Skip to main content

Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q2 2023

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
154
+8 vs. Q1 2023
Shares held
54.5M
+3.18M (+6.2%) vs. Q1 2023
Total value
$1.18B
−$330.2M (−21.9%) vs. Q1 2023
New holders
29
66 more added
Sold out
21
43 more reduced

1 institution that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 154 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ2 2023: $1.18B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q1 2023.

Institutions holding AMLX in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Bank of America Corp117,211$2.53M0.00%+48,887+71.6%Added
Soleus Capital Management, L.P.120,000$2.59M0.29%+56,786+89.8%Added
Qube Research & Technologies Ltd124,180$2.68M0.01%+92,455+291.4%Added
Ameriprise Financial Inc130,172$2.81M0.00%−82,281−38.7%Reduced
Jump Financial, LLC141,447$3.05M0.11%+141,447New
Twinbeech Capital LP156,048$3.37M0.07%+24,276+18.4%Added
Bank of New York Mellon Corp163,881$3.53M0.00%−40,775−19.9%Reduced
Nantahala Capital Management, LLC164,500$3.55M0.43%+164,500New
Healthcare of Ontario Pension Plan Trust Fund167,130$3.60M0.02%+167,130New
Altium Capital Management LP185,000$3.99M3.12%00.0%Unchanged
JPMorgan Chase & Co190,296$4.10M0.00%+88,596+87.1%Added
Deutsche Bank AG191,611$4.13M0.00%+160,291+511.8%Added
Schonfeld Strategic Advisors LLC210,385$4.54M0.04%−74,620−26.2%Reduced
Verition Fund Management LLC221,133$4.77M0.07%−465−0.2%Reduced
Lord, Abbett & Co. LLC244,493$5.27M0.02%−5,549−2.2%Reduced
Hudson Bay Capital Management LP290,900$6.27M0.06%+290,900New
Alyeska Investment Group, L.P.320,157$6.91M0.05%+68,750+27.3%Added
Charles Schwab Investment Management Inc325,482$7.02M0.00%+5,396+1.7%Added
Sectoral Asset Management Inc387,310$8.35M1.39%+144,910+59.8%Added
FMR LLC448,982$9.68M0.00%+441,752+6,110.0%Added
GMT Capital Corp461,000$9.94M0.38%+461,000New
Jane Street Group, LLC473,393$10.2M0.01%+208,535+78.7%Added
Northern Trust Corp485,418$10.5M0.00%+21,538+4.6%Added
ExodusPoint Capital Management, LP513,091$11.1M0.13%+119,187+30.3%Added
Ghost Tree Capital, LLC550,000$11.9M4.28%+75,000+15.8%Added
Nuveen Asset Management, LLC553,074$11.9M0.00%−58,858−9.6%Reduced
Pictet Asset Management SA601,646$13.0M0.02%−832,200−58.0%Reduced
Emerald Mutual Fund Advisers Trust680,035$14.7M0.80%−109,556−13.9%Reduced
Adage Capital Partners GP, L.L.C.768,200$16.6M0.04%−239,136−23.7%Reduced
Citadel Advisors LLC813,325$17.5M0.02%+584,419+255.3%Added
Emerald Advisers, LLC831,808$17.9M0.79%−141,027−14.5%Reduced
Falcon Edge Capital, LP853,262$18.4M12.06%−77,075−8.3%Reduced
Woodline Partners LP899,300$19.4M0.23%+465,100+107.1%Added
Avidity Partners Management LP901,400$19.4M0.68%+1,400+0.2%Added
Voya Investment Management LLC937,540$20.2M0.02%+318,510+51.5%Added
Geode Capital Management, LLC937,997$20.2M0.00%+47,015+5.3%Added
Great Point Partners LLC968,795$20.9M4.19%+185,000+23.6%Added
Deerfield Management Company, L.P. (Series C)1,050,198$22.7M0.48%−934,135−47.1%Reduced
Morgan Stanley1,051,846$22.7M0.00%+149,299+16.5%Added
Eventide Asset Management, LLC1,116,837$24.1M0.41%+658,783+143.8%Added
Stonepine Capital Management, LLC1,121,028$24.2M8.72%+1,121,028New
State Street Corp1,157,699$25.0M0.00%+91,461+8.6%Added
Balyasny Asset Management LLC1,173,853$25.3M0.07%+753,012+178.9%Added
Goldman Sachs Group Inc1,350,478$29.1M0.01%−15,694−1.1%Reduced
Federated Hermes, Inc.1,529,000$33.0M0.08%−317,117−17.2%Reduced
Rock Springs Capital Management LP1,544,616$33.3M0.79%+91,800+6.3%Added
D. E. Shaw & Co., Inc.1,590,044$34.3M0.05%−432,326−21.4%Reduced
Millennium Management LLC1,921,631$41.4M0.04%+847,021+78.8%Added
Marshall Wace, LLP1,980,180$42.7M0.09%+840,940+73.8%Added
Boxer Capital, LLC2,084,000$45.0M2.08%00.0%Unchanged
Viking Global Investors LPSuperinvestorViking Global Investors2,962,555$63.9M0.26%00.0%Unchanged
BlackRock Inc.3,505,285$75.6M0.00%−109,633−3.0%Reduced
Perceptive Advisors LLC4,873,919$105.1M3.05%−1,160,725−19.2%Reduced
Vanguard Group Inc4,925,892$106.3M0.00%+178,551+3.8%Added
OrbiMed Advisors LLC0$00.00%−813,500−100.0%Sold out
Avoro Capital Advisors LLC0$00.00%−473,100−100.0%Sold out
Maven Securities LTD0$00.00%−100,000−100.0%Sold out
SEI Investments Co0$00.00%−69,665−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−30,857−100.0%Sold out
Seven Eight Capital, LP0$00.00%−30,053−100.0%Sold out
Pentwater Capital Management LP0$00.00%−30,000−100.0%Sold out
XTX Topco Ltd0$00.00%−14,751−100.0%Sold out
STRS Ohio0$00.00%−12,300−100.0%Sold out
Axq Capital, LP0$00.00%−10,600−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−10,150−100.0%Sold out
Ikarian Capital, LLC0$00.00%−10,000−100.0%Sold out
Boulder Hill Capital Management LP0$00.00%−9,400−100.0%Sold out
Artia Global Partners LP0$00.00%−8,339−100.0%Sold out
Quantbot Technologies LP0$00.00%−4,859−100.0%Sold out
Values First Advisors, Inc.0$00.00%−1,733−100.0%Sold out
Advisory Services Network, LLC0$00.00%−500−100.0%Sold out
TCI Wealth Advisors, Inc.0$00.00%−142−100.0%Sold out
The PNC Financial Services Group, Inc.0$00.00%−100−100.0%Sold out
Ellevest, Inc.0$00.00%−32−100.0%Sold out
US Bancorp0$00.00%−18−100.0%Sold out
Kula Investments, LLC––––Not filed