Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 127
- −3 vs. Q4 2024
- Shares held
- 166.9M
- −74.2K (0.0%) vs. Q4 2024
- Total value
- $232.0M
- −$56.8M (−19.7%) vs. Q4 2024
- New holders
- 22
- 38 more added
- Sold out
- 25
- 31 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Barclays PLC | 708,966 | $985.5K | 0.00% | +373,728+111.5% | Added |
| Sands Capital Ventures, LLC | 724,873 | $1.01M | 0.25% | 00.0% | Unchanged |
| Superstring Capital Management LP | 755,599 | $1.05M | 1.25% | +755,599 | New |
| Quantum Private Wealth, LLC | 791,476 | $1.10M | 0.42% | −3,500−0.4% | Reduced |
| Woodline Partners LP | 858,254 | $1.19M | 0.01% | −169,268−16.5% | Reduced |
| JPMorgan Chase & Co | 1,003,067 | $1.39M | 0.00% | −1,640,688−62.1% | Reduced |
| ADAR1 Capital Management, LLC | 1,066,309 | $1.48M | 0.29% | +888,602+500.0% | Added |
| B Group, Inc. | 1,255,556 | $1.75M | 1.52% | +290,000+30.0% | Added |
| Palo Alto Investors LP | 1,419,468 | $1.97M | 0.38% | +608,200+75.0% | Added |
| Northern Trust Corp | 1,431,666 | $1.99M | 0.00% | −27,066−1.9% | Reduced |
| Granahan Investment Management Inc | 1,640,793 | $2.28M | 0.11% | +4,412+0.3% | Added |
| Millennium Management LLC | 1,772,654 | $2.46M | 0.00% | +1,621,040+1,069.2% | Added |
| Polar Capital Holdings Plc | 3,000,000 | $4.17M | 0.03% | 00.0% | Unchanged |
| State Street Corp | 3,233,512 | $4.49M | 0.00% | −3,240,855−50.1% | Reduced |
| Geode Capital Management, LLC | 3,664,732 | $5.10M | 0.00% | +92,383+2.6% | Added |
| Tybourne Capital Management (HK) Ltd | 3,700,000 | $5.14M | 21.83% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 4,004,756 | $5.57M | 0.06% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 4,569,678 | $6.35M | 0.02% | +4,569,678 | New |
| Siren, L.L.C. | 6,514,737 | $9.06M | 0.51% | −87,738−1.3% | Reduced |
| Vanguard Group Inc | 8,770,921 | $12.2M | 0.00% | −135,843−1.5% | Reduced |
| Octagon Capital Advisors LP | 10,700,000 | $14.9M | 3.23% | +250,000+2.4% | Added |
| Ra Capital Management, L.P. | 10,872,503 | $15.1M | 0.25% | 00.0% | Unchanged |
| BlackRock, Inc. | 13,589,178 | $18.9M | 0.00% | +57,711+0.4% | Added |
| FMR LLC | 15,631,954 | $21.7M | 0.00% | −733,710−4.5% | Reduced |
| Morgan Stanley | 16,846,374 | $23.4M | 0.00% | −793,992−4.5% | Reduced |
| RTW Investments, LP | 18,787,866 | $26.1M | 0.40% | +10,115,236+116.6% | Added |
| Avoro Capital Advisors LLC | 19,999,999 | $27.8M | 0.43% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −5,000,000−100.0% | Sold out |
| VR Adviser, LLC | 0 | $0 | 0.00% | −3,225,180−100.0% | Sold out |
| Norges Bank | 0 | $0 | 0.00% | −1,461,120−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −884,244−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −878,448−100.0% | Sold out |
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −252,257−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −211,842−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −169,575−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −138,111−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −107,544−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −78,246−100.0% | Sold out |
| LPL Financial LLC | 0 | $0 | 0.00% | −60,000−100.0% | Sold out |
| Profund Advisors LLC | 0 | $0 | 0.00% | −50,242−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −35,808−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −34,098−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −31,597−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −28,498−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −22,432−100.0% | Sold out |
| E Fund Management Co., Ltd. | 0 | $0 | 0.00% | −17,844−100.0% | Sold out |
| Ground Swell Capital, LLC | 0 | $0 | 0.00% | −14,660−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −12,300−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −4,500−100.0% | Sold out |
| Rothschild Investment LLC | 0 | $0 | 0.00% | −130−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −130−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −154−100.0% | Sold out |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |