Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 304
- +23 vs. Q1 2026
- Shares held
- 77.2M
- +4.58M (+6.3%) vs. Q1 2026
- Total value
- $8.55B
- +$2.21B (+34.8%) vs. Q1 2026
- New holders
- 64
- 105 more added
- Sold out
- 41
- 101 more reduced
4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Canada Pension Plan Investment Board | 47,400 | $5.26M | 0.00% | +47,400 | New |
| Nan Fung Group Holdings Ltd | 49,120 | $5.45M | 4.15% | 00.0% | Unchanged |
| Man Group plc | 50,788 | $5.64M | 0.01% | +46,766+1,162.8% | Added |
| Vanguard Asset Management, Ltd | 53,279 | $5.92M | 0.00% | +3,590+7.2% | Added |
| Trexquant Investment LP | 56,248 | $6.25M | 0.04% | +56,248 | New |
| Manufacturers Life Insurance Company, The | 57,170 | $6.35M | 0.00% | +6,401+12.6% | Added |
| Raymond James Financial Inc | 58,069 | $6.45M | 0.00% | +8,149+16.3% | Added |
| Citigroup Inc | 58,347 | $6.48M | 0.00% | +46,011+373.0% | Added |
| AQR Capital Management LLC | 59,208 | $6.57M | 0.00% | −71−0.1% | Reduced |
| ExodusPoint Capital Management, LP | 61,147 | $6.79M | 0.06% | +43,372+244.0% | Added |
| Blue Owl Capital Holdings LP | 61,455 | $6.82M | 1.04% | 00.0% | Unchanged |
| California State Teachers Retirement System | 64,031 | $7.11M | 0.01% | −1,775−2.7% | Reduced |
| Picton Mahoney Asset Management | 65,880 | $7.31M | 0.07% | +15,508+30.8% | Added |
| Renaissance Technologies LLC | 68,281 | $7.58M | 0.01% | −189,730−73.5% | Reduced |
| Capital Fund Management S.A. | 68,548 | $7.61M | 0.05% | +68,548 | New |
| Prudential Financial Inc | 69,145 | $7.68M | 0.01% | +38,955+129.0% | Added |
| Wells Fargo & Company | 72,147 | $8.01M | 0.00% | +38,039+111.5% | Added |
| Rhumbline Advisers | 73,333 | $8.14M | 0.01% | +3,475+5.0% | Added |
| Silvercrest Asset Management Group LLC | 73,432 | $8.15M | 0.05% | +26,545+56.6% | Added |
| Atom Investors LP | 73,465 | $8.16M | 0.73% | +16,465+28.9% | Added |
| WCM Investment Management, LLC | 80,552 | $8.86M | 0.02% | −68−0.1% | Reduced |
| Sphera Funds Management Ltd. | 80,400 | $8.93M | 1.28% | +80,400 | New |
| Neuberger Berman Group LLC | 83,035 | $9.22M | 0.01% | +9,601+13.1% | Added |
| Granahan Investment Management Inc | 83,270 | $9.25M | 0.33% | +5,561+7.2% | Added |
| Algert Global LLC | 83,431 | $9.26M | 0.11% | +24,918+42.6% | Added |
| First Light Asset Management, LLC | 85,765 | $9.52M | 0.58% | −1,416−1.6% | Reduced |
| Russell Investments Group, Ltd. | 86,709 | $9.63M | 0.01% | −29,003−25.1% | Reduced |
| Axiom Investors LLC | 86,880 | $9.65M | 0.08% | −4,869−5.3% | Reduced |
| Standard Life Aberdeen plc | 94,946 | $10.5M | 0.01% | +15,589+19.6% | Added |
| PFM Health Sciences, LP | 101,550 | $11.3M | 0.98% | −35,071−25.7% | Reduced |
| Swiss National Bank | 109,700 | $12.2M | 0.01% | −2,500−2.2% | Reduced |
