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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Taysha Gene Therapies, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
87
+24 vs. Q3 2023
Shares held
130.1M
+159.8K (+0.1%) vs. Q3 2023
Total value
$230.3M
−$180.3M (−43.9%) vs. Q3 2023
New holders
32
30 more added
Sold out
8
11 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 87 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ4 2023: $230.3M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q3 2023.

Institutions holding TSHA in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC79$00.00%00.0%Unchanged
Signaturefd, LLC50$890.00%+50New
Advisor Group Holdings, Inc.134$2380.00%00.0%Unchanged
Morton Brown Family Wealth, LLC260$4600.00%+260New
Allworth Financial LP1,000$1.77K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,871$5.08K0.00%+2,871New
UBS Group AG3,943$6.98K0.00%+3,393+616.9%Added
Wells Fargo & Company7,429$13.1K0.00%+889+13.6%Added
Leonteq Securities AG8,000$14.2K0.00%+3,000+60.0%Added
Quarry LP8,000$14.2K0.01%+8,000New
Lazard Asset Management LLC8,805$15.0K0.00%+8,805New
Capital Investment Advisors, LLC10,000$17.7K0.00%00.0%Unchanged
Royal Capital Wealth Management, LLC10,665$18.9K0.02%+10,665New
Camelot Portfolios, LLC11,000$19.5K0.01%+11,000New
ProShare Advisors LLC11,946$21.1K0.00%+11,946New
Group One Trading, L.P.12,032$21.3K0.00%+6,410+114.0%Added
Howard Capital Management Inc.14,165$25.1K0.00%+14,165New
Victory Capital Management Inc15,600$27.6K0.00%+15,600New
Charles Schwab Investment Management Inc16,140$28.6K0.00%00.0%Unchanged
XTX Topco Ltd16,285$28.8K0.01%+16,285New
Two Sigma Securities, LLC17,202$30.4K0.00%−10,435−37.8%Reduced
Dynamic Technology Lab Private Ltd17,389$31.0K0.00%+17,389New
Prudential Financial Inc19,050$33.7K0.00%+1,800+10.4%Added
Lee Financial Co20,000$35.4K0.01%00.0%Unchanged
China Universal Asset Management Co., Ltd.21,622$38.3K0.01%+21,622New
Engineers Gate Manager LP21,696$38.4K0.00%+21,696New
Virtu Financial LLC26,070$46.0K0.00%+26,070New
Commonwealth Equity Services, LLC26,769$47.0K0.00%−202−0.7%Reduced
Graham Capital Management, L.P.28,477$50.4K0.00%+28,477New
Connor, Clark & Lunn Investment Management Ltd.35,400$62.7K0.00%+35,400New
JPMorgan Chase & Co36,484$64.6K0.00%+36,347+26,530.7%Added
Jane Street Group, LLC42,278$74.8K0.00%+42,278New
Redwood Wealth Management Group, LLC42,600$75.4K0.08%+4,400+11.5%Added
Williams & Novak, LLC45,000$79.7K0.09%+45,000New
Dynamic Advisor Solutions LLC45,000$80.1K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC48,434$85.7K0.00%+48,434New
LPL Financial LLC58,060$102.8K0.00%+1,125+2.0%Added
Bank of New York Mellon Corp58,140$102.9K0.00%+32,066+123.0%Added
Manufacturers Life Insurance Company, The61,547$108.9K0.00%00.0%Unchanged
Squarepoint Ops LLC63,477$112.4K0.00%+34,909+122.2%Added
Diametric Capital, LP68,871$121.9K0.07%−691,143−90.9%Reduced
Goldman Sachs Group Inc83,474$147.7K0.00%+83,474New
Chicago Partners Investment Group LLC134,851$198.2K0.01%+23,740+21.4%Added
Qube Research & Technologies Ltd118,521$209.8K0.00%+118,521New
