Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 178
- +9 vs. Q3 2023
- Shares held
- 60.3M
- +1.65M (+2.8%) vs. Q3 2023
- Total value
- $887.4M
- −$186.2M (−17.3%) vs. Q3 2023
- New holders
- 37
- 78 more added
- Sold out
- 28
- 46 more reduced
1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Renaissance Technologies LLC | 71,288 | $1.05M | 0.00% | −78,812−52.5% | Reduced |
| JPMorgan Chase & Co | 71,888 | $1.06M | 0.00% | −19,077−21.0% | Reduced |
| ExodusPoint Capital Management, LP | 72,824 | $1.07M | 0.01% | −501,799−87.3% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 73,130 | $1.08M | 0.00% | −49,000−40.1% | Reduced |
| ADAR1 Capital Management, LLC | 77,558 | $1.14M | 0.51% | +77,558 | New |
| Swiss National Bank | 79,700 | $1.17M | 0.00% | +13,200+19.8% | Added |
| DekaBank Deutsche Girozentrale | 83,000 | $1.22M | 0.00% | +50,000+151.5% | Added |
| StemPoint Capital LP | 83,381 | $1.23M | 0.33% | +83,381 | New |
| Sectoral Asset Management Inc | 84,055 | $1.24M | 0.53% | +10,400+14.1% | Added |
| Hennion & Walsh Asset Management, Inc. | 84,930 | $1.25M | 0.07% | +35,364+71.3% | Added |
| Manufacturers Life Insurance Company, The | 85,648 | $1.26M | 0.00% | +58,518+215.7% | Added |
| Phocas Financial Corp. | 86,073 | $1.27M | 0.17% | +86,073 | New |
| Barclays PLC | 90,879 | $1.34M | 0.00% | +65,180+253.6% | Added |
| Federated Hermes, Inc. | 102,500 | $1.51M | 0.00% | −221,760−68.4% | Reduced |
| TD Asset Management Inc | 115,000 | $1.69M | 0.00% | +115,000 | New |
| Norges Bank | 116,400 | $1.71M | 0.00% | +116,400 | New |
| Altium Capital Management LP | 119,526 | $1.76M | 1.21% | −415,174−77.6% | Reduced |
| Bank of America Corp | 120,328 | $1.77M | 0.00% | +42,142+53.9% | Added |
| DAFNA Capital Management LLC | 122,547 | $1.80M | 0.43% | 00.0% | Unchanged |
| Simplex Trading, LLC | 129,422 | $1.91M | 0.06% | +106,870+473.9% | Added |
| Gsa Capital Partners LLP | 132,177 | $1.95M | 0.16% | +89,742+211.5% | Added |
| Algert Global LLC | 147,020 | $2.16M | 0.09% | −14,385−8.9% | Reduced |
| AlphaCentric Advisors LLC | 151,000 | $2.22M | 1.49% | +5,500+3.8% | Added |
| Primecap Management Co | 156,900 | $2.31M | 0.00% | −148,000−48.5% | Reduced |
| Twinbeech Capital LP | 166,444 | $2.45M | 0.04% | +84,860+104.0% | Added |
| Sphera Funds Management Ltd. | 183,650 | $2.70M | 0.50% | −10,000−5.2% | Reduced |
| Bank of New York Mellon Corp | 191,000 | $2.81M | 0.00% | +27,405+16.8% | Added |
| Standard Life Aberdeen plc | 195,493 | $2.88M | 0.01% | +195,493 | New |
| Tang Capital Management LLC | 200,000 | $2.94M | 0.27% | +200,000 | New |
| Boothbay Fund Management, LLC | 219,341 | $3.23M | 0.12% | +219,341 | New |
| Polar Asset Management Partners Inc. | 242,300 | $3.57M | 0.10% | +210,300+657.2% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 256,606 | $3.78M | 0.02% | +132,151+106.2% | Added |
| Trexquant Investment LP | 265,046 | $3.90M | 0.09% | +265,046 | New |
| Ally Bridge Group (NY) LLC | 275,773 | $4.06M | 2.92% | +3,083+1.1% | Added |
| Schroder Investment Management Group | 295,000 | $4.34M | 0.01% | +295,000 | New |
| Dark Forest Capital Management LP | 312,463 | $4.60M | 0.69% | +212,307+212.0% | Added |
| Charles Schwab Investment Management Inc | 387,620 | $5.71M | 0.00% | +21,758+5.9% | Added |
| Citigroup Inc | 387,664 | $5.71M | 0.01% | +343,875+785.3% | Added |
| Northern Trust Corp | 435,437 | $6.41M | 0.00% | +9,659+2.3% | Added |
| Cubist Systematic Strategies, LLC | 436,835 | $6.43M | 0.08% | +236,645+118.2% | Added |
| Hudson Bay Capital Management LP | 460,600 | $6.78M | 0.06% | −221,623−32.5% | Reduced |
| Voloridge Investment Management, LLC | 465,445 | $6.85M | 0.03% | +196,478+73.0% | Added |
| Woodline Partners LP | 470,801 | $6.93M | 0.08% | −428,499−47.6% | Reduced |
| Qube Research & Technologies Ltd | 482,599 | $7.10M | 0.02% | +319,889+196.6% | Added |
| Group One Trading, L.P. | 503,672 | $7.41M | 0.23% | +466,301+1,247.8% | Added |
| Rock Springs Capital Management LP | 535,012 | $7.88M | 0.19% | −1,010,004−65.4% | Reduced |
| American Century Companies Inc | 542,546 | $7.99M | 0.01% | +542,546 | New |