| Longaeva Partners L.P. | 110,074 | $12.2M | 0.35% | +110,074 | New |
| Deutsche Bank AG | 115,232 | $12.8M | 0.00% | −26,369−18.6% | Reduced |
| Segall Bryant & Hamill, LLC | 121,866 | $13.5M | 0.16% | +121,866 | New |
| Opaleye Management Inc. | 122,500 | $13.6M | 1.23% | −500−0.4% | Reduced |
| Logos Global Management LP | 125,000 | $13.9M | 0.60% | −325,000−72.2% | Reduced |
| SummitTX Capital, L.P. | 126,401 | $14.0M | 0.37% | −39,198−23.7% | Reduced |
| Driehaus Capital Management LLC | 129,285 | $14.4M | 0.08% | −307,261−70.4% | Reduced |
| NEXTBio Capital Management LP | 131,758 | $14.6M | 6.73% | +5,680+4.5% | Added |
| Qube Research & Technologies Ltd | 134,410 | $14.9M | 0.02% | −143,533−51.6% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 135,867 | $15.1M | 0.03% | −15,975−10.5% | Reduced |
| ADAR1 Capital Management, LLC | 136,158 | $15.1M | 0.71% | −75,292−35.6% | Reduced |
| Nicholas Investment Partners, LP | 139,270 | $15.5M | 0.87% | +139,270 | New |
| UBS Group AG | 144,378 | $16.0M | 0.00% | −87,272−37.7% | Reduced |
| New York State Common Retirement Fund | 148,152 | $16.4M | 0.02% | +22,945+18.3% | Added |
| First Turn Management, LLC | 154,018 | $17.1M | 1.83% | +154,018 | New |
| Schroder Investment Management Group | 160,518 | $17.7M | 0.01% | +28,844+21.9% | Added |
| Assenagon Asset Management S.A. | 186,491 | $20.7M | 0.03% | +186,491 | New |
| Kennedy Capital Management, Inc. | 193,215 | $21.5M | 0.38% | +127,397+193.6% | Added |
| BNP Paribas Arbitrage, SA | 197,374 | $21.9M | 0.01% | −50,502−20.4% | Reduced |
| Nuveen, LLC | 203,078 | $22.5M | 0.01% | +85,702+73.0% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 203,618 | $22.6M | 0.52% | +203,618 | New |
| Capital World Investors | 221,450 | $24.6M | 0.00% | +105,757+91.4% | Added |
| Voya Investment Management LLC | 272,974 | $30.3M | 0.03% | +39,164+16.8% | Added |
| Silverarc Capital Management, LLC | 311,461 | $34.6M | 3.85% | +5,461+1.8% | Added |
| Millennium Management LLC | 316,719 | $35.2M | 0.02% | −135,106−29.9% | Reduced |
| OrbiMed Advisors LLC | 322,900 | $35.9M | 0.68% | +8,800+2.8% | Added |
| Bank of America Corp | 325,470 | $36.1M | 0.00% | −303,197−48.2% | Reduced |
| Artisan Partners Limited Partnership | 354,816 | $39.4M | 0.06% | −35,853−9.2% | Reduced |
| Braidwell LP | 381,128 | $42.3M | 1.57% | +70,500+22.7% | Added |
| Bank of New York Mellon Corp | 394,044 | $43.8M | 0.01% | +100,746+34.3% | Added |
| Adage Capital Partners GP, L.L.C. | 397,000 | $44.1M | 0.06% | −328,744−45.3% | Reduced |
| Ameriprise Financial Inc | 401,634 | $44.6M | 0.01% | +17,677+4.6% | Added |
| Sofinnova Investments, Inc. | 408,027 | $45.3M | 2.42% | −42,069−9.3% | Reduced |
| Point72 Asset Management, L.P. | 414,210 | $46.0M | 0.07% | −432,591−51.1% | Reduced |
| Squarepoint Ops LLC | 422,921 | $47.0M | 0.09% | +159,953+60.8% | Added |
