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec16,559$22.8K0.00%−100−0.6%Reduced
Xponance, Inc.16,486$23.0K0.00%+117+0.7%Added
HRT Financial LP17,743$24.0K0.00%+17,743New
Mackenzie Financial Corp19,191$26.0K0.00%+277+1.5%Added
CWM, LLC19,642$27.0K0.00%+19,642New
Prudential Financial Inc20,240$28.0K0.00%−2,510−11.0%Reduced
Fisher Asset Management, LLC20,125$28.0K0.00%+20,125New
Regions Financial Corp20,000$28.0K0.00%+20,000New
K.J. Harrison & Partners Inc21,500$30.0K0.00%00.0%Unchanged
Price T Rowe Associates Inc22,986$32.0K0.00%−5,800−20.1%Reduced
Conservest Capital Advisors, Inc.23,695$33.0K0.00%+251+1.1%Added
Bayesian Capital Management, LP23,578$33.0K0.01%+23,578New
Ameritas Investment Partners, Inc.25,253$35.0K0.00%00.0%Unchanged
Private Advisor Group, LLC25,710$36.0K0.00%−34,794−57.5%Reduced
Simplex Trading, LLC28,219$38.0K0.00%−170,247−85.8%Reduced
IHT Wealth Management, LLC27,500$38.0K0.00%−2,500−8.3%Reduced
Pictet Asset Management SA27,463$38.0K0.00%00.0%Unchanged
Huntington National Bank30,001$41.0K0.00%−29,999−50.0%Reduced
Cutler Group LP29,889$41.0K0.00%−1,132−3.6%Reduced
American Portfolios Advisors30,000$41.4K0.00%00.0%Unchanged
Csenge Advisory Group12,112$42.0K0.00%−2,500−17.1%Reduced
Stratos Wealth Partners, LTD.33,604$46.0K0.00%00.0%Unchanged