| D. E. Shaw & Co., Inc. | 546,965 | $8.05M | 0.01% | −213,325−28.1% | Reduced |
| Susquehanna International Group, LLP | 562,940 | $8.29M | 0.01% | +346,186+159.7% | Added |
| Walleye Capital LLC | 582,728 | $8.58M | 0.12% | +481,769+477.2% | Added |
| Nantahala Capital Management, LLC | 620,110 | $9.13M | 0.91% | +212,905+52.3% | Added |
| Emerald Mutual Fund Advisers Trust | 656,530 | $9.66M | 0.51% | −24,780−3.6% | Reduced |
| GMT Capital Corp | 786,000 | $11.6M | 0.44% | +209,700+36.4% | Added |
| Emerald Advisers, LLC | 802,610 | $11.8M | 0.51% | −35,962−4.3% | Reduced |
| Falcon Edge Capital, LP | 846,240 | $12.5M | 6.01% | −7,022−0.8% | Reduced |
| Deutsche Bank AG | 853,000 | $12.6M | 0.01% | +828,584+3,393.6% | Added |
| Ikarian Capital, LLC | 877,500 | $12.9M | 3.53% | +877,500 | New |
| Price T Rowe Associates Inc | 894,780 | $13.2M | 0.00% | +870,560+3,594.4% | Added |
| Marshall Wace, LLP | 985,114 | $14.5M | 0.03% | −212,646−17.8% | Reduced |
| Nuveen Asset Management, LLC | 1,021,657 | $15.0M | 0.00% | +21,306+2.1% | Added |
| Geode Capital Management, LLC | 1,030,716 | $15.2M | 0.00% | +48,648+5.0% | Added |
| Jupiter Asset Management Ltd | 1,060,900 | $15.6M | 0.15% | +411,164+63.3% | Added |
| Saturn V Capital Management LLC | 1,099,268 | $16.2M | 6.19% | +213,125+24.1% | Added |
| Eventide Asset Management, LLC | 1,116,837 | $16.4M | 0.27% | 00.0% | Unchanged |
| Jane Street Group, LLC | 1,157,165 | $17.0M | 0.02% | +555,877+92.4% | Added |
| Goldman Sachs Group Inc | 1,256,861 | $18.5M | 0.00% | +69,733+5.9% | Added |
| Franklin Resources Inc | 1,325,001 | $19.5M | 0.01% | +707,134+114.4% | Added |
| FMR LLC | 1,436,151 | $21.1M | 0.00% | +997,465+227.4% | Added |
| State Street Corp | 1,441,402 | $21.2M | 0.00% | +201,649+16.3% | Added |
| Perceptive Advisors LLC | 1,869,125 | $27.5M | 0.62% | −819,748−30.5% | Reduced |
| Citadel Advisors LLC | 2,240,885 | $33.0M | 0.03% | +1,013,941+82.6% | Added |
| Millennium Management LLC | 2,272,643 | $33.5M | 0.03% | +153,108+7.2% | Added |
| Stonepine Capital Management, LLC | 2,500,000 | $36.8M | 15.92% | −15,868−0.6% | Reduced |
| Point72 Asset Management, L.P. | 2,751,305 | $40.5M | 0.12% | +2,751,259+5,980,997.8% | Added |
| Morgan Stanley | 2,830,243 | $41.7M | 0.00% | +1,878,124+197.3% | Added |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,962,555 | $43.6M | 0.16% | 00.0% | Unchanged |
| BlackRock Inc. | 4,002,334 | $58.9M | 0.00% | +426,875+11.9% | Added |
| Vanguard Group Inc | 5,275,566 | $77.7M | 0.00% | +225,486+4.5% | Added |
| Boxer Capital, LLC | 0 | $0 | 0.00% | −2,084,000−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −1,700,200−100.0% | Sold out |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −1,259,335−100.0% | Sold out |
| Samlyn Capital, LLC | 0 | $0 | 0.00% | −1,164,897−100.0% | Sold out |
| Octagon Capital Advisors LP | 0 | $0 | 0.00% | −695,000−100.0% | Sold out |
| Gilder Gagnon Howe & Co LLC | 0 | $0 | 0.00% | −688,438−100.0% | Sold out |
| Tri Locum Partners LP | 0 | $0 | 0.00% | −282,862−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −267,694−100.0% | Sold out |
| Ghost Tree Capital, LLC | 0 | $0 | 0.00% | −215,000−100.0% | Sold out |
| Oberweis Asset Management Inc | 0 | $0 | 0.00% | −170,000−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −137,523−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −129,918−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −120,157−100.0% | Sold out |
| Aigen Investment Management, LP | 0 | $0 | 0.00% | −65,863−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −56,241−100.0% | Sold out |
| Moore Capital Management, LP | 0 | $0 | 0.00% | −47,078−100.0% | Sold out |
| Putnam Investments LLC | 0 | $0 | 0.00% | −46,460−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −35,000−100.0% | Sold out |
| Jackson Creek Investment Advisors LLC | 0 | $0 | 0.00% | −27,193−100.0% | Sold out |
| Axxcess Wealth Management, LLC | 0 | $0 | 0.00% | −26,151−100.0% | Sold out |
| Knoll Capital Management, LLC | 0 | $0 | 0.00% | −24,772−100.0% | Sold out |
| Millrace Asset Group, Inc. | 0 | $0 | 0.00% | −19,496−100.0% | Sold out |