Bank of America Corp122,328$216.5K0.00%+84,148+220.4%Added
Two Sigma Investments, LP136,973$242.4K0.00%+136,973New
State Street Corp143,220$253.5K0.00%+3,200+2.3%Added
TD Asset Management Inc175,600$310.8K0.00%00.0%Unchanged
Polar Asset Management Partners Inc.186,700$330.5K0.01%+186,700New
Prelude Capital Management, LLC189,876$336.1K0.03%−50,375−21.0%Reduced
ADAR1 Capital Management, LLC209,000$369.9K0.17%+209,000New
Northern Trust Corp213,721$378.3K0.00%+147,531+222.9%Added
Morgan Stanley216,538$383.3K0.00%+44,469+25.8%Added
Kovitz Investment Group Partners, LLC277,778$491.7K0.01%+252,778+1,011.1%Added
EntryPoint Capital, LLC291,616$516.2K0.49%+291,616New
Monaco Asset Management SAM295,000$522.1K0.20%+295,000New
Citigroup Inc310,963$550.4K0.00%+29,844+10.6%Added
Adage Capital Partners GP, L.L.C.420,000$743.4K0.00%−1,080,000−72.0%Reduced
Acadian Asset Management LLC460,066$813.0K0.00%+460,066New
Palo Alto Investors LP529,861$937.9K0.08%+529,861New
Quantum Private Wealth, LLC639,520$1.13M0.47%+64,140+11.1%Added
Alphabet Inc.640,882$1.13M0.05%00.0%Unchanged
Exome Asset Management LLC693,300$1.23M1.21%+693,300New
Sands Capital Ventures, LLC724,873$1.28M0.36%00.0%Unchanged
Geode Capital Management, LLC985,421$1.74M0.00%+523,755+113.4%Added
Renaissance Technologies LLC1,097,400$1.94M0.00%+499,400+83.5%Added
Schonfeld Strategic Advisors LLC1,119,375$1.98M0.02%+399,332+55.5%Added
Price T Rowe Associates Inc1,227,333$2.17M0.00%−20,138−1.6%Reduced
Susquehanna International Group, LLP1,428,146$2.53M0.00%+1,225,529+604.9%Added
Ghost Tree Capital, LLC2,100,000$3.72M2.14%+775,000+58.5%Added
Citadel Advisors LLC2,297,556$4.07M0.00%+2,297,556New
Polar Capital Holdings Plc2,518,909$4.46M0.03%−11,091−0.4%Reduced
Point72 Asset Management, L.P.2,688,000$4.76M0.01%+1,751,450+187.0%Added
BlackRock Inc.2,699,238$4.78M0.00%+1,951,170+260.8%Added
TCG Crossover Management, LLC2,912,861$5.16M0.57%−8,198,250−73.8%Reduced
Millennium Management LLC3,380,532$5.98M0.01%+3,380,532New
Acuta Capital Partners, LLC3,589,333$6.35M3.58%−238,593−6.2%Reduced
Artal Group S.A.3,663,104$6.48M0.22%00.0%Unchanged
Tybourne Capital Management (HK) Ltd3,700,000$6.55M0.98%+2,200,000+146.7%Added
Eversept Partners, LP3,780,714$6.69M0.66%+2,074,940+121.6%Added
Baker Bros. Advisors LP4,004,756$7.09M0.08%+1,500,000+59.9%Added
Avoro Capital Advisors LLC4,355,555$7.71M0.11%+430,555+11.0%Added
Vanguard Group Inc6,195,567$11.0M0.00%+867,703+16.3%Added
VR Adviser, LLC10,412,872$18.4M1.26%−4,031,572−27.9%Reduced
RTW Investments, LP16,893,185$29.9M0.47%00.0%Unchanged
Ra Capital Management, L.P.18,472,503$32.7M0.51%00.0%Unchanged
FMR LLC22,439,124$39.7M0.00%−2,088,677−8.5%Reduced
Kynam Capital Management, LP0$00.00%−3,281,313−100.0%Sold out
Octagon Capital Advisors LP0$00.00%−2,777,778−100.0%Sold out
Franklin Resources Inc0$00.00%−810,840−100.0%Sold out
EAM Investors, LLC0$00.00%−335,390−100.0%Sold out
Bridgeway Capital Management, LLC0$00.00%−156,300−100.0%Sold out
Verition Fund Management LLC0$00.00%−85,034−100.0%Sold out
Simplex Trading, LLC0$00.00%−14,639−100.0%Sold out
Royal Bank of Canada0$00.00%−19−100.0%Sold out