Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q3 2023
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 170
- +18 vs. Q2 2023
- Shares held
- 58.9M
- +5.09M (+9.5%) vs. Q2 2023
- Total value
- $1.08B
- −$82.5M (−7.1%) vs. Q2 2023
- New holders
- 34
- 68 more added
- Sold out
- 16
- 48 more reduced
2 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Twinbeech Capital LP | 81,584 | $1.49M | 0.03% | −74,464−47.7% | Reduced |
| Caption Management, LLC | 89,256 | $1.63M | 0.21% | +52,256+141.2% | Added |
| JPMorgan Chase & Co | 90,965 | $1.67M | 0.00% | −99,331−52.2% | Reduced |
| Dark Forest Capital Management LP | 100,156 | $1.83M | 0.15% | +60,108+150.1% | Added |
| Walleye Capital LLC | 100,959 | $1.85M | 0.03% | +48,581+92.8% | Added |
| Alyeska Investment Group, L.P. | 120,157 | $2.20M | 0.02% | −200,000−62.5% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 122,130 | $2.24M | 0.01% | −45,000−26.9% | Reduced |
| DAFNA Capital Management LLC | 122,547 | $2.24M | 0.70% | +122,547 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 124,455 | $2.28M | 0.01% | +124,455 | New |
| Ameriprise Financial Inc | 129,918 | $2.38M | 0.00% | −254−0.2% | Reduced |
| Schonfeld Strategic Advisors LLC | 137,523 | $2.52M | 0.02% | −72,862−34.6% | Reduced |
| AlphaCentric Advisors LLC | 145,500 | $2.66M | 1.51% | +37,500+34.7% | Added |
| Renaissance Technologies LLC | 150,100 | $2.75M | 0.00% | +150,100 | New |
| Algert Global LLC | 161,405 | $2.96M | 0.14% | +161,405 | New |
| Qube Research & Technologies Ltd | 162,710 | $2.98M | 0.01% | +38,530+31.0% | Added |
| Bank of New York Mellon Corp | 163,595 | $3.00M | 0.00% | −286−0.2% | Reduced |
| Oberweis Asset Management Inc | 170,000 | $3.11M | 0.33% | +85,000+100.0% | Added |
| J. Goldman & Co LP | 184,907 | $3.39M | 0.17% | +85,567+86.1% | Added |
| Sphera Funds Management Ltd. | 193,650 | $3.55M | 0.85% | +93,650+93.7% | Added |
| Cubist Systematic Strategies, LLC | 200,190 | $3.67M | 0.05% | +145,942+269.0% | Added |
| Ghost Tree Capital, LLC | 215,000 | $3.94M | 1.91% | −335,000−60.9% | Reduced |
| Susquehanna International Group, LLP | 216,754 | $3.97M | 0.01% | +193,751+842.3% | Added |
| Verition Fund Management LLC | 267,694 | $4.90M | 0.07% | +46,561+21.1% | Added |
| Voloridge Investment Management, LLC | 268,967 | $4.92M | 0.02% | +154,338+134.6% | Added |
| Ally Bridge Group (NY) LLC | 272,690 | $4.99M | 5.86% | +272,690 | New |
| Tri Locum Partners LP | 282,862 | $5.18M | 1.66% | +282,862 | New |
| International Biotechnology Trust PLC | 295,000 | $5.40M | 1.82% | +270,000+1,080.0% | Added |
| Primecap Management Co | 304,900 | $5.58M | 0.00% | +304,900 | New |
| Federated Hermes, Inc. | 324,260 | $5.94M | 0.02% | −1,204,740−78.8% | Reduced |
| Charles Schwab Investment Management Inc | 365,862 | $6.70M | 0.00% | +40,380+12.4% | Added |
| Nantahala Capital Management, LLC | 407,205 | $7.46M | 0.95% | +242,705+147.5% | Added |
| Northern Trust Corp | 425,778 | $7.80M | 0.00% | −59,640−12.3% | Reduced |
| FMR LLC | 438,686 | $8.03M | 0.00% | −10,296−2.3% | Reduced |
| Altium Capital Management LP | 534,700 | $9.79M | 5.67% | +349,700+189.0% | Added |
| ExodusPoint Capital Management, LP | 574,623 | $10.5M | 0.13% | +61,532+12.0% | Added |
| GMT Capital Corp | 576,300 | $10.6M | 0.40% | +115,300+25.0% | Added |
| Jane Street Group, LLC | 601,288 | $11.0M | 0.02% | +127,895+27.0% | Added |
| Franklin Resources Inc | 617,867 | $11.3M | 0.01% | +589,381+2,069.0% | Added |
| Jupiter Asset Management Ltd | 649,736 | $11.9M | 0.13% | +649,736 | New |
| Emerald Mutual Fund Advisers Trust | 681,310 | $12.5M | 0.75% | +1,275+0.2% | Added |
| Hudson Bay Capital Management LP | 682,223 | $12.5M | 0.12% | +391,323+134.5% | Added |
| Gilder Gagnon Howe & Co LLC | 688,438 | $12.6M | 0.19% | +688,438 | New |
| Octagon Capital Advisors LP | 695,000 | $12.7M | 2.24% | +695,000 | New |
| Balyasny Asset Management LLC | 696,881 | $12.8M | 0.04% | −476,972−40.6% | Reduced |
| D. E. Shaw & Co., Inc. | 760,290 | $13.9M | 0.02% | −829,754−52.2% | Reduced |
| Emerald Advisers, LLC | 838,572 | $15.4M | 0.74% | +6,764+0.8% | Added |
| Falcon Edge Capital, LP | 853,262 | $15.6M | 9.88% | 00.0% | Unchanged |
| Saturn V Capital Management LLC | 886,143 | $16.2M | 6.79% | +886,143 | New |
| Woodline Partners LP | 899,300 | $16.5M | 0.19% | 00.0% | Unchanged |
| Morgan Stanley | 952,119 | $17.4M | 0.00% | −99,727−9.5% | Reduced |
| Geode Capital Management, LLC | 982,068 | $18.0M | 0.00% | +44,071+4.7% | Added |
| Nuveen Asset Management, LLC | 1,000,351 | $18.3M | 0.01% | +447,277+80.9% | Added |
| Eventide Asset Management, LLC | 1,116,837 | $20.4M | 0.37% | 00.0% | Unchanged |
| Voya Investment Management LLC | 1,145,788 | $21.0M | 0.02% | +208,248+22.2% | Added |
| Samlyn Capital, LLC | 1,164,897 | $21.3M | 0.38% | +1,164,897 | New |
| Goldman Sachs Group Inc | 1,187,128 | $21.7M | 0.01% | −163,350−12.1% | Reduced |
| Marshall Wace, LLP | 1,197,760 | $21.9M | 0.05% | −782,420−39.5% | Reduced |
| Citadel Advisors LLC | 1,226,944 | $22.5M | 0.02% | +413,619+50.9% | Added |
| State Street Corp | 1,239,753 | $22.7M | 0.00% | +82,054+7.1% | Added |
| Deep Track Capital, LP | 1,259,335 | $23.1M | 0.89% | +1,259,335 | New |
| Rock Springs Capital Management LP | 1,545,016 | $28.3M | 0.76% | +4000.0% | Added |
| Adage Capital Partners GP, L.L.C. | 1,700,200 | $31.1M | 0.07% | +932,000+121.3% | Added |
| Avidity Partners Management LP | 1,756,940 | $32.2M | 1.30% | +855,540+94.9% | Added |
| Boxer Capital, LLC | 2,084,000 | $38.2M | 2.03% | 00.0% | Unchanged |
| Millennium Management LLC | 2,119,535 | $38.8M | 0.04% | +197,904+10.3% | Added |
| Stonepine Capital Management, LLC | 2,515,868 | $46.1M | 15.30% | +1,394,840+124.4% | Added |
| Perceptive Advisors LLC | 2,688,873 | $49.2M | 1.66% | −2,185,046−44.8% | Reduced |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,962,555 | $54.2M | 0.22% | 00.0% | Unchanged |
| BlackRock Inc. | 3,575,459 | $65.5M | 0.00% | +70,174+2.0% | Added |
| Vanguard Group Inc | 5,050,080 | $92.5M | 0.00% | +124,188+2.5% | Added |
| Deerfield Management Company, L.P. (Series C) | 0 | $0 | 0.00% | −1,050,198−100.0% | Sold out |
| Great Point Partners LLC | 0 | $0 | 0.00% | −968,795−100.0% | Sold out |
| Lord, Abbett & Co. LLC | 0 | $0 | 0.00% | −244,493−100.0% | Sold out |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −120,000−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Norges Bank | 0 | $0 | 0.00% | −84,100−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −59,230−100.0% | Sold out |
| First Trust Advisors LP | 0 | $0 | 0.00% | −54,115−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −17,742−100.0% | Sold out |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −17,716−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −12,281−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −10,050−100.0% | Sold out |
| Tucker Asset Management LLC | 0 | $0 | 0.00% | −8,754−100.0% | Sold out |
| PEAK6 Investments LLC | 0 | $0 | 0.00% | −1,500−100.0% | Sold out |
| Connective Capital Management, LLC | 0 | $0 | 0.00% | −466−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −5−100.0% | Sold out |
| Pictet Asset Management SA | – | – | – | – | Not filed |
| Tekla Capital Management LLC | – | – | – | – | Not filed |