| Candriam Luxembourg S.C.A. | 433,025 | $48.0M | 0.22% | −31,315−6.7% | Reduced |
| Loomis Sayles & Co L P | 434,102 | $48.2M | 0.06% | −31,000−6.7% | Reduced |
| Vanguard Fiduciary Trust Co | 445,723 | $49.5M | 0.01% | +23,812+5.6% | Added |
| Wellington Management Group LLP | 488,747 | $54.3M | 0.01% | +214,990+78.5% | Added |
| UBS Asset Management Americas Inc | 514,850 | $57.2M | 0.01% | −26,600−4.9% | Reduced |
| Northern Trust Corp | 540,332 | $60.0M | 0.01% | +41,818+8.4% | Added |
| Invesco Ltd. | 543,271 | $60.3M | 0.00% | +178,965+49.1% | Added |
| Integral Health Asset Management, LLC | 550,000 | $61.1M | 2.51% | −50,000−8.3% | Reduced |
| Charles Schwab Investment Management Inc | 552,738 | $61.4M | 0.01% | +26,279+5.0% | Added |
| Franklin Resources Inc | 577,033 | $64.1M | 0.01% | −49,812−7.9% | Reduced |
| Norges Bank | 685,844 | $76.1M | 0.01% | +685,844 | New |
| Rock Springs Capital Management LP | 692,598 | $76.9M | 3.75% | +2,850+0.4% | Added |
| Clearbridge Investments, LLC | 696,473 | $77.3M | 0.06% | +87,036+14.3% | Added |
| Alliancebernstein L.P. | 894,723 | $77.8M | 0.03% | −15,690−1.7% | Reduced |
| Woodline Partners LP | 758,891 | $84.3M | 0.26% | 00.0% | Unchanged |
| Jupiter Topco LLC | 925,490 | $102.8M | 0.04% | +925,490 | New |
| Pictet Asset Management Holding SA | 957,785 | $106.3M | 0.10% | +290,739+43.6% | Added |
| FMR LLC | 1,025,840 | $113.9M | 0.00% | −663,831−39.3% | Reduced |
| Morgan Stanley | 1,112,240 | $123.5M | 0.01% | +408,262+58.0% | Added |
| Siren, L.L.C. | 1,136,275 | $126.2M | 2.56% | +410,764+56.6% | Added |
| Checkpoint Capital L.P. | 1,186,000 | $131.7M | 33.79% | −41,200−3.4% | Reduced |
| Citadel Advisors LLC | 1,263,652 | $140.3M | 0.08% | −154,967−10.9% | Reduced |
| Capital Research Global Investors | 1,532,303 | $170.1M | 0.02% | +416,843+37.4% | Added |
| Geode Capital Management, LLC | 1,533,698 | $170.3M | 0.01% | +117,429+8.3% | Added |
| Polar Capital Holdings Plc | 1,663,632 | $184.7M | 0.52% | +48,046+3.0% | Added |
| Federated Hermes, Inc. | 1,785,716 | $198.3M | 0.29% | +499,413+38.8% | Added |
| Goldman Sachs Group Inc | 2,126,502 | $236.1M | 0.02% | +161,070+8.2% | Added |
| Westfield Capital Management Co LP | 2,208,595 | $245.2M | 0.80% | +279,472+14.5% | Added |
| Price T Rowe Associates Inc | 2,566,171 | $284.9M | 0.03% | +911,295+55.1% | Added |
| State Street Corp | 2,573,529 | $285.7M | 0.01% | +301,678+13.3% | Added |
| Perceptive Advisors LLC | 2,586,295 | $287.2M | 4.46% | +212,500+9.0% | Added |
| JPMorgan Chase & Co | 2,652,746 | $292.2M | 0.02% | +1,099,102+70.7% | Added |
| Vanguard Capital Management LLC | 3,005,977 | $333.8M | 0.01% | +38,152+1.3% | Added |
| Vanguard Portfolio Management LLC | 3,136,895 | $348.3M | 0.02% | +96,177+3.2% | Added |